Non-Hodgkin lymphoma, all

C3_NONHODGKIN_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C82, C83, C84, C85
  • Cause of death: ICD-9 200
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 967[0-9]|970[0-2]
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 18146 8018 9686
Only index persons 8756 3843 4913
Unadjusted period prevalence (%)
Whole population 0.26 0.23 0.27
Only index persons 0.17 0.14 0.19
Median age at first event (years)
Whole population 72.37 74.22 70.95
Only index persons 74.18 75.99 72.77

-FinnGen-

Key figures

All Female Male
Number of individuals 1196 381 815
Unadjusted period prevalence (%) 0.33 0.15 0.41
Median age at first event (years) 70.94 69.50 71.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1247
Matched controls
12471
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L03AA13
ATC
pegfilgrastim; parenteral
+∞
323.3
296
*
JN4BD
NOMESCO Finland
Extensive body CT
25.9
323.0
472
286
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
323.0
307
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
289.7
323.0
802
77
L03AA02
ATC
filgrastim; parenteral
673.3
323.0
345
7
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
323.0
345
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
4063.7
323.0
320
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
323.0
382
*
XW000
NOMESCO Finland
Bone marrow biopsy
37.0
311.0
405
160
A03FA01
ATC
metoclopramide; systemic, rectal
14.3
283.6
540
632
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
761.1
258.4
246
*
WW500
NOMESCO Finland
Blood transfusion
35.0
239.7
315
119
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
231.6
215
*
H02AB02
ATC
dexamethasone; systemic
76.7
224.2
252
41
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
2302.9
219.3
206
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
813.6
214.4
205
*
A04AA02
ATC
granisetron; systemic, transdermal
1096.3
196.4
187
*
M04AA01
ATC
allopurinol; systemic
7.4
194.4
578
1310
A04AA01
ATC
ondansetron; systemic, rectal
41.0
192.6
243
73
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
15.0
187.4
332
295
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
98.3
155.8
170
20
D70.82
ICD-10 Finland
Drug-induced neutropenia
161.8
150.1
156
11
Z51.5
ICD-10 Finland
Palliative care
19.6
144.7
226
139
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
142.5
134
*
JN4AD
NOMESCO Finland
Body CT examination
17.6
138.8
226
155
PJA10
NOMESCO Finland
Exploration of lymph nodes
146.6
136.4
143
11
C84.0
ICD-10 Finland
Mycosis fungoides
+∞
133.8
126
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
29.6
132.6
181
71
WF049
NOMESCO Finland
Radiotherapy of metastasis
1361.5
128.5
123
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
128.4
121
*
ZX120
NOMESCO Finland
Intravenous
8.8
127.5
299
432
1XC02
NOMESCO Finland
NA
115.3
124.8
134
13
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.3
124.7
384
822
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
176.4
122.8
127
8
C61
ICD-10 Finland
Malignant neoplasm of prostate
1239.7
117.7
113
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
605.9
113.8
111
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
593.9
111.7
109
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
109.0
103
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
109.0
103
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
106.8
101
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
106.8
101
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
29.4
105.6
144
55
WW300
NOMESCO Finland
Transfer of autologic stem cells
1096.2
104.8
101
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
132.5
102.8
109
9
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
100.4
95
*
N02AA05
ATC
oxycodone; systemic
5.3
99.3
355
878
H02AB06
ATC
prednisolone; systemic
3.5
97.0
786
4044
L01AA02
ATC
chlorambucil; oral
+∞
93.9
89
*
R50.9
ICD-10 Finland
Fever, unspecified
5.0
92.9
348
898
9673/3-C42.1
ICD-O-3
Mantle cell lymphoma of bone marrow
+∞
89.7
85
*
C83.00
ICD-10 Finland
Lymphocytic lymphoma
+∞
85.4
81
*
JN6AD
NOMESCO Finland
CT of torso and neck
94.6
80.1
88
10
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
213.4
78.2
80
*
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
170.7
77.0
80
5
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
+∞
75.8
72
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
74.7
71
*
9700/3-C44.9
ICD-O-3
Mycosis fungoides of skin, NOS
+∞
73.7
70
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
50.5
70.6
85
18
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.4
70.3
178
274
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
13.0
68.7
125
106
ZX112
NOMESCO Finland
Subcutaneous
33.3
68.5
90
29
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.0
67.9
204
395
WF002
NOMESCO Finland
Radical radiotherapy
107.4
65.6
71
7
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.4
65.0
401
1544
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
92.6
63.6
70
8
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
171.2
62.6
65
*
130
