Monocytic leukaemia

CD2_MONOCYTIC_LEUKAEMIA_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C93
  • Hospital discharge: ICD-9 206
  • Hospital discharge: ICD-8 206
  • Cause of death: ICD-10 C93
  • Cause of death: ICD-9 206
  • Cause of death: ICD-8 206

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF8
Parent code in ICD-10
C81-C96
Name in latin
Leuc(h)aemia monocytica

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 111 47 64
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 65.71 60.56 69.49

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
101
Matched controls
1011
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
396.6
60.3
55
*
C93.1
ICD-10 Finland
Chronic myelomonocytic leukaemia
+∞
46.5
41
*
C93.0
ICD-10 Finland
Acute monoblastic/monocytic leukaemia
+∞
36.7
33
*
XW000
NOMESCO Finland
Bone marrow biopsy
41.3
31.5
39
15
WW500
NOMESCO Finland
Blood transfusion
100.2
27.5
29
*
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
294.0
23.7
23
*
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
21.6
20
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
21.6
20
*
A04AA01
ATC
ondansetron; systemic, rectal
55.3
19.1
22
5
D64.9
ICD-10 Finland
Anaemia, unspecified
9.7
16.1
35
52
Z51.5
ICD-10 Finland
Palliative care
20.0
14.2
21
13
R50.9
ICD-10 Finland
Fever, unspecified
7.0
13.0
35
71
L03AA02
ATC
filgrastim; parenteral
+∞
12.8
12
*
M04AA01
ATC
allopurinol; systemic
6.3
12.0
35
78
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
134.7
11.7
12
*
C93.9
ICD-10 Finland
Monocytic leukaemia, unspecified
+∞
11.7
11
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
24.8
11.1
15
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.3
10.9
31
66
B03XA02
ATC
darbepoetin alfa; parenteral
122.2
10.6
11
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.8
10.0
30
68
L01XX05
ATC
hydroxycarbamide; oral
30.5
8.7
11
*
9860/3-C42.1
ICD-O-3
Myeloid leukemia, NOS, of bone marrow
+∞
8.4
8
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
8.4
8
*
9891/3-C42.1
ICD-O-3
Acute monocytic leukemia of bone marrow
+∞
8.4
8
*
JN4BD
NOMESCO Finland
Extensive body CT
10.8
8.1
15
16
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
86.1
7.5
8
*
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
86.1
7.5
8
*
J05AB11
ATC
valaciclovir; oral
4.9
7.5
25
63
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
7.4
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.4
7
*
A41.9
ICD-10 Finland
Sepsis, unspecified
9.1
6.6
13
16
A03FA01
ATC
metoclopramide; systemic, rectal
5.2
6.5
20
46
127
Kela drug reimbursment
Transplant complication
28.7
6.3
8
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
6.3
6
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
6.3
6
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
6.3
6
*
J01MA12
ATC
levofloxacin; systemic
3.5
6.3
31
112

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3042111) Morphology [Interpretation] in Bone marrow Narrative
32
17
26.04
42.10
3.5
2.8
—
—
—
0
0
(21494434) Karyotype in Bone marrow
28
13
28.47
38.69
1.5
1.2
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
27
19
18.46
30.73
6.0
1.8
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
22
11
24.70
29.16
1.5
1.6
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
37
59
8.91
24.03
17.7
4.2
%
1.2
0.8
0.51
30
19
(3021440) Promyelocytes/100 leukocytes in Blood
35
57
8.51
22.20
15.2
4.3
%
0.1
0.2
0.12
29
17
(3005719) IgG [Mass/volume] in Serum or Plasma
32
53
8.08
19.85
5.5
1.6
g/l
10.0
11.4
0.75
32
47
(3023520) Reticulocytes [#/volume] in Blood
41
90
6.64
19.43
12.6
2.9
e9/l
84.0
64.7
1.16
35
73
(3025159) Blasts/100 leukocytes in Blood
30
55
7.10
16.78
14.2
4.4
%
1.7
0.1
0.67
24
15
(3002179) Metamyelocytes/100 leukocytes in Blood
29
53
7.05
16.24
15.2
4.5
%
0.5
0.4
0.27
21
13
(4035726)
20
26
9.16
14.94
1.4
1.2
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
16
16
11.52
14.37
3.2
1.3
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
16
17
10.83
13.78
3.0
1.3
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
14
13
12.18
13.12
3.2
1.3
—
—
—
0
0
(3012095) Magnesium [Moles/volume] in Serum or Plasma
41
124
4.66
12.95
7.4
2.0
mmol/l
0.8
0.8
0.03
41
114
(3017143) Hepatitis C virus Ab [Presence] in Serum
27
67
5.00
10.70
1.7
1.4
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
21
42
5.93
10.53
1.5
1.3
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
25
59
5.18
10.48
3.0
1.1
