Fetus and newborn affected by maternal conditions that may be unrelated to present pregnancy

P16_FET_NEWB_MATERN_COND_UNREL_PRESENT_PREGNAC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P00
  • Cause of death: ICD-10 P00

2 out of 7 registries used, show all original rules.

145

4. Check minimum number of events

None

145

5. Include endpoints

None

145

6. Filter based on genotype QC (FinnGen only)

145

Control definitions (FinnGen only)

Control exclude
P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P0[0-4]
Name in latin
Fetus et neonatus condicionibus matris (etiam ad graviditatem praesentem non pertinentibus) affectus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10861 5151 5709
Only index persons 4967 2381 2586
Unadjusted period prevalence (%)
Whole population 0.15 0.15 0.16
Only index persons 0.09 0.09 0.10
Median age at first event (years)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 145 71 74
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
130
Matched controls
1301
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
+∞
110.8
90
*
P07.3
ICD-10 Finland
Other preterm infants
25.1
39.0
57
39
P00.8
ICD-10 Finland
Fetus and newborn affected by other maternal conditions
+∞
23.7
22
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
13.1
22.3
41
44
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
12.4
15.4
28
28
P00.2
ICD-10 Finland
Fetus and newborn affected by maternal infectious and parasitic diseases
+∞
12.7
12
*
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
25.9
10.5
14
6
P05.0
ICD-10 Finland
Light for gestational age
22.2
10.0
14
7
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
+∞
8.4
8
*
P05.1
ICD-10 Finland
Small for gestational age
11.9
7.5
13
12
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
13.1
7.2
12
10
P70.0
ICD-10 Finland
Syndrome of infant of mother with gestational diabetes
10.9
6.7
12
12
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
7.2
6.6
15
23
P01.10
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes 1-7 days before delivery
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3022411) Androstenedione [Moles/volume] in Serum or Plasma
7
15
4.82
2.62
1.4
2.9
nmol/l
3.3
2.4
—
7
15
(3026820) Hemoglobin [Mass/volume] in Venous cord blood
5
8
6.40
2.38
1.0
1.0
g/l
168.0
154.3
—
5
8
(40765089) Chromosome analysis panel - Blood by G-banded
7
19
3.80
2.17
1.0
1.1
—
—
—
0
0
(3022670) pH of Venous cord blood
6
17
3.62
1.85
1.0
1.0
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
17
91
1.97
1.67
1.4
1.5
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
5
14
3.64
1.62
1.0
1.6
—
—
—
0
0
(3023709) Somatotropin [Mass/volume] in Serum or Plasma
8
32
2.57
1.61
5.8
6.1
ug/l
1.9
2.3
—
8
32
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
8
163
0.46
1.47
2.0
2.1
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
13
231
0.52
1.47
2.5
3.1
kg/l
1.0
1.0
—
6
46
(3003694) ABO and Rh group [Type] in Blood
23
337
0.62
1.29
1.6
1.6
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
8
146
0.52
1.11
1.3
2.0
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
9
157
0.54
1.06
1.2
2.0
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
6
118
0.49
0.99
1.5
2.6
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
0
28
0.00
0.99
0.0
2.6
—
1.7
—
0
28
(3008757) Leukocyte morphology finding [Identifier] in Blood
0
32
0.00
0.96
0.0
5.8
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
13
78
1.72
0.94
2.2
2.4
nmol/l
6.1
10.9
—
8
59
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
8
42
1.95
0.90
1.9
2.0
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
19
267
0.66
0.87
2.3
3.4
ug/g
73.9
78.2
0.05
14
210
(40760892) CBC W Ordered Manual Differential panel - Blood
16
233
0.64
0.87
5.3
6.0
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
7
124
0.54
0.82
1.3
2.1
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
10
159
0.60