Kela drug reimbursment
Malignant tumour
+∞
60.9
58
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
322.9
60.9
61
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
9.1
60.8
133
161
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
59.9
57
*
116
Kela drug reimbursment
Prostate cancer
+∞
59.9
57
*
H02AB07
ATC
prednisone; oral
3.7
59.7
310
1033
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
14.3
59.4
103
78
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
605.5
59.2
58
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
58.8
56
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
56.6
255
749
J05AB11
ATC
valaciclovir; oral
4.2
55.9
235
647
9673/3-C77.9
ICD-O-3
Mantle cell lymphoma of lymph node, NOS
+∞
55.6
53
*
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
288.5
54.6
55
*
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
71.1
53.6
61
9
WW409
NOMESCO Finland
Other aferesis
539.8
52.9
52
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
528.9
51.8
51
*
C84.59
ICD-10 Finland
Other and unspecified T-cell lymphomas
+∞
51.4
49
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
50.3
48
*
C83.0
ICD-10 Finland
Small cell B-cell lymphoma
+∞
49.3
47
*
XX3DW
NOMESCO Finland
Time consuming IT work
6.2
48.7
138
244
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
42.0
48.3
60
15
9591/3-C77.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph node, NOS
+∞
48.2
46
*
9680/3-C77.8
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph nodes of multiple regions
+∞
48.2
46
*
J01MA12
ATC
levofloxacin; systemic
3.0
48.1
344
1420
WZC30
NOMESCO Finland
Teaching
4.2
46.7
195
528
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
22.8
46.2
67
31
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
166.2
46.1
48
*
C88.0
ICD-10 Finland
Waldenström macroglobulinaemia
+∞
46.1
44
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
45.3
621
3675
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
31.4
45.3
60
20
9673/3-C77.8
ICD-O-3
Mantle cell lymphoma of lymph nodes of multiple regions
+∞
45.1
43
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
233.1
44.2
45
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
44.0
42
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
44.0
42
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.9
42.9
111
173
WW402
NOMESCO Finland
Leucoferesis
+∞
41.9
40
*
A41.9
ICD-10 Finland
Sepsis, unspecified
5.8
41.4
124
234
TGC00
NOMESCO Finland
Bronchial lavation
8.2
41.3
95
124
B72
ICPC
Hodgkin Lymphoma
+∞
40.8
39
*
A02BC02
ATC
pantoprazole; systemic
2.3
40.7
819
5704
D70.89
ICD-10 Finland
Neutropenic splenomegaly
23.8
40.0
57
25
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
+∞
39.8
38
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
399.4
39.3
39
*
390
Kela drug reimbursment
Ibrutinib
+∞
38.7
37
*
C84.49
ICD-10 Finland
Peripheral T-cell lymphoma, unspecified cell type
+∞
38.7
37
*
L02AE02
ATC
leuprorelin; implant, parenteral
137.6
37.9
40
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
37.7
36
*
C84.5
ICD-10 Finland
Other mature T/NK-cell lymphomas
+∞
37.7
36
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
9.7
37.7
78
85
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
8.2
37.6
86
111
JN4CD
NOMESCO Finland
Very extensive body CT
10.2
37.1
75
78
D64.9
ICD-10 Finland
Anaemia, unspecified
3.2
37.1
222
796
C84.4
ICD-10 Finland
Peripheral T-cell lymphoma, not elsewhere classified
+∞
36.6
35
*
XX9CD
NOMESCO Finland
Very extensive complementary CT
+∞
36.6
35
*
ZX108
NOMESCO Finland
Inhalation
26.8
35.6
49
19
C82.00
ICD-10 Finland
Follicular nodular non-Hodgkin's lymphoma, ungraded
+∞
34.5
33
*
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
+∞
34.5
33
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
33.5
291
1310
9700/3-C44.5
ICD-O-3
Mycosis fungoides of skin of trunk
+∞
33.5
32
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.0
32.7
94
168
C83.33
ICD-10 Finland
Primary medical lymphoma with large B cells
+∞
32.4
31
*
2008X
ICD-9 Finland
Lymphosarcoma and reticulosarcoma, Other named variants
+∞
32.4
31
*
9680/3-C71.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of brain, NOS
+∞
32.4
31
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.2
30.7
122
311
212
Kela drug reimbursment
Gout
6.0
30.5
87
154
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
+∞
30.3
29
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.5
30.0
153
484
ZX070
NOMESCO Finland
Intensity modified radiotherapy
309.5
29.9
30
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
109.4
29.8
32
*
B01AB10
ATC
tinzaparin; parenteral
4.8
29.5
102
226
1512
Kela drug reimbursment
Ibrutinib
+∞
29.3
28
*
C83.01
ICD-10 Finland
Lymphoplasmacytic lymphoma
+∞
29.3
28
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.1
28.7
175
627
9670/3-C77.9
ICD-O-3
Malignant lymphoma, small B lymphocytic, NOS, of lymph node, NOS
+∞
28.2
27
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
28.2
27
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
28.2
27
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.4
