info icon

Fetal blood loss

P16_FETAL_BLOOD_LOSS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P50
  • Cause of death: ICD-10 P50

2 out of 7 registries used, show all original rules.

21

4. Check minimum number of events

None

21

5. Include endpoints

None

21

6. Filter based on genotype QC (FinnGen only)

21

Control definitions (FinnGen only)

Control exclude
P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P[5-6]
Name in latin
Haemorrhagia fetalis

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1015 518 496
Only index persons 522 260 262
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 0.04 0.00 0.00
Only index persons 0.00 0.00 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 21 13 8
Unadjusted period prevalence (%) 0.00 0.00 0.00
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3020779) Urea [Moles/volume] in Serum or Plasma
6
21
3.57
1.64
13.2
12.8
mmol/l
5.8
4.2
—
6
21
(3026782) Osmolality of Urine
6
24
3.08
1.42
7.0
3.2
mosm/kgh2o
622.5
638.9
—
6
19
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
5
18
3.31
1.37
1.8
2.6
—
7.8
—
0
9
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
7
32
2.77
1.22
3.9
3.5
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
5
22
2.66
1.10
6.6
4.9
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
6
28
2.59
1.01
9.8
2.3
e6/l
8.0
9.2
—
6
23
(1761868) Lipid panel - Serum or Plasma
6
28
2.59
1.01
2.3
1.5
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
8
44
2.31
1.01
2.4
2.8
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
6
30
2.39
0.96
1.5
10.0
s
37.7
30.5
—
6
30
(3013115) Eosinophils [#/volume] in Blood
14
101
2.15
0.94
10.2
10.1
e9/l
0.2
0.2
0.39
14
83
(3041096) Erythrocytes [Presence] in Urine by Automated
6
32
2.22
0.90
4.7
2.2
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
7
40
2.12
0.82
5.6
3.1
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
5
88
0.43
0.80
1.6
1.5
—
0.4
—
0
13
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
9
58
1.96
0.69
7.1
4.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
9
59
1.91
0.68
4.9
3.8
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
6
34
2.06
0.66
4.8
4.2
—
—
—
0
0
(3012544) pH of Venous blood
6
37
1.86
0.62
2.2
11.3
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
6
37
1.86
0.62
2.2
11.3
kpa
5.8
6.0
—
6
37
(3006315) Basophils [#/volume] in Blood
13
98
1.85
0.60
10.7
9.4
e9/l
0.0
0.0
0.20
13
80
(3019198) Lymphocytes [#/volume] in Blood
13
100
1.78
0.59
11.2
9.3
e9/l
2.2
2.2
0.02
13
84
(3037467) Urinalysis macro (dipstick) panel - Urine
13
100
1.78
0.59
6.9
3.6
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
7
44
1.88
0.57
2.1
2.6
—
—
—
0
0
(3044889) 12 lead EKG panel
10
70
1.82
0.55
2.7
2.0
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
7
48
1.68
0.54
4.3
3.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
7
48
1.68
0.54
6.7
3.3
—
—
—
0
0
(40758558) Short blood count panel - Blood
8
59
1.57
0.49
21.6
10.1
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
16
180
0.54
0.48
4.5
4.0
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
7
96
0.60
0.45
1.4
2.0
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
5
34
1.61
0.44
2.4
11.3
kpa
5.8
5.1
—
5
34
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
12
97
1.55
0.44
4.1
2.4
mmol/l
1.1
1.1
0.03
12
90
(3001604) Monocytes [#/volume] in Blood
12
98
1.52
0.43
11.5
9.4
e9/l
0.5
0.5
0.24
12
79
(3050129) First trimester maternal screen panel - Serum or Plasma
0
17
0.00
0.42
0.0
1.4
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
0
18
0.00
0.42
0.0
1.1
—
1275.1
—
0
18
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
6
40
1.70
0.41
2.2
2.3
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
8
60
1.54
0.35
2.0
1.6
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
5
71
0.61
0.33
2.8
2.1
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
8
64
1.40
0.33
4.1
3.5
nmol/l
70.9
66.7
—
8
58
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
13
109
1.50
0.31
5.6
2.1
mmol/l
5.5
5.5
0.01
13
95
(3002030) Lymphocytes/100 leukocytes in Blood
12
100
1.46
0.31
11.8
8.8
%
34.5
35.4
0.09
12
95
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
6
49
1.31
0.23
3.2
3.9
mg/l
1.3
2.6
—
6
43
(3004119) Hemoglobin [Mass/volume] in Venous blood
0
11
0.00
0.22
0.0
13.4
—
127.7
—
0
11
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
11
0.00
0.22
0.0
1.7
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
0
10
0.00
0.22
0.0
14.5
—
1.1
—
0
10
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
0
10
0.00
0.22
0.0
2.0
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
10
0.00
0.22
0.0
2.0
—
—
—
0
0
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
0
10
0.00
0.22
0.0
7.8
—
5.0
—
0
10
(3027801) Oxygen [Partial pressure] in Arterial blood
0
10
0.00
0.22
0.0
7.5
—
19.5
—
0
10
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
0
10
0.00
0.22
0.0
1.9
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
10
