This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Intrauterine hypoxia
P16_INTRAU_HYPOXIA
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
21 |
4. Check minimum number of eventsNone |
21 |
5. Include endpointsNone |
21 |
6. Filter based on genotype QC (FinnGen only) |
21 |
Control definitions (FinnGen only)
- Control exclude
- P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- P2
- Name in latin
- Hypoxia fetus
Similar endpoints
↥List of similar endpoints to
Intrauterine hypoxia
based on the number of shared cases.
Similar with more cases:
- Respiratory and cardiovascular disorders specific to the perinatal period
- Certain conditions originating in the perinatal period
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1406 | 589 | 816 |
| Only index persons | 952 | 407 | 545 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 0.02 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 21 | 11 | 10 |
| Unadjusted period prevalence (%) | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | 10.33 | 19.72 | 0.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3021589) Normoblasts [#/volume] in Blood
5
91
0.41
0.98
10.6
6.2
e9/l
0.0
0.0
—
5
70
(3037467) Urinalysis macro (dipstick) panel - Urine
5
90
0.42
0.97
3.0
3.7
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
15
180
0.42
0.96
2.9
3.8
—
—
—
0
0
(3018418) pH of Serum or Plasma
6
32
2.22
0.90
1.2
3.0
—
7.4
—
0
6
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
12
85
1.95
0.78
2.7
2.6
mmol/mol
33.6
36.2
0.65
12
80
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
20
0.00
0.64
0.0
1.1
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
0
22
0.00
0.63
0.0
1.4
—
8.7
—
0
6
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
0
22
0.00
0.63
0.0
4.2
—
1.5
—
0
15
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
14
165
0.55
0.57
6.9
7.7
mg/l
8.9
24.7
—
9
113
(3023323) Follitropin [Units/volume] in Serum or Plasma
0
16
0.00
0.43
0.0
3.2
—
18.7
—
0
16
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
16
0.00
0.43
0.0
1.2
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
0
16
0.00
0.43
0.0
2.3
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
5
35
1.56
0.42
4.0
2.9
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
17
0.00
0.42
0.0
5.1
—
24.5
—
0
17
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
6
40
1.70
0.41
2.0
3.6
u/l
22.2
30.0
—
6
40
(40761511) CBC panel - Blood by Automated count
15
166
0.66
0.39
4.5
5.8
—
—
—
0
0
(40758558) Short blood count panel - Blood
7
53
1.48
0.36
3.0
5.1
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
7
92
0.64
0.31
1.7
1.9
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
8
102
0.65
0.31
4.5
3.2
mm/h
10.6
5.8
—
8
94
(40768804) Tissue Pathology biopsy report
5
39
1.37
0.25
1.6
1.7
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
11
0.00
0.22
0.0
1.6
—
—
—
0
0
(3020961) Endomysium IgA Ab [Titer] in Serum
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
11
0.00
0.22
0.0
1.6
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
11
0.00
0.22
0.0
1.6
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
0
11
0.00
0.22
0.0
2.9
—
95.5
—
0
11
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
11
0.00
0.22
0.0
1.6
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
0
10
0.00
0.22
0.0
3.0
—
161.1
—
0
10
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
10
0.00
0.22
0.0
1.6
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
10
0.00
0.22
0.0
1.5
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
10
0.00
0.22
0.0
1.5
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
0
10
0.00
0.22
0.0
1.3
—
96.0
—
0
5
(3001019) Free T4 and TSH panel - Serum or Plasma
0
10
0.00
0.22
0.0
3.2
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
12
0.00
0.22
0.0
1.7
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
12
0.00
0.22
0.0
2.2
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
0
14
0.00
0.21
0.0
3.6
—
190.4
—
0
14
(3036481) Cortisol [Moles/volume] in Serum or Plasma
0
14
0.00
0.21
0.0
1.5
—
279.8
—
0
14
(3028707) Methadone [Presence] in Urine by Screen method
0
14
0.00
0.21
0.0
1.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
5
63
0.73
0.20
1.0
1.9
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
5
63
0.73
0.20
1.4
1.8
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
8
96
0.73
0.19
5.9
5.2
u/l
68.9
103.5
—
8
91
(1761868) Lipid panel - Serum or Plasma
5
42
1.25
0.11
1.4
1.8
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
6
55
1.13
0.10
1.3
2.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
5
61
0.76
0.10
2.2
3.9
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
5
58
0.82
