info icon

This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_COLORECTAL_SQUAM_EXALLC for full statistics.

Colorectal squamous cell carcinoma

C3_COLORECTAL_SQUAM

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C1[8-9]|C20
  • Cancer registry: Morphology ICD-O-3 8070
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

38

4. Check minimum number of events

None

38

5. Include endpoints

None

38

6. Filter based on genotype QC (FinnGen only)

38

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF9

Similar endpoints

List of similar endpoints to Colorectal squamous cell carcinoma based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 38 31 7
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 62.06 59.94 71.42

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
28
43
21.94
20.83
3.4
5.5
ug/l
2.1
12.0
1.17
23
37
(3022145) Colonoscopy Study observation
25
38
17.31
18.36
2.8
1.1
—
—
—
0
0
(4035726)
18
28
11.31
12.35
1.4
1.2
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
29
140
5.50
5.50
9.0
5.4
g/l
35.3
35.1
0.09
29
132
(3012095) Magnesium [Moles/volume] in Serum or Plasma
17
54
4.89
5.27
2.3
2.8
mmol/l
0.8
0.8
0.81
17
49
(3023368) Bacteria identified in Blood by Culture
20
77
4.37
4.78
6.3
4.8
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
28
144
4.59
4.39
3.5
1.8
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
22
113
3.25
3.10
8.4
4.6
mmol/l
2.3
2.3
0.30
22
97
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
9
23
4.79
3.00
1.2
1.4
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
7
14
5.86
2.88
6.1
5.5
mmol/l
24.7
25.8
—
7
14
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
16
71
3.17
2.83
2.6
2.0
—
—
—
0
0
(40758558) Short blood count panel - Blood
18
86
3.08
2.81
10.1
9.5
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
21
112
2.96
2.67
3.6
3.0
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
13
55
3.07
2.45
2.5
2.8
e6/l
2.7
4.1
—
7
30
(3033658) Prothrombin time (PT) actual/Normal
17
84
2.85
2.44
3.2
3.9
%
101.1
93.0
0.60
17
84
(3002256) Pathology report gross observation
11
42
3.28
2.44
2.0
1.2
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
29
202
2.83
2.21
11.4
7.4
umol/l
8.0
9.8
2.02
29
189
(3025941) Bacteria identified in Stool by Culture
6
15
4.53
2.13
1.0
1.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
30
214
2.90
2.05
5.6
4.3
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
23
142
2.57
2.04
5.8
4.2
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
5
11
5.05
2.00
6.0
9.9
%
0.9
1.4
—
5
11
(3014007) Fractional oxyhemoglobin in Arterial blood
5
11
5.05
2.00
6.0
10.3
%
97.4
94.7
—
5
11
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
5
11
5.05
2.00
6.0
9.9
%
0.4
0.8
—
5
11
(3044640) Blood type and Crossmatch panel - Blood
17
94
2.46
1.87
3.1
2.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
17
95
2.43
1.82
3.7
3.0
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
5
14
3.94
1.67
1.0
1.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
20
124
2.29
1.66
5.7
6.8
inr
1.0
1.2
—
5
39
(42870588) Differential panel, method unspecified - Blood
18
108
2.27
1.60
5.0
5.4
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
12
60
2.46
1.59
5.0
3.9
mmol/l
2.5
2.5
0.18
12
49
(3000492) Spirometry study
6
22
3.04
1.50
1.0
1.7
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
5
16
3.43
1.49
9.4
9.2
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
23
157
2.18
1.46
3.4
5.7
e9/l
0.5
0.6
0.04
17
144
(3006315) Basophils [#/volume] in Blood
23
157
2.18
1.46
3.5
5.8
e9/l
0.0
0.0
1.44
17
144
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
12
63
2.32
1.42
2.1
2.6
e6/l
0.2
1.0
—
6
38
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
13
71
2.26
1.41
1.9
1.3
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
5
17
3.22
1.40
1.8
1.6
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
23
160
2.11
1.35
3.8
5.9
e9/l
1.3
1.8
2.37
18
148
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
5
18
3.04
1.33
2.4
1.5
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
19
124
2.06
1.31
2.2
1.9
pmol/l
87.1
99.5
—
10
51
(3002173) Hemoglobin [Mass/volume] in Arterial blood
6
25
2.65
1.30
8.3
8.0
g/l
112.7
119.0
—
6
25
(3000991) Gas panel - Venous blood
5
19
2.87
1.25
6.4
8.1
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
19
2.87
1.25
1.6
2.2
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
23
164
2.02
1.22
4.3
5.8
e9/l
0.2
0.2
0.37
18
150
(3021589) Normoblasts [#/volume] in Blood
19
127
1.99
1.21
17.2
10.7
e9/l
0.0
0.0
0.00
13
102
(3007853) Bacteria identified in Skin by Aerobe culture
7
30
2.63
1.20
1.3
1.5
