Feeding problems of newborn

P16_FEEDI_PROBL_NEWBO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P92
  • Cause of death: ICD-10 P92

2 out of 7 registries used, show all original rules.

163

4. Check minimum number of events

None

163

5. Include endpoints

None

163

6. Filter based on genotype QC (FinnGen only)

163

Control definitions (FinnGen only)

Control exclude
P16_OTH_DISORD_ORIGINA_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P9
Name in latin
Perturbationes nutriendi neonati

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11115 5468 5644
Only index persons 3886 2007 1879
Unadjusted period prevalence (%)
Whole population 0.16 0.16 0.16
Only index persons 0.07 0.07 0.07
Median age at first event (years)
Whole population 0.05 0.04 0.04
Only index persons 0.05 0.05 0.04

-FinnGen-

Key figures

All Female Male
Number of individuals 163 107 56
Unadjusted period prevalence (%) 0.03 0.04 0.02
Median age at first event (years) 0.11 0.14 0.05

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
149
Matched controls
1491
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P92.5
ICD-10 Finland
Neonatal difficulty in feeding at breast
+∞
54.6
49
*
P92.9
ICD-10 Finland
Feeding problem of newborn, unspecified
+∞
26.9
25
*
P92.3
ICD-10 Finland
Underfeeding of newborn
+∞
24.7
23
*
P92.1
ICD-10 Finland
Regurgitation and rumination in newborn
+∞
23.6
22
*
P92.0
ICD-10 Finland
Vomiting in newborn
242.5
21.1
21
*
P92.2
ICD-10 Finland
Slow feeding of newborn
+∞
13.8
13
*
MA3AE
NOMESCO Finland
Combined first trimester screening
6.2
8.9
24
45
Z37.0
ICD-10 Finland
Single live birth
5.8
8.3
23
45
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
5.8
7.9
22
43

