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This is a non-core endpoint: only basic statistics are computed.

Carcinoma in situ of respiratory system, other/unspecified

CD2_INSITU_RESPNOS_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D02.3&, D02.4&
  • Hospital discharge: ICD-9 231[8-9]
  • Cause of death: ICD-10 D02.3&, D02.4&
  • Cause of death: ICD-9 231[8-9]

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 19 6 13
Unadjusted period prevalence (%) 0.00 0.00 0.01
Median age at first event (years) 70.17 71.96 69.34

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3000494) Fungus identified in Specimen by Culture
5
9
7.06
2.37
1.4
1.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
6
21
3.68
1.66
2.2
1.7
—
—
—
0
0
(3013512) EKG study
7
38
2.32
0.86
4.7
3.5
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
0
20
0.00
0.64
0.0
1.6
—
23.8
—
0
20
(3015736) pH of Urine
6
36
1.97
0.64
5.2
2.7
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
6
37
1.90
0.63
5.0
3.4
—
—
—
0
0
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
0
15
0.00
0.43
0.0
5.1
—
5.4
—
0
15
(3027801) Oxygen [Partial pressure] in Arterial blood
0
15
0.00
0.43
0.0
5.1
—
10.2
—
0
15
(3044889) 12 lead EKG panel
5
69
0.63
0.34
4.0
3.6
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
6
47
1.40
0.24
3.7
3.3
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
6
47
1.40
0.24
5.2
3.1
—
0.0
—
0
8
(3021601) Nitrite [Presence] in Urine by Test strip
6
49
1.33
0.23
6.2
3.9
—
0.0
—
0
9
(3009261) Glucose [Presence] in Urine by Test strip
6
50
1.29
0.22
5.2
3.2
—
0.0
—
0
5
(3020630) Protein [Mass/volume] in Serum or Plasma
0
11
0.00
0.22
0.0
1.9
—
68.6
—
0
11
(3004588) Protein electrophoresis panel - Serum or Plasma
0
11
0.00
0.22
0.0
1.4
—
—
—
0
0
(3019060) Gas panel - Arterial blood
0
10
0.00
0.22
0.0
1.6
—
—
—
0
0
(3002173) Hemoglobin [Mass/volume] in Arterial blood
0
12
0.00
0.22
0.0
6.0
—
123.2
—
0
12
(3016502) Oxygen saturation in Arterial blood
0
12
0.00
0.22
0.0
6.0
—
95.1
—
0
12
(3014576) Chloride [Moles/volume] in Serum or Plasma
0
12
0.00
0.22
0.0
6.9
—
103.0
—
0
12
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
9
102
0.78
0.20
23.6
17.1
umol/l
78.9
86.1
—
9
102
(3026008) Bacteria identified in Urine by Culture
5
42
1.26
0.11
1.4
2.5
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
8
71
1.22
0.09
3.8
4.1
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
6
67
0.85
0.09
3.8
3.8
mmol/l
7.7
6.9
—
6
61
(40761511) CBC panel - Blood by Automated count
9
100
0.81
0.09
16.0
15.5
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
7
0.00
0.00
0.0
1.0
—
10.4
—
0
7
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
9.9
—
384.1
—
0
7
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
0
6
0.00
0.00
0.0
1.3
—
1.2
—
0
6
(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
1.0
—
0.0
—
0
5
(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis
0
6
0.00
0.00
0.0
1.0
—
0.0
—
0
6
(4034850)
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3000991) Gas panel - Venous blood
0
6
0.00
0.00
0.0
10.0
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
0
8
0.00
0.00
0.0
1.3
—
249.6
—
0
8
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.8
—
24.2
—
0
6
(36660697) Celiac disease serology panel - Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
0
8
0.00
0.00
0.0
7.7
—
93.1
—
0
8
(3043409) Potassium [Moles/volume] in Arterial blood
0
5
0.00
0.00
0.0
1.4
—
3.7
—
0
5
(3020891) Body temperature
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(4010399)
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.4
—
828.4
—
0
5
(3008152) Bicarbonate [Moles/volume] in Arterial blood
0
9
0.00
0.00
0.0
2.3
—
25.3
—
0
9
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
8
78
1.04
0.00
13.8
4.5
u/l
80.6
83.6
—
8
72
(3022621) pH of Urine by Test strip
0
8
0.00
0.00
0.0
2.5
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
0
8
0.00
0.00
0.0
7.6
—
0.9
—
0
8
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
1.0
—
0.0
—
0
5
(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis
0
6
0.00
0.00
0.0
1.0
—
0.2
—
0
6
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
0
8
0.00
0.00
0.0
7.8
—
1.5
—
0
8

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_RESPNOS_EXALLC – Carcinoma in situ of respiratory system, other/unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).