This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Malignant neoplasm, without specification of site, excluding all cancers (controls excluding all cancers)
C3_SECONDARY_WITHOUT_SITESPEC_EXALLC
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1827 |
4. Check minimum number of eventsNone |
1827 |
5. Include endpointsNone |
1827 |
6. Filter based on genotype QC (FinnGen only) |
1827 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE_EXALLC
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm, without specification of site, excluding all cancers (controls excluding all cancers)
based on the number of shared cases.
Similar with more cases:
- Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1827 | 750 | 1077 |
| Unadjusted period prevalence (%) | 0.38 | 0.26 | 0.47 |
| Median age at first event (years) | 70.57 | 69.11 | 71.58 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1122
- Matched controls
- 11218
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
323.0
362
*
8000/3-C80.9
ICD-O-3
Neoplasm, malignant of unknown primary site
+∞
314.8
287
*
C80
ICD-10 Finland
Malignant neoplasm, without specification of site
+∞
257.4
237
*
8140/3-C80.9
ICD-O-3
Adenocarcinoma, NOS, of unknown primary site
+∞
205.7
191
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
197.9
184
*
H02AB02
ATC
dexamethasone; systemic
55.6
185.6
220
49
A03FA01
ATC
metoclopramide; systemic, rectal
9.5
175.3
409
636
JN4BD
NOMESCO Finland
Extensive body CT
15.5
146.7
253
206
A04AA02
ATC
granisetron; systemic, transdermal
+∞
146.1
137
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
139.5
131
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
134.1
126
*
Z51.5
ICD-10 Finland
Palliative care
17.6
127.9
208
143
C80.0
ICD-10 Finland
Malignant neoplasm, primary site unknown, so stated
+∞
122.1
115
*
N02AA05
ATC
oxycodone; systemic
6.4
121.0
369
792
8070/3-C80.9
ICD-O-3
Squamous cell carcinoma, NOS, of unknown primary site
+∞
114.6
108
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
113.5
107
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
113.5
107
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
102.7
97
*
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
1011.0
96.4
93
*
C80.99
ICD-10 Finland
Malignant tumor without specified localization or histology
+∞
89.8
85
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
89.8
85
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
200.1
89.7
92
5
8010/3-C80.9
ICD-O-3
Carcinoma, NOS, of unknown primary site
+∞
88.7
84
*
C80.92
ICD-10 Finland
Malignant tumor without specified localization adenocarcinoma
+∞
84.4
80
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
84.4
80
*
A04AA01
ATC
ondansetron; systemic, rectal
22.9
83.9
123
60
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
83.4
79
*
WF002
NOMESCO Finland
Radical radiotherapy
178.9
80.2
83
5
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
21.6
78.5
117
60
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
74.8
71
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
71.6
68
*
9680/3-C80.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of unknown primary site
+∞
71.6
68
*
116
Kela drug reimbursment
Prostate cancer
+∞
67.4
64
*
JN4AD
NOMESCO Finland
Body CT examination
10.0
65.6
137
154
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
64.2
61
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
32.6
62.2
82
27
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
62.0
59
*
C80.90
ICD-10 Finland
Malignant tumor without specified localization without histology
+∞
61.0
58
*
L03AA02
ATC
filgrastim; parenteral
295.6
55.7
56
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.3
55.3
341
1302
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
8.4
53.2
122
160
C80.9
ICD-10 Finland
Malignant neoplasm, primary site unspecified
+∞
51.4
49
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
50.4
48
*
XX3DW
NOMESCO Finland
Time consuming IT work
7.4
50.0
125
187
JN4CD
NOMESCO Finland
Very extensive body CT
15.6
49.9
83
57
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
49.3
47
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
48.3
46
*
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
23.3
47.2
68
31
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
46.1
44
*
L01BC06
ATC
capecitabine; oral
+∞
46.1
44
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
45.1
43
*
8246/3-C80.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of unknown primary site
+∞
44.0
42
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
43.0
41
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
16.8
42.2
68
43
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
41.9
40
*
L02AE02
ATC
leuprorelin; implant, parenteral
114.3
41.0
44
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
39.8
38
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
38.8
37
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
37.7
36
*
WW500
NOMESCO Finland
Blood transfusion
9.2
36.6
78
90
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
368.5
36.2
36
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
357.8
35.1
35
*
C76.2
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Abdomen
+∞
34.5
33
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
34.5
33
*
8720/3-C80.9
ICD-O-3
Malignant melanoma, NOS, of unknown primary site
+∞
34.5
33
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
39.6
33.6
42
11
WZC30
NOMESCO Finland
Teaching
4.0
32.9
142
393
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
11.7
32.6
61
55
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
8.1
31.7
73
96
1990X
ICD-9 Finland
Malignant neoplasm without specification of site, Disseminated
+∞
31.4
30
*
EMB10
NOMESCO Finland
Tonsillectomy
9.0
30.8
66
77
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
310.2
29.9
30
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.1
29.4
83
146
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
+∞
29.3
28
*
PJA10
NOMESCO Finland
Exploration of lymph nodes
67.8
29.0
33
5
A79
ICPC
Malignancy NOS
299.2
28.9
29
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
153.9
28.8
30
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
153.9
28.8
30
*
XW000
NOMESCO Finland
Bone marrow biopsy
6.5
28.5
76
124
H01CB02
ATC
octreotide; parenteral
+∞
28.2
27
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
28.2
27
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
33.7
27.9
36
11
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
11.5
27.8
52
47
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
148.6
27.7
29
*
HA1AA
NOMESCO Finland
X-ray mammography
10.1
27.4
55
57
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
27.2
26
*
C80.98
ICD-10 Finland
Malignant tumor without specified localization other specified histology
+∞
27.2
26
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
27.2
26
*
115
Kela drug reimbursment
Breast cancer
+∞
27.2
26
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
32.8
27.0
35
11
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
99.1
26.8
29
*
R18
ICD-10 Finland
Ascites
10.2
26.7
53
54
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.5
26.5
81
157
B01AB10
ATC
tinzaparin; parenteral
5.3
26.5
84
170
A04AD12
ATC
aprepitant; systemic
+∞
26.1
25
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
26.1
25
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
138.1
25.7
27
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
25.5
173
667
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
25.1
24
*
C43.99
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin other or unspecified histology
+∞
25.1
24
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
25.1
24
*
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
+∞
25.1
24
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
17.5
25.0
39
23
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
16.1
24.2
39
25
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
24.0
23
*
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
+∞
24.0
23
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
24.0
23
*
8480/3-C80.9
ICD-O-3
Mucinous adenocarcinoma of unknown primary site
+∞
24.0
23
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
23.1
350
2025
L02BB03
ATC
bicalutamide; oral
+∞
23.0
22
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
+∞
23.0
22
*
UJC01
NOMESCO Finland
Scopy of lower throat
15.9
22.9
37
24
ZX120
NOMESCO Finland
Intravenous
3.3
22.8
120
389
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.1
22.4
130
449
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
21.9
21
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
21.9
21
*
C80.91
ICD-10 Finland
Malignant tumor without specified localization epidermoid carcinoma
+∞
21.9
21
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
21.9
21
*
C26.9
ICD-10 Finland
Malignant neoplasm: Ill-defined sites within the digestive system
+∞
21.9
21
*
8240/3-C80.9
ICD-O-3
Neuroendocrine tumor, NOS, of unknown primary site
+∞
21.9
21
*
L02BG04
ATC
letrozole; oral
63.8
21.9
25
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
21.7
252
1294
JDB10
NOMESCO Finland
Percutaneous gastrostomy
11.5
21.5
40
36
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.0
21.4
135
495
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
+∞
20.9
20
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
20.9
20
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
20.9
20
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
20.9
20
*
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
78.3
20.7
23
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.5
20.6
74
172
ZX112
NOMESCO Finland
Subcutaneous
23.9
20.0
28
12
8041/3-C80.9
ICD-O-3
Small cell carcinoma, NOS, of unknown primary site
+∞
19.8
19
*
8249/3-C80.9
ICD-O-3
Neuroendocrine tumor, grade 2 of unknown primary site
+∞
19.8
19
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
19.8
19
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
19.8
19
*
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
10.6
19.7
38
37
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
19.4
171
763
J01MA12
ATC
levofloxacin; systemic
2.1
19.0
236
1238
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
15.1
19.0
31
21
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
18.8
18
*
L01AX03
ATC
temozolomide; systemic
+∞
18.8
18
*
PJD51
NOMESCO Finland
Block dissection of cervical lymph nodes
