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This is a non-core endpoint: only basic statistics are computed.

Neonatal jaundice due to other excessive haemolysis

P16_NEONTAL_JAUND_OTH_EXCESSI_HAEMOLYS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P58
  • Cause of death: ICD-10 P58

2 out of 7 registries used, show all original rules.

14

4. Check minimum number of events

None

14

5. Include endpoints

None

14

6. Filter based on genotype QC (FinnGen only)

14

Control definitions (FinnGen only)

Control exclude
P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P[5-6]
Name in latin
Icterus neonatalis ex alia haemolysi nimia

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 771 304 467
Only index persons 516 194 322
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population - 0.00 0.00
Only index persons 0.00 0.01 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 14 8 6
Unadjusted period prevalence (%) 0.00 0.00 0.00
Median age at first event (years) 0.00 0.00 0.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3009508) Creatinine [Moles/volume] in Urine
5
21
3.12
1.20
3.2
2.5
mmol/l
9.1
10.5
—
5
21
(3041096) Erythrocytes [Presence] in Urine by Automated
0
26
0.00
0.89
0.0
2.2
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
0
17
0.00
0.43
0.0
1.2
—
118.4
—
0
10
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
8
59
1.82
0.40
2.1
1.7
mmol/l
5.3
5.1
—
8
51
(3044889) 12 lead EKG panel
5
40
1.39
0.26
3.0
1.5
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
7
55
1.54
0.24
4.4
1.6
mmol/l
4.0
4.3
—
7
50
(40761536) Microorganisms panel - Urine sediment
0
11
0.00
0.22
0.0
2.6
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
12
0.00
0.22
0.0
3.2
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
5
41
1.34
0.12
1.2
2.3
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
5
44
1.21
0.11
1.2
2.7
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
6
52
1.27
0.11
4.8
3.2
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
6
53
1.23
0.11
10.2
2.4
ug/l
180.3
43.4
—
6
48
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
6
54
1.19
0.11
4.8
1.6
mmol/l
2.5
2.6
—
6
49
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
6
54
1.19
0.11
4.3
1.5
mmol/l
1.3
1.4
—
6
49
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
5
57
0.81
0.11
2.6
1.7
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3022621) pH of Urine by Test strip
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
5
50
1.00
0.00
1.8
1.6
—
2.2
—
0
7
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3008898) HLA-B27 [Presence]
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
5
55
0.86
0.00
7.2
3.0
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3002256) Pathology report gross observation
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000492) Spirometry study
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_NEONTAL_JAUND_OTH_EXCESSI_HAEMOLYS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_NEONTAL_JAUND_OTH_EXCESSI_HAEMOLYS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_NEONTAL_JAUND_OTH_EXCESSI_HAEMOLYS – Neonatal jaundice due to other excessive haemolysis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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