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This is a non-core endpoint: only basic statistics are computed.

Other neonatal haemorrhages

P16_OTH_NEONTAL_HAEMORRHAGES

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P54
  • Cause of death: ICD-10 P54

2 out of 7 registries used, show all original rules.

13

4. Check minimum number of events

None

13

5. Include endpoints

None

13

6. Filter based on genotype QC (FinnGen only)

13

Control definitions (FinnGen only)

Control exclude
P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P[5-6]
Name in latin
Aliae haemorrhagiae fetales et neonatales

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1262 601 661
Only index persons 530 237 293
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population - 0.06 0.07
Only index persons 0.06 0.05 0.06

-FinnGen-

Key figures

All Female Male
Number of individuals 13 10 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 0.07 0.07 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3012095) Magnesium [Moles/volume] in Serum or Plasma
5
9
8.17
2.45
7.8
28.9
mmol/l
0.8
0.8
—
5
9
(3020779) Urea [Moles/volume] in Serum or Plasma
5
11
6.61
2.16
7.0
26.7
mmol/l
4.7
4.3
—
5
11
(3018677) aPTT in Platelet poor plasma by Coagulation assay
5
15
4.71
1.70
3.4
15.7
s
30.6
33.4
—
5
15
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
6
25
3.56
1.45
3.3
13.5
mmol/l
24.7
25.6
—
6
25
(3026008) Bacteria identified in Urine by Culture
7
36
3.02
1.21
3.0
3.1
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
6
29
2.96
1.07
11.3
10.2
g/l
41.0
37.6
—
6
29
(3044889) 12 lead EKG panel
8
47
2.80
0.88
3.6
2.1
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
13
110
+∞
0.67
18.4
10.5
mg/l
32.4
20.3
—
8
78
(40761511) CBC panel - Blood by Automated count
13
108
+∞
0.66
12.8
6.8
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
7
47
2.05
0.62
1.4
1.6
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
5
33
1.83
0.48
7.0
5.4
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
5
34
1.76
0.47
7.0
5.4
e6/l
0.0
0.1
—
5
27
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
5
34
1.76
0.47
3.0
5.6
—
—
—
0
0
(3015736) pH of Urine
6
39
1.99
0.46
2.2
4.1
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
6
40
1.92
0.46
6.3
6.1
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
0
15
0.00
0.44
0.0
7.7
—
918.3
—
0
8
(3050129) First trimester maternal screen panel - Serum or Plasma
0
14
0.00
0.44
0.0
1.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
13
113
+∞
0.44
4.8
3.8
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
0
18
0.00
0.43
0.0
1.7
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
5
37
1.57
0.28
7.0
5.6
e6/l
10.9
13.5
—
5
30
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
6
45
1.61
0.26
5.2
4.2
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
7
81
0.71
0.25
3.9
4.1
mm/h
5.9
6.2
—
7
74
(3037467) Urinalysis macro (dipstick) panel - Urine
8
67
1.50
0.24
6.3
5.2
—
—
—
0
0
(3010726) Horse dander IgE Ab [Units/volume] in Serum
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
(3021387) Prolactin [Units/volume] in Serum or Plasma
0
10
0.00
0.22
0.0
1.3
—
252.1
—
0
10
(3021960) Folate [Moles/volume] in Serum or Plasma
0
10
0.00
0.22
0.0
1.2
—
19.0
—
0
10
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
12
0.00
0.22
0.0
1.8
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
0
12
0.00
0.22
0.0
7.5
—
230.8
—
0
12
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
12
0.00
0.22
0.0
1.4
—
—
—
0
0
(3000492) Spirometry study
0
12
0.00
0.22
0.0
1.6
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
12
0.00
0.22
0.0
1.8
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
0
12
0.00
0.22
0.0
3.5
—
1.1
—
0
12
(3005719) IgG [Mass/volume] in Serum or Plasma
0
12
0.00
0.22
0.0
5.1
—
9.8
—
0
12
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
12
0.00
0.22
0.0
1.3
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
0
13
0.00
0.22
0.0
1.5
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
13
0.00
0.22
0.0
1.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
5
41
1.35
0.12
7.8
7.0
e6/l
27.9
29.6
—
5
31
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
5
59
0.75
0.11
3.0
2.0
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
0
6
0.00
0.00
0.0
8.3
—
46.7
—
0
6
(3045414) Leukocytes [Presence] in Urine
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(21494815) CD4 cells/100 lymphocytes in Specimen
0
6
0.00
0.00
0.0
3.2
—
—
—
0
0
(1175426) CD3 cells/100 lymphocytes in Blood
0
6
0.00
0.00
0.0
2.8
—
68.7
—
0
6
(3010813) Leukocytes [#/volume] in Blood
13
124
+∞
0.00
25.2
15.9
e9/l
7.0
6.5
0.28
13
119
(3006245) CD3-CD19+ cells/100 cells in Blood
0
6
0.00
0.00
0.0
1.5
—
9.2
—
0
6
(3030981) Hyaline casts [#/volume] in Urine by Automated count
0
6
0.00
0.00
0.0
5.0
—
0.0
—
0
6
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
15.8
—
0
6
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
6
58
1.06
0.00
1.3
1.8
—
0.6
—
0
13
(4010399)
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood
0
5
0.00
0.00
0.0
1.4
—
27.6
—
0
5
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(44790049)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
3.0
—
0
5
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.0
—
0.3
—
0
7
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3020393) Adenovirus Ag [Presence] in Stool
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(44790047)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
(3018133) Calcium [Moles/volume] in Urine
0
5
0.00
0.00
0.0
3.4
—
2.0
—
0
5
(3004119) Hemoglobin [Mass/volume] in Venous blood
0
7
0.00
0.00
0.0
13.1
—
126.4
—
0
7
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
0
7
0.00
0.00
0.0
13.6
—
1.1
—
0
7
(3027273) Bicarbonate [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
9.0
—
22.5
—
0
5
(44790048)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022621) pH of Urine by Test strip
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.0
—
1.5
—
0
7
(44806118)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
2.4
—
0
5
(3009445) Proteinase 3 Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_OTH_NEONTAL_HAEMORRHAGES and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_OTH_NEONTAL_HAEMORRHAGES.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_OTH_NEONTAL_HAEMORRHAGES – Other neonatal haemorrhages

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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