info icon

This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Colorectal squamous cell carcinoma, excluding all cancers (controls excluding all cancers)

C3_COLORECTAL_SQUAM_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C1[8-9]|C20
  • Cancer registry: Morphology ICD-O-3 8070
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

38

4. Check minimum number of events

None

38

5. Include endpoints

None

38

6. Filter based on genotype QC (FinnGen only)

38

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Colorectal squamous cell carcinoma, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 38 31 7
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 62.06 59.94 71.42

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
28
14
73.20
40.23
3.4
1.6
ug/l
2.1
3.6
—
23
9
(3022145) Colonoscopy Study observation
25
31
21.65
21.50
2.8
1.2
—
—
—
0
0
(4035726)
18
9
36.18
14.21
1.4
1.0
—
—
—
0
0
(3012095) Magnesium [Moles/volume] in Serum or Plasma
17
42
6.51
7.28
2.3
1.8
mmol/l
0.8
0.8
1.11
17
37
(3023368) Bacteria identified in Blood by Culture
20
60
5.93
6.91
6.3
3.7
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
28
116
6.37
6.60
3.5
1.5
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
29
129
6.24
6.22
9.0
3.9
g/l
35.3
36.1
0.37
29
121
(40758558) Short blood count panel - Blood
18
65
4.36
4.66
10.1
4.4
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
22
93
4.24
4.59
8.4
2.0
mmol/l
2.3
2.4
0.55
22
77
(3033658) Prothrombin time (PT) actual/Normal
17
63
4.07
4.18
3.2
3.3
%
101.1
93.6
0.52
17
63
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
9
16
7.00
3.93
1.2
1.4
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
21
96
3.65
3.73
3.6
2.9
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
16
62
3.73
3.62
2.6
1.9
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
29
169
4.01
3.60
11.4
3.3
umol/l
8.0
9.8
2.12
29
155
(3002256) Pathology report gross observation
11
33
4.28
3.50
2.0
1.1
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
7
11
7.50
3.35
6.1
6.9
mmol/l
24.7
26.0
—
7
11
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
13
47
3.68
3.20
2.5
2.8
e6/l
2.7
5.3
—
7
26
(36304419) Bacteria [Presence] in Urine
17
78
3.13
2.85
3.7
2.8
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
20
101
3.07
2.85
5.7
6.7
inr
1.0
1.2
—
5
29
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
23
127
3.05
2.78
5.8
3.7
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
17
81
2.99
2.64
3.1
1.9
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
12
53
2.85
2.06
5.0
2.0
mmol/l
2.5
2.4
0.33
12
40
(3037467) Urinalysis macro (dipstick) panel - Urine
30
215
2.87
2.05
5.6
4.0
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
6
16
4.24
2.02
1.0
1.3
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
9
35
3.05
1.96
2.8
1.7
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
7
23
3.49
1.90
1.7
1.9
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
7
23
3.49
1.90
1.7
1.9
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
5
12
4.62
1.88
2.4
1.7
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
18
102
2.45
1.88
5.0
5.1
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
12
56
2.67
1.85
2.1
2.5
e6/l
0.2
1.2
—
6
34
(3014007) Fractional oxyhemoglobin in Arterial blood
5
13
4.25
1.77
6.0
8.7
%
97.4
93.4
—
5
13
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
5
13
4.25
1.77
9.4
7.8
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
23
150
2.35
1.71
3.8
5.1
e9/l
1.3
1.8
2.50
18
137
(3006315) Basophils [#/volume] in Blood
23
150
2.35
1.71
3.5
5.1
e9/l
0.0
0.0
1.49
17
134
(3001604) Monocytes [#/volume] in Blood
23
150
2.35
1.71
3.4
5.0
e9/l
0.5
0.5
0.07
17
134
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
5
14
3.94
1.67
6.0
7.9
%
0.9
1.7
—
5
14
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
5
14
3.94
1.67
6.0
7.9
%
0.4
0.8
—
5
14
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
5
15
3.67
1.57
1.0
1.1
—
—
—
0
0
(3000492) Spirometry study
6
21
3.19
1.57
1.0
1.2
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
7
28
2.83
1.54
1.3
1.5
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
23
155
2.23
1.53
4.3
5.1
e9/l
0.2
0.2
0.51
18
139
(3021589) Normoblasts [#/volume] in Blood
19
119
2.19
1.51
17.2
8.1
e9/l
0.0
0.0
0.00
13
96
(3002173) Hemoglobin [Mass/volume] in Arterial blood
6
24
2.77
1.36
8.3
6.8
g/l
112.7
123.8
—
6
24
(3001019) Free T4 and TSH panel - Serum or Plasma
5
18
3.04
1.33