28.2
107
261
D69.5
ICD-10 Finland
Secondary thrombocytopenia
65.6
28.0
32
5
A79
ICPC
Malignancy NOS
148.3
27.7
29
*
L01XE27
ATC
[U] ibrutinib; oral
+∞
27.2
26
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
27.2
26
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
27.2
26
*
L02BB03
ATC
bicalutamide; oral
+∞
27.2
26
*
1AA09
NOMESCO Finland
NA
+∞
27.2
26
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.2
27.0
106
267
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
6.8
27.0
69
106
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
26.9
449
2708
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
98.9
26.7
29
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
26.7
303
1547
9671/3-C42.1
ICD-O-3
Lymphoplasmacytic lymphoma of bone marrow
+∞
26.1
25
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
+∞
26.1
25
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
74.3
25.9
29
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
25.8
149
513
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
25.7
282
1410
ZXE00
NOMESCO Finland
One hour or less
2.0
25.5
474
2966
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
25.1
24
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
132.6
24.7
26
*
C84.51
ICD-10 Finland
Other and unspecified T-cell lymphomas
+∞
24.0
23
*
JN4ED
NOMESCO Finland
Body CT examination with specail preparation
+∞
24.0
23
*
TAB00
NOMESCO Finland
Lumbar puncture
5.2
23.9
76
154
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
27.3
23.6
32
12
A07AA02
ATC
nystatin; oral
3.5
23.5
114
345
AA1BD
NOMESCO Finland
Extensive CT of head and brain
7.5
23.2
55
76
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
55.1
23.1
27
5
C83.34
ICD-10 Finland
Anaplastic large cell lymphoma
+∞
23.0
22
*
J05AB01
ATC
aciclovir; systemic
2.3
22.8
251
1250
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
85.0
22.7
25
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
234.0
22.7
23
*
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
234.0
22.7
23
*
TPJ00
NOMESCO Finland
Biopsy of superficial lymph node
122.2
22.6
24
*
WW200
NOMESCO Finland
Immunization
6.7
22.6
58
90
B01AB05
ATC
enoxaparin; parenteral
2.0
22.3
362
2127
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
22.2
164
662
A04AD12
ATC
aprepitant; systemic
+∞
21.9
21
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
21.9
21
*
C84.41
ICD-10 Finland
Peripheral T-cell lymphoma, medium-sized cell type
+∞
21.9
21
*
J01MA14
ATC
moxifloxacin; systemic
2.9
21.6
142
534
EMA10
NOMESCO Finland
Biopsy of tonsil
61.1
20.9
24
*
9591/3-C77.0
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph nodes of head, face and neck
+∞
20.9
20
*
L01EL01
ATC
ibrutinib; oral
+∞
20.9
20
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
20.9
20
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.1
20.7
117
397
Z2446
NOMESCO Finland
Social worker
3.5
20.0
96
288
C84.1
ICD-10 Finland
Sézary disease
+∞
19.8
19
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
19.8
19
*
9702/3-C77.9
ICD-O-3
Mature T-cell lymphoma, NOS, of lymph node, NOS
+∞
19.8
19
*
L01CB01
ATC
etoposide; systemic
+∞
19.8
19
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
19.8
19
*
2000B
ICD-9 Finland
Lymphosarcoma and reticulosarcoma, Reticulosarcoma[LYMPHOMA MALIGNUM DIFFUSUM]
+∞
19.8
19
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.9
19.0
79
210
HA1AA
NOMESCO Finland
X-ray mammography
6.9
18.9
47
70
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
18.8
18
*
9679/3-C38.3
ICD-O-3
Mediastinal large B-cell lymphoma of mediastinum, NOS
+∞
18.8
18
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
18.8
18
*
9680/3-C42.1
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of bone marrow
+∞
18.8
18
*
115
Kela drug reimbursment
Breast cancer
+∞
18.8
18
*
C83.89
ICD-10 Finland
Other types of diffuse non-Hodgkin's lymphoma
+∞
18.8
18
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
18.8
18
*
L01BB05
ATC
fludarabine; systemic
+∞
18.8
18
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
8.4
18.8
41
50
C90.0
ICD-10 Finland
Multiple myeloma
192.7
18.6
19
*
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
4.5
18.6
67
156
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
44.7
18.3
22
5
127
Kela drug reimbursment
Transplant complication
9.5
18.2
37
40
L26
ICD-10 Finland
Exfoliative dermatitis
27.1
17.8
24
9
9680/3-C80.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of unknown primary site
+∞
17.7
17
*
C82.0
ICD-10 Finland
Follicular lymphoma grade I
+∞
17.7
17
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
17.7
17
*
C83.8
ICD-10 Finland
Other non-follicular lymphoma
+∞
17.7
17
*
Y77
ICPC
Malignant neoplasm prostate
96.4
17.6
19
*
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
182.4
17.6
18
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.3
17.3
53
104
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.1
17.2
68
173
E83.50
ICD-10 Finland
Hypercalcemia
10.6
17.2
33
32
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
26.0
16.9
23
9
D07AB08
ATC
desonide; topical