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3047352) Trisomy 18 risk [Likelihood] in Fetus
29
67
5.05
12.27
1.4
1.4
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
29
67
5.05
12.27
1.4
1.4
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
29
70
4.82
11.63
1.6
1.5
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
29
81
4.14
9.62
1.4
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
29
81
4.14
9.62
1.4
1.5
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
29
81
4.14
9.62
1.4
1.5
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
29
81
4.14
9.62
1.4
1.4
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
29
92
3.62
8.00
1.6
1.5
—
—
—
0
0
(3022621) pH of Urine by Test strip
23
65
3.96
7.45
2.8
1.9
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
15
31
5.23
7.08
2.1
1.7
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
9
6
15.76
5.97
1.8
1.7
—
—
—
0
0
(4211845)
9
6
15.76
5.97
1.8
1.7
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
16
48
3.59
4.74
2.4
2.0
—
—
—
0
0
(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk
9
11
8.58
4.62
1.0
1.0
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
24
95
2.79
4.55
2.2
2.3
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
69
444
1.96
4.15
4.9
4.7
e6/l
0.1
0.3
1.62
45
339
(36304419) Bacteria [Presence] in Urine
69
447
1.94
4.05
4.8
4.7
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
15
49
3.27
3.92
2.1
1.5
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
71
471
1.90
3.83
4.9
5.1
e6/l
26.5
31.2
0.09
49
363
(3044640) Blood type and Crossmatch panel - Blood
57
352
1.95
3.81
2.5
3.7
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
13
40
3.44
3.71
1.1
1.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
80
560
1.84
3.59
5.5
5.8
e6/l
91.3
44.2
0.27
51
375
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
50
305
1.92
3.42
2.4
3.4
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
71
485
1.82
3.40
5.3
5.2
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
32
168
2.13
3.29
1.6
1.5
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
47
284
1.92
3.29
3.2
4.2
e6/l
0.5
0.5
0.04
27
172
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
47
291
1.86
3.03
3.1
4.4
e6/l
1.0
1.5
0.33
27
178
(3019832) Treponema pallidum Ab [Presence] in Serum
47
295
1.83
2.90
1.7
1.8
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
66
480
1.63
2.33
5.0
4.6
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
92
726
1.61
2.33
5.9
8.6
mmol/l
6.2
5.9
0.24
83
671
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
86
668
1.61
2.32
10.9
14.4
mmol/l
1.2
1.2
0.06
81
615
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
40
255
1.75
2.30
1.8
2.1
—
—
—
0
0
(3023323) Follitropin [Units/volume] in Serum or Plasma
22
119
1.98
2.09
1.6
2.2
iu/l
8.4
8.0
0.04
14
71
(3000850) Epithelial cells [#/volume] in Urine
46
315
1.64
2.03
4.4
3.8
e6/l
4.5
7.8
1.92
38
274
(3026782) Osmolality of Urine
45
308
1.64
1.98
4.5
3.6
mosm/kgh2o
588.8
577.9
0.10
37
262
(3018418) pH of Serum or Plasma
38
254
1.65
1.83
5.5
5.1
ph
7.4
7.4
—
8
44
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
9
36
2.59
1.77
1.3
1.3
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
61
460
1.52
1.76
2.0
1.7
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
5
13
3.93
1.73
2.0
1.1
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
41
284
1.59
1.71
1.8
1.7
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
6
19
3.24
1.67
8.7
8.2
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
16
84
2.00
1.66
1.7
1.8
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
32
210
1.65
1.65
1.8
1.9
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
6
20
3.07
1.59
6.7
5.0
e9/l
2.8
2.9
—
6
20
(3011397) Hemoglobin [Presence] in Urine by Test strip
47
345
1.51
1.51
3.5
3.1
—
—
—
0
0
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
50
372
1.50
1.51
7.8
12.0
mmol/l
0.6
1.1
0.97
33
268
(3001019) Free T4 and TSH panel - Serum or Plasma
9
37
2.51
1.50
1.6
1.9
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
31
207
1.61
1.50
1.4
2.0
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
56
428
1.47
1.48
2.8
2.1
—
—
—
0
0
(3009214) Lutropin [Units/volume] in Serum or Plasma
22
135
1.73
1.45
1.6
2.1
u/l
5.8
6.6
0.24
12
76
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
6
22
2.79
1.45
12.0
4.7
%
49.7
49.4
—
6
22
(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method
6
22
2.79
1.45
1.0
1.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
12
60
2.08
1.42
1.8
1.6
—
—
—
0
0
(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma
5
17
3.00
1.37
2.8
2.5
umol/l
72.0
59.5
—
5
17
(40761511) CBC panel - Blood by Automated count
142
1309
1.66
1.35
8.6
8.9