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
12
13
10.23
10.06
1.8
1.2
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
14
8
19.76
9.68
18.0
4.5
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
55
244
3.49
9.59
11.4
3.8
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
12
14
9.49
9.53
1.8
1.1
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
14
21
7.48
9.13
1.4
1.3
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
70
376
3.33
8.67
20.5
5.2
%
2.1
2.9
1.12
70
347
(3019069) Monocytes/100 leukocytes in Blood
70
379
3.29
8.50
22.9
5.5
%
16.0
8.8
6.59
70
352
(42869858) Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method
8
0
+∞
8.43
1.0
0.0
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
14
23
6.82
8.40
1.6
1.3
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
68
364
3.24
8.38
21.1
5.1
%
0.6
0.6
0.02
68
332
(42870588) Differential panel, method unspecified - Blood
56
269
3.18
8.30
24.3
5.3
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
70
390
3.15
7.89
22.4
5.3
%
26.9
26.9
0.01
70
358
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
21
54
4.56
7.85
2.9
1.4
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
31
108
3.60
7.67
1.9
1.8
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
11
16
7.52
7.29
2.5
1.1
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
10
5
21.76
7.27
2.5
3.6
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
10
5
21.76
7.27
2.5
3.6
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
28
97
3.52
6.93
1.8
1.7
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
51
252
2.89
6.91
17.0
2.0
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
10
14
7.75
6.81
1.2
1.1
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
27
94
3.47
6.62
1.9
1.4
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
10
7
15.52
6.53
4.0
1.9
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
32
130
3.05
6.07
2.0
1.6
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
40
185
2.82
6.00
16.7
1.9
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
10
17
6.37
5.73
2.6
1.2
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
33
141
2.91
5.69
3.9
1.7
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
69
428
2.62
5.64
20.0
5.4
e9/l
0.1
0.2
2.61
64
375
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
14
34
4.57
5.54
3.4
1.1
—
—
—
0
0
(40757578) FLT3 gene targeted mutation analysis in Bone marrow by Molecular genetics method
5
0
+∞
5.24
1.0
0.0
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
9
9
10.75
5.13
1.7
1.0
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
25
97
3.04
5.07
2.8
1.7
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
18
57
3.58
5.02
1.7
1.5
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
34
157
2.68
5.01
21.4
4.6
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
32
144
2.72
4.95
3.1
1.2
g/l
4.0
2.7
0.70
26
79
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
25
99
2.97
4.88
2.7
1.8
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
61
376
2.38
4.79
25.6
3.6
—
—
—
0
0
(3018418) pH of Serum or Plasma
46
252
2.41
4.70
12.3
3.1
ph
7.4
7.4
—
8
41
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
8
8
10.65
4.60
1.3
1.4
—
—
—
0
0
(3000991) Gas panel - Venous blood
20
73
3.12
4.47
6.9
6.8
—
—
—
0
0
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
11
26
4.59
4.47
1.4
1.6
iu/ml
0.1
0.5
—
6
5
(3037756) Immunofixation for Serum or Plasma
9
12
8.05
4.45
1.3
1.2
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
24
99
2.82
4.34
4.2
3.9
kpa
5.7
5.9
0.34
24
94
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
7
6
12.33
4.33
4.3
2.3
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
7
6
12.33
4.33
1.9
1.2
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
7
6
12.33
4.33
2.1
1.2
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
18
64
3.16
4.19
1.3
2.1
g/l
0.2
0.2
0.01
18
53
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
65
429
2.24
4.15
16.4
5.0
mmol/l
1.2
1.2
1.11
58
365
(3012544) pH of Venous blood
24
102
2.73
4.09
4.3
4.0
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
7
7
10.56
4.07
5.1
1.3
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
7
7
10.56
4.07
5.1
1.3
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
7
7
10.56
4.07
5.1
1.3
—
—
—
0
0
(40758558) Short blood count panel - Blood
39
211
2.31
4.00
21.8
5.3
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
7
8
9.24
3.83
5.1
1.4
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