2.5
16.7
142
617
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
16.7
16
*
C85.7
ICD-10 Finland
Other specified types of non-Hodgkin lymphoma
+∞
16.7
16
*
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
16.7
16
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
16.7
16
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
16.7
16
*
L01BC06
ATC
capecitabine; oral
+∞
16.7
16
*
9673/3-C09.9
ICD-O-3
Mantle cell lymphoma of tonsil, NOS
+∞
16.7
16
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
8.2
16.3
36
45
N02AX02
ATC
tramadol; systemic, rectal
1.7
16.1
494
3499
GD1AD
NOMESCO Finland
Thorax CT examination
3.8
16.0
68
185
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
21.3
16.0
23
11
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.1
15.9
207
1097
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
60.8
15.8
18
*
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
+∞
15.7
15
*
9702/3-C77.8
ICD-O-3
Mature T-cell lymphoma, NOS, of lymph nodes of multiple regions
+∞
15.7
15
*
9591/3-C77.2
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of intra-abdominal lymph nodes
+∞
15.7
15
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
15.7
15
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
15.7
15
*
9670/3-C77.0
ICD-O-3
Malignant lymphoma, small B lymphocytic, NOS, of lymph nodes of head, face and neck
+∞
15.7
15
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
15.5
348
2239
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
11.0
15.5
29
27
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
38.6
15.4
19
5
TQW99
NOMESCO Finland
Other minor procedure on skin
3.8
15.2
64
173
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
15.0
425
2929
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
14.9
500
3604
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
14.9
401
2720
J02AC03
ATC
voriconazole; systemic
57.4
14.8
17
*
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
25.4
14.7
20
8
C83.2
ICD-10 Finland
Mixed small and large cell (diffuse) non-Hodgkin's lymphoma
+∞
14.6
14
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
14.6
14
*
Z52.89
ICD-10 Finland
Donor of other organ or tissue
+∞
14.6
14
*
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
+∞
14.6
14
*
Z2221
NOMESCO Finland
Medical doctor
1.8
14.5
302
1891
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
14.4
271
1642
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.0
14.3
58
152
N05CF01
ATC
zopiclone; oral
1.7
14.2
417
2891
HAB40
NOMESCO Finland
Wedge excision of mammary gland
43.0
14.1
17
*
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
11.0
14.0
26
24
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
11.0
14.0
26
24
H02AB09
ATC
hydrocortisone; systemic
5.3
13.9
42
82
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
53.9
13.8
16
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
24.1
13.8
19
8
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
7.4
13.8
32
44
KCD02
NOMESCO Finland
Transurethral resection of bladder
10.6
13.8
26
25
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
13.8
13.7
23
17
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
8.1
13.6
30
38
9700/3-C44.7
ICD-O-3
Mycosis fungoides of skin of lower limb and hip
+∞
13.6
13
*
C83.32
ICD-10 Finland
Centroblastic diffuse non-Hodgkin's lymphoma
+∞
13.6
13
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
13.6
13
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
13.6
13
*
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
13.6
13
*
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
+∞
13.6
13
*
C83.35
ICD-10 Finland
T-cell-rich B-cell lymphoma
+∞
13.6
13
*
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
34.4
13.5
17
5
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
13.5
173
907
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
16.4
13.5
21
13
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
141.4
13.5
14
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
141.4
13.5
14
*
R4110
NOMESCO Finland
Physiotherapy
1.8
13.4
281
1758
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
7.1
13.4
32
46
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
13.4
133
623
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
40.5
13.2
16
*
A98
ICPC
Health maint/preventive medicine
0.6
13.1
778
9060
ZZR00
NOMESCO Finland
Flap of skin
10.2
13.0
25
25
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
12.9
98
399
Z3231
NOMESCO Finland
Registered nurse
1.7
12.9
306
1986
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
12.4
12.6
22
18
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
32.4
12.6
16
5
B02.9
ICD-10 Finland
Zoster without complication
2.7
12.5
86
332
C81.3
ICD-10 Finland
Lymphocyte depleted classical Hodgkin lymphoma
+∞
12.5
12
*
FM1FN
NOMESCO Finland
Heart function isotope examination
+∞
12.5
12
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
12.5
12
*
C83.5
ICD-10 Finland
Lymphoblastic (diffuse) lymphoma
+∞
12.5
12
*
2009X
ICD-9 Finland
Lymphosarcoma and reticulosarcoma[LYMPHOMA MALIGNUM (NON-HODGKIN) NUD]
