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Certolizumab pegol

Endpoint Browser

RX_L04AB05

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC — L04AB05

1 out of 7 registries used, show all original rules.

633

4. Check minimum number of events

Min. number of events 3
633

5. Include endpoints

None

633

6. Filter based on genotype QC (FinnGen only)

633

Control definitions (FinnGen only)

Control exclude
RX_L04AB

Extra metadata

First used in FinnGen datafreeze
DF4

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 633 505 128
Unadjusted period prevalence (%) 0.15 0.17 0.06
Median age at first event (years) 41.75 39.72 49.80

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
511
Matched controls
5107
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1791.2
323.0
505
223
A07EC01
ATC
sulfasalazine; oral, rectal
168.4
323.0
424
143
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
160.5
323.0
445
205
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
13120.6
323.0
504
21
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
9362.1
323.0
505
19
L04AB05
ATC
certolizumab pegol; parenteral
+∞
323.0
511
*
L04AB01
ATC
etanercept; parenteral
4865.4
313.0
269
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
82.9
311.2
349
129
L04AB04
ATC
adalimumab; parenteral
4590.3
302.3
261
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
157.3
296.1
295
44
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
66.5
293.1
346
156
P01BA02
ATC
hydroxychloroquine; oral
45.3
241.7
310
168
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
69.3
227.1
258
74
L04AA13
ATC
leflunomide; oral
126.5
194.3
201
26
L04AB06
ATC
golimumab; parenteral
+∞
181.3
163
*
L88
ICPC
Rheumatoid/seropositive arthritis
62.5
163.0
188
47
H02AB06
ATC
prednisolone; systemic
19.9
156.6
458
1549
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
9.5
114.7
315
738
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
61.9
106.4
123
26
L04AA24
ATC
abatacept; parenteral
592.5
101.3
97
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
48.0
93.2
113
30
M45
ICD-10 Finland
Ankylosing spondylitis
44.1
92.3
114
33
M13.9
ICD-10 Finland
Arthritis, unspecified
13.9
83.5
153
152
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
61.9
83.0
96
19
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
10.7
79.1
168
223
L04AC10
ATC
secukinumab; parenteral
283.1
73.4
73
*
M01CB01
ATC
sodium aurothiomalate; parenteral
91.4
71.4
78
10
L04AC07
ATC
tocilizumab; parenteral
+∞
70.5
66
*
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
38.2
63.8
81
25
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
88.1
62.8
69
9
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
29.8
61.4
83
33
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
8.6
59.9
143
221
TNG10
NOMESCO Finland
Puncture of knee
61.1
59.6
69
13
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.8
59.2
293
1121
L04AA11
ATC
[U] etanercept; parenteral
624.7
57.8
56
*
L04AA01
ATC
[U] ciclosporin; systemic
39.7
57.2
72
21
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
115.2
57.2
61
6
WZA10
NOMESCO Finland
Long statement of health and health related matters
36.6
54.7
70
22
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
+∞
54.1
51
*
L40.5
ICD-10 Finland
Arthropathic psoriasis
36.0
53.7
69
22
L04AA17
ATC
[U] adalimumab; parenteral
+∞
50.9
48
*
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
98.4
48.9
53
6
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
47.5
48.8
59
14
H02AB07
ATC
prednisone; oral
6.2
48.0
147
314
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
+∞
47.6
45
*
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
176.1
46.7
48
*
291
Kela drug reimbursment
Tofacitinib
489.3
46.0
45
*
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
30.7
45.0
60
22
L04AA29
ATC
tofacitinib; oral