1.8
1.6
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
19
124
2.06
1.31
2.2
1.8
pmol/l
87.1
99.0
—
10
47
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
13
73
2.19
1.31
1.9
1.3
—
—
—
0
0
(3000991) Gas panel - Venous blood
5
19
2.87
1.25
6.4
7.8
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
21
2.58
1.12
1.6
2.3
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
7
33
2.37
1.12
1.1
1.5
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
16
105
1.90
1.04
4.8
2.1
u/l
57.4
56.2
0.06
16
96
(3003694) ABO and Rh group [Type] in Blood
11
66
1.94
0.90
1.3
1.2
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
6
31
2.11
0.89
8.3
6.2
mmol/l
-0.0
2.2
—
6
25
(40760892) CBC W Ordered Manual Differential panel - Blood
10
59
1.94
0.86
4.6
4.2
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
27
0.00
0.81
0.0
1.1
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
27
311
0.54
0.79
3.7
6.2
mmol/mol
37.0
40.4
2.25
22
292
(3048689) Calprotectin [Mass/mass] in Stool
7
42
1.81
0.73
1.3
1.6
ug/g
92.9
106.3
—
7
34
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
28
1.90
0.69
1.4
2.1
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
15
108
1.64
0.67
2.5
2.8
u/l
24.3
29.1
0.72
15
101
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
19
0.00
0.62
0.0
1.1
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
19
0.00
0.62
0.0
1.2
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
6
35
1.84
0.61
1.0
1.4
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
33
300
1.76
0.53
22.7
12.4
%
37.9
39.7
1.26
26
217
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
16
0.00
0.42
0.0
1.2
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
21
178
1.40
0.39
3.1
2.8
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
29
263
1.43
0.34
33.6
13.8
%
13.8
13.6
0.53
29
257
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
7
54
1.36
0.33
1.6
1.3
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
31
325
0.75
0.32
3.9
4.8
mmol/l
5.7
5.9
0.93
26
300
(3013826) Glucose [Moles/volume] in Serum or Plasma
20
172
1.34
0.31
7.0
3.9
mmol/l
6.6
6.7
0.09
20
157
(3013512) EKG study
11
86
1.39
0.30
3.6
3.6
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
13
105
1.36
0.30
1.4
2.0
u/l
95.8
115.0
0.25
13
99
(3041096) Erythrocytes [Presence] in Urine by Automated
11
87
1.37
0.28
3.9
3.7
—
—
—
0
0
(3020891) Body temperature
0
11
0.00
0.22
0.0
3.3
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
0
11
0.00
0.22
0.0
3.6
—
1.2
—
0
11
(40768443) Skin Pathology biopsy report
0
10
0.00
0.22
0.0
1.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(1002224) Polysomnography panel
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
6
74
0.78
0.17
1.3
1.2
g/l
2.0
2.4
—
6
40
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
9
78
1.20
0.17
1.4
1.8
mg/l
3.6
0.7
—
9
69
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
29
301
0.85
0.17
4.6
5.0
mu/l
2.0
1.9
0.13
24
276
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
13
116
1.18
0.11
3.5
4.0
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
12
134
0.85
0.11
2.6
2.3
nmol/l
74.7
78.8
0.19
12
119
(3044889) 12 lead EKG panel
24
229
1.13
0.06
4.0
3.6
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
10
110
0.88
0.06
1.9
3.0
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
10
95
1.07
0.00
4.4
2.9
—
—
—
0
0
(3015736) pH of Urine
11
108
1.03
0.00
2.5
3.6
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
2.3
—
4.0
—
0
6
(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
8
83
0.95
0.00
1.4
2.3
umol/l
30991.3
11073.0
—
8
70
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
2.3
—
106.2
—
0
6
(3022313) Gas panel - Capillary blood
0
6
0.00
0.00
0.0
6.7
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
7
0.00
0.00
0.0
3.1
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
0
7
0.00
0.00
0.0
2.4
—
1.4
—
0
7
(3038515) Glucose [Moles/volume] in Venous blood
0
7
0.00
0.00
0.0
2.4
—
8.3
—
0
7
(4027681)
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
6
64
0.93
0.00
2.7
3.4
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
7
0.00
0.00
0.0
5.0
—
25.1
—
0
7
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.1
—
66.8
—
0
9
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
5
58
0.84
0.00
1.2
1.4
—
675.6
—
0
18
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_COLORECTAL_SQUAM_EXALLC – Colorectal squamous cell carcinoma, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).