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This is a non-core endpoint: only basic statistics are computed.

Toxic effect of other inorganic substances

ST19_TOXIC_EFFECT_OTHER_INORG_SUBST

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 T57
  • Cause of death: ICD-10 T57

2 out of 7 registries used, show all original rules.

23

4. Check minimum number of events

None

23

5. Include endpoints

None

23

6. Filter based on genotype QC (FinnGen only)

23

Control definitions (FinnGen only)

Control exclude
ST19_TOXIC_EFFEC_SUBST_CHIEF_NONME_SOURCE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
T5[1-9]|T6[0-5]
Name in latin
Effectus toxicus aliarum substantiarum non organicarum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 23 9 14
Unadjusted period prevalence (%) 0.00 0.00 0.01
Median age at first event (years) 46.48 42.25 49.20

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3007853) Bacteria identified in Skin by Aerobe culture
9
18
7.46
3.85
1.8
2.8
—
—
—
0
0
(3000991) Gas panel - Venous blood
7
19
4.81
2.37
3.3
8.1
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
6
14
5.38
2.32
3.5
5.4
mmol/l
25.2
25.6
—
6
14
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
13
67
3.16
1.86
3.7
2.5
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
7
26
3.41
1.75
1.1
1.5
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
9
42
2.86
1.57
1.9
1.9
—
—
—
0
0
(3015736) pH of Urine
13
72
2.85
1.57
4.2
3.3
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
11
57
2.78
1.48
3.1
2.4
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
8
34
3.06
1.48
1.4
1.7
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
10
50
2.77
1.43
9.0
4.6
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
9
49
2.37
1.17
6.3
6.2
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
23
199
+∞
1.05
16.7
13.7
mg/l
25.8
26.0
0.01
18
154
(3011397) Hemoglobin [Presence] in Urine by Test strip
8
44
2.25
0.99
4.1
2.9
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
11
67
2.23
0.97
2.6
1.8
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
7
38
2.20
0.83
2.0
1.9
mg/l
2.0
3.3
—
7
29
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
5
25
2.27
0.78
1.2
2.4
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
5
25
2.27
0.78
1.2
1.8
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
17
133
2.06
0.74
4.9
4.5
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
12
83
1.93
0.71
9.0
4.6
%
0.8
0.6
1.12
12
75
(3006504) Eosinophils/100 leukocytes in Blood
12
83
1.93
0.71
9.0
4.6
%
2.4
2.8
0.28
12
76
(3019069) Monocytes/100 leukocytes in Blood
12
83
1.93
0.71
9.1
4.9
%
9.9
8.9
0.62
12
77
(3044640) Blood type and Crossmatch panel - Blood
10
65
1.95
0.70
1.7
1.6
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
12
84
1.90
0.67
9.0
4.4
%
54.4
58.1
0.54
12
78
(40761511) CBC panel - Blood by Automated count
23
207
+∞
0.62
11.9
13.6
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
12
86
1.83
0.61
9.1
4.6
%
28.4
27.5
0.12
12
79
(3013707) Erythrocyte sedimentation rate by Westergren method
17
145
1.66
0.44
4.4
3.4
mm/h
10.1
13.3
0.61
17
129
(3017181) Myelocytes/100 leukocytes in Blood
0
15
0.00
0.43
0.0
3.8
—
0.6
—
0
5
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
7
50
1.57
0.37
1.7
1.5
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
8
65
1.35
0.32
2.5
2.4
nmol/l
92.0
72.0
—
8
56
(3021960) Folate [Moles/volume] in Serum or Plasma
5
41
1.28
0.24
1.6
1.4
nmol/l
22.0
22.4
—
5
31
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
12
101
1.39
0.23
2.8
3.2
—
—
—
0
0
(3008152) Bicarbonate [Moles/volume] in Arterial blood
0
11
0.00
0.22
0.0
7.1
—
22.0
—
0
11
(3022621) pH of Urine by Test strip
0
11
0.00
0.22
0.0
2.4
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
0
11
0.00
0.22
0.0
1.7
—
166.5
—
0
11
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.22
0.0
2.4
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
0
11
0.00
0.22
0.0
1.4
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
0
10
0.00
0.22
0.0
5.8
—
—
—
0
0
(3019225) pH of Specimen
0
10
0.00
0.22
0.0
3.3
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
0
10
0.00
0.22
0.0
2.3
—
4.6
—
0
10
(3019060) Gas panel - Arterial blood
0
12
0.00
0.22
0.0
5.5
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
7
56
1.36
0.21
5.6
3.0
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
0
14
0.00
0.21
0.0
3.9
—
0.2
—
0
5
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
7
87
0.72
0.19
5.4
4.3
ug/l
2.8
2.1
—
7
78
(3044889) 12 lead EKG panel
12
135
0.77
0.15
2.4
3.4
—
—
—
0
0
(40758558) Short blood count panel - Blood
5
44
1.17
0.11
7.4
7.2
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
16
148
1.27
0.09
8.3
7.3
u/l
69.3
77.7
0.60
16
137
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
13
128
1.04
0.00
3.8
3.5
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
7
75
0.90
0.00
2.4
2.3
ug/l
48.3
134.8
—
7
62
(3038515) Glucose [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
4.3
—
6.8
—
0
6
(40768793) Breast Pathology biopsy report
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.0
—
553.0
—
0
8
(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
3.8
—
3.9
—
0
5
(1616796) Gas panel - Central venous blood
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
5
57
0.84
0.00
5.8
3.0
ug/l
0.6
0.8
—
5
38
(3003338) MCHC [Mass/volume]
18
174
1.16
0.00
28.2
16.9
g/l
334.3
334.1
0.03
18
174
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
3.8
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3035941) MCH [Entitic mass]
23
224
+∞
0.00
25.7
18.7
pg
30.4
30.4
0.05
23
219
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3024731) MCV [Entitic volume]
23
224
+∞
0.00
25.6
18.7
fl
90.9
90.6
0.07
23
219
(3014051) Protein [Presence] in Urine by Test strip
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
7
0.00
0.00
0.0
7.1
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3020044) Glucose [Moles/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
4.4
—
0
7
(3035285) Chloride [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
3.8
—
107.6
—
0
5
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
0
8
0.00
0.00
0.0
2.3
—
2.1
—
0
8
(4034850)
0
6
0.00
0.00
0.0
5.2
—
—
—
0
0
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.3
—
0.5
—
0
9
(3007930) Methemoglobin/Hemoglobin.total in Blood
0
9
0.00
0.00
0.0
6.8
—
0.6
—
0
9
(3022313) Gas panel - Capillary blood
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3007461) Platelets [#/volume] in Blood
23
223
+∞
0.00
25.8
18.8
e9/l
245.4
248.3
0.10
23
216
(3008037) Lactate [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
4.3
—
1.1
—
0
6
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3000963) Hemoglobin [Mass/volume] in Blood
23
224
+∞
0.00
26.2
18.8
g/l
136.0
138.4
0.40
23
219
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
7
70
1.00
0.00
4.6
4.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_TOXIC_EFFECT_OTHER_INORG_SUBST – Toxic effect of other inorganic substances

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).