+∞
12.5
12
*
9670/3-C80.9
ICD-O-3
Malignant lymphoma, small B lymphocytic, NOS, of unknown primary site
+∞
12.5
12
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
12.5
12
*
C80.99
ICD-10 Finland
Malignant tumor without specified localization or histology
+∞
12.5
12
*
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
+∞
12.5
12
*
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
+∞
12.5
12
*
C83.59
ICD-10 Finland
Lymphoblastic lymphoma of indeterminate type
+∞
12.5
12
*
B00.2
ICD-10 Finland
Herpesviral gingivostomatitis and pharyngotonsillitis
20.3
12.5
18
9
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
131.2
12.5
13
*
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
131.2
12.5
13
*
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
131.2
12.5
13
*
1CX01
NOMESCO Finland
NA
131.2
12.5
13
*
N03AX16
ATC
pregabalin; oral
1.8
12.4
249
1534
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.2
12.4
66
217
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.8
12.3
34
60
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
37.9
12.2
15
*
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
37.9
12.2
15
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.7
12.2
83
318
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
12.0
349
2393
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
47.1
11.9
14
*
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
6.5
11.9
30
47
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
7.1
11.8
28
40
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
65.6
11.6
13
*
134
Kela drug reimbursment
General erythroderma
11.2
11.6
21
19
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.2
11.5
61
200
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
11.5
11
*
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
+∞
11.5
11
*
9670/3-C42.1
ICD-O-3
Malignant lymphoma, small B lymphocytic, NOS, of bone marrow
+∞
11.5
11
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
11.5
11
*
C84.43
ICD-10 Finland
Peripheral T-cell lymphoma, large cell type
+∞
11.5
11
*
1XX25
NOMESCO Finland
NA
+∞
11.5
11
*
YN1BD
NOMESCO Finland
Extensive CT examination of extremities for dose design of radiotherapy
+∞
11.5
11
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
11.5
11
*
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
+∞
11.5
11
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.5
11.4
39
88
UJF32
NOMESCO Finland
Coloscopy
1.7
11.4
279
1818
A06AH03
ATC
naloxegol; oral
17.2
11.2
17
10
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
5.6
11.1
31
56
D05BB02
ATC
acitretin; oral
4.0
11.0
43
110
L57.0
ICD-10 Finland
Actinic keratosis
2.2
11.0
108
505
ZXD05
NOMESCO Finland
Urgent procedure
1.6
10.9
363
2565
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.4
10.9
51
153
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
6.2
10.8
28
46
R06AE07
ATC
cetirizine; oral
1.6
10.8
390
2811
ZXC50
NOMESCO Finland
Cryotherapy
4.2
10.7
39
94
ED1AA
NOMESCO Finland
Mandipular X-ray examination
13.0
10.7
18
14
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
5.6
10.6
30
55
TK800
NOMESCO Finland
Hemodialysis
3.8
10.5
43
115
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.7
10.4
29
52
WX110
NOMESCO Finland
Local anesthesy
1.5
10.4
629
5068
V03AF03
ATC
calcium folinate; systemic
110.9
10.4
11
*
Z51.3
ICD-10 Finland
Blood transfusion (without reported diagnosis)
110.9
10.4
11
*
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
110.9
10.4
11
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
110.9
10.4
11
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
110.9
10.4
11
*
Z85.7
ICD-10 Finland
Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
+∞
10.4
10
*
9680/3-C16.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of stomach, NOS
+∞
10.4
10
*
9591/3-C77.8
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph nodes of multiple regions
+∞
10.4
10
*
C82.7
ICD-10 Finland
Other types of follicular lymphoma
+∞
10.4
10
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
10.4
10
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
10.4
10
*
C81.0
ICD-10 Finland
Nodular lymphocyte predominant Hodgkin lymphoma
+∞
10.4
10
*
YJ1BD
NOMESCO Finland
Extensive CT examination of abdomen for dose design of radiotherapy
+∞
10.4
10
*
XX1AD
NOMESCO Finland
Other CT-examination
+∞
10.4
10
*
3AA13
NOMESCO Finland
NA
+∞
10.4
10
*
9670/3-C77.8
ICD-O-3
Malignant lymphoma, small B lymphocytic, NOS, of lymph nodes of multiple regions
+∞
10.4
10
*
JAL00
NOMESCO Finland
Biopsy of peritoneum
32.8
10.3
13
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.2
10.3
54
176
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.0
10.3
59
204
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
3.8
10.2
42
113
JFB00
NOMESCO Finland
Partial resection of small intestine
4.9
10.2
32
66
A02BC01
ATC
omeprazole; systemic
1.6
10.2
338
2377
E0000UV
ATC
NA
1.5
10.2
391
2850
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
10.1
276
1847
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
14.7
10.0
16
11
