Chronic respiratory disease originating in the perinatal period

P16_CHRONIC_RESPI_DISEA_ORIGINA_PERINA_PERIOD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P27
  • Cause of death: ICD-10 P27

2 out of 7 registries used, show all original rules.

81

4. Check minimum number of events

None

81

5. Include endpoints

None

81

6. Filter based on genotype QC (FinnGen only)

81

Control definitions (FinnGen only)

Control exclude
P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P2
Name in latin
Morbus respiratorius chronicus origine perinatalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2666 1099 1567
Only index persons 1532 618 914
Unadjusted period prevalence (%)
Whole population 0.04 0.03 0.04
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population - 0.00 0.00
Only index persons 0.03 0.00 0.04

-FinnGen-

Key figures

All Female Male
Number of individuals 81 42 39
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 0.04 0.04 0.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
67
Matched controls
671
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
7837.3
84.5
63
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
124.3
46.8
48
13
P07.2
ICD-10 Finland
Extreme immaturity
+∞
38.2
33
*
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
+∞
30.6
27
*
602
Kela drug reimbursment
Children's severe malnutrition
30.9
23.6
32
19
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
16.5
23.2
47
83
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
22.1
20
*
P29.30
ICD-10 Finland
Delayed closure of the ductus arteriosus
+∞
18.6
17
*
J45.1
ICD-10 Finland
Nonallergic asthma
12.7
18.0
37
59
WX722
NOMESCO Finland
PEEP
49.8
18.0
21
6
P07.3
ICD-10 Finland
Other preterm infants
22.6
16.5
24
16
R03BA02
ATC
budesonide; inhalant
10.1
15.4
36
69
F82
ICD-10 Finland
Specific developmental disorder of motor function
22.8
14.7
21
13
P07.01
ICD-10 Finland
Extremely low birth weight 500-749 g
+∞
14.0
13
*
FDE00
NOMESCO Finland
Closure of patent ductus arteriosus
+∞
14.0
13
*
WX730
NOMESCO Finland
Conventional respirator
63.2
13.5
15
*
P07.02
ICD-10 Finland
Extremely low birth weight 750-999 g
+∞
11.8
11
*
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
129.4
10.8
11
*
XG413
NOMESCO Finland
Spirometry with oscillometry
15.8
10.6
17
14
6BB16
NOMESCO Finland
NA
47.8
10.3
12
*
Z3229
NOMESCO Finland
Other healthcare associate professional
8.0
10.3
25
46
R4110
NOMESCO Finland
Physiotherapy
5.8
10.3
39
130
RK310
NOMESCO Finland
NA
+∞
9.6
9
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
10.1
9.5
19
25
J45.9
ICD-10 Finland
Asthma, unspecified
6.2
9.5
29
73
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
15.7
9.4
15
12
WX408
NOMESCO Finland
General anesthesy, balanced
5.2
9.3
42
163
P05.1
ICD-10 Finland
Small for gestational age
28.7
9.3
12
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
6.7
9.3
26
58
R03AC02
ATC
salbutamol; inhalant
6.0
9.1
55
289
WX704
NOMESCO Finland
Intubation
19.7
9.0
13
8
R03AK06
ATC
salmeterol and fluticasone; inhalant
7.6
8.6
21
38
ZXD05
NOMESCO Finland
Urgent procedure
5.2
8.4
31
95
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.0
8.3
25
60
WX725
NOMESCO Finland
Noninvasive ventilation
25.8
8.3
11
5
ZX114
NOMESCO Finland
Intramuscular
13.2
8.3
14
13
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.2
8.1
29
85
Z2446
NOMESCO Finland
Social worker
5.0
8.0
31
99
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
5.3
7.7
26
71
R03BA05
ATC
fluticasone; inhalant
4.5
7.7
36
136
RK320
NOMESCO Finland
NA
89.6
7.6
8
*
RK520
NOMESCO Finland
NA
89.6
7.6
8
*
XA800
NOMESCO Finland
Neuropsychological investigation
6.9
7.5
19
36
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
6.2
7.5
21
46
WX732
NOMESCO Finland
High frequency respirator
+∞
7.4
7
*
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
+∞
7.4
7
*
Z3226
NOMESCO Finland
Physiotherapist
4.4
7.4
35
133
ZX108
NOMESCO Finland
Inhalation
16.1
7.2
11
8
Z3231
NOMESCO Finland
Registered nurse
4.1
7.1
43
202
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
19.2
7.0
10
6
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
19.2
7.0
10
6
Z2221
NOMESCO Finland
Medical doctor
4.1
6.8
33
127
ZXD10
NOMESCO Finland
Scheduled procedure
4.0
6.8
40
180
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
6.5
6.6
17
33
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
76.9
6.5
7
*
ZXE00
NOMESCO Finland
One hour or less
3.9
6.5
41
192
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
9.2
6.5
13
17
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
6.3
6.4
17
34
WX882
NOMESCO Finland
High dependency care
5.0
6.4
22
60
RK312
NOMESCO Finland
NA
29.8
6.4
8
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.8
6.4
41
198
P29.31
ICD-10 Finland
Persistent fetal circulation
+∞
6.3
6
*
RK290
NOMESCO Finland
NA
+∞
6.3
6
*
ZXE10
NOMESCO Finland
More than one and less than three hours
3.9
6.3
34
140
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
11.7
6.3
11
11
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
7.1
6.3
15
26
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
7.7
6.3
14
22
Z2445
NOMESCO Finland
Psychologist
4.8
6.2
22
62
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.9
6.2
21
57
UGC02
NOMESCO Finland
Rigid bronchoscopy
17.0
6.1
9
6

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
14
28
5.81
6.95
1.6
1.8
—
—
—
0
0
(44806118)
14
32
5.05
5.99
1.7
2.0
—
—
—
0
0
(44790047)
14
32
5.05
5.99
1.7
2.0
—
—
—
0
0
(44790049)
14
32
5.05
5.99
1.7
2.0
—
—
—
0
0
(44790048)
14
32
5.05
5.99
1.7
2.0
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
23
78
3.70
5.96
2.6
2.0
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
24
84
3.62
5.93
2.1
1.3
pmol/l
98.5
97.4
0.04
11
44
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
15
38
4.59
5.69
1.7
1.9
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
15
38
4.59
5.69
1.7
2.3
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
23
81
3.55
5.61
2.7
2.0
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
13
33
4.48
4.89
1.8
1.8
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
12
29
4.66
4.78
1.8
1.9
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
11
25
4.91
4.69
1.8
1.4
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
11
25
4.91
4.69
1.8
1.4
—
—
—
0
0
(4010399)
12
30
4.50
4.59
1.9
1.3
—
—
—
0
0
(3000991) Gas panel - Venous blood
32
159
2.66
4.17
6.0
14.0
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
23
97
2.90
4.08
2.7
2.1
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
51
321
2.57
4.02
5.8
13.7
—
—
—
0
0
(3000492) Spirometry study
12
34
3.95
3.90
1.7
1.4
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
59
413
2.55
3.49
7.9
11.9
e9/l
2.7
2.6
0.29
53
338
(3006315) Basophils [#/volume] in Blood
58
403
2.52
3.49
8.0
12.0
e9/l
0.0
0.0
0.41
50
318
(3019069) Monocytes/100 leukocytes in Blood
57
398
2.43
3.31
6.5
12.3
%
8.6
8.2
0.62
52
386
(40758558) Short blood count panel - Blood
40
241
2.29
3.28
6.5
10.0
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
60
430
2.50
3.26
9.1
14.5
e9/l
3.4
3.6
0.18
51
346
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
31
170
2.32
3.14
32.5
12.2
mmol/l
1.2
1.0
0.24
26
128
(3001604) Monocytes [#/volume] in Blood
57
405
2.35
3.08
8.1
11.9
e9/l
0.6
0.6
0.67
49
320
(3021589) Normoblasts [#/volume] in Blood
56
396
2.32
3.04
9.6
14.7
e9/l
0.0
0.0
0.50
48
286
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
30
165
2.29
3.00
32.9
10.6
mmol/l
24.3
24.0
0.32
30
165
(3024891) Influenza virus A+B Ag [Presence] in Specimen
11
37
3.27
2.79
1.5
1.3
—
—
—
0
0
(3022313) Gas panel - Capillary blood
28
158
2.17
2.58
34.6
11.6
—
—
—
0
0
(3020393) Adenovirus Ag [Presence] in Stool
8
22
3.90
2.42
1.6
2.0
—
—
—
0
0
(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay
5
8
6.54
2.39
1.0
1.3
%
95.8
111.5
—
5
8
(3035320) C reactive protein [Mass/volume] in Body fluid
6
13
4.86
2.30
2.0
2.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
33
208
1.98
2.22
2.7
4.1
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
24
139
2.02
2.02
2.0
3.5
e6/l
0.8
0.6
0.17
13
74
(3022670) pH of Venous cord blood
5
11
4.74
1.96
1.0
1.0
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
5
11
4.74
1.96
1.0
1.2
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
32
208
1.88
1.92
2.8
4.1
e6/l
0.1
0.4
0.65
20
145
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
8
28
3.04
1.91
2.1
3.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
10
40
2.70
1.90
2.7
1.6
—
—
—
0
0
(3044889) 12 lead EKG panel
32
210
1.85
1.86
3.5
2.2
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
39
274
1.80
1.81
3.9
3.0
mmol/mol
35.3
35.9
0.19
34
256