0.78
1.2
2.0
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
10
159
0.60
0.78
1.2
1.9
—
—
—
0
0
(3020891) Body temperature
0
27
0.00
0.78
0.0
11.1
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
27
0.00
0.78
0.0
3.7
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
27
0.00
0.78
0.0
3.7
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
10
158
0.60
0.77
1.2
2.0
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
11
169
0.62
0.76
1.6
1.7
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
22
292
0.71
0.75
2.3
2.1
—
—
—
0
0
(3023323) Follitropin [Units/volume] in Serum or Plasma
14
93
1.55
0.71
2.7
2.5
iu/l
4.4
7.5
—
7
61
(3048929) Epstein Barr virus Ab [Presence] in Serum
13
189
0.65
0.71
1.4
1.8
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
111
1174
0.75
0.69
16.2
17.1
%
39.8
38.9
1.44
104
1045
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
21
277
0.71
0.69
2.6
3.6
—
—
—
0
0
(3027901) Hemoglobin [Mass/volume] in Arterial cord blood
7
43
1.65
0.67
1.0
1.0
g/l
173.6
161.4
—
7
43
(3005322) IgE [Units/volume] in Serum or Plasma
10
152
0.63
0.66
2.4
1.5
u/ml
161.3
414.6
—
10
138
(3009214) Lutropin [Units/volume] in Serum or Plasma
15
104
1.49
0.64
2.6
2.5
u/l
6.7
5.7
—
7
71
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
20
262
0.72
0.63
2.1
2.5
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
52
597
0.79
0.63
5.5
4.1
—
35.9
—
0
8
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
20
0.00
0.61
0.0
1.7
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
0
20
0.00
0.61
0.0
5.6
—
1.5
—
0
20
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
21
0.00
0.60
0.0
7.0
—
—
—
0
0
(3029493) Herpes virus 6 DNA [Presence] in Blood by NAA with probe detection
0
21
0.00
0.60
0.0
5.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
29
356
0.76
0.60
3.1
4.9
—
—
—
0
0
(3027653) Mycophenolate [Mass/volume] in Serum or Plasma
0
22
0.00
0.60
0.0
9.2
—
2.1
—
0
17
(3042936) Bacteria identified in Isolate by Culture
8
121
0.64
0.57
1.6
1.8
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
12
169
0.68
0.57
2.8
1.8
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
90
823
1.23
0.56
3.4
3.3
pmol/l
14.2
14.5
0.53
85
755
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
22
278
0.75
0.56
2.2
2.6
—
—
—
0
0
(40758558) Short blood count panel - Blood
37
436
0.79
0.55
8.0
9.9
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
14
190
0.71
0.55
2.0
2.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
15
200
0.72
0.53
2.4
1.6
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
67
737
0.82
0.51
6.9
11.1
e9/l
2.6
2.4
0.57
54
618
(3044889) 12 lead EKG panel
47
406
1.23
0.50
2.0
2.3
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
49
553
0.82
0.48
1.5
1.9
u/ml
2.0
3.2
—
7
90
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
12
85
1.44
0.47
1.0
1.3
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
5
84
0.58
0.47
2.0
1.8
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
7
49
1.44
0.46
1.1
1.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
57
632
0.83
0.46
4.8
4.4
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
12
162
0.71
0.46
2.0
1.6
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
39
448
0.82
0.46
3.7
3.6
estimate
0.0
0.0
—
5
76
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
9
126
0.69
0.45
3.9
9.7
%
91.3
89.0
—
9
126
(3005719) IgG [Mass/volume] in Serum or Plasma
11
150
0.71
0.45
1.8
4.4
g/l
9.8
8.5
0.84
11
144
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
14
183
0.74
0.45
2.0
2.2
mmol/l
1.2
1.4
0.69
14
170
(4010399)
8
56
1.45
0.43
1.8
1.5
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
39
445
0.83
0.42
6.1
5.2
estimate
0.0
0.0
—
5
80
(3007164) IgA [Mass/volume] in Serum or Plasma
47
526
0.84
0.41
1.5
1.7
g/l
1.6
1.5
0.04
16
255
(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
5
33
1.53
0.41
1.4
1.5
—
—
—
0
0
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