8
12
7.08
3.74
7.3
2.7
pg
33.8
34.3
—
8
12
(3025941) Bacteria identified in Stool by Culture
14
46
3.34
3.68
1.1
1.2
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
8
13
6.53
3.57
2.0
1.2
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
59
391
2.09
3.55
14.7
4.8
mmol/l
1.2
1.2
0.80
59
346
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
6
7
8.97
3.30
5.7
1.4
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
9
20
4.80
3.19
1.7
1.1
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
72
880
0.48
3.13
5.1
4.5
mmol/l
4.1
4.5
1.61
66
797
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
8
16
5.30
3.11
1.9
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
8
16
5.30
3.11
1.9
1.3
—
—
—
0
0
(44790049)
6
8
7.84
3.09
1.7
1.3
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
6
8
7.84
3.09
3.3
1.1
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
6
8
7.84
3.09
3.3
1.1
—
—
—
0
0
(44790047)
6
8
7.84
3.09
1.7
1.3
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
6
8
7.84
3.09
3.3
1.1
—
—
—
0
0
(44790048)
6
8
7.84
3.09
1.7
1.3
—
—
—
0
0
(44806118)
6
8
7.84
3.09
1.7
1.3
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
6
8
7.84
3.09
3.3
1.1
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
51
334
1.97
3.05
5.9
3.0
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
71
869
0.49
3.02
4.8
4.5
mmol/l
1.2
1.5
3.61
64
781
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
75
900
0.49
2.95
5.4
5.1
mmol/l
2.4
2.6
0.94
68
813
(3032080) INR in Blood by Coagulation assay
55
378
1.90
2.79
8.3
9.8
inr
1.4
1.3
0.39
18
109
(3044927) Protein electrophoresis panel - Urine
6
10
6.27
2.73
1.0
1.1
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
7
15
4.90
2.64
1.1
1.1
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
15
4.90
2.64
1.4
1.1
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
7
15
4.90
2.64
1.6
1.0
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
44
287
1.88
2.57
4.0
2.5
u/l
49.9
31.7
0.40
44
273
(3000012) Reticulocyte production index
5
7
7.41
2.57
3.8
2.1
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
5
7
7.41
2.57
1.4
1.1
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
9
26
3.67
2.54
8.4
1.2
g/l
0.2
0.2
—
9
26
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
69
839
0.53
2.53
4.9
4.1
mmol/l
1.5
1.3
1.29
63
747
(3003327) Ova and parasites identified in Stool by Light microscopy
8
21
4.02
2.51
1.9
1.4
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
21
105
2.23
2.51
3.0
1.2
titre
384.0
537.1
—
5
35
(3024354) Oxygen [Partial pressure] in Venous blood
17
78
2.39
2.46
3.0
3.1
kpa
4.0
4.4
0.64
17
73
(3002256) Pathology report gross observation
15
65
2.51
2.44
2.1
1.1
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
6
12
5.22
2.43
1.5
1.2
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
6
12
5.22
2.43
1.5
1.2
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
8
22
3.83
2.41
1.6
1.3
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
7
17
4.32
2.40
1.3
1.1
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
7
17
4.32
2.40
1.6
1.1
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
5
8
6.48
2.39
3.8
1.1
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
5
8
6.48
2.39
3.8
1.1
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
9
28
3.40
2.36
3.2
3.5
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
9
28
3.40
2.36
8.4
1.2
g/l
1.3
1.1
—
9
28
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
6
13
4.81
2.30
1.5
1.2
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
7
18
4.08
2.29
1.7
1.6
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
8
24
3.51
2.23
1.0
1.0
—
—
—
0
0
(40761535) Cells panel - Urine sediment
17
82
2.27
2.21
3.9
3.5
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
55
0.00
2.13
0.0
1.4
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
38
249
1.80
2.13
3.0
1.5
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
15
70
2.32
2.09
6.9
2.5
kpa
4.8
5.1
0.45
15
59
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
5
10
5.18
2.09
1.0
1.0
—
—
—
0
0
(4062490)
5
10
5.18
2.09
2.4
1.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
42
287
1.75
2.03
4.0
3.1
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
6
16
3.90
1.96
14.7
2.9
%
52.0
64.8
—
6
16
(3021788) Differential panel - Synovial fluid
6
16
3.90
1.96
1.3
1.6
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
5
11
4.70
1.96
1.8
1.5
