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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Injury of heart

ST19_INJURY_HEART

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 S26
  • Cause of death: ICD-10 S26

2 out of 7 registries used, show all original rules.

73

4. Check minimum number of events

None

73

5. Include endpoints

None

73

6. Filter based on genotype QC (FinnGen only)

73

Control definitions (FinnGen only)

Control exclude
ST19_INJURI_THORAX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S2
Name in latin
Laesio cordis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 73 26 47
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 56.78 64.72 52.40

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
65
Matched controls
649
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S26.0
ICD-10 Finland
Injury of heart with haemopericardium
+∞
38.4
33
*
S26.8
ICD-10 Finland
Other injuries of heart
+∞
29.4
26
*
S22.2
ICD-10 Finland
Fracture of sternum
+∞
10.7
10
*
S26.9
ICD-10 Finland
Injury of heart, unspecified
+∞
9.6
9
*
S27.3
ICD-10 Finland
Other injuries of lung
+∞
9.6
9
*
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
17.6
8.6
13
9
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.9
7.7
23
55
S22.4
ICD-10 Finland
Multiple fractures of ribs
+∞
7.4
7
*
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
77.1
6.6
7
*
S36.1
ICD-10 Finland
Injury of liver or gallbladder
+∞
6.3
6
*
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
+∞
6.3
6
*

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_INJURY_HEART – Injury of heart

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).