type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditions
|
461302 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
74734 |
6. Filter based on genotype QC (FinnGen only) |
71728 |
Control definitions (FinnGen only)
Control exclude
DIABETES_FG
Control conditions
not E4_DM1
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Type 2 diabetes, definitions combined
based on the number of shared cases.
Broader endpoints:
- Type 2 diabetes, definitions combined, including avohilmo
- Type 2 diabetes
- Diabetes, varying definitions
- Diabetes mellitus
- Endocrine, nutritional and metabolic diseases
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 71728 | 32050 | 39678 |
| Unadjusted period prevalence (%) | 16.65 | 12.59 | 19.93 |
| Median age at first event (years) | 60.52 | 59.75 | 61.14 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: T2D – Type 2 diabetes, definitions combined
GWS hits: 245
This endpoint is excluded (different definition than used in FinnGen).