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This is a non-core endpoint: only basic statistics are computed.

Malignant neoplasms of independent (primary) multiple sites

CD2_INDEPENDENT_MULTIPLE_SITES_NAS_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C97
  • Cause of death: ICD-10 C97

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
C97-C97
Name in latin
Neoplasmata maligna locis multis non dependentibus (primariis)

Similar endpoints

List of similar endpoints to Malignant neoplasms of independent (primary) multiple sites based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 20 8 12
Unadjusted period prevalence (%) 0.00 0.00 0.01
Median age at first event (years) 59.50 45.23 69.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3023368) Bacteria identified in Blood by Culture
10
32
5.25
3.16
5.9
3.6
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
10
37
4.41
2.56
2.2
2.2
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
6
16
4.87
2.12
3.8
1.6
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
8
139
0.29
1.93
6.4
4.5
mu/l
2.0
2.0
—
8
134
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
6
18
4.29
1.91
3.3
3.7
%
16.2
32.8
—
6
18
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
6
19
4.04
1.82
2.0
1.5
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
6
20
3.82
1.73
5.2
1.5
—
—
—
0
0
(3004789) Transferrin [Mass/volume] in Serum or Plasma
6
20
3.82
1.73
3.5
3.3
g/l
1.7
2.3
—
6
20
(3022948) Iron [Moles/volume] in Serum or Plasma
6
21
3.62
1.65
3.5
3.1
umol/l
7.7
16.7
—
6
21
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
5
15
4.07
1.63
1.8
1.1
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
5
16
3.80
1.54
2.0
1.4
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
5
18
3.34
1.37
3.0
6.7
mmol/l
1.2
1.1
—
5
18
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
8
43
2.42
1.04
1.6
2.6
—
—
—
0
0
(40758558) Short blood count panel - Blood
6
33
2.16
0.87
21.8
3.6
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
7
38
2.29
0.85
2.6
1.6
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
10
65
2.08
0.73
5.3
5.5
mmol/l
1.2
1.2
—
10
56
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
9
65
1.70
0.49
4.3
2.9
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
5
33
1.68
0.45
1.2
2.2
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
15
0.00
0.43
0.0
1.7
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
6
43
1.56
0.40
3.0
1.4
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
6
44
1.52
0.39
9.0
3.9
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
10
76
1.63
0.38
7.3
4.4
mmol/l
8.0
7.1
—
10
70
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
12
139
0.66
0.35
9.8
5.8
mmol/mol
48.7
40.5
1.09
12
133
(3013512) EKG study
5
36
1.52
0.26
4.0
3.1
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
10
0.00
0.22
0.0
1.0
—
—
—
0
0
(3000492) Spirometry study
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
13
0.00
0.21
0.0
2.1
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
13
141
0.78
0.21
4.2
4.1
mmol/l
6.1
6.0
0.06
13
134
(3009542) Hematocrit [Volume Fraction] of Blood
14
126
1.37
0.20
23.8
13.0
%
30.0
40.3
—
8
98
(3037467) Urinalysis macro (dipstick) panel - Urine
11
94
1.38
0.19
9.5
3.4
—
—
—
0
0
(3044889) 12 lead EKG panel
9
104
0.76
0.19
3.2
3.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
6
54
1.16
0.10
6.8
2.8
—
—
—
0
0
(3003338) MCHC [Mass/volume]
12
129
0.83
0.09
32.1
14.6
g/l
330.9
332.9
0.25
12
129
(3013707) Erythrocyte sedimentation rate by Westergren method
10
106
0.89
0.01
6.2
3.5
mm/h
29.7
12.5
—
10
101
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
9
90
1.00
0.00
4.0
3.6
—
—
—
0
0
(3015736) pH of Urine
6
59
1.02
0.00
7.2
2.6
—
—
—
0
0
(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
1.2
—
0.0
—
0
5
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
0
5
0.00
0.00
0.0
2.8
—
4.5
—
0
5
(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
1.2
—
0.0
—
0
5
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
0
6
0.00
0.00
0.0
7.7
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
6
65
0.89
0.00
14.8
6.7
e9/l
0.0
0.0
—
6
53
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
5
0.00
0.00
0.0
1.4
—
33.6
—
0
5
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
4.9
—
4.5
—
0
7
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
1.2
—
0.0
—
0
5
(3010421) pH of Blood
0
5
0.00
0.00
0.0
2.8
—
7.5
—
0
5
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
0
5
0.00
0.00
0.0
2.8
—
8.3
—
0
5
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3009214) Lutropin [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
7.2
—
0
6
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: CD2_INDEPENDENT_MULTIPLE_SITES_NAS_EXALLC – Malignant neoplasms of independent (primary) multiple sites

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).