Vascular dementia (multiple infarctions)

VD_MI

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F01.1
  • Hospital discharge: ICD-9 4378
  • Cause of death: ICD-10 F01.1
  • Cause of death: ICD-9 4378

2 out of 7 registries used, show all original rules.

632

4. Check minimum number of events

None

632

5. Include endpoints

None

632

6. Filter based on genotype QC (FinnGen only)

632

Control definitions (FinnGen only)

Control exclude
F5_DEMENTIA, G6_ALZHEIMER, G6_AD_WIDE

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F01
Name in latin
Dementia e multis infarctibus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17740 8997 8189
Only index persons 5236 2717 2519
Unadjusted period prevalence (%)
Whole population 0.25 0.26 0.23
Only index persons 0.10 0.10 0.10
Median age at first event (years)
Whole population 79.25 80.73 77.74
Only index persons 80.26 82.38 77.98

-FinnGen-

Key figures

All Female Male
Number of individuals 632 186 446
Unadjusted period prevalence (%) 0.16 0.06 0.20
Median age at first event (years) 76.77 78.54 76.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
584
Matched controls
5840
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
+∞
262.8
232
*
F01.10
ICD-10 Finland
Multi-infarct dementia without additional symptoms
2576.8
191.5
175
*
F01.1
ICD-10 Finland
Multi-infarct dementia
2362.9
180.9
166
*
F01.9
ICD-10 Finland
Vascular dementia, unspecified
222.4
137.1
137
8
F03
ICD-10 Finland
Unspecified dementia
81.9
133.7
148
24
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
7.9
84.4
225
428
N06DX01
ATC
memantine; oral
104.0
75.1
81
9
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
69.1
65
*
N06DA02
ATC
donepezil; oral
121.3
61.2
65
6
N05AX08
ATC
risperidone; systemic
10.5
55.8
115
133
4378A
ICD-9 Finland
Other and ill-defined cerebrovascular disease, Other[MULTI-INFARKTIDEMENTIA]
+∞
52.9
50
*
G30.1
ICD-10 Finland
Alzheimer disease with late onset
56.4
51.9
61
12
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
4.5
49.6
220
695
N05AH04
ATC
quetiapine; oral
7.2
46.5
122
206
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
101.8
43.4
47
5
F01.0
ICD-10 Finland
Vascular dementia of acute onset
+∞
43.2
41
*
N06DA03
ATC
rivastigmine; oral, transdermal
112.7
39.2
42
*
4378X
ICD-9 Finland
Other and ill-defined cerebrovascular disease, Other[MORBUS CERBROVASCULARIS ALIA DEFINITA]
+∞
36.8
35
*
F01.14
ICD-10 Finland
Multi-infarct dementia's other mixed symptoms of mixed type
+∞
36.8
35
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
6.3
30.7
86
155
N03AG01
ATC
valproic acid; systemic, rectal
10.9
27.8
54
54
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
39.9
27.4
34
9
G30.8
ICD-10 Finland
Other Alzheimer disease
65.1
27.2
31
5
N05AD03
ATC
melperone; systemic
9.0
25.9
56
68
B01AC07
ATC
dipyridamole; systemic
3.5
25.9
140
485
N06AB04
ATC
citalopram; systemic
3.0
23.6
163
668
N06DA04
ATC
galantamine; oral
46.9
22.5
27
6
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
46.9
22.5
27
6
R41.0
ICD-10 Finland
Disorientation, unspecified
6.8
22.1
57
91
F01.11
ICD-10 Finland
The other additional symptoms of multi-infarct dementia, mainly paranoidism
+∞
20.9
20
*
N05AD01
ATC
haloperidol; systemic
5.4
20.6
64
130
Z75.5
ICD-10 Finland
Holiday relief care
9.9
19.9
40
43
G40.9
ICD-10 Finland
Epilepsy, unspecified
7.5
19.7
47
67
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.3
19.2
106
367
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
45.5
18.3
22
5
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
5.1
18.3
59
125
2900A
ICD-9 Finland
Senile and presenile organic psychotic conditions, Senile dementia, uncomplicated
+∞
17.8