5
33
1.53
0.41
6.4
3.8
umol/l
23.0
27.6
—
5
33
(3032185) JC virus DNA [#/volume] (viral load) in Serum or Plasma by NAA with probe detection
0
15
0.00
0.41
0.0
7.4
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
0
16
0.00
0.41
0.0
4.1
—
—
—
0
0
(3004959) Base excess in Arterial cord blood by calculation
11
79
1.42
0.41
1.0
1.0
mmol/l
-4.4
-3.0
—
5
33
(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood
11
79
1.42
0.41
1.0
1.0
mmol/l
18.1
19.5
0.62
11
79
(3006598) pH of Arterial cord blood
11
79
1.42
0.41
1.0
1.0
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
7
105
0.65
0.41
1.0
2.0
—
—
—
0
0
(3020961) Endomysium IgA Ab [Titer] in Serum
14
180
0.75
0.40
1.1
1.4
—
47.5
—
0
6
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
5
34
1.48
0.40
2.4
1.8
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
(3024932) HLA-DR beta [Type]
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
(3024471) HLA-A [Type]
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
(3003752) BK virus DNA [Units/volume] (viral load) in Urine by NAA with probe detection
0
19
0.00
0.39
0.0
6.6
—
—
—
0
0
(3032390) JC virus DNA [#/volume] (viral load) in Urine by NAA with probe detection
0
19
0.00
0.39
0.0
6.6
—
—
—
0
0
(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay
5
36
1.40
0.38
1.0
1.1
—
4.1
—
0
11
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
5
36
1.40
0.38
2.6
1.9
—
—
—
0
0
(3000991) Gas panel - Venous blood
32
273
1.21
0.38
8.0
14.7
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
67
723
0.86
0.37
6.9
11.1
e9/l
0.6
0.6
0.41
52
584
(3003740) Influenza virus B Ag [Presence] in Specimen
6
41
1.48
0.36
1.2
1.2
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
5
80
0.61
0.36
1.4
2.2
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
6
42
1.44
0.36
1.2
1.2
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
67
721
0.86
0.35
6.9
11.1
e9/l
0.0
0.0
0.32
52
583
(21494755) Public health laboratory ask at order entry panel
6
44
1.37
0.35
1.0
1.1
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
10
74
1.37
0.32
2.2
1.9
—
—
—
0
0
(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum
7
51
1.39
0.32
1.1
1.1
—
4.4
—
0
7
(3013650) Neutrophils [#/volume] in Blood by Automated count
71
756
0.87
0.31
7.9
13.3
e9/l
3.4
3.4
0.06
54
621
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
7
53
1.33
0.31
2.1
2.1
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
109
1127
0.85
0.31
12.4
12.2
mg/l
25.0
23.8
0.11
76
742
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
8
105
0.74
0.30
3.4
8.4
%
121.3
173.7
—
8
105
(3026493) Urate [Moles/volume] in Serum or Plasma
9
117
0.75
0.28
2.1
7.0
umol/l
287.2
274.2
—
9
109
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
61
563
1.14
0.28
16.0
14.2
mmol/l
1.2
1.2
0.11
56
525
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
20
168
1.22
0.28
2.1
6.8
mg/l
1.1
2.1
0.75
13
123
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
8
64
1.26
0.28
1.0
1.1
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
10
127
0.77
0.27
1.4
1.4
%
1.3
1.4
—
10
114
(3011397) Hemoglobin [Presence] in Urine by Test strip
25
285
0.85
0.27
4.2
3.4
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
30
264
1.17
0.26
2.2
4.3
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
18
211
0.83
0.26
3.2
4.5
inr
1.1
1.2
—
7
57
(3025941) Bacteria identified in Stool by Culture
5
37
1.36
0.24
1.2
1.4
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
5
38
1.32
0.23
1.4
1.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
39
354
1.13
0.23
5.6
4.8
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
15
125
1.22
0.22
3.1
2.7
ng/l
8.1
18.3
—
8
52
(3009445) Proteinase 3 Ab [Units/volume] in Serum
5
40
1.25
0.22
1.2
1.4
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
21
182
1.17
0.22
5.6
4.9
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
55
585
0.90
0.22
