lung disease: A disease involving the lung.
Respiratory disorders in diseases classified elsewhere
DOID EFO Endpoint Browser PheWeb
RESP_ILL_DIS_CLASS_ELSEWHERE
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
474 |
4. Check minimum number of eventsNone |
474 |
5. Include endpointsNone |
474 |
6. Filter based on genotype QC (FinnGen only) |
474 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Respiratory disorders in diseases classified elsewhere
based on the number of shared cases.
Similar with more cases:
- Other diseases of pleura
- Other pulmonary diagnosis
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
- ILD differential diagnosis
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2217 | 1242 | 966 |
| Only index persons | 1831 | 1044 | 787 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.04 | 0.03 |
| Only index persons | 0.03 | 0.04 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 65.05 | 65.35 | 64.68 |
| Only index persons | 64.02 | 64.19 | 63.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 474 | 281 | 193 |
| Unadjusted period prevalence (%) | 0.09 | 0.10 | 0.09 |
| Median age at first event (years) | 61.90 | 60.20 | 64.36 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 416
- Matched controls
- 4159
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
49.5
235.0
316
249
L04AX01
ATC
azathioprine; systemic
50.6
169.4
206
79
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
154.0
138
*
M31.3
ICD-10 Finland
Wegener granulomatosis
894.1
135.8
126
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
33.7
128.3
172
85
P01BA02
ATC
hydroxychloroquine; oral
19.2
112.5
186
168
H02AB06
ATC
prednisolone; systemic
15.2
107.6
369
1419
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
105.9
97
*
L04AA06
ATC
mycophenolic acid; systemic
56.3
100.5
118
29
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
9.5
94.5
310
979
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
14.7
90.5
166
179
J99.0*M05.1
ICD-10 Finland
Rheumatoid lung disease
+∞
78.7
73
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
15.2
78.4
139
133
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
30.5
78.3
106
46
UGC12
NOMESCO Finland
Flexible bronchoscopy
13.6
78.1
147
161
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
15.1
77.8
138
132
TGC00
NOMESCO Finland
Bronchial lavation
30.2
73.8
100
43
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.2
70.9
322
1347
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
49.1
66.5
80
20
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
10.2
66.4
146
209
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
14.8
65.6
116
106
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
34.0
59.7
78
28
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
57.7
54
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
34.3
56.8
74
26
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
12.1
55.2
107
116
M05BA04
ATC
alendronic acid; oral
9.0
54.9
128
195
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.3
50.4
202
628
J99.1*M35.0
ICD-10 Finland
Respiratory disorders in sicca syndrome [Sjögren]
+∞
48.9
46
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
15.0
47.7
82
67
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
9.7
46.5
101
133
XG410
NOMESCO Finland
Flow-volume spirometry
14.7
45.7
79
65
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
57.9
43.8
51
10
J99.0
ICD-10 Finland
Rheumatoid lung disease
+∞
42.4
40
*
M33.2
ICD-10 Finland
Polymyositis
+∞
39.2
37
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
35.3
38.9
50
16
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
10.6
37.5
76
86
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
36.0
34
*
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
+∞
36.0
34
*
A07EC01
ATC
sulfasalazine; oral, rectal
6.7
32.7
90
165
GD1AD
NOMESCO Finland
Thorax CT examination
9.2
31.4
68
86
H02AB07
ATC
prednisone; oral
4.7
31.2
121
331
J99.1*M32.1
ICD-10 Finland
Respiratory disorders in systemic: lupus erythematosus
+∞
30.6
29
*
J99.1*M34.8
ICD-10 Finland
Respiratory disorders in systemic: sclerosis
+∞
29.5
28
*
ZX120
NOMESCO Finland
Intravenous
5.4
29.2
97
223
1XC02
NOMESCO Finland
NA
47.6
29.2
35
8
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
10.5
29.0
58
63
DHA10
NOMESCO Finland
Biopsy of cavity of nose
39.2
28.9
36
10
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.9
28.5
75
128