17
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.8
17.2
49
90
F01.12
ICD-10 Finland
The other additional symptoms of multi-infarct dementia, mainly hallucinations
+∞
16.7
16
*
P70
ICPC
Dementia
11.2
15.6
29
27
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.5
15.4
75
234
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
14.6
252
1577
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
76.8
13.6
15
*
F01.13
ICD-10 Finland
The other additional symptoms of multi-infarct dementia, mainly depression
+∞
12.5
12
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.5
12.5
44
103
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
132.4
12.5
13
*
R53
ICD-10 Finland
Malaise and fatigue
2.2
12.2
140
727
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
6.1
11.9
32
55
N03AF02
ATC
oxcarbazepine; oral
6.9
11.9
29
44
F01.3
ICD-10 Finland
Mixed cortical and subcortical vascular dementia
+∞
11.5
11
*
F0019, G301
ICD-10 Finland
NA
+∞
11.5
11
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.7
11.4
81
328
F01
ICD-10 Finland
Vascular dementia
44.1
10.9
13
*
F05.1
ICD-10 Finland
Delirium superimposed on dementia
21.9
10.7
15
7
F01.2
ICD-10 Finland
Subcortical vascular dementia
61.0
10.6
12
*
N05AH03
ATC
olanzapine; systemic
7.0
10.5
25
37
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
3.5
10.2
48
147
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
10.1
196
1238
P20
ICPC
Memory disturbance
2.5
10.0
82
359
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.8
10.0
22
29
Z2445
NOMESCO Finland
Psychologist
8.9
9.8
20
23
N05BA06
ATC
lorazepam; systemic, sublingual
3.3
9.8
48
152
130
Kela drug reimbursment
Malignant tumour
0.1
9.7
6
387
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
55.8
9.7
11
*
N05BA04
ATC
oxazepam; oral
2.0
9.5
137
772
A06AD11
ATC
lactulose; oral
1.9
9.1
163
998
F10.20
ICD-10 Finland
Alcohol dependence currently independent
24.4
8.9
12
5
N06AX11
ATC
mirtazapine; oral
1.9
8.9
140
817
F05.9
ICD-10 Finland
Delirium, unspecified
4.7
8.9
29
64
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
8.8
29
746
F009, G309
ICD-10 Finland
NA
+∞
8.3
8
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
8.0
107
583
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
3.1
7.8
42
143
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
4.1
7.7
29
74
AA1AD
NOMESCO Finland
CT of head and brain
1.9
7.7
132
786
4019X
ICD-9 Finland
Essential hypertension, Unspecified
2.4
7.5
63
280
G30
ICD-10 Finland
Alzheimer disease
80.9
7.4
8
*
S01.0
ICD-10 Finland
Open wound of scalp
2.6
7.3
51
205
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.8
7.2
29
79
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.7
7.1
47
184
A98
ICPC
Health maint/preventive medicine
0.6
7.0
191
2567
A10AE04
ATC
insulin glargine; parenteral
2.5
6.9
52
219
SPAT1053
SPAT
Memory test
2.0
6.8
91
494
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.0
6.7
38
133
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.3
6.6
60
275
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
3.0
6.5
37
130
N06AB10
ATC
escitalopram; oral
2.3
6.5
57
258
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
6.4
97
552
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
14.5
6.4
10
7
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.0
6.4
78
408
L15
ICPC
Knee symptom/complaint
0.3
6.3
12
398
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.3
6.3
29
90
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
2.8
6.1
36
132
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
12.7
6.1
10
8
315
Kela drug reimbursment
Clopidogrel
4.2
6.0
21
51
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
5.6
6.0
16
29