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.6
10.0
28
51
L01AA01
ATC
cyclophosphamide; systemic
12.3
9.9
17
14
B74
ICPC
Malignant neoplasm blood other
26.2
9.8
13
5
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
26.2
9.8
13
5
J02AC01
ATC
fluconazole; systemic
1.6
9.7
305
2113
C03CA01
ATC
furosemide; systemic
1.5
9.7
485
3741
AAA10
NOMESCO Finland
Biopsy through craniotomy
55.4
9.7
11
*
A41.8
ICD-10 Finland
Other specified sepsis
3.9
9.6
38
100
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
10.1
9.5
18
18
JMA10
NOMESCO Finland
Transabdominal total splenectomy
15.2
9.5
15
10
A05AA02
ATC
ursodeoxycholic acid; oral
7.2
9.5
22
31
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.9
9.5
55
192
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.3
9.5
21
662
TQW80
NOMESCO Finland
Local dermatologic skincare
3.8
9.5
39
106
ZX131
NOMESCO Finland
Intrathecal
100.7
9.4
10
*
C18.00
ICD-10 Finland
Malignant tumor of the caecum without histology
100.7
9.4
10
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
100.7
9.4
10
*
ZX196
NOMESCO Finland
NA
100.7
9.4
10
*
DAB10
NOMESCO Finland
Partial excision of auricle
100.7
9.4
10
*
L04AD01
ATC
ciclosporin; systemic
4.6
9.4
31
68
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
5.2
9.4
28
55
TPX15
NOMESCO Finland
Removal of vascular injection port
30.2
9.4
12
*
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
17.7
9.4
14
8
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.2
9.4
34
82
8090/3-C44.2
ICD-O-3
Basal cell carcinoma, NOS, of external ear
+∞
9.4
9
*
YN1AD
NOMESCO Finland
CT examination of extremities for dose design of radiotherapy
+∞
9.4
9
*
C88.9
ICD-10 Finland
Malignant immunoproliferative disease, unspecified
+∞
9.4
9
*
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
+∞
9.4
9
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
9.4
9
*
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
9.4
9
*
9691/3-C77.9
ICD-O-3
Follicular lymphoma, grade 2 of lymph node, NOS
+∞
9.4
9
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
+∞
9.4
9
*
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
+∞
9.4
9
*
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
+∞
9.4
9
*
8090/3-C44.4
ICD-O-3
Basal cell carcinoma, NOS, of skin of scalp and neck
+∞
9.4
9
*
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
9.4
9
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
9.4
9
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
9.4
9
*
9673/3-C80.9
ICD-O-3
Mantle cell lymphoma of unknown primary site
+∞
9.4
9
*
9670/3-C77.3
ICD-O-3
Malignant lymphoma, small B lymphocytic, NOS, of lymph nodes of axilla or arm
+∞
9.4
9
*
9700/3-C44.6
ICD-O-3
Mycosis fungoides of skin of upper limb and shoulder
+∞
9.4
9
*
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
7.0
9.3
22
32
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
13.8
9.2
15
11
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
4.4
9.1
31
71
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
8.7
116
616
120
Kela drug reimbursment
Hypogammaglobulinaemia
50.3
8.7
10
*
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
50.3
8.7
10
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
8.3
8.6
18
22
6BA02
NOMESCO Finland
NA
16.4
8.6
13
8
L41.8
ICD-10 Finland
Other parapsoriasis
27.7
8.5
11
*
D10.4
ICD-10 Finland
Benign neoplasm: Tonsil
27.7
8.5
11
*
4701
FHL
Neck lymph node removal
27.7
8.5
11
*
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
27.7
8.5
11
*
WF099
NOMESCO Finland
Other radiotherapy
27.7
8.5
11
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
27.7
8.5
11
*
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.7
8.5
35
96
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.4
8.4
70
301
HAC20
NOMESCO Finland
Total mastectomy
90.6
8.4
9
*
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
90.6
8.4
9
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
5.1
8.4
25
50
9591/3-C77.3
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph nodes of axilla or arm
+∞
8.3
8
*
9702/3-C42.1
ICD-O-3
Mature T-cell lymphoma, NOS, of bone marrow
+∞
8.3
8
*
Z08.9
ICD-10 Finland
Follow-up examination after unspecified treatment for malignant neoplasm
+∞
8.3
8
*
C76.2
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Abdomen
+∞
8.3
8
*
9823/3-C77.9
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of lymph node, NOS
+∞
8.3
8
*
C83.7
ICD-10 Finland
Burkitt lymphoma
+∞
8.3
8
*
C80.90
ICD-10 Finland
Malignant tumor without specified localization without histology
+∞
8.3
8
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
8.3
8
*
B73
ICPC
Leukaemia
+∞
8.3
8
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
8.3
8
*
C83.71
ICD-10 Finland
Burkitt's tumour
+∞
8.3
8
*
3AX16
NOMESCO Finland
NA
+∞
8.3
8
*
C83.51
ICD-10 Finland
B-lymphoblastic lymphoma or leukemia
+∞
8.3
8
*
D76.1
ICD-10 Finland
Haemophagocytic lymphohistiocytosis
+∞
8.3
8
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
8.3
8
*
N02AA01
ATC
morphine; systemic, rectal
6.3
8.3
21
34
P20
ICPC
Memory disturbance
0.5
8.3
76
1389
