This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Haemolytic disease of fetus and newborn
P16_HAEMOLYTIC_DISEA_FETUS_NEWBO
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
38 |
4. Check minimum number of eventsNone |
38 |
5. Include endpointsNone |
38 |
6. Filter based on genotype QC (FinnGen only) |
38 |
Control definitions (FinnGen only)
- Control exclude
- P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- P[5-6]
- Name in latin
- Morbus haemolyticus fetus sive neonati
Similar endpoints
↥List of similar endpoints to
Haemolytic disease of fetus and newborn
based on the number of shared cases.
Similar with more cases:
- Haemorrhagic and haematological disorders of fetus and newborn
- Certain conditions originating in the perinatal period
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2935 | 1428 | 1507 |
| Only index persons | 1452 | 693 | 759 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | - | 0.01 | 0.01 |
| Only index persons | 0.00 | 0.01 | 0.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 38 | 23 | 15 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 0.01 | 0.02 | 0.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3020961) Endomysium IgA Ab [Titer] in Serum
8
41
2.20
1.17
1.0
1.3
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
7
35
2.22
1.06
3.1
1.7
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
25
193
1.86
0.96
17.3
11.1
%
0.9
0.6
1.97
25
187
(42870588) Differential panel, method unspecified - Blood
21
155
1.79
0.92
15.8
13.2
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
15
101
1.80
0.88
26.5
8.2
umol/l
47.6
31.4
0.32
15
96
(3006504) Eosinophils/100 leukocytes in Blood
25
197
1.79
0.85
17.4
10.9
%
3.2
3.2
0.00
25
188
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
24
0.00
0.82
0.0
1.5
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
25
200
1.73
0.78
17.4
10.9
%
8.4
8.4
0.03
25
194
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
18
134
1.65
0.71
24.7
7.7
ml/min/173m2
117.6
117.0
0.03
12
86
(40758558) Short blood count panel - Blood
17
125
1.65
0.71
13.2
9.3
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
25
204
1.66
0.68
16.7
10.7
%
47.5
47.5
0.00
25
197
(36660697) Celiac disease serology panel - Serum
10
64
1.76
0.66
1.1
1.3
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
8
54
1.61
0.62
10.8
4.5
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
19
0.00
0.62
0.0
2.2
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
6
35
1.84
0.61
1.0
1.1
—
—
—
0
0
(3014576) Chloride [Moles/volume] in Serum or Plasma
6
35
1.84
0.61
6.0
23.2
mmol/l
106.5
105.2
—
6
35
(3026008) Bacteria identified in Urine by Culture
10
66
1.70
0.60
1.7
2.8
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
25
209
1.57
0.57
17.4
10.6
%
38.3
37.3
0.18
25
204
(3022948) Iron [Moles/volume] in Serum or Plasma
6
40
1.59
0.54
9.3
3.2
umol/l
15.1
14.7
—
6
40
(40761511) CBC panel - Blood by Automated count
33
299
1.79
0.53
13.8
7.5
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
15
0.00
0.42
0.0
1.6
—
—
—
0
0
(3015076) Soybean IgE Ab [Units/volume] in Serum
0
16
0.00
0.42
0.0
1.3
—
0.4
—
0
6
(3050129) First trimester maternal screen panel - Serum or Plasma
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
18
0.00
0.41
0.0
1.8
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
6
87
0.63
0.38
1.7
2.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
15
120
1.41
0.38
10.7
4.5
e6/l
244.2
71.6
—
9
83
(3007164) IgA [Mass/volume] in Serum or Plasma
17
140
1.39
0.36
1.5
1.8
g/l
1.2
1.6
—
8
71
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
8
107
0.68
0.35
21.6
4.4
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
33
306
1.59
0.29
22.2
11.6
mg/l
17.0
23.8
0.96
22
207
(3022313) Gas panel - Capillary blood
10
78
1.38
0.27
29.0
6.6
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
12
97
1.35
0.27
7.4
3.5
—
—
—
0
0
(3000570) Elastase.pancreatic [Mass/mass] in Stool
0
11
0.00
0.22
0.0
1.4
—
317.2
—
0
5
(3027901) Hemoglobin [Mass/volume] in Arterial cord blood
0
11
0.00
0.22
0.0
1.0
—
165.5
—
0
11
(3045414) Leukocytes [Presence] in Urine
0
11
0.00
0.22
0.0
1.6
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
0
10
0.00
0.22
0.0
1.6
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
6
48
1.30
0.21
2.3
1.4
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
0
12
0.00
0.21
0.0
9.3
—
—
—
0
0
(40761535) Cells panel - Urine sediment
0
12
0.00
0.21
0.0
4.8
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
0
12
0.00
0.21
0.0
9.3
—
—
—
0
0
(3027231) Wheat IgE Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3022621) pH of Urine by Test strip
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
0
13
0.00
0.21
0.0
8.6
—
224.0
—
0
13
(3009445) Proteinase 3 Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3020044) Glucose [Moles/volume] in Cerebral spinal fluid
0
13
0.00
0.21
0.0
8.6
—
3.3
—
0
13
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
15
170
0.81
0.19
18.7
4.9
u/l
112.8
131.9
0.45
15
162
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
5
67
0.71
0.19
1.2
1.8
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
8
69
1.20
0.18
2.0
3.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
9
107
0.79
0.15
1.8
1.7
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
12
104
1.22
0.14
6.2
3.0
mmol/mol
36.9
36.1
0.08
12
94
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
10
86
1.22
0.12
15.8
6.4
mmol/l
24.0
24.2
—
10
86
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
10
88
1.19
0.09
1.6
2.5
—
—
—
0
0
(3044889) 12 lead EKG panel
12
108
1.16
0.08
2.2
2.3
—
—
—
0
0
(3000991) Gas panel - Venous blood
9
83
1.11
0.08
12.9
7.7
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
9
85
1.08
0.08
30.7
10.2
mmol/l
1.5
1.4
—
9
80
(3002032) Base excess in Venous blood by calculation
8
90
0.86
0.07
12.7
12.9
mmol/l
0.1
0.6
—
8
68
(3012544) pH of Venous blood
8
92
0.84
0.07
12.9
12.8
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
9
103
0.83
0.07
18.9
15.0
mmol/l
23.9
24.9
—
9
103
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
12
109
1.15
0.07
10.4
4.0
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
14
149
0.90
0.04
8.9
3.2
ug/l
66.4
59.9
0.07
14
140
(3037467) Urinalysis macro (dipstick) panel - Urine
18
171
1.10
0.04
8.9
3.8
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
10
92
1.12
0.03
1.8
2.6
—
—
—
0
0
(3015736) pH of Urine
10
96
1.06
0.00
10.1
3.1
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
16
164
0.96
0.00
1.8
2.1
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
11
108
1.03
0.00
1.5
1.9
—
—
—
0
0
(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
92.7
—
0
6
(3023709) Somatotropin [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
5.2
—
3.0
—
0
6
(3014051) Protein [Presence] in Urine by Test strip
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3016038) Potassium [Moles/volume] in Urine
0
6
0.00
0.00
0.0
2.7
—
35.0
—
0
6
(3022411) Androstenedione [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.8
—
3.8
—
0
6
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
0
8
0.00
0.00
0.0
2.6
—
1.7
—
0
8
(4268621)
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
33
328
1.05
0.00
5.2
3.8
—
—
—
0
0
(3022229) Phosphate [Moles/volume] in Urine
0
5
0.00
0.00
0.0
4.2
—
14.8
—
0
5
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
26.4
—
0
5
(3042299) inFLIXimab [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
10.6
—
7.1
—
0
8
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(4198724)
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016616) Dehydroepiandrosterone sulfate (DHEA-S) [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.6
—
4.3
—
0
8
(40768453) Hazelnut native (nCor a) 9 IgE Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.4
—
1.0
—
0
7
(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
0.3
—
0
5
(3016031) Almond IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
5.2
—
0
5
(3018133) Calcium [Moles/volume] in Urine
0
8
0.00
0.00
0.0
3.1
—
2.0
—
0
8
(3017115) Methotrexate [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
28.9
—
0.7
—
0
7
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
0
8
0.00
0.00
0.0
11.8
—
—
—
0
0
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.6
—
16.4
—
0
9
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009466) Valproate [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
5.6
—
457.3
—
0
9
(3044640) Blood type and Crossmatch panel - Blood
7
73
0.95
0.00
22.3
3.8
—
—
—
0
0
(3032352) Blasts [#/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
7.1
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4062490)
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
5
50
1.00
0.00
3.8
4.7
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
6
60
1.00
0.00
23.3
4.1
—
—
—
0
0
(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
74.0
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint P16_HAEMOLYTIC_DISEA_FETUS_NEWBO and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have P16_HAEMOLYTIC_DISEA_FETUS_NEWBO.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: P16_HAEMOLYTIC_DISEA_FETUS_NEWBO – Haemolytic disease of fetus and newborn
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data