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
+∞
27.4
26
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.5
26.0
148
560
R50.9
ICD-10 Finland
Fever, unspecified
4.1
25.7
115
354
L04AA13
ATC
leflunomide; oral
11.7
25.6
48
46
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
10.8
25.6
50
52
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.3
24.8
82
185
L01AA01
ATC
cyclophosphamide; systemic
51.7
24.6
29
6
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
19.6
24.0
36
20
J01MA12
ATC
levofloxacin; systemic
3.4
23.2
134
504
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
11.6
23.0
43
41
J01MA14
ATC
moxifloxacin; systemic
4.8
22.8
82
202
L88
ICPC
Rheumatoid/seropositive arthritis
7.9
22.7
53
75
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.9
22.6
67
132
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.1
22.5
64
120
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.7
22.2
81
202
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
28.2
21.6
29
11
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
21.4
134
531
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.0
21.3
73
170
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
115.9
20.8
22
*
C03CA01
ATC
furosemide; systemic
2.9
20.5
162
746
R06.0
ICD-10 Finland
Dyspnoea
2.9
20.0
157
718
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
9.2
20.0
42
50
J99.1*M33.9
ICD-10 Finland
Respiratory disorders in dermatopolymyositis
+∞
20.0
19
*
A02BC02
ATC
pantoprazole; systemic
2.8
19.5
312
2158
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.6
19.2
95
312
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
19.0
218
1240
M33.1
ICD-10 Finland
Other dermatomyositis
73.4
18.9
21
*
L04AD01
ATC
ciclosporin; systemic
10.8
18.8
36
36
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
55.1
18.1
21
*
M05.1
ICD-10 Finland
Rheumatoid lung disease
+∞
17.8
17
*
M35.1
ICD-10 Finland
Other overlap syndromes
44.0
17.4
21
5
L04AA01
ATC
[U] ciclosporin; systemic
13.0
16.1
28
23
M13.9
ICD-10 Finland
Arthritis, unspecified
4.5
15.8
58
144
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
166.0
15.6
16
*
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
39.7
15.5
19
5
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.1
15.5
64
178
H04.10
ICD-10 Finland
Dry eye syndrome
3.8
15.4
69
206
ZX108
NOMESCO Finland
Inhalation
21.0
15.3
22
11
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
11.5
15.2
28
26
NH3EA
NOMESCO Finland
Feet X-ray examination with load
10.7
15.2
29
29
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.8
14.8
67
202
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
83.1
14.7
16
*
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
155.2
14.6
15
*
M34.0
ICD-10 Finland
Progressive systemic sclerosis
155.2
14.6
15
*
J96.1
ICD-10 Finland
Chronic respiratory failure
9.6
13.9
28
31
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
55.3
13.9
16
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
9.0
13.5
28
33
H02AB04
ATC
methylprednisolone; systemic
2.8
13.5
96
399
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
8.0
13.4
30
40
WZA10
NOMESCO Finland
Long statement of health and health related matters
12.7
13.3
23
19
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
6.5
13.2
34
56
M05BB03
ATC
alendronic acid and colecalciferol; oral
8.5
13.0
28
35
J01FF01
ATC
clindamycin; systemic
2.4
13.0
134
682
M05BA07
ATC
risedronic acid; oral
6.4
13.0
34
57
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
12.8
93
391
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
12.8
12.8
22
18
1AA01
NOMESCO Finland
NA
72.1
12.7
14
*
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
133.9
12.5
13
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
6.6
12.2
31
50
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
6.8
12.1
30
47
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
12.0
230
1541
C08CA05
ATC
nifedipine; systemic
4.0
12.0
49
135
J31.0
ICD-10 Finland
Chronic rhinitis
3.7
11.8
52
153
M60.9
ICD-10 Finland
Myositis, unspecified
31.0
11.7
15
5
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
11.6
149
839
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
14.2
11.6
19
14
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
11.5
193
1219
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
123.3
11.5
12
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
12.3
11.4
20
17
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