2.4
2.0
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
10
123
0.80
0.22
1.9
2.2
g/l
1.0
0.9
—
10
116
(3013512) EKG study
8
101
0.78
0.22
2.1
2.8
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
5
42
1.19
0.21
1.4
1.2
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
18
207
0.85
0.21
2.1
1.7
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3041672) Baker's yeast Ab [Presence] in Serum
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3000475) Leukocytes [#/volume] in Synovial fluid
0
11
0.00
0.21
0.0
1.2
—
4567.2
—
0
6
(3044941) Cell count panel - Synovial fluid
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
12
0.00
0.21
0.0
3.6
—
31.3
—
0
12
(42869858) Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3032352) Blasts [#/volume] in Cerebral spinal fluid
0
12
0.00
0.21
0.0
9.1
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3017115) Methotrexate [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
27.2
—
0.6
—
0
12
(3013115) Eosinophils [#/volume] in Blood
70
734
0.90
0.21
7.6
12.0
e9/l
0.2
0.2
1.15
57
611
(3021589) Normoblasts [#/volume] in Blood
67
704
0.90
0.21
9.2
12.9
e9/l
0.0
0.0
0.50
46
517
(3015736) pH of Urine
33
361
0.88
0.21
3.5
3.4
—
—
—
0
0
(3005011) Chlamydia sp Ab [Titer] in Serum
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
13
0.00
0.21
0.0
3.3
—
—
—
0
0
(3008092) Baker's yeast IgG Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.5
—
16.4
—
0
5
(3027300) Silver Birch IgE Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
48
1.26
0.20
10.2
25.8
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
16
185
0.84
0.20
2.2
3.4
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
(3036071) Salmonella sp Ab [Titer] in Serum
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(4035726)
6
50
1.20
0.20
1.5
2.1
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
6
51
1.18
0.19
2.3
1.9
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
56
591
0.91
0.19
2.1
2.2
mmol/l
5.4
5.4
0.04
50
543
(3023511) Choriogonadotropin [Units/volume] in Urine
7
59
1.19
0.18
1.3
1.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
7
60
1.17
0.18
1.3
1.4
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
6
76
0.78
0.16
1.5
1.7
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
50
527
0.92
0.16
6.2
7.4
ml/min/173m2
114.8
114.7
0.02
35
310
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
6
79
0.75
0.16
1.5
2.0
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
15
130
1.17
0.15
2.5
2.1
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
7
88
0.78
0.15
2.0
1.6
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
69
715
0.93
0.14
6.9
11.3
%
8.4
8.5
0.16
64
690
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
11
93
1.19
0.14
1.0
1.2
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
38
354
1.09
0.14
5.8
4.8
e6/l
0.0
0.2
2.18
27
256
(3024561) Albumin [Mass/volume] in Serum or Plasma
31
330
0.92
0.12
8.4
10.5
g/l
35.5
37.3
0.80
31
318
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
13
146
0.88
0.11
4.2
8.5
umol/l
6.6
8.0
—
7
125
(3022313) Gas panel - Capillary blood
30
279
1.09
0.11
20.0
10.2
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
36
339
1.08
0.10
20.6
16.5
mmol/l
24.8
24.8
0.03
36
339
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
18
196
0.90
0.10
1.4
3.2
u/l
69.3
64.5
0.10
18
180
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
5
43
1.16
0.10
3.4
1.3
—
—
—
0
0
(44790049)
5
43
1.16
0.10
1.2
2.0
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
5
43
1.16
0.10
3.4
1.3
—
—
—
0
0
(44806118)
5
43
1.16
0.10
1.2
2.0
—
—
—
0
0
(44790047)
5
43
1.16
0.10
1.2
2.0
—
—
—
0
0
(44790048)
5
43
1.16
0.10
1.2
2.0
—
—
—
0
0
(21494815) CD4 cells/100 lymphocytes in Specimen
5
44
1.14
0.10
3.0
4.3
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
40
379
1.07
0.10
5.5
5.0
e6/l
17.0
29.3
0.47
29
283
(3001405) CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood
5
46
1.09
0.09
3.0
3.8
e6/l
572.0
533.4
—
5
29
(3025271) CD3-CD16+CD56+ (Natural killer) cells [#/volume] in Blood
5
46
1.09
0.09
3.0
3.8
e9/l
0.6
0.2
—
5
29
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
5
47
1.06
0.09
2.0
2.3
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
5
47
1.06
0.09
3.0
4.2
—
—
—
0
0
(3011412) CD3 cells [#/volume] in Blood
5
47
1.06
0.09
3.0
4.2
e9/l
1.8
1.6
—
5
30
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
33
311
1.07
0.09
19.4
10.7
mmol/l
1.3
1.2
0.11
22
227
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
6
54
1.11
0.09
12.0
25.9
mmol/l
22.8
24.5
—
6
54
(3047007) Chlamydophila sp Ab [Presence] in Serum
6
55
1.09
0.09
1.2
1.1
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
5
62
0.80
0.08
4.0
2.5
pmol/l
5.9
5.2
—
5
54
(3009508) Creatinine [Moles/volume] in Urine
26
275
0.93
0.08
2.7
5.1
mmol/l
9.2
8.7
0.15
26
265
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
7
64
1.09
0.08
2.3
1.8
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
7
64
1.09
0.08
1.1
1.1
—
—
—
0
0
(3000492) Spirometry study
6
71
0.83
0.08
2.0
1.5
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
6
74
0.80
0.08
3.2
3.6
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
119
1200
0.93
0.07
3.9
3.7
—
—
—
0
0
(3009343) pH of Capillary blood
33
313
1.06
0.07
19.4
10.8
—
7.4
—
0
12
(3020779) Urea [Moles/volume] in Serum or Plasma
18
193
0.92
0.07
9.4
14.3
mmol/l
4.9
4.9
0.02
18
188
(3023520) Reticulocytes [#/volume] in Blood
15
137
1.10
0.07
3.3
6.4
e9/l
55.9
62.7
—
9
89
(3000494) Fungus identified in Specimen by Culture
9
99
0.90
0.06
6.0
1.9
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
18
191
0.93
0.05
2.4
1.6
pmol/l
84.4
97.4
—
6
100
(3003338) MCHC [Mass/volume]
112
1128
0.95
0.05
15.1
16.8
g/l
336.8
335.5
0.81
112
1111
(3018095) Leukocytes [#/volume] in Urine
45
436
1.04
0.04
6.8
5.9
e6/l
51.7
33.8
0.21
30
290
(1761868) Lipid panel - Serum or Plasma
16
169
0.94
0.04
1.8
2.0
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
16
169
0.94
0.04
1.1
1.1
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
22
229
0.95
0.03
4.6
2.5
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
109
1096
0.96
0.03
8.7
7.8
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
14
131
1.07
0.03
2.6
2.0
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
24
230
1.05
0.03
5.4
4.4
e6/l
0.7
0.6
0.11
13
125
(3002385) Erythrocyte distribution width [Ratio]
110
1105
0.96
0.03
16.2
17.8
%
13.3
13.1
0.44
110
1088
(3020682) Albumin/Creatinine [Ratio] in Urine
10
93
1.08
0.01
3.8
4.1
mg/mmol
8.5
10.3
—
10
84
(42870588) Differential panel, method unspecified - Blood
58
584
0.98
0.01
6.9
11.5
—
—
—
0
0
(3027945) Reticulocytes/100 erythrocytes in Blood
18
185
0.96
0.00
3.6
9.2
%
1.7
1.3
0.55
18
179
(3007461) Platelets [#/volume] in Blood
130
1289
1.04
0.00
15.7
17.6
e9/l
274.4
273.0
0.08
120
1216
(3012516) Albumin [Mass/volume] in Urine
10
94
1.06
0.00
2.8
3.6
mg/l
81.0
138.8
—
10
84
(3010813) Leukocytes [#/volume] in Blood
130
1291
1.03
0.00
15.6
17.5
e9/l
7.2
6.9
0.92
119
1210
(36660697) Celiac disease serology panel - Serum
24
237
1.01
0.00
1.3
1.3
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
23
233
0.98
0.00
2.4
4.1
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
40
401
0.99
0.00
5.6
5.0
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
34
344
0.98
0.00
1.9
2.0
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
15
154
0.97
0.00
2.6
2.0
—
—
—
0
0
(3026361) Erythrocytes [#/volume] in Blood
130
1290
1.03
0.00
15.6
17.5
e12/l
4.7
4.6
1.49
120
1213
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
24
235
1.02
0.00
5.4
4.4
e6/l
0.7
1.9
1.38
13
132
(723473) SARS-CoV-2 (COVID-19) IgA Ab [Presence] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(1001833) Epstein Barr virus DNA [Units/volume] (viral load) in Blood by NAA with probe detection
0
7
0.00
0.00
0.0
7.9