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
20
122
1.73
1.35
2.3
1.8
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
17
99
1.80
1.33
1.7
1.9
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
43
322
1.46
1.24
3.1
2.5
—
—
—
0
0
(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum
6
26
2.36
1.20
2.7
2.7
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
96
831
1.38
1.19
5.0
4.7
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
8
39
2.10
1.17
1.6
1.5
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
15
88
1.78
1.16
1.5
1.3
—
—
—
0
0
(3022313) Gas panel - Capillary blood
44
336
1.42
1.14
8.3
11.6
—
—
—
0
0
(3014133) Dog dander IgE Ab [Units/volume] in Serum
15
89
1.75
1.12
1.1
1.1
u/ml
5.4
6.5
—
8
58
(3009261) Glucose [Presence] in Urine by Test strip
69
572
1.36
1.10
4.8
3.6
estimate
0.0
0.0
0.00
11
95
(3021601) Nitrite [Presence] in Urine by Test strip
68
565
1.35
1.06
6.3
5.3
estimate
0.0
0.0
0.00
11
95
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
9
46
2.01
1.05
1.7
1.4
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
68
566
1.35
1.05
4.5
3.5
estimate
0.0
0.0
0.00
11
89
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
51
406
1.37
1.04
9.7
15.5
mmol/l
24.6
24.7
0.10
51
406
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
55
445
1.36
1.01
2.0
2.0
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
9
49
1.88
1.00
1.3
1.6
—
—
—
0
0
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
22
150
1.54
0.99
2.3
2.8
u/l
12003.7
3761.8
—
9
56
(3022145) Colonoscopy Study observation
10
54
1.91
0.99
2.1
1.6
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
19
126
1.57
0.96
1.9
2.0
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
19
126
1.57
0.96
1.9
2.1
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
32
0.00
0.96
0.0
1.2
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
127
1171
1.38
0.93
14.5
14.8
mmol/l
4.0
3.9
0.15
121
1127
(3019550) Sodium [Moles/volume] in Serum or Plasma
127
1172
1.38
0.91
14.6
14.9
mmol/l
139.3
139.3
0.01
122
1138
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
28
205
1.44
0.91
1.1
1.1
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
18
120
1.56
0.90
1.7
1.7
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
6
31
1.97
0.85
2.2
1.4
—
—
—
0
0
(3023430) Cat dander IgE Ab [Units/volume] in Serum
13
81
1.66
0.84
1.1
1.2
u/ml
36.8
9.2
—
7
55
(3014148) Varicella zoster virus Ab [Titer] in Serum
8
46
1.78
0.84
1.3
1.3
—
—
—
0
0
(21494815) CD4 cells/100 lymphocytes in Specimen
8
48
1.70
0.80
3.0
3.5
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
42
339
1.32
0.77
2.5
1.7
—
—
—
0
0
(3015736) pH of Urine
54
452
1.29
0.77
3.4
3.3
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
9
54
1.71
0.76
1.0
1.2
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
45
368
1.31
0.76
6.3
10.4
mmol/l
1.5
1.0
0.82
36
282
(3009542) Hematocrit [Volume Fraction] of Blood
148
1414
1.51
0.75
13.3
16.2
%
37.6
38.5
1.20
139
1311
(3002523) Influenza virus A Ag [Presence] in Specimen
9
55
1.67
0.75
1.0
1.2
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
44
360
1.30
0.74
4.4
3.3
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
5
26
1.95
0.71
1.8
2.9
mmol/l
1.7
1.6
—
5
26
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
31
243
1.34
0.70
1.5
1.6
pmol/l
89.6
95.3
0.27
17
124
(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
5
27
1.88
0.69
1.0
1.1
—
1.5
—
0
17
(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum
12
79
1.56
0.64
1.1
1.1
u/ml
0.0
0.5
—
6
46
(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum
5
29
1.75
0.64
1.0
1.0
—
—
—
0
0
(3008295) Osmolality of Serum or Plasma
5
29
1.75
0.64
2.2
1.7
mosm/kgh2o
300.4
294.0
—
5
21
(3023520) Reticulocytes [#/volume] in Blood
19
139
1.42
0.64
2.9
4.7
e9/l
96.8
60.1
0.60
11
92
(3023368) Bacteria identified in Blood by Culture
28
220
1.33
0.62
6.6
4.4
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
8
51
1.60
0.61
1.1
1.2
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
8
52
1.57
0.60
3.0
3.3
—
—
—
0
0
(1175426) CD3 cells/100 lymphocytes in Blood
8
52
1.57
0.60
3.0
3.3
%
72.4
63.8
—
8
52
(3041096) Erythrocytes [Presence] in Urine by Automated
32
258
1.30
0.60
4.4
3.4
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
21
160
1.36
0.57
2.1
2.0
—
—
—
0
0
(3002256) Pathology report gross observation
14
99
1.45
0.56
1.1
1.2
—
—
—
0
0
(3027231) Wheat IgE Ab [Units/volume] in Serum
6
37
1.64
0.56
1.7
1.3
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
6
37
1.64
0.56
1.3
13.1
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
9
59
1.56
0.56
1.4
1.2
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
9
62
1.48
0.54
2.7
2.1
—
—
—
0
0
