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Monocytic leukaemia

CD2_MONOCYTIC_LEUKAEMIA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C93
  • Hospital discharge: ICD-9 206
  • Hospital discharge: ICD-8 206
  • Cause of death: ICD-10 C93
  • Cause of death: ICD-9 206
  • Cause of death: ICD-8 206

2 out of 7 registries used, show all original rules.

111

4. Check minimum number of events

None

111

5. Include endpoints

None

111

6. Filter based on genotype QC (FinnGen only)

111

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF8
Parent code in ICD-10
C81-C96
Name in latin
Leuc(h)aemia monocytica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 111 47 64
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 65.71 60.56 69.49

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
101
Matched controls
1008
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C93.1
ICD-10 Finland
Chronic myelomonocytic leukaemia
+∞
46.5
41
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
53.0
46.1
55
22
C93.0
ICD-10 Finland
Acute monoblastic/monocytic leukaemia
+∞
36.7
33
*
XW000
NOMESCO Finland
Bone marrow biopsy
44.3
32.0
39
14
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
+∞
25.0
23
*
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
21.6
20
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
246.1
20.3
20
*
WW500
NOMESCO Finland
Blood transfusion
22.0
19.8
29
18
D64.9
ICD-10 Finland
Anaemia, unspecified
7.2
13.2
35
69
R50.9
ICD-10 Finland
Fever, unspecified
6.3
12.0
35
78
C93.9
ICD-10 Finland
Monocytic leukaemia, unspecified
+∞
11.7
11
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.9
11.4
30
58
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.0
10.5
31
69
A04AA01
ATC
ondansetron; systemic, rectal
7.5
9.3
22
36
Z51.5
ICD-10 Finland
Palliative care
7.7
9.1
21
33
M04AA01
ATC
allopurinol; systemic
4.6
9.1
35
104
L01XX05
ATC
hydroxycarbamide; oral
30.5
8.7
11
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
12.3
8.6
15
14
9891/3-C42.1
ICD-O-3
Acute monocytic leukemia of bone marrow
+∞
8.4
8
*
9860/3-C42.1
ICD-O-3
Myeloid leukemia, NOS, of bone marrow
+∞
8.4
8
*
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
+∞
8.4
8
*
L03AA02
ATC
filgrastim; parenteral
19.2
8.3
12
7
J05AB11
ATC
valaciclovir; oral
4.6
7.1
25
67
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
74.3
6.5
7
*
A41.9
ICD-10 Finland
Sepsis, unspecified
8.6
6.3
13
17
A05AA02
ATC
ursodeoxycholic acid; oral
28.6
6.3
8
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
28.6
6.3
8
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
6.3
6
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
6.3
6
*
B03XA02
ATC
darbepoetin alfa; parenteral
11.0
6.2
11
11
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
8.9
6.0
12
15

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(21494434) Karyotype in Bone marrow
28
14
26.41
37.55
1.5
1.3
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
32
24
18.33
35.50
3.5
1.8
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
22
13
20.86
27.07
1.5
1.7
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
27
32
10.83
22.00
6.0
2.1
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
41
92
6.48
18.95
12.6
3.5
e9/l
84.0
71.5
0.62
35
71
(3017181) Myelocytes/100 leukocytes in Blood
37
82
6.27
17.17
17.7
4.1
%
1.2
1.0
0.29
30
34
(3021440) Promyelocytes/100 leukocytes in Blood
35
76
6.27
16.54
15.2
4.2
%
0.1
0.2
0.22
29
30
(3005719) IgG [Mass/volume] in Serum or Plasma
32
77
5.43
13.32
5.5
2.3
g/l
10.0
9.7
0.13
32
68
(3025159) Blasts/100 leukocytes in Blood
30
70
5.50
12.90
14.2
4.5
%
1.7
0.0
0.71
24
25
(3002179) Metamyelocytes/100 leukocytes in Blood
29
69
5.34
12.15
15.2
3.9
%
0.5
0.4
0.31
21
18
(3012095) Magnesium [Moles/volume] in Serum or Plasma
41
153
3.66
9.32
7.4
3.5
mmol/l
0.8
0.8
0.05
41
141
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
14
21
7.48
9.13
3.2
2.0
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
14
21
7.48
9.13
18.0
5.0
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
16
29
6.28
8.78
3.2
1.8
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
16
30
6.06
8.49
3.0
1.8
—
—
—
0
0
(42869858) Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method
8
0
+∞
8.43
1.0
0.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
25
71
4.25
8.27
3.0
2.0
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
27
83
3.98
8.02
1.7
1.5
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
10
12
9.06
7.70
1.2
1.5
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
21
55
4.48
7.67
1.5
1.4
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
14
29
5.38
6.65
1.4
1.4
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
70
417
2.84
6.54
20.5
5.9
%
2.1
2.5
0.55
70
382
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
10
7
15.52
6.53
4.0
2.7
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
12
22
5.99
6.44
1.8
1.4
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
70
421
2.79
6.35
22.9
6.2
%
16.0
8.6
6.89
70
387
(3022096) Basophils/100 leukocytes in Blood
68
403
2.77
6.35
21.1
5.9
%
0.6
0.6
0.08
68
365
(42870588) Differential panel, method unspecified - Blood
56
301
2.74
6.34
24.3
5.9
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
55
298
2.68
6.06
11.4
4.3
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
14
32
4.86
5.96
1.6
1.4
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
10
9
12.06
5.92
2.5
2.7
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
10
9
12.06
5.92
2.5
2.7
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
12
24
5.48
5.89
1.8
1.4
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
70
434
2.66
5.77
22.4
6.1
%
26.9
26.8
0.02
70
394
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
13
30
4.78
5.46
3.0
2.0
%
175.7
199.6
0.47
13
30
(46235355) HIV 1 and 2 tests - Meaningful Use set
31
132
2.87
5.35
1.9
1.8
—
—
—
0
0
(40757578) FLT3 gene targeted mutation analysis in Bone marrow by Molecular genetics method
5
0
+∞
5.24
1.0
0.0
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
28
115
2.92
5.15
1.8
1.7
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
10
19
5.69
5.14
2.6
1.8
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
9
9
10.75
5.13
1.7
1.2
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
21
73
3.31
5.10
2.9
1.6
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
27
111
2.89
4.94
1.9
1.5
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
32
148
2.63
4.67
2.0
1.8
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
11
26
4.59
4.47
2.5
3.3
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
9
12
8.05
4.45
17.9
5.3
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
8
9
9.46
4.35
2.1
2.9
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
69
461
2.31
4.35
20.0
6.3
e9/l
0.1
0.2
1.79
64
404
(3012544) pH of Venous blood
24
99
2.82
4.34
4.3
5.4
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
24
102
2.73
4.09
4.2
5.3
kpa
5.7
5.8
0.17
24
97
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
11
28
4.25
4.08
1.4
1.5
iu/ml
0.1
0.0
—
6
5