36.1
11.3
14
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
11.3
114
570
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
11.2
59
200
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.5
11.0
98
461
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
18.4
10.8
16
9
J01AA02
ATC
doxycycline; systemic
2.2
10.7
334
2684
M31.0
ICD-10 Finland
Hypersensitivity angiitis
61.6
10.7
12
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
5.2
10.6
32
65
J99.8*M45
ICD-10 Finland
Respiratory disorders in ankylosing spondylitis
+∞
10.5
10
*
R03AC02
ATC
salbutamol; inhalant
2.0
10.4
231
1608
GX1K5
NOMESCO Finland
Diffusion capacity
33.5
10.4
13
*
M34.1
ICD-10 Finland
CR(E)ST syndrome
24.1
10.3
14
6
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
8.2
10.2
22
28
J05AB11
ATC
valaciclovir; oral
2.6
10.2
79
343
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
10.4
10.1
19
19
H26.3
ICD-10 Finland
Drug-induced cataract
15.1
10.1
16
11
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
15.1
10.1
16
11
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.2
9.9
30
61
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
12.6
9.9
17
14
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
9.9
93
444
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
11.0
9.9
18
17
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
9.8
67
269
KA1AE
NOMESCO Finland
Kidney ultrasound examination
8.1
9.7
21
27
H65.3
ICD-10 Finland
Chronic mucoid otitis media
8.7
9.7
20
24
A02BC01
ATC
omeprazole; systemic
2.1
9.6
139
812
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
102.3
9.5
10
*
WZC30
NOMESCO Finland
Teaching
2.6
9.4
76
334
XG466
NOMESCO Finland
Sleep oxymetry
5.5
9.4
27
52
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
9.0
9.4
19
22
SPAT1255
SPAT
Intravenous administration of medicine
3.6
9.4
42
126
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
9.3
61
238
NG1DA
NOMESCO Finland
X-ray of knees
7.6
9.3
21
29
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
6.1
9.2
24
41
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.0
9.2
36
96
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.2
9.2
34
86
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
9.4
9.1
18
20
M01CB01
ATC
sodium aurothiomalate; parenteral
10.4
9.1
17
17
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
16.0
9.1
14
9
R03AK08
ATC
formoterol and beclometasone; inhalant
4.8
9.0
29
64
J01CA04
ATC
amoxicillin; systemic
2.1
9.0
336
2771
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.6
8.9
39
115
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
6.2
8.9
23
39
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
14.4
8.7
14
10
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
14.4
8.7
14
10
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
4.0
8.7
34
91
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
16.7
8.6
13
8
A07AA02
ATC
nystatin; oral
3.3
8.6
42
135
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
10.3
8.6
16
16
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
8.5
76
355
4464A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Wegener's granulomatosis
+∞
8.4
8
*
M34
ICD-10 Finland
Systemic sclerosis
+∞
8.4
8
*
NF1AA
NOMESCO Finland
Hip X-ray examination
3.0
8.2
48
175
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
5.0
8.2
25
52
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.1
8.2
46
162
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
8.1
80
392
ZXE00
NOMESCO Finland
One hour or less
1.9
8.0
170
1130
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.7
7.9
56
228
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
13.4
7.9
13
10
H65.2
ICD-10 Finland
Chronic serous otitis media
11.1
7.8
14
13
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.1
7.8
42
145
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.1
7.8
100
550
J01DB01
ATC
cefalexin; oral
2.0
7.8
340
2863
M31.7
ICD-10 Finland
Microscopic polyangiitis
45.9
7.7
9
*
G04BE03
ATC
sildenafil; oral
7.3
7.6
17
24
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
5.8
7.5
20
36
WX002
NOMESCO Finland
Sedation and analgesia
2.1
7.4
94
513
GX1D5
NOMESCO Finland
Flow volume spirometry
81.5
7.4
8
*
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
81.5
7.4
8
*
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
8.6
7.4
15
18
GD1UN
NOMESCO Finland
Lung circulation SPECT
11.1
7.3
13
12
GD2SN
NOMESCO Finland
Lung ventilation SPECT