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
11
4.70
1.96
1.0
1.3
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
9
34
2.79
1.91
6.7
1.8
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
17
88
2.10
1.87
6.4
3.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
33
216
1.75
1.83
2.2
1.4
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
7
23
3.18
1.83
1.7
1.2
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
24
144
1.85
1.76
4.9
2.8
e6/l
0.8
2.4
0.91
17
84
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
6
19
3.28
1.68
1.2
1.2
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
14
3.69
1.63
1.2
1.1
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
25
157
1.76
1.58
4.5
2.5
e6/l
1.3
1.2
0.05
18
97
(3023323) Follitropin [Units/volume] in Serum or Plasma
5
15
3.44
1.54
3.6
1.1
iu/l
21.8
17.3
—
5
15
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
26
167
1.73
1.52
1.2
1.3
u/ml
1.1
1.5
—
9
48
(3020891) Body temperature
9
38
2.49
1.49
3.7
4.2
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
9
39
2.42
1.47
4.4
7.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
11
53
2.19
1.44
1.8
1.6
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
6
23
2.70
1.38
1.0
1.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
11
54
2.15
1.38
3.0
1.7
—
—
—
0
0
(3009445) Proteinase 3 Ab [Units/volume] in Serum
9
42
2.24
1.37
1.1
1.1
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
5
17
3.03
1.37
1.8
1.2
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
85
938
0.60
1.37
52.1
15.3
umol/l
92.7
81.7
1.68
85
938
(3018095) Leukocytes [#/volume] in Urine
44
332
1.54
1.35
7.4
3.3
e6/l
144.2
85.0
0.32
36
250
(3022313) Gas panel - Capillary blood
10
48
2.19
1.32
8.8
2.7
—
—
—
0
0
(3015736) pH of Urine
43
325
1.53
1.30
5.4
3.8
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
14
78
1.91
1.28
6.5
5.2
mmol/l
1.3
1.4
0.14
14
71
(1761868) Lipid panel - Serum or Plasma
17
263
0.58
1.22
3.2
3.3
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
18
111
1.74
1.21
5.8
5.6
kpa
11.1
10.9
0.08
18
104
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
18
111
1.74
1.21
5.8
5.6
kpa
4.9
5.2
0.60
18
104
(3002582) Erythrocytes [#/volume] in Urine
39
293
1.51
1.20
6.5
2.9
e6/l
38.0
276.5
0.58
33
234
(3051387) C reactive protein [Mass/volume] in Capillary blood
5
20
2.57
1.16
4.6
5.6
mg/l
50.0
34.3
—
5
14
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
10
51
2.06
1.15
7.1
7.0
%
0.9
0.7
—
10
51
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
7
30
2.42
1.14
3.3
1.7
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
12
66
1.92
1.14
6.7
3.2
—
—
—
0
0
(3022145) Colonoscopy Study observation
13
74
1.86
1.12
1.6
1.2
—
—
—
0
0
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
5
21
2.44
1.10
1.0
2.1
u/ml
13.0
17.9
—
5
14
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
10
52
2.01
1.10
7.1
7.0
%
1.8
1.6
—
10
52
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
74
830
0.67
1.09
6.5
6.4
mmol/mol
40.8
41.0
0.06
67
755
(3035350) Ketones [Presence] in Urine by Test strip
52
421
1.44
1.08
6.3
3.7
estimate
0.0
0.0
0.00
11
72
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
79
874
0.67
1.07
5.8
4.8
mmol/l
6.4
6.1
0.61
74
776
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
9
46
2.04
1.06
1.9
2.4
%
0.7
0.6
—
9
46
(3030467) Casts [#/volume] in Urine by Automated count
36
273
1.47
1.05
5.1
2.7
e6/l
0.8
0.4
0.53
31
210
(3009261) Glucose [Presence] in Urine by Test strip
53
433
1.43
1.04
6.1
3.7
estimate
0.0
0.0
0.00
12
69
(3006184) Hemoglobin [Mass/volume] in Capillary blood
5
22
2.33
1.04
1.2
1.6
g/l
116.0
131.3
—
5
11
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
9
49
1.91
1.01
1.9
2.3
%
2.0
1.1
—
9
49
(40761511) CBC panel - Blood by Automated count
83
907
0.66
1.01
36.3
12.8
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
70
604
1.43
1.00
7.5
4.0
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
52
426
1.42
1.00
7.5
5.0
estimate
0.0
0.0
0.00
12
70
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
47
383
1.39
0.91
3.9
3.9
ng/l
37.5
50.3
0.37
35
288
(3049717) Cytology report of Urine Cyto stain
6
29
2.13
0.91
1.7
1.7
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
27
199
1.47
0.90
4.6
3.6
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
33
254
1.43
0.88
5.2
2.6
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
31
237
1.43
0.85
8.0
4.0
estimate
0.0
0.0
—
9
69
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