0.00
0.22
0.0
1.4
—
—
—
0
0
(3008898) HLA-B27 [Presence]
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
12
0.00
0.22
0.0
1.3
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3015736) pH of Urine
7
60
1.25
0.21
4.0
3.1
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
7
60
1.25
0.21
2.3
2.8
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
9
79
1.24
0.19
14.7
10.8
mmol/l
1.2
1.2
—
9
70
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
10
85
1.34
0.16
18.3
5.0
u/l
108.4
106.8
—
10
80
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
10
87
1.29
0.12
4.1
2.6
mmol/mol
34.7
35.3
—
10
79
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
5
42
1.25
0.11
13.0
12.0
mmol/l
24.0
24.7
—
5
42
(36660697) Celiac disease serology panel - Serum
5
44
1.18
0.11
1.2
1.1
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
11
98
1.26
0.10
12.5
8.7
%
2.3
2.9
0.67
11
90
(3019069) Monocytes/100 leukocytes in Blood
11
98
1.26
0.10
13.5
8.9
%
8.2
8.3
0.04
11
93
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
15
156
0.87
0.10
4.9
3.1
mu/l
2.7
1.8
1.56
15
145
(3019550) Sodium [Moles/volume] in Serum or Plasma
16
148
1.34
0.10
18.1
12.5
mmol/l
139.4
139.3
0.19
16
143
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
7
79
0.83
0.09
20.6
11.5
mmol/l
1.2
1.2
—
7
74
(42870588) Differential panel, method unspecified - Blood
8
75
1.11
0.09
10.5
10.5
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
9
82
1.17
0.09
14.7
7.2
mmol/l
5.9
5.9
—
9
77
(3018010) Neutrophils/100 leukocytes in Blood
11
100
1.21
0.07
13.2
8.7
%
50.5
49.8
0.06
11
94
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
11
104
1.12
0.01
3.7
2.5
mmol/l
1.3
1.4
0.45
11
94
(3013707) Erythrocyte sedimentation rate by Westergren method
11
113
0.94
0.00
5.6
4.3
mm/h
11.8
7.5
0.46
11
106
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
11
105
1.10
0.00
3.8
2.5
mmol/l
2.9
2.7
0.22
11
95
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
11
105
1.10
0.00
3.7
2.6
mmol/l
4.4
4.5
0.05
11
95
(3021589) Normoblasts [#/volume] in Blood
10
102
0.96
0.00
10.9
10.3
e9/l
0.0
0.0
—
10
77
(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
7.2
—
89.6
—
0
5
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
0
5
0.00
0.00
0.0
10.0
—
51.0
—
0
5
(3022493) Free Hemoglobin [Mass/volume] in Plasma
0
5
0.00
0.00
0.0
3.4
—
181.0
—
0
5
(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
5.5
—
0
5
(4268621)
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3019225) pH of Specimen
0
6
0.00
0.00
0.0
7.8
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
0
7
0.00
0.00
0.0
8.0
—
24.9
—
0
7
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3016921) Smith extractable nuclear Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
5
50
1.00
0.00
2.2
1.8
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
0
7
0.00
0.00
0.0
10.1
—
96.3
—
0
7
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
0
7
0.00
0.00
0.0
10.1
—
0.6
—
0
7
(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002173) Hemoglobin [Mass/volume] in Arterial blood
0
7
0.00
0.00
0.0
10.7
—
123.6
—
0
7
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3020393) Adenovirus Ag [Presence] in Stool
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
4.9
—
324.0
—
0
7
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
0
7
0.00
0.00
0.0
10.1
—
0.9
—
0
7
(3016502) Oxygen saturation in Arterial blood
0
8
0.00
0.00
0.0
9.5
—
98.0
—
0
8
(3019230) Fractional oxyhemoglobin in Venous blood
0
6
0.00
0.00
0.0
15.8
—
76.8
—
0
6
(3006598) pH of Arterial cord blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3039162) Centromere protein B Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
9
88
1.04
0.00
4.1
3.6
ug/l
131.8
35.0
—
9
80
(3021706) Oxygen [Partial pressure] in Arterial cord blood
0
6
0.00
0.00
0.0
1.0
—
3.4
—
0
6
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
0
7
0.00
0.00
0.0
10.3
—
22.6
—
0
7
(3000093) Morphology [Interpretation] in Blood Narrative
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
6
57
1.07
0.00
2.7
2.5
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood
0
6
0.00
0.00
0.0
1.0
—
18.7
—
0
6
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
16
161
0.97
0.00
14.7
7.8
u/l
21.6
26.1
0.61
16
155
(3007566) Smooth muscle Ab [Titer] in Serum
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3003932) Carbon dioxide [Partial pressure] in Arterial cord blood
0
6
0.00
0.00
0.0
1.0
—
7.1
—
0
6
(42870560) Thyrotropin [Units/volume] in Cord blood
0
8
0.00
0.00
0.0
1.0
—
8.1
—
0
8
(3020891) Body temperature
0
7
0.00
0.00
0.0
9.1
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
0
6
0.00
0.00
0.0
6.8
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_FETAL_BLOOD_LOSS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FETAL_BLOOD_LOSS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_FETAL_BLOOD_LOSS – Fetal blood loss

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data