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(40768804) Tissue Pathology biopsy report
50
1058
0.43
8.02
1.7
2.5
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
171
2407
0.60
7.32
4.3
4.5
mmol/l
3.8
4.2
4.78
157
2126
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
181
2510
0.61
7.27
4.8
5.1
mmol/l
2.1
2.4
4.25
168
2188
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
184
2533
0.61
7.12
4.7
5.1
mmol/l
6.3
6.2
0.24
156
2190
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
174
2424
0.61
7.06
22.9
19.7
ml/min/173m2
66.3
64.9
0.35
141
2037
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
170
2374
0.61
6.92
4.2
4.5
mmol/l
1.3
1.4
2.52
156
2064
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
169
2294
0.64
5.75
3.9
4.1
mmol/l
1.2
1.2
0.15
154
1984
(3002385) Erythrocyte distribution width [Ratio]
152
2106
0.63
5.64
30.2
23.9
%
14.5
14.2
1.59
146
2038
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
186
2454
0.66
5.44
7.9
6.7
mmol/mol
46.2
42.2
2.86
166
2188
(3021589) Normoblasts [#/volume] in Blood
74
1210
0.56
5.28
11.7
10.8
e9/l
0.0
0.0
0.72
60
970
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
218
2775
0.67
5.27
10.7
10.5
u/l
28.5
24.3
0.48
201
2623
(3044889) 12 lead EKG panel
142
1954
0.65
4.95
4.8
4.7
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
219
2718
0.70
4.28
24.7
19.1
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
103
1474
0.64
4.18
4.3
5.7
ug/l
2.4
8.3
1.28
83
1270
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
25
543
0.44
4.18
4.0
2.6
%
20.5
21.2
0.11
20
474
(3013707) Erythrocyte sedimentation rate by Westergren method
154
2028
0.68
4.14
3.6
4.0
mm/h
18.5
17.1
0.35
136
1817
(1761868) Lipid panel - Serum or Plasma
32
627
0.48
4.04
4.7
3.5
—
—
—
0
0
(3022948) Iron [Moles/volume] in Serum or Plasma
32
624
0.49
3.99
3.4
2.5
umol/l
10.6
11.5
0.53
27
573
(3002256) Pathology report gross observation
15
385
0.37
3.74
1.5
1.5
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
49
818
0.56
3.69
3.0
3.3
ug/l
0.9
1.0
0.34
36
581
(3010813) Leukocytes [#/volume] in Blood
240
2887
0.73
3.68
34.8
28.6
e9/l
7.7
7.2
1.91
219
2757
(42870588) Differential panel, method unspecified - Blood
62
971
0.60
3.66
3.9
4.8
—
—
—
0
0
(3024731) MCV [Entitic volume]
240
2885
0.73
3.65
34.7
28.4
fl
91.8
92.2
0.51
223
2793
(3035941) MCH [Entitic mass]
240
2885
0.73
3.65
34.6
28.4
pg
30.3
30.4
0.41
223
2791
(3026361) Erythrocytes [#/volume] in Blood
240
2885
0.73
3.65
34.7
28.5
e12/l
4.2
4.3
0.87
218
2759
(3007461) Platelets [#/volume] in Blood
240
2884
0.73
3.64
34.9
28.5
e9/l
240.3
230.1
1.37
223
2767
(3023103) Potassium [Moles/volume] in Serum or Plasma
238
2858
0.73
3.57
30.8
24.2
mmol/l
4.0
4.0
2.04
218
2745
(3019550) Sodium [Moles/volume] in Serum or Plasma
238
2856
0.73
3.54
30.9
24.1
mmol/l
139.7
139.3
1.27
220
2743
(3000963) Hemoglobin [Mass/volume] in Blood
241
2885
0.73
3.52
34.9
28.8
g/l
126.9
128.9
1.11
225
2793
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
61
375
1.69
3.46
2.8
2.7
ug/l
4.3
6.5
1.38
51
320
(3012516) Albumin [Mass/volume] in Urine
60
926
0.61
3.33
3.0
3.1
mg/l
48.7
346.3
1.75
44
623
(3019309) Folate [Moles/volume] in Red Blood Cells
114
823
1.47
3.24
2.0
1.8
nmol/l
1009.6
1183.8
1.47
91
613
(3019069) Monocytes/100 leukocytes in Blood
94
1298
0.67
3.11
4.7
5.3
%
8.9
9.1
0.27
86
1197
(3009508) Creatinine [Moles/volume] in Urine
62
932
0.63
3.07
2.8
3.1
mmol/l
7.0
6.6
0.32
45
760
(3013115) Eosinophils [#/volume] in Blood
105
1417
0.69
3.07
4.4
4.9
e9/l
0.2
0.2
0.48
90
1222
(3006504) Eosinophils/100 leukocytes in Blood
94
1294
0.68
3.05
4.6
5.0
%
2.8
2.8
0.03
85
1187
(3002030) Lymphocytes/100 leukocytes in Blood
97
1324
0.68
3.01
4.8
5.4
%
21.0
23.8
1.69
89
1212
(3000492) Spirometry study
6
195
0.30
2.98
1.5
1.6
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
84
1170
0.67
2.89
4.7
4.8
%
22.9
22.5
0.10
46
626
(3044290) Cell count panel - Cerebral spinal fluid
9
22
4.13
2.88
1.2
1.0
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
7
13
5.42
2.87
1.1
1.2
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
37
618
0.57
2.80
2.4
1.6
mg/l
1.0
1.4
1.35
30
489
(3022096) Basophils/100 leukocytes in Blood
93
1258
0.69
2.73
4.4
5.0
%
0.5
0.6
0.89
85
1155
(3018010) Neutrophils/100 leukocytes in Blood
96
1289
0.70
2.70
5.2
5.2
%
63.9
60.3
1.93
88
1189
(3001604) Monocytes [#/volume] in Blood
102
1355
0.70
2.70
4.4
4.8