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
31
203
1.84
1.80
35.2
18.2
mmol/l
25.1
24.7
0.32
31
203
(3002582) Erythrocytes [#/volume] in Urine
33
222
1.81
1.75
2.7
4.3
e6/l
12.1
34.2
1.02
19
161
(3023103) Potassium [Moles/volume] in Serum or Plasma
66
551
2.04
1.69
27.3
16.8
mmol/l
4.0
3.9
0.84
66
530
(3025941) Bacteria identified in Stool by Culture
7
25
2.95
1.68
1.3
1.1
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
20
116
1.95
1.66
5.0
4.9
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
36
253
1.75
1.63
3.6
5.3
e6/l
11.5
27.7
1.04
20
161
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
23
141
1.87
1.62
2.0
3.4
e6/l
2.8
1.7
0.37
12
76
(3019550) Sodium [Moles/volume] in Serum or Plasma
66
554
2.00
1.62
27.3
16.9
mmol/l
139.0
139.2
0.41
66
537
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
63
521
1.91
1.62
5.1
3.5
mu/l
2.0
2.0
0.18
58
487
(3023709) Somatotropin [Mass/volume] in Serum or Plasma
6
20
3.14
1.60
6.2
5.9
ug/l
2.6
2.7
—
6
20
(3009466) Valproate [Moles/volume] in Serum or Plasma
5
15
3.46
1.54
2.4
4.2
umol/l
349.4
414.0
—
5
15
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
5
15
3.46
1.54
4.2
3.4
umol/l
22.0
20.5
—
5
15
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
6
21
2.98
1.53
1.7
1.6
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
22
137
1.82
1.47
1.2
1.2
—
—
—
0
0
(3026285) Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma
5
16
3.24
1.45
1.0
1.0
g/l
1.4
1.3
—
5
16
(3018133) Calcium [Moles/volume] in Urine
5
17
3.05
1.37
4.0
4.4
mmol/l
2.2
2.4
—
5
17
(40761511) CBC panel - Blood by Automated count
70
611
2.03
1.36
16.4
8.9
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
33
236
1.66
1.35
3.4
4.3
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
18
110
1.81
1.27
2.9
7.4
mg/l
2.1
2.1
0.02
13
86
(3014765) Yersinia sp identified in Stool by Organism specific culture
6
25
2.50
1.26
1.0
1.0
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
46
363
1.60
1.25
3.7
4.1
—
24.4
—
0
7
(3009542) Hematocrit [Volume Fraction] of Blood
74
667
2.20
1.24
23.7
18.7
%
39.7
38.6
1.26
68
609
(42529406) Shigella sp [Presence] in Stool by Culture
6
26
2.40
1.20
1.0
1.0
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
11
58
2.03
1.17
1.9
1.5
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
41
320
1.56
1.13
1.9
2.0
—
—
—
0
0
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
14
82
1.84
1.12
12.3
22.0
mg/l
1.1
1.0
0.38
14
82
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
8
41
2.04
1.11
1.8
1.7
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
25
174
1.62
1.11
4.0
4.4
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
71
635
1.91
1.09
20.6
13.4
mg/l
18.7
22.8
0.82
54
452
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
12
68
1.89
1.06
1.8
2.9
ng/l
8.5
21.1
—
6
29
(3001684) Respiratory syncytial virus Ag [Presence] in Specimen
5
22
2.34
1.04
1.0
1.3
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
11
61
1.92
1.03
1.7
1.5
%
1.4
1.3
0.15
11
56
(4035726)
7
35
2.08
1.02
1.6
2.0
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
7
35
2.08
1.02
1.4
2.0
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
29
0.00
1.00
0.0
1.0
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
36
280
1.50
0.98
10.3
7.0
ml/min/173m2
110.5
113.2
0.28
28
183
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
22
154
1.58
0.95
3.7
3.9