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
14
43
3.58
4.06
3.4
1.4
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
33
166
2.41
3.99
3.9
2.0
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
40
220
2.28
3.94
16.7
2.4
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
51
311
2.18
3.90
17.0
2.5
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
18
67
3.01
3.88
1.7
1.4
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
7
8
9.24
3.83
2.1
1.3
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
7
9
8.20
3.61
4.3
2.3
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
32
166
2.30
3.57
3.1
1.5
g/l
4.0
2.9
0.52
26
101
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
8
13
6.53
3.57
7.3
1.8
pg
33.8
33.8
—
8
13
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
8
13
6.53
3.57
1.3
1.7
—
—
—
0
0
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
6
6
10.47
3.54
5.7
2.2
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
6
6
10.47
3.54
5.7
2.3
—
—
—
0
0
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
6
6
10.47
3.54
5.7
2.2
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
6
6
10.47
3.54
5.7
2.3
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
6
6
10.47
3.54
5.7
2.3
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
6
6
10.47
3.54
5.7
2.3
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
6
6
10.47
3.54
5.7
2.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
34
183
2.24
3.47
21.4
6.1
—
—
—
0
0
(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis
12
37
3.52
3.45
3.8
1.5
g/l
0.1
0.2
0.28
12
31
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
25
118
2.44
3.43
2.8
1.8
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
7
10
7.38
3.41
1.9
1.1
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
9
20
4.80
3.19
1.3
1.1
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
25
122
2.35
3.18
2.7
1.9
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
6
8
7.84
3.09
1.3
1.6
—
—
—
0
0
(3013727) Leukocytes other/100 leukocytes in Blood
6
8
7.84
3.09
14.5
6.6
%
45.5
44.3
—
6
8
(4035726)
20
89
2.52
3.09
1.4
1.3
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
7
12
6.14
3.07
5.1
2.3
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
7
12
6.14
3.07
1.6
1.0
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
7
12
6.14
3.07
5.1
2.3
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
7
12
6.14
3.07
5.1
2.3
—
—
—
0
0
(3000991) Gas panel - Venous blood
20
90
2.49
3.02
6.8
6.6
—
—
—
0
0
(3008536) Aspergillus sp Ab [Presence] in Serum
5
5
10.38
3.00
3.8
1.2
—
—
—
0
0
(3018418) pH of Serum or Plasma
46
293
1.97
2.96
12.3
4.1
ph
7.4
7.4
—
8
59
(3044927) Protein electrophoresis panel - Urine
6
9
6.97
2.90
1.0
1.1
—
—
—
0
0
(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis
11
36
3.28
2.90
4.0
1.4
g/l
34.9
36.8
0.41
11
30
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
61
433
1.91
2.81
25.6
4.4
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
5
6
8.65
2.77
1.4
1.3
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
7
14
5.26
2.77
1.3
1.0
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
7
14
5.26
2.77
1.7
1.3
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
14
55
2.77
2.74
1.1
1.3
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
8
19
4.45
2.73
2.0
1.3
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
6
10
6.27
2.73
3.3
2.3
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
6
10
6.27
2.73
3.3
2.3
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
6
10
6.27
2.73
3.3
2.3
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
6
10
6.27
2.73
3.3
2.3
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
7
15
4.90
2.64
5.1
2.1
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
65
478
1.87
2.61
16.4
6.9
mmol/l
1.2
1.2
0.82
58
395
(3000012) Reticulocyte production index
5
7
7.41
2.57
3.8
1.4
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
71
857
0.52
2.57
4.8
4.6
mmol/l
1.2
1.4
3.31
64
759
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
7
16
4.59
2.52
1.7
1.3
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
7
16
4.59
2.52
1.6
1.0
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
8
21
4.02
2.51
1.9
1.4
—
—
—
0
0
(40758558) Short blood count panel - Blood
39
247
1.89
2.48
21.8
7.1
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
72
863
0.53
2.48
5.1
4.6
mmol/l
4.1
4.4
1.54
66
773
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
9
27
3.53
2.45
8.4
1.3
g/l
0.2
0.2
—
9
27
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
75
887
0.52
2.44
5.4
5.1
mmol/l
2.4
2.6
0.84
68
787
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
7
17
4.32
2.40
1.1
1.1
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
59
429
1.80
2.39
14.7
6.1
mmol/l
1.2
1.2
0.50
59
381
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
18
87
2.28
2.32
1.3
2.6
g/l
0.2
0.2
0.03
18
77
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
9
29
3.28
2.28
8.4
1.3
g/l
1.3
1.2
—
9
29
(3048929) Epstein Barr virus Ab [Presence] in Serum
9
29
3.28
2.28
1.7
1.3
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
51
359
1.78
2.28
5.9
3.2
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
69
830
0.55
2.24
4.9
4.2
mmol/l
1.5
1.3
1.25
63
731
(3044941) Cell count panel - Synovial fluid
5
9
5.75
2.23
1.8
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
8
24
3.51
2.23
1.9
1.4
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
8
24
3.51
2.23
1.9
1.4
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
21
111
2.10
2.19
3.0
1.2
titre
384.0
535.2
—
5
29
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
6
14
4.46
2.18
5.7
2.2
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
17
83
2.24
2.15
3.0
5.1
kpa
4.0
4.3
0.39
17
78
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
5
10
5.18
2.09
1.0
1.1
—
—
—
0
0
(40761535) Cells panel - Urine sediment
17
85
2.18
2.03
3.9
4.2
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
44
305
1.73
2.02
4.0
3.1
u/l
49.9
32.9
0.36
44
291
(44790048)
6
16
3.90
1.96
1.7
1.8
—
—
—
0
0
(44806118)
6
16
3.90
1.96
1.7
1.8
—
—
—
0
0
(44790049)
6
16
3.90
1.96
1.7
1.8
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
6
16
3.90
1.96
1.5
1.9
—
—
—
0
0
(44790047)
6
16
3.90
1.96
1.7
1.8
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
5
11
4.70
1.96
3.8
2.2
—
—
—
0
0
(4062490)
5
11
4.70
1.96
2.4
1.3
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
5
11
4.70
1.96
3.8
2.2
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
53
0.00
1.93
0.0
1.4
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
6
17
3.67
1.86
14.7
2.2
%
52.0
62.6
—
6
17
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
9
35
2.71
1.85
6.7
2.1
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
23
3.18
1.83
1.4
1.8
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
8
29
2.89
1.83
1.0
1.1
—
—
—
0
0
(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood
9
36
2.63
1.78
3.8
6.0
%
1.3
1.6
—
9
31
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
15
76
2.13
1.74
6.9
3.0
kpa
4.8
5.0
0.32
15
68
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
6
19
3.28
1.68
1.5
1.7
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
55
420
1.61
1.68
8.3
9.7
inr
1.4
1.3
0.53
18
124
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
10
43
2.46
1.65
9.2
3.8
mmol/l
24.4
25.7
—
10
43
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
24
147
1.81
1.65
4.9
3.0
e6/l
0.8
1.9
0.62
17
91
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
8
32
2.61
1.63
1.6
1.4
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
6
20
3.11
1.60
1.5
1.8
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
33
225
1.66
1.56
2.2
1.4
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
6
21
2.96
1.52
1.2
1.1
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
25
160
1.73
1.48
4.5
2.8
e6/l
1.3
0.8
0.21
18
102
(3026008) Bacteria identified in Urine by Culture
42
308
1.58
1.48
4.0
3.1
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
9
40
2.36
1.44
3.2
2.9
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
11
54
2.15
1.38
1.8
1.6
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
26
172
1.67
1.37
1.2
1.3
u/ml
1.1
1.4
—
9
51
(3020564) Creatinine [Moles/volume] in Serum or Plasma
85
937
0.60
1.34
52.1
19.7
umol/l
92.7
81.9
1.65
85
937
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
9
43
2.19
1.34
1.9
6.4
%
0.7
0.7
—
9
43
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
11
55
2.11
1.32
3.0
1.7
—
—
—
0
0
(3020891) Body temperature