+∞
18.8
18
*
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
+∞
18.8
18
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
5.5
18.8
56
106
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
71.1
18.7
21
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
71.1
18.7
21
*
R4190
NOMESCO Finland
Nutritional therapy
9.1
18.7
39
44
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
21.2
18.7
27
13
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
8.0
18.7
42
54
D77
ICPC
Malignant digestive neopl other/NOS
193.0
18.6
19
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
17.7
17
*
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
17.7
17
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
+∞
17.7
17
*
C77.9
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph node, unspecified
+∞
17.7
17
*
Y77
ICPC
Malignant neoplasm prostate
182.7
17.6
18
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
182.7
17.6
18
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
10.6
17.2
33
32
JN6AD
NOMESCO Finland
CT of torso and neck
50.8
17.0
20
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.1
17.0
97
333
C77.8
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of multiple regions
+∞
16.7
16
*
C76.8
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Overlapping lesion of other and ill-defined sites
+∞
16.7
16
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
16.7
16
*
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
16.7
16
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
16.7
16
*
E34.0
ICD-10 Finland
Carcinoid syndrome
172.4
16.5
17
*
1XC02
NOMESCO Finland
NA
28.0
16.5
22
8
A98
ICPC
Health maint/preventive medicine
0.6
16.5
605
7482
UDQ22
NOMESCO Finland
Microlaryngoscopy
13.0
16.2
28
22
KCD02
NOMESCO Finland
Transurethral resection of bladder
14.7
15.9
26
18
8020/3-C80.9
ICD-O-3
Carcinoma, undifferentiated, NOS, of unknown primary site
+∞
15.7
15
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
15.7
15
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
15.7
15
*
C77.3
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Axillary and upper limb lymph nodes
+∞
15.7
15
*
UJC20
NOMESCO Finland
Extensive endoscopy to identify diagnosed or suspected primary malignant neoplasm of head or neck
+∞
15.7
15
*
H01CB03
ATC
lanreotide; parenteral
+∞
15.7
15
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
15.7
15
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
6.9
15.4
38
57
B01AB05
ATC
enoxaparin; parenteral
1.8
15.3
290
1779
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.5
15.2
45
85
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.7
15.1
105
409
N02AX02
ATC
tramadol; systemic, rectal
1.7
15.0
437
3059
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.8
14.9
64
177
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
16.7
14.8
23
14
J94.8
ICD-10 Finland
Other specified pleural conditions
6.7
14.7
37
57
C83.00
ICD-10 Finland
Lymphocytic lymphoma
+∞
14.6
14
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
14.6
14
*
C48.89
ICD-10 Finland
Overall malignant tumor of the peritoneum and retroperitoneum other or unspecified tumor
+∞
14.6
14
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
14.6
14
*
C79.3
ICD-10 Finland
Secondary malignant neoplasm of brain and cerebral meninges
+∞
14.6
14
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
36.5
14.5
18
5
ZZR00
NOMESCO Finland
Flap of skin
14.6
14.1
23
16
UJF32
NOMESCO Finland
Coloscopy
1.8
13.8
262
1597
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
76.0
13.6
15
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
+∞
13.6
13
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
13.6
13
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
13.6
13
*
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
+∞
13.6
13
*
HAC20
NOMESCO Finland
Total mastectomy
141.6
13.5
14
*
A06AH03
ATC
naloxegol; oral
26.1
13.4
18
7
R50.9
ICD-10 Finland
Fever, unspecified
2.2
13.3
150
747
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
28.7
13.0
17
6
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
70.6
12.6
14
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
11.2
12.5
23
21
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.6
12.5
57
166
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
12.5
12
*
C48.00
ICD-10 Finland
Malignant tumor of the retroperitoneal space without histology
+∞
12.5
12
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
12.5
12
*
9670/3-C80.9
ICD-O-3
Malignant lymphoma, small B lymphocytic, NOS, of unknown primary site
+∞
12.5
12
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
12.5
12
*
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
+∞
12.5
12
*
L01CB01
ATC
etoposide; systemic
+∞
12.5
12
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
12.4
437
3181
JAH01
NOMESCO Finland
Laparoscopy
4.6
12.1
41
91
JFF10
NOMESCO Finland
Loop enterostomy
65.6
11.6
13
*
JAL30
NOMESCO Finland
Omentectomy
19.1
11.6
17
9
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
11.5
11
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
11.5
11
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
11.5
11
*
JN4ED
NOMESCO Finland
Body CT examination with specail preparation