6
33
1.86
0.80
1.0
1.1
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
5
25
2.05
0.73
2.2
1.8
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
15
102
1.54
0.72
3.0
1.5
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
76
827
0.74
0.69
38.2
12.4
ml/min/173m2
69.2
76.0
1.30
66
664
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
40
331
1.33
0.67
7.1
4.1
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
16
113
1.49
0.65
6.1
5.6
mmol/l
1.8
1.7
0.03
11
94
(3041096) Erythrocytes [Presence] in Urine by Automated
29
230
1.35
0.64
6.6
3.5
—
—
—
0
0
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
8
49
1.68
0.64
10.1
6.9
mmol/l
22.9
25.3
—
8
42
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
5
30
1.70
0.62
1.2
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
5
30
1.70
0.62
1.2
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
5
30
1.70
0.62
1.2
1.2
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
47
402
1.29
0.62
2.9
2.0
pmol/l
83.9
92.3
0.72
30
208
(3028626) Oxygen [Partial pressure] in Capillary blood
6
35
1.75
0.59
2.0
2.2
kpa
7.7
7.9
—
6
28
(3004716) Salmonella sp identified in Stool by Organism specific culture
6
38
1.61
0.55
1.5
1.3
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
71
648
1.27
0.52
5.5
3.8
pmol/l
14.8
14.9
0.08
66
579
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
6
40
1.53
0.52
1.8
1.5
ug/l
194.7
195.6
—
6
35
(3003338) MCHC [Mass/volume]
68
737
0.80
0.49
60.0
17.8
g/l
328.2
332.2
2.49
68
731
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
19
0.00
0.39
0.0
1.5
—
1.3
—
0
13
(3000492) Spirometry study
5
78
0.62
0.37
1.2
1.3
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
16
130
1.27
0.31
1.4
1.5
—
—
—
0
0
(3019060) Gas panel - Arterial blood
10
77
1.33
0.27
2.5
3.8
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
7
91
0.75
0.23
1.3
1.7
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.5
—
8.8
—
0
11
(4268621)
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
13
0.00
0.21
0.0
2.3
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
0
14
0.00
0.20
0.0
1.2
—
7.2
—
0
5
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
33
301
1.14
0.20
4.0
3.9
%
25.9
24.7
0.13
17
140
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
15
128
1.20
0.19
1.4
1.3
u/ml
1.2
16.5
—
5
40
(4010399)
5
67
0.73
0.17
1.4
1.3
—
—
—
0
0
(3019225) pH of Specimen
10
83
1.23
0.16
15.0
2.7
—
—
—
0
0
(3013512) EKG study
30
279
1.10
0.13
5.0
4.1
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
10
87
1.16
0.10
2.5
1.8
%
1.6
1.7
—
10
76
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
48
461
1.07
0.09
3.4
2.9
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
76
777
0.93
0.09
41.2
14.8
%
33.7
39.6
2.89
44
527
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
6
56
1.08
0.09
1.5
1.2
—
28.1
—
0
6
(36660697) Celiac disease serology panel - Serum
6
57
1.06
0.08
1.2
1.3
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
6
71
0.84
0.08
3.2
2.1
nmol/l
8.7
15.6
—
6
61
(3022621) pH of Urine by Test strip
6
73
0.81
0.08
4.2
2.3
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
10
90
1.12
0.05
2.0
1.3
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
72
710
1.04
0.03
57.2
16.8
%
15.3
13.8
5.27
72
687
(3044889) 12 lead EKG panel
64
633
1.03
0.01
5.0
4.0
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
11
107
1.03
0.00
10.7
7.8
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
12
123
0.97
0.00
1.4
1.2
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
32
324
0.98
0.00
5.1
3.8
mg/mmol
35.6
9.3
1.01
25
198
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
87
874
0.98
0.00
50.0
13.3
mg/l
30.2
23.7
1.18
80
679
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
11.7
—
0
5
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014271) Vancomycin [Susceptibility]
0
8
0.00
0.00
0.0
2.6
—
—
—
0
0
(44806420)
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012565) Volume of 24 hour Urine
0
5
0.00
0.00
0.0
2.4
—
2770.0
—
0
5
(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
14.5
—
0
5
(3005082) Progesterone [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
29.2
—
0
5
(3051651) Icteric interference index of Serum or Plasma
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.4
—
75.9
—
0
9
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: CD2_MONOCYTIC_LEUKAEMIA_EXALLC – Monocytic leukaemia

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).