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
4.8
8.3
26
55
J01DB01
ATC
cefalexin; oral
1.4
8.3
844
7390
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
8.2
77
352
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.5
8.2
63
261
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
4.0
8.2
31
79
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
5.7
8.1
22
39
ZQZ00
NOMESCO Finland
Treatment of several skin areas
33.6
8.1
10
*
J35.1
ICD-10 Finland
Hypertrophy of tonsils
9.0
8.0
16
18
EMB10
NOMESCO Finland
Tonsillectomy
3.6
8.0
34
96
L04AA06
ATC
mycophenolic acid; systemic
4.8
8.0
25
53
C10AA07
ATC
rosuvastatin; oral
0.6
7.9
130
2036
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
45.2
7.7
9
*
I88.9
ICD-10 Finland
Nonspecific lymphadenitis, unspecified
18.5
7.6
11
6
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.4
7.6
31
749
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.3
7.5
36
112
N06DX01
ATC
memantine; oral
0.4
7.5
37
830
C44.39
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face other or unspecified histology
80.5
7.4
8
*
S77
ICPC
Malignant neoplasm of skin
80.5
7.4
8
*
C44.10
ICD-10 Finland
Malignant tumor of the skin of the eyelids including the corner of the eye without histology
80.5
7.4
8
*
D48.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Retroperitoneum
80.5
7.4
8
*
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
80.5
7.4
8
*
R4190
NOMESCO Finland
Nutritional therapy
4.1
7.4
27
67
GEA00
NOMESCO Finland
Mediastinoscopy
13.4
7.4
12
9
WX002
NOMESCO Finland
Sedation and analgesia
1.6
7.4
198
1314
C50.99
ICD-10 Finland
Breast, unspecified
+∞
7.3
7
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
7.3
7
*
9591/3-C42.1
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of bone marrow
+∞
7.3
7
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
7.3
7
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
7.3
7
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
7.3
7
*
9591/3-C80.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of unknown primary site
+∞
7.3
7
*
L41.4
ICD-10 Finland
Large plaque parapsoriasis
+∞
7.3
7
*
8090/3-C44.1
ICD-O-3
Basal cell carcinoma, NOS, of eyelid
+∞
7.3
7
*
9702/3-C80.9
ICD-O-3
Mature T-cell lymphoma, NOS, of unknown primary site
+∞
7.3
7
*
3AF07
NOMESCO Finland
NA
+∞
7.3
7
*
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
+∞
7.3
7
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
7.3
7
*
9591/3-C16.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of stomach, NOS
+∞
7.3
7
*
9680/3-C62.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of testis, NOS
+∞
7.3
7
*
9690/3-C77.9
ICD-O-3
Follicular lymphoma, NOS, of lymph node, NOS
+∞
7.3
7
*
C44.22
ICD-10 Finland
Spinocellular carcinoma of the skin of the outer ear and the outer ear canal
+∞
7.3
7
*
9680/3-C09.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of tonsil, NOS
+∞
7.3
7
*
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
9.4
7.3
14
15
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.6
7.2
50
196
L02AE03
ATC
goserelin; implant
30.2
7.2
9
*
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
30.2
7.2
9
*
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
20.1
7.1
10
5
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
3.9
7.1
27
70
ZXF99
NOMESCO Finland
Other r3eason to interrupt procedure
12.1
7.1
12
10
WW200
SPAT
NA
0.3
7.1
20
560
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
10.1
7.0
13
13
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
10.1
7.0
13
13
L02BG04
ATC
letrozole; oral
10.1
7.0
13
13
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.0
7.0
26
66
Z51.88
ICD-10 Finland
Other specified medical care
3.7
7.0
28
76
A49.8
ICD-10 Finland
Other bacterial infections of unspecified site
5.9
6.9
18
31
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
11.0
6.8
12
11
A06AD11
ATC
lactulose; oral
1.6
6.8
209
1433
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
40.3
6.8
8
*
L41.9
ICD-10 Finland
Parapsoriasis, unspecified
40.3
6.8
8
*
GD2AT
NOMESCO Finland
Cytology of the lungs with ultrasound guidance
40.3
6.8
8
*
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.0
6.8
36
122
D07AA02
ATC
hydrocortisone; topical
1.7
6.7
130
784
C10AA01
ATC
simvastatin; oral
0.7
6.7
423
5171
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
7.2
6.7
15
21
I89.9
ICD-10 Finland
Noninfective disorder of lymphatic vessels and lymph nodes, unspecified
22.6
6.7
9
*
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
6.5
6.6
16
25
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
4.6
6.6
21
46
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.5
6.6
47
190
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
8.7
6.6
13
15
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
3.3
6.5
31
97
A10BK03
ATC
empagliflozin; oral
0.3
6.5
12
414
D07AC01
ATC
betamethasone; topical
1.4
6.5
357
2756
RS221
NOMESCO Finland
NA
4.5
6.5
21
47
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
0.7
6.5
215
2925
N06DA02
ATC
donepezil; oral
0.4
6.5
30
691
JAH01
NOMESCO Finland
Laparoscopy
3.2
6.4
31