e9/l
0.6
0.6
0.29
88
1143
(3020682) Albumin/Creatinine [Ratio] in Urine
70
990
0.67
2.59
3.5
3.9
mg/mmol
15.0
11.7
0.30
44
648
(3001122) Ferritin [Mass/volume] in Serum or Plasma
89
1203
0.70
2.59
2.8
2.8
ug/l
141.2
165.3
0.53
77
1076
(3030467) Casts [#/volume] in Urine by Automated count
72
1010
0.67
2.56
4.6
3.8
e6/l
0.8
0.5
0.32
64
812
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
196
2336
0.76
2.50
4.3
4.4
mu/l
2.0
2.1
0.58
178
2024
(3013650) Neutrophils [#/volume] in Blood by Automated count
127
1602
0.74
2.41
6.1
7.9
e9/l
5.3
4.5
1.81
106
1383
(3006315) Basophils [#/volume] in Blood
105
1364
0.72
2.41
4.5
4.8
e9/l
0.0
0.0
0.38
89
1155
(36304419) Bacteria [Presence] in Urine
68
950
0.68
2.36
4.6
3.8
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
151
1848
0.76
2.31
3.3
3.5
pmol/l
14.7
15.2
1.55
129
1611
(40768797) Stomach Pathology biopsy report
17
338
0.49
2.30
1.1
1.3
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
192
2276
0.77
2.30
6.3
6.9
u/l
85.0
86.3
0.12
171
2098
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
6
165
0.36
2.17
5.7
2.2
—
—
—
0
0
(3018418) pH of Serum or Plasma
75
1013
0.70
2.16
4.0
3.7
ph
7.4
7.4
—
9
200
(40758558) Short blood count panel - Blood
48
705
0.65
2.15
5.5
5.9
—
—
—
0
0
(3027945) Reticulocytes/100 erythrocytes in Blood
31
500
0.60
2.09
2.5
2.2
%
1.8
1.8
0.04
24
447
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
239
2732
0.80
2.05
26.0
19.9
mg/l
32.5
30.1
0.47
212
2327
(3022145) Colonoscopy Study observation
11
243
0.44
2.01
1.6
1.2
—
—
—
0
0
(4035726)
11
242
0.44
1.99
1.2
1.4
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
63
861
0.70
1.95
2.0
1.7
nmol/l
17.4
19.6
0.45
55
735
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
5
11
4.56
1.94
1.2
1.0
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
5
11
4.56
1.94
1.2
1.0
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
109
1359
0.76
1.87
2.8
3.5
ng/l
1921.1
2867.6
1.54
92
1200
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
9
200
0.44
1.86
1.2
1.3
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
36
230
1.60
1.85
1.6
1.5
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
61
829
0.71
1.83
2.5
2.9
umol/l
7034.7
8027.2
0.05
48
677
(40761536) Microorganisms panel - Urine sediment
14
272
0.50
1.81
8.0
4.6
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
21
357
0.57
1.76
1.6
2.7
umol/l
6.8
12.1
1.41
15
303
(3019198) Lymphocytes [#/volume] in Blood
113
1390
0.77
1.74
4.7
5.1
e9/l
1.5
1.7
1.66
94
1203
(46235355) HIV 1 and 2 tests - Meaningful Use set
11
228
0.47
1.72
1.9
1.4
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
15
279
0.53
1.71
1.5
1.4
—
—
—
0
0
(4094501)
0
49
0.00
1.69
0.0
1.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
197
2263
0.81
1.68
25.7
21.2
%
33.8
36.5
1.16
87
1291
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
136
1624
0.79
1.64
4.3
5.4
umol/l
11.1
13.7
2.22
123
1529
(3013512) EKG study
76
977
0.75
1.61
5.4
4.6
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
59
784
0.73
1.56
6.4
4.5
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
91
1132
0.77
1.53
4.2
3.8
e6/l
28.8
148.1
1.46
80
925
(21494434) Karyotype in Bone marrow
0
44
0.00
1.51
0.0
1.1
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
120
985
1.27
1.51
2.5
2.0
u/l
260.3
253.0
0.04
109
909
(3027273) Bicarbonate [Moles/volume] in Venous blood
32
210
1.55
1.50
4.7
3.1
mmol/l
24.7
24.9
0.11
32
202
(3043409) Potassium [Moles/volume] in Arterial blood
20
116
1.75
1.49
3.2
3.3
mmol/l
4.0
4.1
0.06
20
102
(3033705) Calcium.ionized [Moles/volume] in Venous blood
15
80
1.89
1.45
2.7
2.4
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
22
134
1.66
1.40
2.0
1.7
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
37
522
0.69
1.40
4.6
4.4
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
25
382
0.64
1.40
1.2
1.3
g/l
2.2
2.7
1.16
18
220
(3018095) Leukocytes [#/volume] in Urine
103
1247
0.79
1.39
4.5
4.3
e6/l
271.9
174.0
0.25
82
978
(3026008) Bacteria identified in Urine by Culture
138
1165
1.23
1.36
3.8
3.8
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
126
1487
0.81
1.35
6.8
5.4
mmol/l
1.2
1.2
1.50
107
1295
(3039443) Prostate specific Ag panel - Serum or Plasma
0
37
0.00
1.34
0.0
1.6
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
38
0.00
1.34
0.0
1.2
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
21
330
0.62
1.33
4.3
