This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD

Congenital pneumonia

Endpoint Browser

P16_CONGN_PNEUMON

No definition available.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P23 Cause of death: ICD-10 — P23 2 out of 7 registries used, show all original rules.	15
4. Check minimum number of events None	15
5. Include endpoints None	15
6. Filter based on genotype QC (FinnGen only)	15

Control definitions (FinnGen only)

Control exclude: P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P2
Name in latin: Pneumonia congenita

NAME	P16_CONGN_PNEUMON
CONTROL_EXCLUDE	P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P23
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P23
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Congenital pneumonia based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

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FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1698	671	1027
Only index persons	815	297	518
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.03
Only index persons	0.02	0.01	0.02
Median age at first event (years)
Whole population	-	0.00	0.00
Only index persons	0.00	0.00	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	15	9	6
Unadjusted period prevalence (%)	0.00	0.00	0.00
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(3023368) Bacteria identified in Blood by Culture

4.53

1.89

2.8

5.0

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

3.64

1.55

6.2

2.7

u/l

221.3

563.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

2.35

0.91

2.5

1.8

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.88

0.0

2.4

—

(3032080) INR in Blood by Coagulation assay

2.08

0.71

5.6

3.8

—

1.1

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

115

0.61

0.44

3.8

3.4

—

(3015736) pH of Urine

1.83

0.44

4.5

3.3

—

(3013512) EKG study

0.00

0.44

0.0

3.3

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.43

0.0

1.1

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.43

0.0

1.3

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

1.80

0.41

12.3

10.0

mmol/l

1.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.60

0.39

2.6

1.8

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

1.79

0.38

12.7

6.1

e9/l

4.6

3.9

—

(3006315) Basophils [#/volume] in Blood

1.75

0.38

13.8

4.7

e9/l

0.0

—

(3013115) Eosinophils [#/volume] in Blood

1.71

0.38

13.9

4.9

e9/l

0.1

0.2

—

(3001604) Monocytes [#/volume] in Blood

1.66

0.37

13.7

4.6

e9/l

0.6

—

(42870588) Differential panel, method unspecified - Blood

1.41

0.24

4.5

—

(3019198) Lymphocytes [#/volume] in Blood

1.50

0.23

14.0

4.5

e9/l

1.6

2.0

—

(3037467) Urinalysis macro (dipstick) panel - Urine

0.70

0.23

2.2

3.3

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

0.00

0.22

0.0

1.4

—

399.5

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

0.00

0.22

0.0

1.9

—

1.2

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.22

0.0

1.3

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.22

0.0

1.0

—

(40761536) Microorganisms panel - Urine sediment

0.00

0.21

0.0

1.9

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

2.8

—

(3006504) Eosinophils/100 leukocytes in Blood

1.30

0.10

15.0

4.6

2.2

3.1

—

(4198724)

0.00

0.0

1.5

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.4

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

1.1

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

0.0

3.8

—

38.3

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.2

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

0.90

0.00

6.4

2.4

pmol/l

15.3

14.3

—

(3002256) Pathology report gross observation

0.00

0.0

1.5

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

0.00

0.0

14.0

—

120.8

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.0

2.5

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.8

—

(3022621) pH of Urine by Test strip

0.00

0.0

1.3

—

(3044889) 12 lead EKG panel

0.92

0.00

1.8

2.0

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.0

1.0

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

2.0

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

0.00

0.0

2.1

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.0

1.2

—

(3000330) Specific gravity of Urine by Test strip

0.00

0.0

1.2

—

(3021601) Nitrite [Presence] in Urine by Test strip

1.12

0.00

5.7

4.0

—

0.0

—

(3035350) Ketones [Presence] in Urine by Test strip

1.12

0.00

4.5

3.0

—

0.0

—

(3009261) Glucose [Presence] in Urine by Test strip

1.12

0.00

4.5

3.0

—

0.0

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.7

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.6

—

(3008898) HLA-B27 [Presence]

0.00

0.0

1.1

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_CONGN_PNEUMON and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_CONGN_PNEUMON.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_CONGN_PNEUMON – Congenital pneumonia

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

Extremity

rg [CI]

Extremity

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Congenital pneumonia

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints