This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

CD2_INSITU_MELANOMA_EXALLC

Melanoma in situ of lip

Endpoint Browser

CD2_INSITU_MELANOMA_LIP

No definition available.

Suggest a new description

Endpoint definition

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Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D03.0& Cause of death: ICD-10 — D03.0& 2 out of 7 registries used, show all original rules.	16
4. Check minimum number of events None	16
5. Include endpoints None	16
6. Filter based on genotype QC (FinnGen only)	16

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D03
Name in latin: Melanoma in situ labii (oris)

NAME	CD2_INSITU_MELANOMA_LIP
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D030
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D030
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Melanoma in situ of lip based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Melanoma in situ of lip

Case counts by codes

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FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	16	10	6
Unadjusted period prevalence (%)	0.00	0.00	0.00
Median age at first event (years)	62.56	61.74	63.92

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

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CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

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(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(3007853) Bacteria identified in Skin by Aerobe culture

7.37

2.99

1.4

1.8

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

8.43

2.57

3.4

1.9

g/l

109.2

132.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

3.55

1.40

2.8

2.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

2.83

1.12

7.2

2.9

—

(40768804) Tissue Pathology biopsy report

2.44

0.98

3.6

2.0

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

0.00

0.88

0.0

1.9

—

3.5

—

(40768797) Stomach Pathology biopsy report

0.00

0.88

0.0

1.2

—

(42870588) Differential panel, method unspecified - Blood

2.32

0.86

11.9

7.6

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

2.07

0.76

3.9

3.4

—

(3013512) EKG study

1.98

0.60

5.3

5.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.96

0.50

4.0

8.8

—

(3019060) Gas panel - Arterial blood

0.00

0.43

0.0

2.8

—

(3048689) Calprotectin [Mass/mass] in Stool

0.00

0.43

0.0

1.2

—

47.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.51

0.27

6.0

3.0

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.22

0.0

2.1

—

(4010399)

0.00

0.22

0.0

1.1

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

0.00

0.22

0.0

2.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

1.14

0.10

6.3

3.3

—

(3015736) pH of Urine

1.23

0.10

3.6

2.6

—

(3044889) 12 lead EKG panel

0.86

0.10

4.2

4.8

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

5.9

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.0

1.4

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.0

1.4

—

(3025941) Bacteria identified in Stool by Culture

0.00

0.0

1.3

—

(3022621) pH of Urine by Test strip

0.00

0.0

2.1

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

8.3

—

0.0

—

(36660697) Celiac disease serology panel - Serum

0.00

0.0

1.0

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.0

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

0.3

—

(3021589) Normoblasts [#/volume] in Blood

1.11

0.00

28.7

9.3

e9/l

0.0

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

8.3

—

0.0

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

8.3

—

0.0

—

(3018405) Lactate [Moles/volume] in Arterial blood

0.00

0.0

2.4

—

1.2

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.0

2.6

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

0.00

0.0

1.2

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.00

0.0

1.5

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.6

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

11.9

—

(3026008) Bacteria identified in Urine by Culture

0.97

0.00

3.2

—

(3045414) Leukocytes [Presence] in Urine

0.00

0.0

2.5

—

(3000492) Spirometry study

0.00

0.0

2.0

—

(3020891) Body temperature

0.00

0.0

4.0

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.0

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.0

1.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

1.11

0.00

3.0

2.2

—

(3037467) Urinalysis macro (dipstick) panel - Urine

1.05

0.00

5.0

4.8

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

4.2

—

23.0

—

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: CD2_INSITU_MELANOMA_LIP – Melanoma in situ of lip

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Melanoma in situ of lip

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Case counts by code for Melanoma in situ of lip (CD2_INSITU_MELANOMA_LIP)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Relationships between endpoints