(3034274) Bile acid [Moles/volume] in Serum --fasting
12
84
1.46
0.51
1.9
5.1
umol/l
4.5
14.2
2.18
12
71
(3027945) Reticulocytes/100 erythrocytes in Blood
26
211
1.28
0.47
3.7
6.8
%
1.4
1.3
0.14
26
201
(3021879) Hepatitis B virus core Ab [Presence] in Serum
14
103
1.39
0.47
2.0
1.4
—
—
—
0
0
(42870560) Thyrotropin [Units/volume] in Cord blood
13
95
1.40
0.45
1.0
1.0
mu/l
10.7
8.6
0.50
13
89
(3005719) IgG [Mass/volume] in Serum or Plasma
21
167
1.30
0.44
3.3
4.1
g/l
8.3
8.3
0.03
21
161
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
139
1338
1.26
0.44
13.3
11.9
mg/l
25.2
22.3
0.48
99
927
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
42
364
1.21
0.43
3.4
2.6
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
14
105
1.36
0.42
1.7
2.1
—
—
—
0
0
(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma
5
32
1.58
0.42
1.0
1.2
—
—
—
0
0
(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay
5
32
1.58
0.42
1.0
1.2
%
80.8
72.0
—
5
32
(3007164) IgA [Mass/volume] in Serum or Plasma
69
628
1.17
0.41
1.9
1.6
g/l
1.4
1.5
0.30
37
299
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3019060) Gas panel - Arterial blood
0
15
0.00
0.41
0.0
3.4
—
—
—
0
0
(3041806) Other cells [#/volume] in Blood by Manual count
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
(3004409) Coagulation factor X activity actual/normal in Platelet poor plasma by Coagulation assay
0
17
0.00
0.41
0.0
1.2
—
87.4
—
0
11
(3005353) Prothrombin activity actual/normal in Platelet poor plasma by Coagulation assay
0
17
0.00
0.41
0.0
1.0
—
90.1
—
0
11
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
5
34
1.49
0.40
6.2
5.1
umol/l
26.4
26.6
—
5
34
(3003458) Phosphate [Moles/volume] in Serum or Plasma
39
338
1.20
0.40
12.2
12.3
mmol/l
1.4
1.4
0.03
39
324
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
10
71
1.44
0.40
1.1
1.2
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
8
61
1.33
0.40
7.5
2.5
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
18
143
1.29
0.39
1.7
1.7
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
9
67
1.36
0.39
1.3
1.2
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
9
69
1.32
0.38
1.4
1.6
g/l
1.2
1.2
—
9
64
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
9
70
1.30
0.37
2.0
2.0
—
—
—
0
0
(3013512) EKG study
9
122
0.72
0.37
2.3
3.0
—
—
—
0
0
(3006184) Hemoglobin [Mass/volume] in Capillary blood
6
44
1.38
0.35
1.3
2.6
g/l
121.2
127.9
—
6
37
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
73
679
1.14
0.31
7.4
5.5
u/l
139.5
134.5
0.16
68
634
(3010813) Leukocytes [#/volume] in Blood
155
1522
1.37
0.30
18.2
17.6
e9/l
7.4
7.1
1.01
150
1446
(3026361) Erythrocytes [#/volume] in Blood
155
1521
1.39
0.30
18.2
17.6
e12/l
4.5
4.5
0.54
148
1444
(3006245) CD3-CD19+ cells/100 cells in Blood
7
56
1.26
0.30
2.0
3.9
%
14.9
16.3
—
7
56
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
14
172
0.80
0.29
1.9
1.3
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
9
120
0.74
0.28
1.3
1.3
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
15
122
1.25
0.28
1.3
1.5
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
21
245
0.84
0.27
5.0
4.5
inr
1.0
1.1
—
7
66
(21494755) Public health laboratory ask at order entry panel
9
72
1.26
0.26
1.0
1.2
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
9
73
1.25
0.26
1.1
1.1
—
—
—
0
0
(4035726)
10
78
1.30
0.25
2.8
1.8
—
—
—
0
0
(1616796) Gas panel - Central venous blood
5
37
1.36
0.24
9.8
5.1
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
11
88
1.27
0.23
9.4
3.8
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
5
39
1.29
0.23
1.8
1.8
—
—
—
0
0
(3000991) Gas panel - Venous blood
36
326
1.13
0.22
9.3
13.0
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
18
154
1.19
0.22
1.7
1.6
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
18
154
1.19
0.22
1.9
1.6
—
—
—
0
0
(3001684) Respiratory syncytial virus Ag [Presence] in Specimen
5
41
1.23
0.22
1.0
1.3
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
66
621
1.11
0.22
13.5
6.8
ml/min/173m2
113.3
111.3
0.26
44
395
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
68
641
1.10
0.22
2.0
1.8
u/ml
4.3
4.6
0.05
11
92
(3021578) Parainfluenza virus 2 Ag [Presence] in Specimen
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(4094501)
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3010464) Parainfluenza virus 1 Ag [Presence] in Specimen
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3005880) Parainfluenza virus 3 Ag [Presence] in Specimen
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(42869858) Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(3036071) Salmonella sp Ab [Titer] in Serum
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3012320) Pathologist interpretation of Cerebral spinal fluid tests