477.3
45.0
44
*
L04AD01
ATC
ciclosporin; systemic
20.3
43.7
66
37
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
126.1
43.5
46
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
26.0
43.0
60
26
M07.3
ICD-10 Finland
Other psoriatic arthropathies
55.2
42.5
50
10
R4120
NOMESCO Finland
Occupational therapy
8.1
41.0
98
145
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
8.7
40.6
92
125
M01AH05
ATC
etoricoxib; oral
3.7
39.9
381
2251
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
11.8
37.4
71
69
M01AH01
ATC
celecoxib; oral (coxibs)
4.5
37.4
154
444
ZX120
NOMESCO Finland
Intravenous
6.4
36.4
104
197
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
17.7
36.1
57
36
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
20.2
35.3
53
29
NDG30
NOMESCO Finland
Fusion of wrist, total
193.2
35.2
36
*
L04AX01
ATC
azathioprine; systemic
8.7
35.1
79
105
XX9XE
NOMESCO Finland
Other ultrasound examination
45.6
34.6
42
10
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
30.7
33.9
45
16
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
13.5
33.4
59
49
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
66.3
32.5
37
6
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
7.2
32.5
83
134
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
14.5
32.3
55
42
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
26.6
32.0
44
18
NF1AA
NOMESCO Finland
Hip X-ray examination
7.5
31.7
78
119
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
23.4
31.5
45
21
NH3EA
NOMESCO Finland
Feet X-ray examination with load
14.6
31.2
53
40
3005
Kela drug reimbursment
Tofacitinib
332.2
31.2
31
*
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
170.3
31.0
32
*
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
49.6
31.0
37
8
Z3226
NOMESCO Finland
Physiotherapist
3.8
30.8
155
525
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
5.1
29.9
103
241
M01AC06
ATC
meloxicam; systemic, rectal
3.1
29.9
235
1108
R4110
NOMESCO Finland
Physiotherapy
3.3
29.8
193
793
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
9.9
29.6
61
69
N02AX02
ATC
tramadol; systemic, rectal
2.9
27.2
246
1247
M01CB03
ATC
auranofin; oral
63.5
26.3
30
5
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
63.5
26.3
30
5
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
33.0
26.3
34
11
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.7
25.9
285
1612
TND10
NOMESCO Finland
Joint puncture, wrist or finger joint
98.6
25.9
28
*
A02BC02
ATC
pantoprazole; systemic
2.8
25.8
357
2316
ZX140
NOMESCO Finland
Intra articular
30.2
25.7
34
12
M01AE02
ATC
naproxen; oral, rectal
2.8
25.3
360
2358
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
5.8
25.3
75
146
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
24.9
25.1
35
15
TNH10
NOMESCO Finland
Joint puncture, ankle joint or foot joint
136.7
24.8
26
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
8.1
24.7
57
78
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
24.3
230
1176
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
27.0
24.3
33
13
L04AA37
ATC
baricitinib; oral
251.2
23.8
24
*
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
23.4
23.3
33
15
H20.1
ICD-10 Finland
Chronic iridocyclitis
20.1
22.9
34
18
3006
Kela drug reimbursment
Baricitinib
240.3
22.8
23
*
M06
ICD-10 Finland
Other rheumatoid arthritis
125.6
22.8
24
*
NG1DA
NOMESCO Finland
X-ray of knees
14.1
22.3
38
29
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
13.2
21.2
37
30
H02AB04
ATC
methylprednisolone; systemic
3.5
21.2
109
364
L01CB
ATC
Podophyllotoxin derivatives
+∞
21.0
20
*
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
7.9
20.8
48
66
293
Kela drug reimbursment
Baricitinib
218.5
20.7
21
*
L04AC13
ATC
ixekizumab; parenteral
218.5
20.7
21
*
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
21.2
20.6
30
15
RT272
NOMESCO Finland
NA
60.0
20.1
23