9
44
2.14
1.30
3.7
4.8
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
18
2.86
1.30
1.0
1.5
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
17
266
0.57
1.28
3.2
3.3
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
6
25
2.48
1.26
1.0
1.1
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
17
103
1.77
1.21
6.4
3.7
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
83
911
0.65
1.10
36.3
16.0
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
21
2.44
1.10
1.2
1.9
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
7
33
2.19
1.07
3.3
1.8
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
11
60
1.93
1.07
7.5
3.5
e6/l
0.0
0.1
1.77
11
60
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
9
47
1.99
1.05
1.9
6.0
%
2.0
1.2
—
9
47
(3022313) Gas panel - Capillary blood
10
53
1.97
1.05
8.8
3.2
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
44
347
1.44
1.05
7.4
3.6
e6/l
144.2
50.0
0.60
36
266
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
74
827
0.68
1.03
6.5
6.3
mmol/mol
40.8
40.9
0.02
67
754
(3030467) Casts [#/volume] in Urine by Automated count
36
280
1.42
0.91
5.1
3.0
e6/l
0.8
0.4
0.51
31
223
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
6
29
2.13
0.91
1.0
1.0
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
39
308
1.41
0.90
6.5
3.2
e6/l
38.0
249.5
0.54
33
250
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
76
838
0.70
0.88
38.2
16.1
ml/min/173m2
69.2
76.3
1.39
66
680
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
79
865
0.70
0.88
5.8
5.0
mmol/l
6.4
6.1
0.70
74
768
(3009261) Glucose [Presence] in Urine by Test strip
53
445
1.37
0.84
6.1
4.1
estimate
0.0
0.0
0.00
12
77
(3021601) Nitrite [Presence] in Urine by Test strip
52
436
1.36
0.83
7.5
5.4
estimate
0.0
0.0
0.00
12
83
(3011397) Hemoglobin [Presence] in Urine by Test strip
27
202
1.44
0.83
4.6
4.0
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
52
437
1.36
0.82
6.3
4.1
estimate
0.0
0.0
0.00
11
86
(40768800) Prostate Pathology biopsy report
0
27
0.00
0.78
0.0
1.2
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
47
391
1.35
0.78
3.9
4.5
ng/l
37.5
50.5
0.35
35
295
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
9
54
1.72
0.77
4.4
6.9
—
—
—
0
0
(3051387) C reactive protein [Mass/volume] in Capillary blood
5
24
2.13
0.75
4.6
5.8
mg/l
50.0
36.1
—
5
17
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
47
393
1.34
0.75
2.9
2.0
pmol/l
83.9
91.8
0.65
30
200
(3024891) Influenza virus A+B Ag [Presence] in Specimen
5
25
2.05
0.73
1.8
1.3
—
—
—
0
0
(3006184) Hemoglobin [Mass/volume] in Capillary blood
5
26
1.97
0.71
1.2
2.2
g/l
116.0
125.1
—
5
15
(3021901) Oxygen saturation in Capillary blood
5
27
1.89
0.69
2.2
2.1
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
12
79
1.58
0.66
6.7
4.1
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
14
97
1.51
0.62
6.5
7.0
mmol/l
1.3
1.3
0.05
14
91
(3022145) Colonoscopy Study observation
13
89
1.52
0.61
1.6
1.3
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
33
271
1.31
0.58
5.2
2.9
—
—
—
0
0
(3028626) Oxygen [Partial pressure] in Capillary blood
6
36
1.70
0.57
2.0
2.6
kpa
7.7
8.1
—
6
30
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
6
37
1.66
0.56
6.3
3.9
mg/l
1.4
1.6
—
6
32
(3049717) Cytology report of Urine Cyto stain
6
37
1.66
0.56
1.7
3.0
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
70
635
1.28
0.56
7.5
4.3
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
6
40
1.53
0.52
1.5
1.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
31
258
1.28
0.49
8.0
4.5
estimate
0.0
0.0
—
9
77
(3027801) Oxygen [Partial pressure] in Arterial blood
18
141
1.33
0.43
5.8
5.6
kpa
11.1
11.4
0.10
18
133
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
18
141
1.33
0.43
5.8
5.7
kpa
4.9
5.0
0.18
18
132
(42529406) Shigella sp [Presence] in Stool by Culture
5
31
1.64
0.43
1.2
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
5
31
1.64
0.43
1.2
1.2
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
5
31
1.64
0.43
1.2
1.2
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
16
123
1.35
0.43
5.9
6.2
%
95.5
95.5
0.02
16
118
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
0
15
0.00
0.41
0.0
1.1
—
7.0
—
0
5
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