4.8
%
33.6
33.5
0.01
16
205
(4010399)
9
172
0.52
1.31
1.8
1.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
45
600
0.73
1.24
1.3
1.2
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
67
843
0.77
1.24
3.5
3.1
e6/l
4.6
4.4
0.05
58
749
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
10
187
0.53
1.21
1.3
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
23
148
1.57
1.21
1.9
2.0
u/ml
0.3
0.4
0.58
16
83
(3013139) Helicobacter pylori Ag [Presence] in Stool
6
126
0.47
1.18
1.2
1.3
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
19
295
0.63
1.17
6.4
3.8
mmol/l
1.2
1.2
0.40
14
251
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
34
0.00
1.16
0.0
1.6
—
2.5
—
0
27
(3023368) Bacteria identified in Blood by Culture
132
1136
1.20
1.08
4.7
4.4
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
110
1282
0.83
1.04
4.2
3.8
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
5
22
2.28
1.03
1.2
1.5
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
47
362
1.32
1.00
15.5
9.6
—
—
—
0
0
(4024509)
5
23
2.18
0.98
1.2
1.7
—
—
—
0
0
(3008898) HLA-B27 [Presence]
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
(4146454)
0
29
0.00
0.98
0.0
3.1
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
30
0.00
0.97
0.0
3.8
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
12
198
0.60
0.97
2.3
2.7
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
0
32
0.00
0.95
0.0
1.1
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
12
196
0.60
0.94
1.8
1.4
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
6
28
2.15
0.91
6.8
25.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
117
1338
0.84
0.90
3.9
4.8
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
26
185
1.42
0.90
3.5
2.4
%
0.8
0.7
0.67
26
180
(3026782) Osmolality of Urine
68
817
0.81
0.88
4.4
3.3
mosm/kgh2o
628.2
547.2
2.07
51
701
(3025941) Bacteria identified in Stool by Culture
8
140
0.57
0.83
1.5
1.3
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
24
0.00
0.79
0.0
3.4
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay
0
25
0.00
0.79
0.0
1.0
—
5.1
—
0
5
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
25
0.00
0.79
0.0
3.2
—
10.2
—
0
25
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
147
1633
0.87
0.78
7.1
6.0
mmol/l
1.2
1.2
0.50
120
1316
(3017569) Oxygen content in Arterial blood
0
26
0.00
0.78
0.0
4.2
—
—
—
0
0
(40768443) Skin Pathology biopsy report
7
125
0.55
0.78
1.9
1.3
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
28
0.00
0.76
0.0
1.3
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
16
230
0.69
0.74
1.6
1.6
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
7
38
1.85
0.73
6.3
4.5
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
40
497
0.79
0.72
1.7
1.9
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
21
153
1.38
0.67
2.2
1.9
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
47
385
1.24
0.67
3.8
3.6
mmol/l
2.2
2.0
0.09
39
295
(3007853) Bacteria identified in Skin by Aerobe culture
46
376
1.24
0.66
1.6
1.8
—
—
—
0
0
(3014271) Vancomycin [Susceptibility]
5
28
1.79
0.66
5.4
3.1
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
190
2053
0.89
0.65
5.6
4.8
—
—
—
0
0
(3020876) Protein [Mass/time] in 24 hour Urine
5
29
1.73
0.64
1.8
1.9
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
39
477
0.80
0.63
6.2
4.7
mmol/l
1.1
1.1
0.02
33
440
(3017143) Hepatitis C virus Ab [Presence] in Serum
12
176
0.67
0.63
1.5
1.4
—
—
—
0
0
(3022621) pH of Urine by Test strip
28
217
1.30
0.62
3.9
3.8
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
97
1090
0.87
0.62
2.3
2.1
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
20
0.00
0.60
0.0
1.5
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
(3017704) Immunofixation for Urine
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
0
22
0.00
0.59
0.0
2.5
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
54
456
1.20
0.59
5.8
5.7
mmol/l
1.2
1.3
0.04
35
327
(3000919) Neutrophils/100 leukocytes in Pleural fluid
0
23
0.00
0.58
0.0
1.3
—
22.6
—
0
17
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
(3010144) Erythrocytes [#/volume] in Synovial fluid
0
23
0.00
0.58
0.0
1.2
—
334242.1
—
0
17
(3003338) MCHC [Mass/volume]
193
2068
0.90
0.57
32.1
26.7
g/l
328.7
330.0
0.83
182
2025
(40761535) Cells panel - Urine sediment
35
284
1.24
0.56
5.4
4.0
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
73
830
0.86
0.55
2.5
2.7
u/l