*
ZXX03
NOMESCO Finland
Extent of procedure, 3 units
37.4
20.0
25
7
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
22.7
19.7
28
13
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
8.9
19.6
42
51
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
8.2
19.5
44
58
WX320
NOMESCO Finland
Spinalanesthesy
2.8
19.2
146
637
TNC11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in elbow joint
72.7
18.8
21
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
18.5
274
1699
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
7.4
18.4
44
64
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.8
18.3
63
145
Z3229
NOMESCO Finland
Other healthcare associate professional
4.6
18.2
66
160
ZXA00
NOMESCO Finland
Right side
2.7
18.0
146
654
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
21.0
17.9
26
13
L04AC14
ATC
sarilumab; systemic
+∞
17.8
17
*
3029
Kela drug reimbursment
Upadacitinib
+∞
17.8
17
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.1
17.7
72
195
D05AX52
ATC
calcipotriol, combinations; topical
5.7
17.7
52
100
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.4
17.6
214
1194
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
186.2
17.6
18
*
NB2AT
NOMESCO Finland
Intra artrial injection of shoulder with ultrasound guidance
19.5
17.5
26
14
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
5.8
17.4
50
93
L04AC05
ATC
ustekinumab; parenteral
43.6
17.4
21
5
NHG22
NOMESCO Finland
Fusion of subtalar joint
32.7
17.2
22
7
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
16.9
128
551
N02AJ06
ATC
codeine and paracetamol; systemic
2.3
16.5
226
1326
M25.5
ICD-10 Finland
Pain in joint
2.4
16.4
187
1001
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.2
16.3
65
173
NDL52
NOMESCO Finland
Tenosynovectomy of hand
31.2
16.2
21
7
E0000UV
ATC
NA
2.2
16.2
242
1473
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.4
16.1
83
275
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
10.2
15.9
31
32
J01FF01
ATC
clindamycin; systemic
2.4
15.7
163
831
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.7
15.4
53
122
M05BA04
ATC
alendronic acid; oral
5.8
15.4
44
82
WX203
NOMESCO Finland
Infraclavicular plexus blockade
7.6
15.0
35
49
WZC30
NOMESCO Finland
Teaching
3.1
14.9
91
337
M13.8
ICD-10 Finland
Other specified arthritis
21.8
14.8
21
10
M05BA06
ATC
ibandronic acid; systemic
14.7
14.7
24
17
7143D
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[OLIGARTHRITIS JUVENILIS]
+∞
14.6
14
*
298
Kela drug reimbursment
NA
+∞
14.6
14
*
RT271
NOMESCO Finland
NA
82.5
14.6
16
*
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
28.1
14.4
19
7
N02BE01
ATC
paracetamol; systemic, rectal
2.7
14.3
447
3700
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.7
14.3
64
188
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
6.7
14.2
36
57
SPAT1325
SPAT
Vaccination
2.2
14.1
173
949
H02AB08
ATC
triamcinolone; systemic
54.9
13.9
16
*
NDG76
NOMESCO Finland
Fusion of DIP joint
20.7
13.9
20
10
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.9
13.8
45
98
A04AA01
ATC
ondansetron; systemic, rectal
4.3
13.7
52
132
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
11.4
13.6
25
23
ZXA10
NOMESCO Finland
Bilateral
2.7
13.6
104
443
7143C
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[POLYARTHRITIS JUVENILIS SERONEGATIVA]
+∞
13.6
13
*
SPAT1202
SPAT
Intra-articular injection
7.9
13.4
30
40
ZXA05
NOMESCO Finland
Left side
2.4
13.1
127
615
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
29.2
13.0
17
6
D07AD01
ATC
clobetasol; topical
2.7
12.8
97
411
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.7
12.8
97
412
J01DB01
ATC
cefalexin; oral
2.5
12.6
442
3692
A02BC05
ATC
esomeprazole; systemic
2.1
12.6
208
1281
Z3231
NOMESCO Finland
Registered nurse
2.2
12.6
153
827
L04AA44
ATC
upadacitinib; oral
+∞
12.5
12
*
RT310
NOMESCO Finland
NA
+∞
12.5
12
*
9256