40
350
1.22
0.41
7.1
4.5
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
71
659
1.21
0.40
5.5
3.8
pmol/l
14.8
14.9
0.13
66
581
(3002256) Pathology report gross observation
15
117
1.33
0.37
2.1
1.2
—
—
—
0
0
(3000492) Spirometry study
5
76
0.64
0.37
1.2
1.5
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
6
43
1.42
0.35
15.0
3.6
pmol/l
4.6
4.4
—
6
38
(3041096) Erythrocytes [Presence] in Urine by Automated
29
251
1.21
0.33
6.6
3.8
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
15
120
1.29
0.32
3.0
1.5
—
—
—
0
0
(4010399)
5
75
0.65
0.26
1.4
1.4
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
15
126
1.22
0.22
1.4
1.3
u/ml
1.2
13.5
—
5
44
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
16
136
1.21
0.21
1.4
1.5
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
(4268621)
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3019977) pH of Arterial blood
0
12
0.00
0.21
0.0
8.0
—
7.4
—
0
5
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
3.7
—
3.9
—
0
12
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.8
—
15.8
—
0
13
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
13
0.00
0.21
0.0
1.5
—
4.6
—
0
7
(3051611) Lipemic interference index of Serum or Plasma
0
13
0.00
0.21
0.0
2.6
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
6
75
0.79
0.16
3.2
2.2
nmol/l
8.7
14.3
—
6
68
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
7
85
0.81
0.15
1.3
1.7
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
48
456
1.09
0.13
3.4
3.0
—
—
—
0
0
(3019225) pH of Specimen
10
85
1.19
0.13
15.0
3.6
—
—
—
0
0
(3019060) Gas panel - Arterial blood
10
85
1.19
0.13
2.5
3.5
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
16
143
1.14
0.12
6.1
5.7
mmol/l
1.8
1.2
0.19
11
116
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
5
48
1.04
0.09
1.0
3.7
u/ml
13.0
230.6
—
5
41
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
87
886
0.92
0.09
50.0
17.0
mg/l
30.2
25.7
0.69
80
721
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
33
313
1.08
0.09
4.0
5.2
%
25.9
21.0
0.73
17
152
(40768804) Tissue Pathology biopsy report
38
363
1.07
0.08
3.0
2.1
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
6
58
1.04
0.08
1.2
1.2
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
6
58
1.04
0.08
1.5
1.2
—
34.7
—
0
5
(3022621) pH of Urine by Test strip
6
72
0.82
0.08
4.2
2.3
—
—
—
0
0
(3044889) 12 lead EKG panel
64
625
1.06
0.06
5.0
4.3
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
32
307
1.06
0.06
5.1
3.8
mg/mmol
35.6
8.8
1.04
25
189
(3013512) EKG study
30
288
1.06
0.05
5.0
4.3
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
10
92
1.10
0.03
2.5
1.7
%
1.6
1.6
—
10
77
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
10
93
1.08
0.02
2.0
1.3
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
11
116
0.94
0.01
10.7
8.7
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
12
122
0.98
0.00
1.4
1.4
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
76
757
1.01
0.00
41.2
18.0
%
33.7
39.2
2.59
44
510
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.8
—
11.2
—
0
6
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
7
0.00
0.00
0.0
3.6
—
—
—
0
0
(3026470) Cobalt [Mass/volume] in Blood
0
8
0.00
0.00
0.0
2.1
—
3.2
—
0
8
(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
100.0
—
0
5
(3037692) Legionella sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043410) Blood group antigens tested for on Red Blood Cells
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
7
0.00
0.00
0.0
3.6
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3014271) Vancomycin [Susceptibility]
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
72
720
1.00
0.00
57.2
21.4
%
15.3
14.0
4.07
72
701
(3004451) EKG impression Narrative
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.6
—
72.8
—
0
5
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014891) Appearance of Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
13.8
—
0
7
(3005082) Progesterone [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
29.2
—
0
5
(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
96.6
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_MONOCYTIC_LEUKAEMIA – Monocytic leukaemia

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).