57.0
37.9
0.44
66
799
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
49
576
0.84
0.55
3.3
3.3
e6/l
1.9
1.4
0.46
31
357
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
8
122
0.65
0.55
4.3
3.2
—
2.7
—
0
13
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
53
453
1.18
0.52
5.8
5.7
kpa
4.9
5.1
0.73
46
417
(1761482) Bacteria [#/volume] in Urine by Culture
20
152
1.32
0.52
6.1
4.9
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
53
454
1.18
0.51
5.8
5.7
kpa
11.0
11.1
0.04
46
420
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
34
279
1.23
0.50
2.0
1.6
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
15
200
0.74
0.49
2.9
3.4
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
28
343
0.81
0.48
2.5
2.4
g/l
63.7
65.2
0.50
22
307
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
17
128
1.34
0.47
1.3
1.2
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
7
47
1.49
0.47
1.3
1.2
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
48
556
0.85
0.47
3.3
3.5
e6/l
1.5
2.0
0.43
30
340
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
8
116
0.68
0.46
1.6
1.5
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
71
629
1.14
0.46
6.7
5.2
kg/l
1.0
1.0
0.50
11
103
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
5
82
0.61
0.46
4.2
2.1
mg/l
1.9
2.2
—
5
69
(3037522) Nuclear Ab [Titer] in Serum
18
231
0.77
0.46
1.2
1.3
titre
228.6
330.4
—
7
54
(3035350) Ketones [Presence] in Urine by Test strip
130
1402
0.91
0.44
5.9
4.5
estimate
0.0
0.0
0.00
14
293
(3029937) Albumin [Presence] in Urine by Test strip
72
801
0.88
0.42
7.2
4.8
estimate
0.0
0.0
—
9
265
(3004588) Protein electrophoresis panel - Serum or Plasma
23
282
0.81
0.41
2.3
2.3
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
131
1408
0.91
0.41
6.0
4.7
estimate
0.0
0.0
0.00
12
280
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
5
33
1.52
0.41
1.4
1.6
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
(3011951) Aspergillus fumigatus IgE Ab [Units/volume] in Serum
0
15
0.00
0.41
0.0
1.1
—
0.1
—
0
10
(4306422)
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal
0
17
0.00
0.40
0.0
1.2
—
12.4
—
0
6
(40768441) Liver Pathology biopsy report
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
177
1875
0.92
0.40
6.1
4.7
mmol/l
7.7
7.0
1.80
164
1760
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
130
1395
0.91
0.40
8.0
6.3
estimate
0.0
0.0
0.00
14
285
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
90
983
0.90
0.39
2.3
2.3
mg/l
2.8
3.3
1.35
72
839
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
132
1414
0.91
0.39
2.6
2.2
pmol/l
85.0
89.1
0.51
85
773
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
32
374
0.85
0.37
5.3
4.3
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
5
37
1.35
0.37
1.2
1.2
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
5
37
1.35
0.37
1.6
2.0
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
26
217
1.20
0.35
5.4
4.5
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
74
671
1.11
0.35
39.8
32.6
inr
1.7
1.5
0.48
15
89
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
6
46
1.31
0.33
1.0
1.3
—
—
—
0
0
(3019225) pH of Specimen
25
293
0.85
0.31
4.8
3.8
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
7
55
1.27
0.30
2.0
1.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
67
728
0.91
0.28
2.1
2.6
—
—
—
0
0
(3022313) Gas panel - Capillary blood
15
183
0.81
0.28
4.6
4.0
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
134
1412
0.93
0.28
3.8
2.8
u/l
49.9
58.9
1.04
119
1271
(3020891) Body temperature
18
149
1.21
0.27
6.8
3.7
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
104
1106
0.93
0.27
7.1
5.1
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
14
113
1.24
0.26
4.9
4.2
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
81
0.74
0.24
1.0
1.0
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
71
659
1.09
0.23
2.6
3.2
mmol/l
2.5
2.5
0.58
55
557
(3019060) Gas panel - Arterial blood
32
285
1.13
0.22
3.9
3.4
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
7
95
0.73
0.22
4.4
2.7
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
5
42
1.19
0.21
1.2
1.3
—
—
—
0
0
(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
0
10
0.00
0.21
0.0
1.9
—
56.7
—
0
10
(3044007) Cell count panel - Peritoneal fluid
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
4.9
—
35.6
—
0
5
(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