—
—
—
0
0
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
5
55
0.90
0.00
14.2
25.7
%
98.0
95.1
—
5
55
(40758292) HTLV I+II Ab panel - Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
9.5
—
0
8
(40768793) Breast Pathology biopsy report
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029536) Hepatitis C virus RNA [Units/volume] (viral load) in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3040893) Potassium [Moles/volume] in Capillary blood
0
7
0.00
0.00
0.0
5.0
—
4.2
—
0
7
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.0
—
9.5
—
0
9
(3027305) Fractional oxyhemoglobin in Arterial cord blood
0
5
0.00
0.00
0.0
1.0
—
33.5
—
0
5
(3024891) Influenza virus A+B Ag [Presence] in Specimen
6
68
0.87
0.00
2.8
1.2
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
6
66
0.90
0.00
1.7
1.5
—
—
—
0
0
(3032868) Hemoglobin electrophoresis panel in Blood
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(21491979) Prolactin monomeric [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
435.5
—
0
6
(3045788) Cell count panel - Pleural fluid
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(723474) SARS-CoV-2 (COVID-19) IgG Ab [Presence] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3035401) Herpes virus 6 DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
5.3
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3041806) Other cells [#/volume] in Blood by Manual count
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40760512) CD34 cells/100 cells in Bone marrow
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
(3014038) Collagen crosslinked N-telopeptide [Moles/volume] in Urine
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3035999) Lactate [Moles/volume] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.8
—
1.4
—
0
8
(3009410) PHENobarbital [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
15.6
—
97.0
—
0
5
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
5
58
0.85
0.00
14.2
24.5
%
0.7
0.7
—
5
58
(3031309) Prolactin monomeric/Prolactin.total in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
76.3
—
0
6
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
7
0.00
0.00
0.0
8.6
—
—
—
0
0
(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3000012) Reticulocyte production index
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma
0
9
0.00
0.00
0.0
1.0
—
109.9
—
0
9
(3032641) Amino acids panel - Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
5
58
0.85
0.00
14.2
24.5
%
0.8
1.1
—
5
58
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
7
76
0.91
0.00
2.1
2.1
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3017315) Amylase [Enzymatic activity/volume] in Urine
0
5
0.00
0.00
0.0
1.8
—
134.6
—
0
5
(3014043) Spermatozoa Nonprogressive/100 spermatozoa in Semen
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40761995) Spermatozoa Progressive [#/volume] in Semen
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3012320) Pathologist interpretation of Cerebral spinal fluid tests
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(3008860) Bordetella pertussis IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3000060) B lymphocytes [#/volume] in Blood
5
51
0.98
0.00
3.0
3.7
e6/l
714.0
404.1
—
5
32
(3004716) Salmonella sp identified in Stool by Organism specific culture
9
94
0.95
0.00
1.2
1.1
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
3.8
—
0
5

Mortality – FinRegistry

Association

Association between endpoint P16_FET_NEWB_MATERN_COND_UNREL_PRESENT_PREGNAC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FET_NEWB_MATERN_COND_UNREL_PRESENT_PREGNAC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_FET_NEWB_MATERN_COND_UNREL_PRESENT_PREGNAC – Fetus and newborn affected by maternal conditions that may be unrelated to present pregnancy

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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