98
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
70.2
6.4
7
*
1XX32
NOMESCO Finland
NA
70.2
6.4
7
*
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
70.2
6.4
7
*
KFC10
NOMESCO Finland
Bilateral orchiectomy
70.2
6.4
7
*
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
0.6
6.4
150
2185
7856A
ICD-9 Finland
Symptoms involving cardiovascular system, Enlargement of lymph nodes
14.4
6.4
10
7
G04BE03
ATC
sildenafil; oral
14.4
6.4
10
7
J94.8
ICD-10 Finland
Other specified pleural conditions
3.7
6.4
26
72
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.9
6.4
19
39
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.6
6.4
45
180
XQ848
NOMESCO Finland
Dermatological photography
3.5
6.3
27
78
N05AX08
ATC
risperidone; systemic
0.5
6.3
36
767
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
6.0
6.3
16
27
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
11.1
6.3
11
10
L04AA01
ATC
[U] ciclosporin; systemic
4.6
6.3
20
44
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.3
320
2431
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.7
6.3
235
3132
KAC10
NOMESCO Finland
Total nephrectomy with capsule
18.1
6.3
9
5
C83
ICD-10 Finland
Non-follicular lymphoma
+∞
6.3
6
*
D73.9
ICD-10 Finland
Disease of spleen, unspecified
+∞
6.3
6
*
WE300
NOMESCO Finland
Profylactive therapy of malignancy with biomoidiers
+∞
6.3
6
*
9698/3-C77.9
ICD-O-3
Follicular lymphoma, grade 3 of lymph node, NOS
+∞
6.3
6
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
C44.50
ICD-10 Finland
Malignant tumor of the skin on the torso without histology
+∞
6.3
6
*
C84.42
ICD-10 Finland
Peripheral T-cell lymphoma, both medium and large cell type
+∞
6.3
6
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
6.3
6
*
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
+∞
6.3
6
*
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
6.3
6
*
C83.40
ICD-10 Finland
Immunoblast large cell lymphoma
+∞
6.3
6
*
9673/3-C77.0
ICD-O-3
Mantle cell lymphoma of lymph nodes of head, face and neck
+∞
6.3
6
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
6.3
6
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
6.3
6
*
C38.1
ICD-10 Finland
Malignant neoplasm: Anterior mediastinum
+∞
6.3
6
*
3AA02
NOMESCO Finland
NA
+∞
6.3
6
*
C44.62
ICD-10 Finland
Spinocellular carcinoma of the skin of the upper extremity including the shoulder
+∞
6.3
6
*
9673/3-C77.4
ICD-O-3
Mantle cell lymphoma of lymph nodes of inguinal region or leg
+∞
6.3
6
*
JAH21
NOMESCO Finland
Staging laparoscopy
+∞
6.3
6
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
6.3
6
*
2AX05
NOMESCO Finland
NA
+∞
6.3
6
*
17402
ICD-8 Finland
Malignant neoplasm of breast, Glandulae
+∞
6.3
6
*
9695/3-C77.8
ICD-O-3
Follicular lymphoma, grade 1 of lymph nodes of multiple regions
+∞
6.3
6
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
6.3
6
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
6.3
6
*
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
+∞
6.3
6
*
C81.2
ICD-10 Finland
Mixed cellularity classical Hodgkin lymphoma
+∞
6.3
6
*
9701/3-C44.9
ICD-O-3
Sezary syndrome of skin, NOS
+∞
6.3
6
*
372
Kela drug reimbursment
Idelalisib
+∞
6.3
6
*
9670/3-C77.4
ICD-O-3
Malignant lymphoma, small B lymphocytic, NOS, of lymph nodes of inguinal region or leg
+∞
6.3
6
*
L01XX47
ATC
[U] idelalisib; oral
+∞
6.3
6
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
6.2
75
386
L03AB05
ATC
interferon alfa-2b; parenteral
26.8
6.2
8
*
GEA20
NOMESCO Finland
Mediastinoscopy with excision of lesion
26.8
6.2
8
*
EMA30
NOMESCO Finland
Biopsy of rhinopharynx
26.8
6.2
8
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
26.8
6.2
8
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
4.1
6.2
22
54
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.1
6.2
31
101
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.9
6.1
35
122
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
12.6
6.1
10
8
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.4
6.1
27
81
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
4.4
6.1
20
46
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
6.0
138
876

Mortality – FinRegistry

Association

Association between endpoint C3_NONHODGKIN_EXALLC and mortality.

Females

Parameter HR [95% CI] p-value
C3_NONHODGKIN_EXALLC 3.9 [3.18, 4.79] < 0.001
Birth year 0.994 [0.99, 1.0] 0.165

During the follow-up period (1.1.1998 — 31.12.2019), 588 out of 1250 females with C3_NONHODGKIN_EXALLC died.

Males

Parameter HR [95% CI] p-value
C3_NONHODGKIN_EXALLC 2.908 [2.43, 3.48] < 0.001
Birth year 0.989 [0.98, 1.0] 0.025

During the follow-up period (1.1.1998 — 31.12.2019), 1028 out of 2037 males with C3_NONHODGKIN_EXALLC died.

Mortality risk

Mortality risk for people of age

years, who have C3_NONHODGKIN_EXALLC.

N-year risk Females Males
1 0.316% 0.695%
5 1.899% 3.977%
10 5.015% 8.713%
15 9.9% 16.252%
20 16.585% 27.513%

Relationships between endpoints

Index endpoint: C3_NONHODGKIN_EXALLC – Non-Hodgkin lymphoma, all

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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