+∞
11.5
11
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
11.5
11
*
JFB30
NOMESCO Finland
Right hemicolectomy
13.8
11.5
19
14
WX402
NOMESCO Finland
General anaesthesia
2.3
11.5
108
494
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
121.2
11.4
12
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
121.2
11.4
12
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.1
11.3
35
71
JAH00
NOMESCO Finland
Laparotomy
3.9
11.3
45
118
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
7.2
11.1
26
37
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
14.0
11.0
18
13
N02AA01
ATC
morphine; systemic, rectal
7.3
10.8
25
35
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
6.4
10.6
27
43
L02AE03
ATC
goserelin; implant
60.6
10.6
12
*
JAL20
NOMESCO Finland
Excision or destruction of lesion of peritoneum
111.0
10.4
11
*
C43.9
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of skin, unspecified
111.0
10.4
11
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
10.4
10
*
D75
ICPC
Malignant neoplasm colon/rectum
+∞
10.4
10
*
9591/3-C80.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of unknown primary site
+∞
10.4
10
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
10.4
10
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
10.4
10
*
C34.39
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other or unspecified histology
+∞
10.4
10
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
10.4
10
*
C18.19
ICD-10 Finland
Malignant tumor in appendix other or unspecified histology
+∞
10.4
10
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
10.4
10
*
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
+∞
10.4
10
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.8
10.2
33
71
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
10.1
10.0
19
19
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
4.2
10.0
37
91
A07AA02
ATC
nystatin; oral
2.5
9.9
76
314
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
5.5
9.8
28
52
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
26.3
9.8
13
5
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
10.7
9.8
18
17
L02BA01
ATC
tamoxifen; oral
55.5
9.7
11
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
55.5
9.7
11
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.6
9.6
69
277
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
100.8
9.4
10
*
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
100.8
9.4
10
*
8130/2-C67.9
ICD-O-3
Papillary urothelial carcinoma, non-invasive of bladder, NOS
100.8
9.4
10
*
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
30.3
9.4
12
*
M49.5*C79.5
ICD-10 Finland
Metastatic fracture of vertebra
+∞
9.4
9
*
9673/3-C80.9
ICD-O-3
Mantle cell lymphoma of unknown primary site
+∞
9.4
9
*
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
+∞
9.4
9
*
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
+∞
9.4
9
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
9.4
9
*
C76.7
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Other ill-defined sites
+∞
9.4
9
*
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
+∞
9.4
9
*
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
+∞
9.4
9
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
9.4
9
*
C76.0
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Head, face and neck
+∞
9.4
9
*
WF099
NOMESCO Finland
Other radiotherapy
+∞
9.4
9
*
C18.21
ICD-10 Finland
Malignant tumor of the ascending colon invasive carcinoma
+∞
9.4
9
*
C76.1
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Thorax
+∞
9.4
9
*
C79.31
ICD-10 Finland
Secondary malignant tumor of the cerebellum
+∞
9.4
9
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.9
9.3
29
60
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.9
9.2
55
197
UJC02
NOMESCO Finland
Rigid oesophagoscopy
7.5
8.9
20
27
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
18.8
8.9
13
7
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
6.9
8.9
21
31
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
14.1
8.7
14
10
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
14.1
8.7
14
10
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
50.4
8.7
10
*
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
6.2
8.6
22
36
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.2
8.6
43
137
HAB40
NOMESCO Finland
Wedge excision of mammary gland
16.4
8.6
13
8
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.0
8.5
32
81
D48.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Retroperitoneum
90.7
8.4
9
*
LAF16
NOMESCO Finland
Excision of uterus, adnexes and lymph nodes for treatment of ovarian cancer
+∞
8.3
8
*
C26.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of digestive system
+∞
8.3
8
*
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
+∞
8.3
8
*
C48.09
ICD-10 Finland
Malignant tumor of the retroperitoneal space other or unspecified tumor
+∞
8.3
8
*
C77.4
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Inguinal and lower limb lymph nodes
+∞
8.3
8
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
8.3
8
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
8.3
8
*
9699/3-C80.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of unknown primary site
+∞
8.3
8
*
C57.9
ICD-10 Finland