FHL
Synovectomy (knee 9311)
+∞
12.5
12
*
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
4.6
12.5
43
99
D07AC13
ATC
mometasone; topical
2.2
12.5
161
893
NF1DA
NOMESCO Finland
X-ray of hips
12.0
12.4
22
19
D07XC01
ATC
betamethasone, combinations; topical
3.1
12.4
73
262
D07AC01
ATC
betamethasone; topical
2.1
12.1
183
1085
L20
ICPC
Joint symptom/complaint NOS
5.4
12.1
36
71
RK220
NOMESCO Finland
NA
47.8
11.9
14
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.5
11.9
56
172
M01AH02
ATC
rofecoxib; oral
2.9
11.9
75
283
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
11.8
191
1159
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
4.6
11.8
41
96
A02BC03
ATC
lansoprazole; oral
2.2
11.8
151
830
H04.10
ICD-10 Finland
Dry eye syndrome
3.0
11.7
71
263
NDF10
NOMESCO Finland
Synovectomy of wrist
+∞
11.5
11
*
M05.3
ICD-10 Finland
Rheumatoid arthritis with involvement of other organs and systems
+∞
11.5
11
*
M08.9
ICD-10 Finland
Juvenile arthritis, unspecified
122.6
11.5
12
*
ND1AA
NOMESCO Finland
Wrist X-ray examination
3.8
11.5
49
139
Z2221
NOMESCO Finland
Medical doctor
2.1
11.5
172
1010
M13.0
ICD-10 Finland
Polyarthritis, unspecified
12.2
11.4
20
17
N03AX16
ATC
pregabalin; oral
2.2
11.4
127
655
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
9.2
11.4
23
26
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.4
11.3
106
503
J02AC01
ATC
fluconazole; systemic
1.9
11.3
251
1709
RT171
NOMESCO Finland
NA
35.9
11.3
14
*
H02BX01
ATC
methylprednisolone, combinations; systemic
5.2
11.2
34
69
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.0
11.1
68
252
TQW40
NOMESCO Finland
Remowal of suture of skin
3.5
11.1
53
165
WX002
NOMESCO Finland
Sedation and analgesia
2.4
11.0
102
482
NHG20
NOMESCO Finland
Fusion of talocrural joint
44.3
11.0
13
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
10.8
90
399
NH1AD
NOMESCO Finland
Ankle and foot CT
7.8
10.8
24
32
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
3.7
10.8
47
136
4AA12
NOMESCO Finland
NA
22.0
10.7
15
7
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
13.3
10.7
18
14
9503
FHL
Tendon or tendon sheath cleansing surgery (tenosynovectomy)
61.3
10.7
12
*
M19.2
ICD-10 Finland
Other secondary arthrosis
10.4
10.6
20
20
K07.60
ICD-10 Finland
Snapping jaw
3.2
10.6
55
183
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
4.6
10.5
36
83
D05AX02
ATC
calcipotriol; topical
4.8
10.5
34
74
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.0
10.5
41
108
NDB60
NOMESCO Finland
Prosthetic replacement of MCP joint of finger
112.2
10.5
11
*
TNB10
NOMESCO Finland
Joint puncture, shoulder joint
112.2
10.5
11
*
M07.2*L40.5
ICD-10 Finland
Psoriatic spondylitis
112.2
10.5
11
*
D06BB04
ATC
podophyllotoxin; topical
3.0
10.4
60
214
M02AA07
ATC
piroxicam; topical
2.0
10.4
169
1016
M01AE52
ATC
naproxen and esomeprazole; oral
4.9
10.3
33
71
ZXX04
NOMESCO Finland
Extent of procedure, 4 units
23.9
10.3
14
6
M01AB01
ATC
indometacin; systemic, rectal
4.8
10.2
33
72
M05BA07
ATC
risedronic acid; oral
7.5
10.1
23
32
M01AB55
ATC
diclofenac, combinations; oral
4.0
10.1
40
107
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
15.0
10.1
16
11
7140B
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SERONEGATIVA]
40.9
10.0
12
*
J01MA12
ATC
levofloxacin; systemic
2.4
9.9
90
416
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
9.9
198
1284
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
7.6
9.8
22
30
A03FA01
ATC
metoclopramide; systemic, rectal
2.2
9.8
115
605
M06.4
ICD-10 Finland
Inflammatory polyarthropathy
56.1
9.7
11
*
NG1EA
NOMESCO Finland
Knee X-ray examination with wrench
11.7
9.6
17
15
B01AB05
ATC
enoxaparin; parenteral
2.0
9.6
143
829
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
6.8
9.5
23
35
ZXE00
NOMESCO Finland
One hour or less
1.8
9.5
219
1482
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
