This is a non-core endpoint: only basic statistics are computed.

Neonatal jaundice due to other excessive haemolysis

P16_NEONTAL_JAUND_OTH_EXCESSI_HAEMOLYS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P58 Cause of death: ICD-10 — P58 2 out of 7 registries used, show all original rules.	14
4. Check minimum number of events None	14
5. Include endpoints None	14
6. Filter based on genotype QC (FinnGen only)	14

Control definitions (FinnGen only)

Control exclude: P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P[5-6]
Name in latin: Icterus neonatalis ex alia haemolysi nimia

NAME	P16_NEONTAL_JAUND_OTH_EXCESSI_HAEMOLYS
CONTROL_EXCLUDE	P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P58
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P58
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Neonatal jaundice due to other excessive haemolysis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	771	304	467
Only index persons	516	194	322
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	-	0.00	0.00
Only index persons	0.00	0.01	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	14	8	6
Unadjusted period prevalence (%)	0.00	0.00	0.00
Median age at first event (years)	0.00	0.00	0.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(3009508) Creatinine [Moles/volume] in Urine

3.12

1.20

3.2

2.5

mmol/l

9.1

10.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

0.00

0.89

0.0

2.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

0.00

0.43

0.0

1.2

—

118.4

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

1.82

0.40

2.1

1.7

mmol/l

5.3

5.1

—

(3044889) 12 lead EKG panel

1.39

0.26

3.0

1.5

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

1.54

0.24

4.4

1.6

mmol/l

4.0

4.3

—

(40761536) Microorganisms panel - Urine sediment

0.00

0.22

0.0

2.6

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.22

0.0

3.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.34

0.12

1.2

2.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.21

0.11

1.2

2.7

—

(3031040) Bacteria [#/volume] in Urine by Automated count

1.27

0.11

4.8

3.2

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

1.23

0.11

10.2

2.4

ug/l

180.3

43.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

1.19

0.11

4.8

1.6

mmol/l

2.5

2.6

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

1.19

0.11

4.3

1.5

mmol/l

1.3

1.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.81

0.11

2.6

1.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.00

0.0

1.2

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.0

1.1

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.2

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3022621) pH of Urine by Test strip

0.00

0.0

1.6

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

1.00

0.00

1.8

1.6

—

2.2

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.4

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.0

1.8

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.0

1.8

—

(3045414) Leukocytes [Presence] in Urine

0.00

0.0

1.8

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.0

1.2

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.4

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3008898) HLA-B27 [Presence]

0.00

0.0

1.1

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.7

—

(3037467) Urinalysis macro (dipstick) panel - Urine

0.86

0.00

7.2

3.0

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.4

—

(3000330) Specific gravity of Urine by Test strip

0.00

0.0

1.7

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.7

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.4

—

(3002256) Pathology report gross observation

0.00

0.0

1.0

—

(3000492) Spirometry study

0.00

0.0

1.0

—

(3007853) Bacteria identified in Skin by Aerobe culture

0.00

0.0

1.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_NEONTAL_JAUND_OTH_EXCESSI_HAEMOLYS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_NEONTAL_JAUND_OTH_EXCESSI_HAEMOLYS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_NEONTAL_JAUND_OTH_EXCESSI_HAEMOLYS – Neonatal jaundice due to other excessive haemolysis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

Extremity

rg [CI]

Extremity

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Neonatal jaundice due to other excessive haemolysis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints