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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart CD2_INSITU_ANUS_ANAL_EXALLC for full statistics.

Carcinoma in situ of anus and anal canal

CD2_INSITU_ANUS_ANAL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

  • not C3_ANUS_ANALCANAL
520053

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D01.3&
  • Hospital discharge: ICD-9 230[5-6]
  • Cause of death: ICD-10 D01.3&
  • Cause of death: ICD-9 230[5-6]
  • Cancer registry: Topography ICD-O-3 C21
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

33

4. Check minimum number of events

None

33

5. Include endpoints

None

33

6. Filter based on genotype QC (FinnGen only)

33

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D01
Name in latin
Carcinoma in situ laryngis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 33 20 13
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 63.32 61.93 65.45

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3002256) Pathology report gross observation
18
24
15.30
14.24
1.7
1.1
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
16
39
7.02
7.05
2.6
2.9
e6/l
4.5
1.9
—
10
22
(4035726)
12
22
8.00
6.86
1.3
1.2
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
23
99
5.37
4.98
3.8
3.5
—
—
—
0
0
(40758558) Short blood count panel - Blood
19
73
4.78
4.68
17.1
7.2
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
14
45
4.67
4.25
2.8
2.6
e6/l
0.6
1.1
—
8
27
(36304419) Bacteria [Presence] in Urine
19
79
4.31
4.10
3.9
2.8
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
21
94
4.39
4.09
4.0
3.1
e6/l
23.5
40.9
0.46
16
74
(3018095) Leukocytes [#/volume] in Urine
22
103
4.41
4.01
4.5
3.6
e6/l
132.2
65.9
0.31
16
77
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
6
5
14.20
3.92
1.8
1.0
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
19
81
4.17
3.92
4.2
2.8
e6/l
1.1
0.3
0.63
14
60
(40768804) Tissue Pathology biopsy report
22
105
4.29
3.86
5.1
2.0
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
9
17
6.84
3.83
3.1
1.4
—
—
—
0
0
(3022145) Colonoscopy Study observation
12
39
4.26
3.51
3.4
1.5
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
19
89
3.67
3.28
3.7
2.3
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
10
30
4.35
3.20
1.9
1.7
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
10
33
3.91
2.80
2.6
1.5
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
20
107
3.21
2.63
17.2
10.8
e9/l
0.0
0.0
0.00
14
86
(3023368) Bacteria identified in Blood by Culture
16
75
3.20
2.63
7.9
4.9
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
17
85
3.06
2.48
12.7
4.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
14
65
3.00
2.29
3.4
2.2
—
—
—
0
0
(3014576) Chloride [Moles/volume] in Serum or Plasma
9
33
3.36
2.13
8.0
9.5
mmol/l
103.4
104.7
—
9
33
(3011397) Hemoglobin [Presence] in Urine by Test strip
13
60
2.92
2.12
2.5
4.8
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
8
27
3.57
2.10
2.9
3.8
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
21
128
2.76
2.01
4.8
4.0
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
26
184
2.94
1.82
6.4
4.3
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
7
25
3.27
1.76
8.6
4.5
u/l
262.3
247.5
—
7
25
(3013707) Erythrocyte sedimentation rate by Westergren method
28
214
3.03
1.70
6.4
3.8
mm/h
15.5
11.2
0.68
28
203
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
19
117
2.47
1.69
1.9
2.0
pmol/l
98.4
96.4
—
10
51
(3000494) Fungus identified in Specimen by Culture
8
33
2.87
1.67
1.8
1.3
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
15
87
2.33
1.47
4.0
3.2
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
10
50
2.43
1.33
3.7
2.1
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
21
149
2.13
1.19
2.3
3.0
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
17
116
1.96
1.02
4.3
2.5
ug/l
124.1
93.1
0.59
17
108
(3044889) 12 lead EKG panel
24
188
2.01
1.02
4.5
3.7
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
11
66
2.00
0.93
1.4
1.2
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
8
47
1.92
0.88
3.1
1.8
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
0
24
0.00
0.83
0.0
2.5
—
4.0
—
0
17
(3000991) Gas panel - Venous blood
5
24
2.27
0.78
9.6
9.5
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
14
97
1.77
0.75
5.8
3.2
mmol/l
2.3
2.4
0.23
14
84
(3026493) Urate [Moles/volume] in Serum or Plasma
11
72
1.79
0.70
5.5
2.3
umol/l
390.3
341.4
0.65
11
60
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
20
0.00
0.62
0.0
1.8
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
15
187
0.64
0.53
3.4
2.7
u/l
81.8
42.6
0.74
15
177
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
18
213
0.66
0.47
7.0
4.0
pmol/l
14.3
15.0
0.82
18
191
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
5
31
1.72
0.45
3.0
2.0
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
5
31
1.72
0.45
3.0
1.8
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
24
265
0.65
0.44
5.1
4.6
mmol/l
4.6
4.5
0.10
24
243
(40768797) Stomach Pathology biopsy report
5
33
1.60
0.43
1.0
1.2
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
6
42
1.52
0.38
1.3
1.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
6
45
1.41
0.36
1.7
1.3
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
9
71
1.37
0.29
5.6
2.8
mg/l
65.9
104.7
—
9
40
(3015736) pH of Urine
12
99
1.33
0.24
3.5
4.4
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
0
11
0.00
0.22
0.0
1.7
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
11
0.00
0.22
0.0
1.3
—
—
—
0
0
(3043409) Potassium [Moles/volume] in Arterial blood
0
11
0.00
0.22
0.0
4.8
—
3.8
—
0
11
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
10
0.00
0.22
0.0
2.0
—
79.9
—
0
10
(3020891) Body temperature
0
10
0.00
0.22
0.0
5.8
—
—
—
0
0
(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum
0
10
0.00
0.22
0.0
1.5
—
1.5
—
0
5
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
0
12
0.00
0.21
0.0
4.7
—
1.4
—
0
12
(40760892) CBC W Ordered Manual Differential panel - Blood
7
60
1.21
0.19
3.0
6.7
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
6
75
0.76
0.18
3.7
3.3
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
27
252
1.39
0.18
7.1
6.0
mmol/mol
43.7
39.8
0.90
27
233
(3013512) EKG study
7
84
0.79
0.17
5.7
4.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
8
88
0.88
0.08
2.6
2.8
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
12
109
1.16
0.07
3.3
4.6
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
10
93
1.11
0.02
4.6
3.3
ng/l
2557.6
2003.3
—
10
79
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.4
—
1.1
—
0
9
(3044290) Cell count panel - Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
8
0.00
0.00
0.0
5.4
—
187.4
—
0
8
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.4
—
0.2
—
0
9
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(4094501)
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
3.6
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003181) Sodium [Moles/volume] in Urine
0
5
0.00
0.00
0.0
1.2
—
59.4
—
0
5
(3002523) Influenza virus A Ag [Presence] in Specimen
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
0
7
0.00
0.00
0.0
1.0
—
0.0
—
0
7
(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
2.0
—
30.3
—
0
5
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
7
70
1.00
0.00
1.3
1.6
nmol/l
21.0
20.1
—
7
59
(40768800) Prostate Pathology biopsy report
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_ANUS_ANAL – Carcinoma in situ of anus and anal canal

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).