101.8
9.4
10
*
RK210
NOMESCO Finland
NA
101.8
9.4
10
*
TEG00
NOMESCO Finland
Punction of mandibular joint
101.8
9.4
10
*
NDF60
NOMESCO Finland
Operation for osteochondritis of a joint of hand,v
30.6
9.4
12
*
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
30.6
9.4
12
*
J05AB11
ATC
valaciclovir; oral
2.4
9.4
87
407
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
9.4
204
1352
M05.0
ICD-10 Finland
Felty syndrome
+∞
9.4
9
*
TNF11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in hip joint
+∞
9.4
9
*
M17.5
ICD-10 Finland
Other secondary gonarthrosis
10.9
9.3
17
16
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.5
9.3
43
131
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
7.5
9.3
21
29
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
9.1
112
597
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.4
9.0
32
77
M46.8
ICD-10 Finland
Other specified inflammatory spondylopathies
37.4
9.0
11
*
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
19.0
9.0
13
7
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
19.0
9.0
13
7
EG1CG
NOMESCO Finland
Extensive MRI examination of mandipular joint with high intensity magnet
24.5
8.9
12
5
1XC02
NOMESCO Finland
NA
24.5
8.9
12
5
S18
ICPC
Laceration/cut
1.8
8.9
191
1256
M66.0
ICD-10 Finland
Rupture of popliteal cyst
12.8
8.9
15
12
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
8.9
225
1560
M01AX17
ATC
nimesulide; oral
2.1
8.8
106
560
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.0
8.8
50
177
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
14.3
8.7
14
10
R4180
NOMESCO Finland
Podiatric therapy
14.3
8.7
14
10
M03BX02
ATC
tizanidine; oral
1.8
8.7
323
2520
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.9
8.7
35
95
E000001
ATC
NA
2.0
8.7
127
727
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
50.9
8.7
10
*
ND1AE
NOMESCO Finland
Wrist ultrasound examination
50.9
8.7
10
*
ZX112
NOMESCO Finland
Subcutaneous
6.0
8.7
23
40
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.1
8.5
112
615
4AB02
NOMESCO Finland
NA
20.4
8.5
12
6
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
3.6
8.5
37
108
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
4.5
8.5
29
68
NCF10
NOMESCO Finland
Synovectomy of elbow joint, open
+∞
8.4
8
*
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
7.3
8.3
19
27
M01AB05
ATC
diclofenac; systemic, rectal
1.7
8.3
332
2633
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
8.2
128
747
M25.4
ICD-10 Finland
Effusion of joint
8.3
8.1
17
21
M16.7
ICD-10 Finland
Other secondary coxarthrosis
12.0
8.1
14
12
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
6.5
8.1
20
32
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
6.8
8.0
19
29
ZXE20
NOMESCO Finland
More than three and less than five hours
2.4
7.9
66
294
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.1
7.9
29
73
R2110
NOMESCO Finland
Giving the first information
2.6
7.9
56
227
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.1
7.8
29
74
J01AA02
ATC
doxycycline; systemic
1.8
7.8
371
3068
M02AA10
ATC
ketoprofen; topical
2.3
7.8
75
360
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
15.3
7.7
12
8
TNF10
NOMESCO Finland
Puncture of hip joint
45.7
7.7
9
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
7.7
59
252
S01FA02
ATC
scopolamine; ophthalmic
18.7
7.6
11
6
ZZH31
NOMESCO Finland
Bone allograft, small pieces
18.7
7.6
11
6
M81.9
ICD-10 Finland
Osteoporosis, unspecified
5.6
7.6
21
39
WX204
NOMESCO Finland
Axillary plexus blockaced
4.8
7.6
24
52
NH3AE
NOMESCO Finland
Feet ultrasound examination
25.4
7.6
10
*
TNH33
NOMESCO Finland
Custom moulded brace, ankle or foot
7.3
7.5
17
24
M05BX04
ATC
denosumab; parenteral
4.4
7.5
26
62
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.5
7.5
33
98
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
5.7
7.4
20
36
NF1AT
NOMESCO Finland