11.1
7.3
13
12
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
7.3
7
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.8
7.3
47
183
M05BX04
ATC
denosumab; parenteral
3.3
7.3
35
112
M01CB03
ATC
auranofin; oral
12.3
7.1
12
10
3AC01
NOMESCO Finland
NA
12.3
7.1
12
10
A01AB09
ATC
miconazole; local oral
2.6
7.1
51
210
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.3
7.1
34
109
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
7.0
42
157
Z2446
NOMESCO Finland
Social worker
3.1
7.0
39
136
ZXA10
NOMESCO Finland
Bilateral
2.0
6.9
92
510
SPAT1229
SPAT
Assessment of need for aid
2.7
6.9
48
195
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
14.1
6.9
11
8
L04AB01
ATC
etanercept; parenteral
6.9
6.9
16
24
M05BA01
ATC
etidronic acid; systemic
11.2
6.8
12
11
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
11.2
6.8
12
11
R04.2
ICD-10 Finland
Haemoptysis
4.3
6.8
24
59
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
40.7
6.8
8
*
Z3226
NOMESCO Finland
Physiotherapist
2.0
6.8
89
492
M35.3
ICD-10 Finland
Polymyalgia rheumatica
3.8
6.7
27
75
JN4CD
NOMESCO Finland
Very extensive body CT
3.9
6.7
26
70
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
22.9
6.7
9
*
M05BA06
ATC
ibandronic acid; systemic
6.1
6.7
17
29
S97
ICPC
Chronic ulcer skin
3.4
6.7
31
97
B02.9
ICD-10 Finland
Zoster without complication
3.1
6.7
35
120
N02BE01
ATC
paracetamol; systemic, rectal
2.0
6.6
353
3067
A41.9
ICD-10 Finland
Sepsis, unspecified
4.5
6.6
22
51
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
12.5
6.6
11
9
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
6.6
160
1094
R05
ICD-10 Finland
Cough
2.0
6.5
85
467
R03BB04
ATC
tiotropium bromide; inhalant
2.5
6.5
51
223
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
70.9
6.4
7
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
70.9
6.4
7
*
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.5
6.4
28
84
J47
ICD-10 Finland
Bronchiectasis
6.1
6.4
16
27
C07AB07
ATC
bisoprolol; oral
1.7
6.3
200
1469
R4120
NOMESCO Finland
Occupational therapy
3.2
6.3
32
107
H15.1
ICD-10 Finland
Episcleritis
9.5
6.3
12
13
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.8
6.3
25
69
C02KX01
ATC
bosentan; oral
+∞
6.3
6
*
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
+∞
6.3
6
*
J990, M058
ICD-10 Finland
NA
+∞
6.3
6
*
M05.3
ICD-10 Finland
Rheumatoid arthritis with involvement of other organs and systems
+∞
6.3
6
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
6.3
49
211
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
27.1
6.2
8
*
NG2CA
NOMESCO Finland
X-ray of patella with specialised projection
27.1
6.2
8
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
6.2
78
423
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.7
6.2
25
70
WX722
NOMESCO Finland
PEEP
3.7
6.2
25
70
R04.0
ICD-10 Finland
Epistaxis
2.9
6.1
36
133
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.7
6.1
40
158
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
6.1
129
839
J05AB01
ATC
aciclovir; systemic
1.9
6.1
96
568
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
10.2
6.1
11
11
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
10.2
6.1
11
11
K05.31
ICD-10 Finland
Periodontitis pronounced
2.5
6.1
48
209
Z3231
NOMESCO Finland
Registered nurse
1.8
6.0
117
741
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
6.0
65
331
Mortality – FinRegistry
↥Association
Association between endpoint RESP_ILL_DIS_CLASS_ELSEWHERE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| RESP_ILL_DIS_CLASS_ELSEWHERE | 3.745 [3.08, 4.55] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.194 |
During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 1005 females with RESP_ILL_DIS_CLASS_ELSEWHERE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| RESP_ILL_DIS_CLASS_ELSEWHERE | 3.158 [2.5, 3.98] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 342 out of 764 males with RESP_ILL_DIS_CLASS_ELSEWHERE died.
Mortality risk
Mortality risk for people of age
years, who have RESP_ILL_DIS_CLASS_ELSEWHERE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.345% | 0.573% |
| 5 | 2.154% | 3.715% |
| 10 | 5.214% | 8.745% |
| 15 | 9.821% | 16.302% |
| 20 | 17.124% | 26.876% |
Relationships between endpoints
↥Index endpoint: RESP_ILL_DIS_CLASS_ELSEWHERE – Respiratory disorders in diseases classified elsewhere
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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