2.8
—
120.9
—
0
10
(3003171) Aldosterone [Moles/volume] in Serum or Plasma --upright
0
11
0.00
0.21
0.0
1.1
—
289.6
—
0
5
(3014037) CD3+CD4+ (T4 helper) cells/100 cells in Blood
0
11
0.00
0.21
0.0
2.2
—
44.2
—
0
6
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
83
780
1.07
0.21
1.7
1.8
pmol/l
447.9
9076860.7
0.50
64
628
(3014576) Chloride [Moles/volume] in Serum or Plasma
49
450
1.09
0.21
7.3
6.5
mmol/l
105.8
104.1
1.65
49
435
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3043410) Blood group antigens tested for on Red Blood Cells
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3022192) Triglyceride [Mass/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
2.3
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
11
89
1.24
0.20
1.5
1.2
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
6
48
1.25
0.20
1.5
1.2
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
95
1000
0.94
0.20
2.2
2.8
—
—
—
0
0
(3051387) C reactive protein [Mass/volume] in Capillary blood
12
99
1.21
0.19
2.7
4.3
mg/l
13.9
34.6
—
7
68
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
6
51
1.18
0.19
2.2
1.6
mg/l
14.6
25.2
—
6
42
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
102
1069
0.94
0.19
2.0
2.1
nmol/l
70.2
79.2
2.97
79
918
(36660697) Celiac disease serology panel - Serum
11
131
0.84
0.17
1.0
1.2
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
13
110
1.18
0.17
1.7
1.4
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
13
110
1.18
0.17
1.7
1.4
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
5
67
0.74
0.17
1.8
2.6
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
5
70
0.71
0.16
3.0
2.2
g/l
3.3
3.6
—
5
65
(3024561) Albumin [Mass/volume] in Serum or Plasma
137
1417
0.96
0.16
4.6
4.4
g/l
34.3
33.5
0.84
125
1297
(3000991) Gas panel - Venous blood
34
313
1.09
0.15
7.1
7.2
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
7
88
0.79
0.14
3.1
3.6
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
90
937
0.95
0.14
2.4
2.3
u/l
47.0
56.0
3.19
84
865
(3011397) Hemoglobin [Presence] in Urine by Test strip
67
638
1.05
0.13
5.8
4.4
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
72
751
0.95
0.12
5.5
4.1
ng/l
117.6
281.0
1.12
64
675
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
67
640
1.05
0.11
2.2
1.8
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
5
44
1.14
0.10
1.2
1.3
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
5
44
1.14
0.10
1.2
1.2
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
43
451
0.95
0.09
1.9
1.7
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
141
1439
0.97
0.09
5.2
4.7
ng/l
52.0
58.8
0.22
113
1143
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
6
55
1.09
0.09
1.0
1.4
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
5
60
0.83
0.08
1.4
1.3
—
—
—
0
0
(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma
5
60
0.83
0.08
1.2
1.1
u/l
9.1
56.1
—
5
55
(3015171) Extractable nuclear Ab [Units/volume] in Serum
5
62
0.80
0.08
1.2
1.2
—
0.2
—
0
6
(3015377) Calcium [Moles/volume] in Serum or Plasma
107
1042
1.03
0.08
2.5
3.1
mmol/l
2.3
2.3
0.52
88
886
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
19
175
1.09
0.08
10.9
7.8
—
—
—
0
0
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
19
205
0.92
0.08
9.1
7.6
mmol/l
23.8
24.7
0.55
13
179
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
5
65
0.77
0.08
1.2
1.0
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
5
65
0.77
0.08
1.6
1.4
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
7
67
1.04
0.08
1.4
1.4
—
—
—
0
0
(4034850)
7
83
0.84
0.07
4.4
13.3
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
9
88
1.02
0.07
1.3
1.4
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
8
95
0.84
0.06
1.9
1.4
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
12
130
0.92
0.05
5.4
4.4
mmol/l
25.6
24.6
0.64
12
125
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
24
251
0.95
0.04
2.3
3.8
ng/l
113.2
104.0
0.14
16
218
(3012095) Magnesium [Moles/volume] in Serum or Plasma
53
516
1.03
0.04
2.3
2.8
mmol/l
0.8
0.8
0.11
46
472
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
44
450
0.97
0.03
1.9
1.7
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
24
232
1.03
0.02
2.6
3.3
ml/min/173m2
45.3
54.8
—
7
117
(3045414) Leukocytes [Presence] in Urine
11
103
1.07
0.01
1.6
2.2
—
—
—
0
0
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
18
173
1.04
0.01
2.1
1.7
ug/l
0.6