Puncture of hip joint with ultrasound guidance
81.2
7.4
8
*
9522
FHL
Synovectomy
81.2
7.4
8
*
RT274
NOMESCO Finland
NA
81.2
7.4
8
*
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
13.6
7.4
12
9
E000002
ATC
NA
2.2
7.4
74
360
M08.8
ICD-10 Finland
Other juvenile arthritis
+∞
7.3
7
*
M46.0
ICD-10 Finland
Spinal enthesopathy
+∞
7.3
7
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
6.4
7.3
18
29
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
3.4
7.2
33
101
ZXX06
NOMESCO Finland
Extent of procedure, 6 units
30.5
7.2
9
*
ZXX05
NOMESCO Finland
Extent of procedure, 5 units
30.5
7.2
9
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.4
7.1
58
254
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.7
7.1
29
81
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
7.1
165
1098
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
7.1
276
2126
R5120
NOMESCO Finland
Preparation of an aid
7.1
7.0
16
23
N03AX12
ATC
gabapentin; oral
2.1
7.0
78
397
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.2
7.0
70
342
L17
ICPC
Foot/toe symptom/complaint
1.9
7.0
117
698
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
7.7
6.9
15
20
L40.8
ICD-10 Finland
Other psoriasis
14.0
6.9
11
8
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
4.9
6.9
21
44
B01AB04
ATC
dalteparin; parenteral
3.6
6.9
29
83
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.7
6.9
174
1182
M01AB08
ATC
etodolac; oral
2.9
6.9
41
151
R50.9
ICD-10 Finland
Fever, unspecified
2.1
6.9
77
393
RS221
NOMESCO Finland
NA
6.8
6.9
16
24
Z2446
NOMESCO Finland
Social worker
2.8
6.8
43
164
TEG10
NOMESCO Finland
Injection of diagnostic or therapeutic substance into mandibular joint
17.0
6.8
10
6
H25.1
ICD-10 Finland
Senile nuclear cataract
2.4
6.8
56
249
TGC00
NOMESCO Finland
Bronchial lavation
6.6
6.7
16
25
A28
ICPC
Limited function/disability NOS
2.7
6.7
44
173
NHG82
NOMESCO Finland
Fusion of other tarsal joint
12.5
6.6
11
9
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.9
6.6
25
66
J01MA02
ATC
ciprofloxacin; systemic
1.7
6.6
163
1100
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.2
6.6
65
316
P01BA01
ATC
chloroquine; systemic
70.7
6.4
7
*
319
Kela drug reimbursment
Adalimumab, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, sekukinumab and ustekinumab (skin psoriasis)
14.5
6.4
10
7
VALMI
NOMESCO Finland
NA
1.7
6.4
141
919
N02AA05
ATC
oxycodone; systemic
2.4
6.4
51
223
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
8.3
6.4
13
16
N06AX21
ATC
duloxetine; oral
2.2
6.3
63
308
4AC07
NOMESCO Finland
NA
+∞
6.3
6
*
RJ210
NOMESCO Finland
NA
+∞
6.3
6
*
H221, M084
ICD-10 Finland
NA
+∞
6.3
6
*
9269
FHL
Other measure in this category
+∞
6.3
6
*
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
6.3
6
*
QDH05
NOMESCO Finland
Correction of deformity of toe nail
27.0
6.2
8
*
NDG77
NOMESCO Finland
Other excision, reconstruction or fusion of joint of first finger
27.0
6.2
8
*
J05AB01
ATC
aciclovir; systemic
1.8
6.2
113
692
N02AJ13
ATC
tramadol and paracetamol; systemic
5.1
6.2
18
36
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.1
6.2
18
36
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.3
6.2
57
264
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
5.5
6.2
17
32
Z50.1
ICD-10 Finland
Other physical therapy
3.1
6.1
32
109
-1
NOMESCO Finland
NA
1.6
6.1
190
1362
EB1WA
NOMESCO Finland
NA
12.7
6.1
10
8
M01AX01
ATC
nabumetone; oral
3.6
6.1
25
71
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
6.8
6.1
14
21
Z71.8
ICD-10 Finland
Other specified counselling
1.7
6.1
138
905
A02BC01
ATC
omeprazole; systemic
1.7
6.0
128
824
M79.7
ICD-10 Finland
Fibromyalgia
3.3
6.0
28
88
R5140
NOMESCO Finland
Monitoring the use of the aid
2.5
6.0
46
197

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: RX_L04AB05 – Certolizumab pegol

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).