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3028772) Osteocalcin [Mass/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
(3014373) Corynebacterium diphtheriae Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
10
80
1.27
0.21
1.8
2.0
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
18
155
1.18
0.21
1.7
1.6
—
—
—
0
0
(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood
6
48
1.26
0.20
1.7
3.2
%
21.8
23.1
—
6
48
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
6
48
1.26
0.20
1.2
2.3
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
(3016273) Islet cell 512 Ab [Units/volume] in Serum
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
6
50
1.21
0.20
2.2
2.0
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
16
137
1.19
0.19
2.0
1.4
%
1.3
1.4
0.20
16
124
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
18
205
0.86
0.18
1.3
2.0
mmol/l
1.1
1.2
0.34
18
188
(3012494) Peanut IgE Ab [Units/volume] in Serum
7
59
1.19
0.18
1.3
1.3
u/ml
2.2
55.7
—
7
46
(3021589) Normoblasts [#/volume] in Blood
88
846
1.09
0.17
9.4
11.8
e9/l
0.0
0.0
0.00
63
648
(3042936) Bacteria identified in Isolate by Culture
15
130
1.17
0.16
2.0
2.2
—
—
—
0
0
(3016244) Insulin [Units/volume] in Serum or Plasma
8
72
1.12
0.16
2.4
3.3
mu/l
18.7
14.7
—
8
66
(3021706) Oxygen [Partial pressure] in Arterial cord blood
9
80
1.13
0.15
1.0
1.0
kpa
3.7
3.4
—
9
72
(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood
9
80
1.13
0.15
1.0
1.0
mmol/l
19.6
19.7
—
9
80
(3003932) Carbon dioxide [Partial pressure] in Arterial cord blood
9
81
1.12
0.15
1.0
1.0
kpa
6.4
7.1
—
9
73
(3006598) pH of Arterial cord blood
9
81
1.12
0.15
1.0
1.0
—
—
—
0
0
(3010726) Horse dander IgE Ab [Units/volume] in Serum
17
150
1.15
0.15
1.2
1.2
u/ml
0.6
4.4
—
7
54
(3028026) IgM [Mass/volume] in Serum or Plasma
15
131
1.16
0.15
2.3
2.1
g/l
1.0
1.0
0.06
15
123
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
7
86
0.81
0.15
1.1
1.1
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
71
681
1.08
0.14
7.1
10.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
29
267
1.10
0.14
5.3
3.7
estimate
0.0
0.0
0.00
11
89
(3019198) Lymphocytes [#/volume] in Blood
92
893
1.07
0.13
7.6
9.7
e9/l
2.6
2.5
0.55
78
765
(3027944) Amphetamines [Presence] in Urine
17
152
1.13
0.13
1.9
1.6
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
95
924
1.07
0.12
8.4
11.4
e9/l
3.6
3.4
0.23
75
776
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
10
116
0.85
0.12
1.1
1.1
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
5
44
1.14
0.10
2.4
2.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
28
262
1.08
0.10
12.2
5.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
10
114
0.87
0.10
1.6
1.5
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
89
868
1.06
0.09
7.8
9.9
e9/l
0.0
0.0
0.07
70
719
(3014007) Fractional oxyhemoglobin in Arterial blood
5
47
1.07
0.09
17.4
26.4
%
95.6
95.0
—
5
47
(3045462) Protein/Creatinine [Ratio] in Urine
5
48
1.04
0.09
11.8
8.9
g/mol
30.2
1161.1
—
5
42
(3014765) Yersinia sp identified in Stool by Organism specific culture
5
48
1.04
0.09
1.2
1.3
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
11
97
1.14
0.09
1.1
1.4
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
25
267
0.92
0.09
3.0
2.9
kg/l
1.0
1.0
0.13
11
60
(3001604) Monocytes [#/volume] in Blood
89
869
1.05
0.09
7.7
9.8
e9/l
0.6
0.6
0.18
70
720
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
6
57
1.05
0.08
1.0
1.2
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
6
58
1.04
0.08
2.2
2.2
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
5
61
0.81
0.08
1.2
1.5
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
5
61
0.81
0.08
1.2
1.5
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
74
721
1.05
0.08
2.3
2.1
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
8
74
1.09
0.07
1.3
1.1
—
—
—
0
0
(3000492) Spirometry study
8
78
1.03
0.07
1.0
1.5
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
9
83
1.09
0.07
1.8
1.9
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
9
83
1.09
0.07
3.0
3.0
pmol/l
5.1
5.2
—
9
73
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
14
128
1.10
0.07
1.9
8.5
g/l
3.5
2.8
0.47
14
123
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
8
93
0.85
0.07
3.4
2.2
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
8
94
0.84
0.07
3.4
2.2
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
90
883
1.04
0.06
8.2
10.8
e9/l
0.2
0.2
0.43
74
755
(3008401) Mugwort IgE Ab [Units/volume] in Serum
16
149
1.08
0.05
1.2
1.2
u/ml
0.1
1.0
1.25
11
122
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
12
110
1.10
0.05
2.0
2.2
—
—
—
0
0
(3044889) 12 lead EKG panel
47
483
0.96
0.04
3.0
2.2
—
—
—
0
0