2.8
0.70
12
144
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
14
141
0.99
0.00
2.0
2.5
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
154
1540
1.00
0.00
14.3
13.6
inr
1.4
1.5
0.12
28
419
(3009445) Proteinase 3 Ab [Units/volume] in Serum
12
118
1.02
0.00
1.0
1.1
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
7
77
0.91
0.00
1.7
1.5
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
7
77
0.91
0.00
1.1
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
7
77
0.91
0.00
1.1
1.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
6
59
1.02
0.00
1.3
1.3
—
—
—
0
0
(21494814) CD8 cells/100 lymphocytes in Specimen
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
8
0.00
0.00
0.0
1.3
—
6.5
—
0
8
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
6
0.00
0.00
0.0
12.5
—
13.9
—
0
6
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.8
—
0.7
—
0
8
(3004716) Salmonella sp identified in Stool by Organism specific culture
8
89
0.90
0.00
1.1
1.3
—
—
—
0
0
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
1031.4
—
0
8
(3042631) Mycobacterium sp identified in Specimen
5
55
0.91
0.00
3.2
3.4
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3017962) TCRG gene rearrangements [Presence] in Blood or Tissue by Molecular genetics method
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
5.3
—
—
—
0
0
(3010726) Horse dander IgE Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3048879) Bone marrow aspiration report
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
49
1.02
0.00
1.2
1.3
—
—
—
0
0
(3030558) Cytomegalovirus DNA [Units/volume] (viral load) in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
7
76
0.92
0.00
1.1
1.2
—
—
—
0
0
(3005011) Chlamydia sp Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3020073) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Specimen
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3037534) Parathyrin related protein [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
122.6
—
0
5
(3012441) Differential panel - Pleural fluid
7
72
0.97
0.00
1.4
1.5
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3042602) Urea [Moles/volume] in Serum or Plasma --post dialysis
0
6
0.00
0.00
0.0
12.8
—
7.0
—
0
6
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
8
85
0.94
0.00
1.3
1.4
—
40.2
—
0
6
(3023430) Cat dander IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022689) Creatine [Moles/volume] in Urine
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3014444) EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(21491868) Cryoglobulin [Mass/volume] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
8.4
—
0
5
(44813793)
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3011335) Digoxin [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3013005) Retinol [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
2.0
—
0
6
(3005033) Fetal Nuchal fold Thickness US
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3018851) Theophylline [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.0
—
40.8
—
0
9
(3037692) Legionella sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(723474) SARS-CoV-2 (COVID-19) IgG Ab [Presence] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045788) Cell count panel - Pleural fluid
6
59
1.02
0.00
1.7
1.4
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
102.4
—
0
9
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3022907) Direct antiglobulin test.polyspecific reagent [Presence] on Red Blood Cells
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(4027681)
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint VD_MI and mortality.

Females

Parameter HR [95% CI] p-value
VD_MI 2.991 [2.64, 3.39] < 0.001
Birth year 1.0 [0.99, 1.01] 0.916

During the follow-up period (1.1.1998 — 31.12.2019), 3138 out of 3584 females with VD_MI died.

Males

Parameter HR [95% CI] p-value
VD_MI 3.558 [2.97, 4.26] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 2806 out of 3330 males with VD_MI died.

Mortality risk

Mortality risk for people of age

years, who have VD_MI.

N-year risk Females Males
1 0.241% 0.492%
5 1.79% 3.705%
10 4.924% 9.421%
15 9.633% 17.903%
20 16.907% 28.507%

Relationships between endpoints

Index endpoint: VD_MI – Vascular dementia (multiple infarctions)

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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