This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Use of tolcapone
PDMED_TOLCAPONE
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
15 |
4. Check minimum number of events
Min. number of events
3
|
15 |
5. Include endpointsNone |
15 |
6. Filter based on genotype QC (FinnGen only) |
15 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Use of tolcapone
based on the number of shared cases.
Similar with more cases:
- Use of levodopa decarboxylase inhibitor
- Parkinson's disease, strict definition
- Parkinson's disease, strict definition, excluding more controls
- Parkinson's disease
- Parkinson's disease, excluding more controls
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 15 | - | 12 |
| Unadjusted period prevalence (%) | 0.00 | - | 0.01 |
| Median age at first event (years) | 62.85 | - | 65.25 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
0
43
0.00
1.91
0.0
3.3
—
0.7
—
0
33
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
0
39
0.00
1.64
0.0
3.4
—
1069.3
—
0
32
(3020564) Creatinine [Moles/volume] in Serum or Plasma
6
105
0.29
1.41
13.0
23.4
umol/l
62.0
85.9
—
6
105
(3020682) Albumin/Creatinine [Ratio] in Urine
0
36
0.00
1.37
0.0
3.5
—
4.7
—
0
25
(3012516) Albumin [Mass/volume] in Urine
0
32
0.00
1.35
0.0
3.1
—
1966.0
—
0
21
(3013512) EKG study
0
32
0.00
1.35
0.0
5.7
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
0
31
0.00
1.12
0.0
3.0
—
13281.2
—
0
25
(3009508) Creatinine [Moles/volume] in Urine
0
31
0.00
1.12
0.0
3.0
—
8.1
—
0
26
(1761868) Lipid panel - Serum or Plasma
0
25
0.00
0.89
0.0
3.0
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
7
40
2.39
0.88
2.6
3.1
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
7
102
0.41
0.82
8.1
18.5
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
0
19
0.00
0.65
0.0
1.1
—
2.5
—
0
8
(3044889) 12 lead EKG panel
5
74
0.52
0.54
3.0
3.7
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
0
15
0.00
0.44
0.0
5.7
—
27.0
—
0
9
(3021447) Carbon dioxide [Partial pressure] in Venous blood
0
14
0.00
0.43
0.0
4.9
—
5.7
—
0
14
(3044640) Blood type and Crossmatch panel - Blood
5
40
1.37
0.26
1.8
2.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
6
72
0.72
0.22
3.5
4.6
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
0
11
0.00
0.22
0.0
1.3
—
—
—
0
0
(4035726)
0
11
0.00
0.22
0.0
1.2
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
10
0.00
0.22
0.0
1.9
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
0
10
0.00
0.22
0.0
4.2
—
50.6
—
0
10
(3000991) Gas panel - Venous blood
0
10
0.00
0.22
0.0
11.3
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
0
10
0.00
0.22
0.0
2.1
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
10
0.00
0.22
0.0
1.2
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
0
10
0.00
0.22
0.0
3.4
—
0.2
—
0
10
(3017143) Hepatitis C virus Ab [Presence] in Serum
0
10
0.00
0.22
0.0
1.5
—
—
—
0
0
(4010399)
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
0
10
0.00
0.22
0.0
1.6
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.22
0.0
1.7
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
0
12
0.00
0.22
0.0
1.9
—
—
—
0
0
(3019225) pH of Specimen
0
12
0.00
0.22
0.0
5.4
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
0
12
0.00
0.22
0.0
3.8
—
4.1
—
0
12
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
0
12
0.00
0.22
0.0
1.7
—
4.8
—
0
12
(3004588) Protein electrophoresis panel - Serum or Plasma
0
12
0.00
0.22
0.0
1.5
—
—
—
0
0
(3009343) pH of Capillary blood
0
12
0.00
0.22
0.0
1.7
—
—
—
0
0
(3012544) pH of Venous blood
0
13
0.00
0.21
0.0
5.1
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
5
59
0.77
0.11
2.4
6.7
mmol/l
1.2
1.2
—
5
53
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
5
48
1.06
0.00
2.6
3.2
—
—
—
0
0
(3022145) Colonoscopy Study observation
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
0
6
0.00
0.00
0.0
3.8
—
1.4
—
0
6
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
0
6
0.00
0.00
0.0
3.7
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
95.4
—
0
5
(3007930) Methemoglobin/Hemoglobin.total in Blood
0
8
0.00
0.00
0.0
4.0
—
0.9
—
0
8
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000492) Spirometry study
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
4.3
—
1.6
—
0
6
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
0
8
0.00
0.00
0.0
7.9
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
4.3
—
8.3
—
0
6
(3027273) Bicarbonate [Moles/volume] in Venous blood
0
8
0.00
0.00
0.0
4.1
—
23.4
—
0
8
(3021901) Oxygen saturation in Capillary blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3028626) Oxygen [Partial pressure] in Capillary blood
0
5
0.00
0.00
0.0
1.4
—
8.4
—
0
5
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3009445) Proteinase 3 Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
5.4
—
27.4
—
0
9
(3037756) Immunofixation for Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood
0
8
0.00
0.00
0.0
4.0
—
1.6
—
0
8
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(4034850)
0
7
0.00
0.00
0.0
8.1
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
8
0.00
0.00
0.0
1.8
—
23.7
—
0
8
(1761482) Bacteria [#/volume] in Urine by Culture
0
7
0.00
0.00
0.0
6.3
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
0
8
0.00
0.00
0.0
3.9
—
136.1
—
0
8
(3022313) Gas panel - Capillary blood
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
1.0
—
0.0
—
0
5
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
0
6
0.00
0.00
0.0
3.8
—
0.8
—
0
6
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
0
6
0.00
0.00
0.0
6.0
—
25.0
—
0
6
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: PDMED_TOLCAPONE – Use of tolcapone
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).