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
46
378
1.49
0.94
3.7
4.5
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
6
28
2.22
0.93
1.5
1.7
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
6
30
2.07
0.88
1.7
1.5
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
6
30
2.07
0.88
1.0
2.5
—
—
—
0
0
(3022145) Colonoscopy Study observation
6
31
2.00
0.86
1.0
1.5
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
8
48
1.73
0.81
1.3
1.5
—
—
—
0
0
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
0
26
0.00
0.80
0.0
1.4
—
0.0
—
0
6
(3037522) Nuclear Ab [Titer] in Serum
12
75
1.70
0.79
1.2
1.6
—
392.7
—
0
11
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
10
59
1.78
0.79
1.0
1.9
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
5
23
2.24
0.77
1.0
1.0
—
—
—
0
0
(3013512) EKG study
9
56
1.67
0.75
3.2
2.8
—
—
—
0
0
(3015736) pH of Urine
27
213
1.39
0.64
2.9
3.8
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
11
72
1.60
0.62
2.3
2.1
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
10
64
1.63
0.61
3.3
8.3
%
129.2
160.2
—
10
64
(3013707) Erythrocyte sedimentation rate by Westergren method
46
398
1.35
0.61
3.8
4.4
mm/h
7.1
7.7
0.21
41
368
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
0
22
0.00
0.60
0.0
31.5
—
0.3
—
0
16
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
6
34
1.81
0.60
8.2
27.7
mmol/l
22.7
24.4
—
6
34
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
15
199
0.69
0.57
2.7
2.0
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
6
40
1.53
0.52
2.5
27.6
%
1.1
1.2
—
6
40
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
15
110
1.44
0.52
1.5
2.0
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
35
297
1.30
0.50
4.1
2.7
mmol/l
1.2
1.1
0.08
35
282
(3026782) Osmolality of Urine
17
129
1.39
0.50
2.8
3.1
mosm/kgh2o
605.5
567.1
0.22
12
105
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
5
84
0.57
0.48
1.2
1.3
u/ml
0.1
3.2
—
5
61
(3013139) Helicobacter pylori Ag [Presence] in Stool
5
32
1.59
0.43
1.0
1.0
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
17
133
1.34
0.42
2.6
3.7
e6/l
8.8
8.6
0.01
12
113
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
31
267
1.25
0.38
3.4
3.9
estimate
0.0
0.0
—
5
45
(3003888) Timothy IgE Ab [Units/volume] in Serum
5
78
0.61
0.37
1.2
1.2
u/ml
9.1
6.0
—
5
65
(3008401) Mugwort IgE Ab [Units/volume] in Serum
5
78
0.61
0.37
1.2
1.2
u/ml
0.2
1.1
—
5
63
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
35
307
1.24
0.36
1.4
1.9
u/ml
1.7
5.4
—
5
42
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
12
91
1.37
0.35
1.4
1.9
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
6
46
1.32
0.33
4.2
4.2
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
14
111
1.31
0.31
1.1
1.6
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
7
54
1.32
0.31
1.1
1.6
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
7
55
1.29
0.31
1.4
1.6
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
18
149
1.26
0.30
2.7
2.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
72
688
1.37
0.30
4.4
4.1
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
8
63
1.29
0.29
1.1
1.1
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
8
66
1.23
0.27
4.9
10.4
g/l
2.5
2.7
—
8
66
(3041096) Erythrocytes [Presence] in Urine by Automated
10
126
0.76
0.27
3.1
3.7
—
—
—
0
0
(3006598) pH of Arterial cord blood
5
72
0.67
0.27
1.0
1.0