0.10
4.0
5.9
mmol/l
1.2
1.2
—
5
52
(3019550) Sodium [Moles/volume] in Serum or Plasma
15
141
1.22
0.09
4.9
7.7
mmol/l
139.6
139.6
0.00
15
136
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
15
142
1.20
0.09
3.6
3.7
mu/l
1.6
1.7
0.24
15
136
(3023103) Potassium [Moles/volume] in Serum or Plasma
15
142
1.20
0.09
4.9
7.8
mmol/l
3.7
3.9
1.91
15
136
(3044889) 12 lead EKG panel
8
75
1.11
0.09
2.3
2.1
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
9
82
1.17
0.09
6.2
5.3
%
0.5
0.7
—
9
76
(3006504) Eosinophils/100 leukocytes in Blood
9
83
1.15
0.09
6.2
5.3
%
2.4
3.2
—
9
73
(3013650) Neutrophils [#/volume] in Blood by Automated count
11
99
1.23
0.09
6.0
6.7
e9/l
4.0
3.9
0.06
11
82
(3019069) Monocytes/100 leukocytes in Blood
9
85
1.10
0.09
6.1
5.3
%
8.6
8.4
—
9
79
(3006315) Basophils [#/volume] in Blood
9
85
1.10
0.09
6.2
5.2
e9/l
0.1
0.0
—
9
69
(3013115) Eosinophils [#/volume] in Blood
9
85
1.10
0.09
6.2
5.3
e9/l
0.1
0.2
—
9
72
(3001604) Monocytes [#/volume] in Blood
9
85
1.10
0.09
6.1
5.2
e9/l
0.5
0.5
—
9
69
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
10
91
1.19
0.05
1.5
2.7
u/l
19.9
27.1
—
10
86
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
10
106
0.89
0.01
3.1
2.8
mmol/l
2.7
2.8
—
10
100
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
11
106
1.08
0.00
3.3
2.8
mmol/l
4.1
4.6
1.19
11
99
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
10
105
0.91
0.00
3.1
2.7
mmol/l
1.2
1.5
—
10
99
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
10
98
1.04
0.00
3.4
2.6
mmol/l
1.1
1.1
—
10
93
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
0
5
0.00
0.00
0.0
12.0
—
0.9
—
0
5
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
58
1.05
0.00
1.3
2.3
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
0
5
0.00
0.00
0.0
12.0
—
95.4
—
0
5
(3015235) Bicarbonate [Moles/volume] in Capillary blood
0
5
0.00
0.00
0.0
1.0
—
23.6
—
0
5
(3017044) Thyrotropin receptor Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.4
—
1.0
—
0
5
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
5
56
0.86
0.00
2.0
4.7
—
0.0
—
0
20
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
5
0.00
0.00
0.0
1.0
—
12.6
—
0
5
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
0
5
0.00
0.00
0.0
12.2
—
24.0
—
0
5
(3035637) Corticotropin [Mass/volume] in Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
5
56
0.86
0.00
3.4
3.6
—
0.0
—
0
20
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
27.4
—
0
5
(3016502) Oxygen saturation in Arterial blood
0
5
0.00
0.00
0.0
12.0
—
97.1
—
0
5
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
27.0
—
0
5
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
0
5
0.00
0.00
0.0
12.0
—
0.8
—
0
5
(40768793) Breast Pathology biopsy report
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
0
9
0.00
0.00
0.0
3.6
—
2.9
—
0
9
(3030981) Hyaline casts [#/volume] in Urine by Automated count
0
6
0.00
0.00
0.0
1.2
—
0.1
—
0
6
(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
0
7
0.00
0.00
0.0
9.0
—
16.0
—
0
7
(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.6
—
29.9
—
0
8
(3052851) Hemolysis interference index of Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
9
88
1.04
0.00
6.3
5.2
e9/l
1.7
2.1
—
9
75
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
0
8
0.00
0.00
0.0
3.4
—
1.4
—
0
8
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
0.2
—
0
7
(42529406) Shigella sp [Presence] in Stool by Culture
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
0
7
0.00
0.00
0.0
3.6
—
125.0
—
0
7
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
0
7
0.00
0.00
0.0
9.0
—
5.1
—
0
7
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(1616796) Gas panel - Central venous blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3008401) Mugwort IgE Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.1
—
6.6
—
0
8
(3003396) Base excess in Arterial blood by calculation
0
7
0.00
0.00
0.0
9.0
—
0.4
—
0
7
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
1.2
—
0
7
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
5
55
0.88
0.00
3.2
3.6
—
0.0
—
0
20
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
3.2
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
9
87
1.06
0.00
6.3
5.2
%
58.0
51.1
—
9
81
(3003327) Ova and parasites identified in Stool by Light microscopy
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint P16_INTRAU_HYPOXIA and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have P16_INTRAU_HYPOXIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: P16_INTRAU_HYPOXIA – Intrauterine hypoxia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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