Malignant neoplasm: Female genital organ, unspecified
+∞
8.3
8
*
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
8.3
8
*
9590/3-C80.9
ICD-O-3
Malignant lymphoma, NOS, of unknown primary site
+∞
8.3
8
*
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
+∞
8.3
8
*
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
+∞
8.3
8
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
8.3
8
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
8.3
8
*
C79.0
ICD-10 Finland
Secondary malignant neoplasm of kidney and renal pelvis
+∞
8.3
8
*
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
+∞
8.3
8
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.6
8.3
200
2862
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.2
8.2
80
375
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.5
8.2
63
1210
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.1
8.1
42
138
UGC02
NOMESCO Finland
Rigid bronchoscopy
33.6
8.1
10
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
0.6
8.0
128
2010
M04AA01
ATC
allopurinol; systemic
1.7
7.9
188
1212
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
13.1
7.9
13
10
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
7.9
54
211
Z2446
NOMESCO Finland
Social worker
2.4
7.8
63
269
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
45.3
7.7
9
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.7
7.6
49
185
QX4AT
NOMESCO Finland
Ultrsound guided needle biopsy of skin
25.2
7.6
10
*
S77
ICPC
Malignant neoplasm of skin
25.2
7.6
10
*
K85
ICPC
Elevated blood pressure
0.5
7.5
52
1037
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
10.1
7.5
14
14
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
80.6
7.4
8
*
M05BA02
ATC
clodronic acid; systemic
80.6
7.4
8
*
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
80.6
7.4
8
*
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
80.6
7.4
8
*
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
80.6
7.4
8
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
7.7
7.4
16
21
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
13.5
7.4
12
9
1552X
ICD-9 Finland
Malignant neoplasm of liver and intrahepatic bile ducts, Liver, not specified as primary or secondary[NEOPLASMA MALIGNUMHEPATIS, NON DEFINITUM PRIM/SEC]
+∞
7.3
7
*
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
+∞
7.3
7
*
C34.92
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary adenocarcinoma
+∞
7.3
7
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
7.3
7
*
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
+∞
7.3
7
*
9702/3-C80.9
ICD-O-3
Mature T-cell lymphoma, NOS, of unknown primary site
+∞
7.3
7
*
L02BX02
ATC
degarelix; parenteral
+∞
7.3
7
*
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
+∞
7.3
7
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
7.3
7
*
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
+∞
7.3
7
*
C82.00
ICD-10 Finland
Follicular nodular non-Hodgkin's lymphoma, ungraded
+∞
7.3
7
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
7.3
7
*
C50
ICD-10 Finland
Malignant neoplasm of breast
+∞
7.3
7
*
C78.1
ICD-10 Finland
Secondary malignant neoplasm of mediastinum
+∞
7.3
7
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
7.3
7
*
C88.0
ICD-10 Finland
Waldenström macroglobulinaemia
+∞
7.3
7
*
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
+∞
7.3
7
*
GDC00
NOMESCO Finland
Lobectomy of lung
+∞
7.3
7
*
167
Kela drug reimbursment
Dabrafenib, trametinib and vemurafenib
+∞
7.3
7
*
G03HA01
ATC
cyproterone; systemic
+∞
7.3
7
*
T73
ICPC
Neoplasm endocrine other/unspecified
+∞
7.3
7
*
8090/3-C44.4
ICD-O-3
Basal cell carcinoma, NOS, of skin of scalp and neck
+∞
7.3
7
*
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
+∞
7.3
7
*
C79.39
ICD-10 Finland
Secondary malignant tumor of the meninges, ventricle or other part of the brain
+∞
7.3
7
*
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
9.4
7.3
14
15
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
15.9
7.2
11
7
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
30.2
7.2
9
*
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
30.2
7.2
9
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
0.4
7.0
32
739
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
10.1
7.0
13
13
TKE00
NOMESCO Finland
Needle biopsy of prostate
2.9
7.0
41
146
GD1AD
NOMESCO Finland
Thorax CT examination
2.9
7.0
41
147
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.2
6.9
20
39
A06AD11
ATC
lactulose; oral
1.6
6.9
211
1445
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.7
6.9
45
172
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
13.9
6.9
11
8
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.3
6.8
19
36
L13
ICPC
Hip symptom/complaint
0.5
6.8
54
1027
K83.1
ICD-10 Finland
Obstruction of bile duct
5.7
6.8
18
32
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.6
6.7
28
79
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
22.6
6.7
9
*
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
6.5
6.6
16
25
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
6.6
188
1264
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.9
6.6
25
65
D70.89
ICD-10 Finland
Neutropenic splenomegaly
8.7
6.6
13
15
A09AA02
ATC
multienzymes (lipase, protease etc.)