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
7
33
2.37
1.12
1.3
1.7
ug/g
92.9
96.8
—
7
26
(46235355) HIV 1 and 2 tests - Meaningful Use set
7
34
2.29
1.09
1.1
1.6
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
6
27
2.44
0.98
8.3
7.6
%
98.3
95.6
—
6
27
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
16
107
1.86
0.97
4.7
2.6
u/l
57.4
54.9
0.12
16
98
(21494755) Public health laboratory ask at order entry panel
6
29
2.26
0.94
1.0
1.3
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
27
0.00
0.81
0.0
1.1
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
9
58
1.72
0.77
2.8
1.6
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
11
71
1.77
0.72
1.3
1.3
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
27
308
0.57
0.68
3.7
5.8
mmol/mol
37.0
39.9
1.81
22
286
(40760892) CBC W Ordered Manual Differential panel - Blood
10
64
1.76
0.66
4.6
4.9
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
7
45
1.68
0.53
1.7
1.5
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
7
45
1.68
0.53
1.7
1.5
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
31
1.70
0.45
1.4
2.1
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
16
0.00
0.42
0.0
1.2
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
9
68
1.42
0.42
1.4
1.7
mg/l
3.6
0.8
—
9
58
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
18
0.00
0.41
0.0
1.0
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
18
0.00
0.41
0.0
1.2
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
33
301
1.73
0.40
22.7
15.3
%
37.9
39.6
1.29
26
219
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
13
101
1.44
0.38
1.4
2.1
u/l
95.8
112.7
0.21
13
96
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
15
121
1.40
0.36
2.5
3.5
u/l
24.3
29.8
0.88
15
113
(3002385) Erythrocyte distribution width [Ratio]
29
266
1.38
0.34
33.6
18.2
%
13.8
13.7
0.17
29
261
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
21
181
1.36
0.33
3.1
2.7
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
31
324
0.77
0.31
3.9
4.6
mmol/l
5.7
5.8
0.47
26
299
(3041096) Erythrocytes [Presence] in Urine by Automated
11
86
1.39
0.30
3.9
3.6
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
29
305
0.79
0.28
4.6
4.8
mu/l
2.0
1.8
0.30
24
276
(3015171) Extractable nuclear Ab [Units/volume] in Serum
0
11
0.00
0.22
0.0
1.3
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
11
0.00
0.22
0.0
1.4
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
0
11
0.00
0.22
0.0
1.7
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
10
0.00
0.22
0.0
4.4
—
24.6
—
0
10
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
10
0.00
0.22
0.0
1.8
—
93.3
—
0
10
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
0
10
0.00
0.22
0.0
2.6
—
—
—
0
0
(3020891) Body temperature
0
10
0.00
0.22
0.0
4.1
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
10
0.00
0.22
0.0
1.3
—
—
—
0
0
(3022313) Gas panel - Capillary blood
0
10
0.00
0.22
0.0
4.4
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3013512) EKG study
11
91
1.29
0.20
3.6
3.5
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
7
59
1.23
0.19
1.6
1.3
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
20
181
1.22
0.17
6.9
4.5
mmol/l
6.6
6.5
0.04
20
171
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
13
115
1.20
0.13
3.5
4.0
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
12
134
0.85
0.11
2.6
2.3
nmol/l
74.7
76.0
0.05
12
119
(3011397) Hemoglobin [Presence] in Urine by Test strip
6
69
0.85
0.08
2.7
3.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
10
109
0.89
0.04
1.9
3.0
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
10
106
0.92
0.01
4.4
2.7
—
—
—
0
0
(3015736) pH of Urine
11
113
0.96
0.00
2.5
3.4
—
—
—
0
0
(3044889) 12 lead EKG panel
24
237
1.03
0.00
4.0
3.9
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
5.5
—
0
6
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3001788) Aldosterone [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
283.2
—
0
6
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
6
65
0.91
0.00
1.3
1.4
g/l
2.0
2.3
—
6
34
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
0
7
0.00
0.00
0.0
4.7
—
1.8
—
0
7
(3026493) Urate [Moles/volume] in Serum or Plasma
8
85
0.93
0.00
1.4
2.4
umol/l
30991.3
6172.9
—
8
70
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(1002224) Polysomnography panel
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
5
51
0.98
0.00
1.2
1.4
—
805.0
—
0
16
(40760888) Immunoglobulin light chains.free panel - Serum
0
7
0.00
0.00
0.0
3.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_COLORECTAL_SQUAM – Colorectal squamous cell carcinoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).