(40758558) Short blood count panel - Blood
56
547
1.04
0.04
5.0
10.0
—
—
—
0
0
(3003888) Timothy IgE Ab [Units/volume] in Serum
16
150
1.07
0.04
1.2
1.2
u/ml
0.4
6.4
4.41
11
126
(36660697) Celiac disease serology panel - Serum
29
279
1.05
0.04
1.4
1.2
—
—
—
0
0
(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma
10
109
0.91
0.04
5.3
4.7
nmol/l
27.1
23.0
—
10
109
(3050129) First trimester maternal screen panel - Serum or Plasma
12
111
1.09
0.04
1.0
1.4
—
—
—
0
0
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
17
161
1.06
0.03
1.2
1.3
u/ml
0.3
3.0
1.72
12
116
(3017143) Hepatitis C virus Ab [Presence] in Serum
19
199
0.95
0.03
2.5
1.5
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
10
108
0.92
0.03
1.2
1.3
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
15
143
1.05
0.01
2.0
10.4
%
97.1
90.3
0.71
15
143
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
141
1403
1.04
0.01
4.6
4.1
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
14
136
1.03
0.00
10.4
16.7
mmol/l
1.5
1.4
0.02
14
120
(3048929) Epstein Barr virus Ab [Presence] in Serum
19
189
1.01
0.00
1.8
1.9
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
22
219
1.01
0.00
1.5
5.8
mg/l
1.4
1.5
0.10
16
153
(3017732) Neutrophils [#/volume] in Blood
10
97
1.03
0.00
1.5
1.8
e9/l
3.6
4.2
—
10
91
(3007853) Bacteria identified in Skin by Aerobe culture
20
195
1.03
0.00
2.1
2.1
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
34
338
1.01
0.00
3.3
2.4
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
14
142
0.98
0.00
2.4
2.8
ng/l
8.8
12.5
—
9
47
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
6
65
0.92
0.00
14.7
19.7
mmol/l
1.7
0.6
—
6
55
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(43055222) Platelet function.collagen + Adenosine diphosphate induced and EPINEPHrine induced panel - Blood
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
3.1
—
3.7
—
0
8
(42868415) European tick borne encephalitis virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3022192) Triglyceride [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032868) Hemoglobin electrophoresis panel in Blood
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3045209) Lutropin/Follitropin [Ratio] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40757578) FLT3 gene targeted mutation analysis in Bone marrow by Molecular genetics method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3017461) Flecainide [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
6.2
—
0.5
—
0
6
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3036669) Protein S actual/normal in Platelet poor plasma by Coagulation assay
0
7
0.00
0.00
0.0
1.0
—
87.3
—
0
7
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
5
50
1.00
0.00
1.2
1.2
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3013931) Oligosaccharides [Presence] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043257) Herpes virus 6 IgG Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002222) Hepatitis E virus IgM Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026179) Normetanephrine [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.1
—
0.7
—
0
9
(3032567) Hepatitis B virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3034368) Herpes virus 6 IgM Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
12
120
1.00
0.00
1.9
7.2
%
167.4
163.9
0.04
12
120
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
5
52
0.96
0.00
17.4
23.5
mmol/l
24.6
24.5
—
5
52
(3009871) Measles virus Ab [Titer] in Serum
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
6
61
0.98
0.00
2.2
2.4
—
—
—
0
0
(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting
5
55
0.91
0.00
4.6
2.2
nmol/l
0.2
0.5
—
5
46
(3008536) Aspergillus sp Ab [Presence] in Serum
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
5
59
0.84
0.00
1.4
1.4
—
—
—
0
0
(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
82.4
—
0
5
(4024509)
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035401) Herpes virus 6 DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3034426) Prothrombin time (PT)
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(21491868) Cryoglobulin [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3006922) Hepatitis E virus Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3017315) Amylase [Enzymatic activity/volume] in Urine
0
6
0.00
0.00
0.0
1.7
—
132.8
—
0
6

Mortality – FinRegistry

Association

Association between endpoint P16_FEEDI_PROBL_NEWBO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FEEDI_PROBL_NEWBO.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_FEEDI_PROBL_NEWBO – Feeding problems of newborn

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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