info icon

Liveborn infants according to place of birth

Z21_LIVEB_INFANTS_ACCOR_PLACE_BIRTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Z38
  • Cause of death: ICD-10 Z38

2 out of 7 registries used, show all original rules.

302

4. Check minimum number of events

None

302

5. Include endpoints

None

302

6. Filter based on genotype QC (FinnGen only)

275

Control definitions (FinnGen only)

Control exclude
Z21_PERSONS_ENCOUNTERI_HEALTH_SERVI_CIRCUMSTANC_RELATED_REPRODUCTION

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 275 275 -
Unadjusted period prevalence (%) 0.11 0.11 -
Median age at first event (years) 0.01 0.01 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
251
Matched controls
2465
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z38.0
ICD-10 Finland
Singleton, born in hospital
9767.4
255.9
202
*
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
+∞
66.3
61
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
800.0
65.6
62
*
Z37.0
ICD-10 Finland
Single live birth
+∞
65.1
60
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
61.1
64.9
75
17
SPAT1380
SPAT
Postpartum check-up
35.8
59.2
77
30
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
43.4
58.9
73
23
SPAT1197
SPAT
Extensive health check-up of expecting family
25.4
56.9
82
46
W78
ICPC
Pregnancy
16.3
52.8
91
83
MA3AE
NOMESCO Finland
Combined first trimester screening
606.0
52.1
50
*
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
+∞
51.6
48
*
SPAT1379
SPAT
Health check-up of pregnant person
20.1
50.0
78
54
O80.0
ICD-10 Finland
Spontaneous vertex delivery
17.3
48.8
81
66
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
33.3
47.1
62
24
WX307
NOMESCO Finland
Obstetric epidural analgesia
50.1
46.7
56
14
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
39.8
45.3
57
18
Z39.2
ICD-10 Finland
Routine postpartum follow-up
28.5
45.1
62
28
MAX99
NOMESCO Finland
Assistance to normal delivery
25.2
44.8
64
33
Z32.1
ICD-10 Finland
Pregnancy confirmed
22.6
40.0
59
33
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
212.1
36.6
37
*
Z3232
NOMESCO Finland
Midwife
33.1
35.9
47
17
Z38.3
ICD-10 Finland
Twin, born in hospital
+∞
32.8
31
*
Z34
ICD-10 Finland
Supervision of normal pregnancy
44.0
28.7
35
9
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
30.8
25.0
33
12
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
11.3
24.3
47
49
TMA00
NOMESCO Finland
Episiotomy
247.6
22.9
23
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
+∞
22.1
21
*
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
27.9
20.8
28
11
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
41.2
18.7
23
6
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
20.2
17.6
26
14
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
20.8
17.1
25
13
O99.80
ICD-10 Finland
The fear of childbirth
42.5
16.5
20
5
W90
ICPC
Uncompl labour/delivery livebirth
11.3
13.9
26
25
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
78.2
13.6
15
*
W85
ICPC
Gestational diabetes
25.4
12.5
17
7
W29
ICPC
Pregnancy symptom/complaint other
15.1
12.4
20
14
Z31.5
ICD-10 Finland
Genetic counselling
+∞
11.5
11
*
O48
ICD-10 Finland
Prolonged pregnancy
29.0
10.7
14
5
Z38.1
ICD-10 Finland
Singleton, born outside hospital
+∞
10.4
10
*
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
+∞
10.4
10
*
SPAT1195
SPAT
Antenatal classes
12.6
10.4
18
15
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
15.6
9.5
15
10
Z36.8
ICD-10 Finland
Other antenatal screening
+∞
9.4
9
*
MAE00
NOMESCO Finland
Outlet vacuum delivery
22.3
9.4
13
6
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
37.5
9.0
11
*
OAA11
SPAT
NA
13.0
8.9
15
12
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
50.9
8.7
10
*
O32.1
ICD-10 Finland
Maternal care for breech presentation
50.9
8.7
10
*
P07.3
ICD-10 Finland
Other preterm infants
5.5
8.6
25
49
O81.4
ICD-10 Finland
Vacuum extractor delivery
16.7
8.6
13
8
XMA22
NOMESCO Finland
General examination of pregnant woman
28.1
8.5
11
*
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
91.4
8.4
9
*
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
+∞
8.3
8
*
Z32
ICD-10 Finland
Pregnancy examination and test
+∞
8.3
8
*
SPAT1196
SPAT
Monitoring of normal pregnancy
6.3
8.2
21
35
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.2
8.1
133
844
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
22.5
8.0
11
5
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.4
7.6
22
43
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
81.0
7.4
8
*
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
+∞
7.3
7
*
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
30.4
7.1
9
*
ZXE00
NOMESCO Finland
One hour or less
2.1
6.9
95
547
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
17.0
6.7
10
6
R2110
NOMESCO Finland
Giving the first information
4.8
6.7
21
46
SPAT1189
SPAT
Other ultrasound examination during pregnancy
8.9
6.6
13
15
TQW30
NOMESCO Finland
Acupuncture
+∞
6.2
6
*
ZXD05
NOMESCO Finland
Urgent procedure
2.4
6.1
54
251

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_LIVEB_INFANTS_ACCOR_PLACE_BIRTH – Liveborn infants according to place of birth

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).