4.2
6.5
23
56
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.5
6.5
57
1057
TGA30
NOMESCO Finland
Thoracocentesis
6.2
6.5
16
26
D48.49
ICD-10 Finland
Tumor of uncertain or unknown nature in the peritoneum, of unknown origin
70.2
6.4
7
*
SPAT1053
SPAT
Memory test
0.6
6.4
93
1500
L08
ICPC
Shoulder symptom/complaint
0.5
6.3
62
1109
UKC02
NOMESCO Finland
Cystoscopy
1.6
6.3
170
1128
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
9.3
6.3
12
13
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.4
6.3
51
221
C10AA05
ATC
atorvastatin; oral
0.7
6.3
248
3257
362
Kela drug reimbursment
Dabrafenib, trametinib and vemurafenib
+∞
6.3
6
*
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
6.3
6
*
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
+∞
6.3
6
*
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
+∞
6.3
6
*
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
+∞
6.3
6
*
1888X
ICD-9 Finland
Malignant neoplasm of bladder, Other specified sites of bladder
+∞
6.3
6
*
C48.19
ICD-10 Finland
Malignant tumor in specified location in peritoneum other or unspecified histlogy
+∞
6.3
6
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
6.3
6
*
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
+∞
6.3
6
*
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
+∞
6.3
6
*
C20
ICD-10 Finland
Malignant neoplasm of rectum
+∞
6.3
6
*
C84.4
ICD-10 Finland
Peripheral T-cell lymphoma, not elsewhere classified
+∞
6.3
6
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
+∞
6.3
6
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
+∞
6.3
6
*
A04AA03
ATC
tropisetron; systemic
+∞
6.3
6
*
YJ1BD
NOMESCO Finland
Extensive CT examination of abdomen for dose design of radiotherapy
+∞
6.3
6
*
C25.4
ICD-10 Finland
Malignant neoplasm: Endocrine pancreas
+∞
6.3
6
*
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
+∞
6.3
6
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
+∞
6.3
6
*
YN1BD
NOMESCO Finland
Extensive CT examination of extremities for dose design of radiotherapy
+∞
6.3
6
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
6.3
6
*
C18.10
ICD-10 Finland
Malignant tumor of the appendix without histology
+∞
6.3
6
*
C26.0
ICD-10 Finland
Malignant neoplasm: Intestinal tract, part unspecified
+∞
6.3
6
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
6.3
6
*
C79.2
ICD-10 Finland
Secondary malignant neoplasm of skin
+∞
6.3
6
*
B72
ICPC
Hodgkin Lymphoma
+∞
6.3
6
*
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
+∞
6.3
6
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
6.3
6
*
H29
ICPC
Ear symptom/complaint other
0.4
6.2
22
562
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
6.2
131
814
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.1
6.1
22
55
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
2.7
6.0
37
138
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_SECONDARY_WITHOUT_SITESPEC_EXALLC – Malignant neoplasm, without specification of site, excluding all cancers (controls excluding all cancers)
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).