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
20
170
1.23
0.27
3.1
3.4
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
12
96
1.29
0.25
1.2
1.7
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
5
37
1.37
0.24
9.6
25.5
%
0.6
0.8
—
5
37
(3020044) Glucose [Moles/volume] in Cerebral spinal fluid
5
37
1.37
0.24
3.6
5.7
mmol/l
3.3
3.3
—
5
37
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
5
40
1.26
0.23
3.8
5.4
mg/l
445.8
374.0
—
5
40
(3035637) Corticotropin [Mass/volume] in Plasma
5
40
1.26
0.23
1.2
2.0
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
15
126
1.23
0.22
2.1
1.6
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
12
98
1.26
0.22
2.7
2.3
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
5
42
1.20
0.22
1.2
1.6
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
0
10
0.00
0.21
0.0
4.1
—
—
—
0
0
(3007302) Hemoglobin [Mass/volume] in Mixed venous blood
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3038071) Oxygen [Partial pressure] in Mixed venous blood
0
11
0.00
0.21
0.0
2.9
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood
0
11
0.00
0.21
0.0
2.9
—
—
—
0
0
(3001964) Herpes simplex virus Ag [Presence] in Specimen
0
11
0.00
0.21
0.0
3.4
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
6
47
1.29
0.21
1.7
1.7
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
11
132
0.80
0.21
2.4
1.8
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
6
51
1.18
0.20
1.3
2.0
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
6
52
1.16
0.19
1.3
2.0
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
26
236
1.14
0.16
4.8
5.2
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
9
77
1.18
0.16
6.8
28.1
mmol/l
1.4
1.3
—
9
71
(3021601) Nitrite [Presence] in Urine by Test strip
29
266
1.13
0.16
4.5
5.7
estimate
0.0
0.0
—
5
49
(40760892) CBC W Ordered Manual Differential panel - Blood
14
121
1.18
0.15
13.5
6.5
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
10
116
0.84
0.13
4.4
3.6
u/l
54.2
62.3
—
10
107
(3029937) Albumin [Presence] in Urine by Test strip
15
133
1.15
0.12
3.5
4.3
estimate
0.0
0.0
—
5
48
(3009261) Glucose [Presence] in Urine by Test strip
29
271
1.10
0.10
3.4
4.0
estimate
0.0
0.0
—
5
45
(3002256) Pathology report gross observation
5
43
1.17
0.10
1.2
1.1
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
5
43
1.17
0.10
1.4
1.2
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
5
48
1.04
0.09
1.6
2.4
—
—
—
0
0
(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma
6
53
1.14
0.09
1.3
2.0
—
81.6
—
0
5
(3016879) Cocaine [Presence] in Urine
7
63
1.12
0.08
1.4
1.7
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
7
67
1.04
0.08
1.4
1.7
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
7
67
1.04
0.08
1.4
1.6
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
12
108
1.12
0.07
1.1
1.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
13
118
1.11
0.07
2.4
5.0
inr
0.9
1.1
—
6
28
(1761868) Lipid panel - Serum or Plasma
10
90
1.12
0.05
2.3
1.7
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
22
230
0.93
0.05
1.8
1.6
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
29
300
0.94
0.05
1.6
1.8
g/l
1.2
1.4
—
10
147
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
17
178
0.94
0.03
3.4
3.7
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
15
157
0.94
0.02
1.5
1.8
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
16
153
1.05
0.01
2.7
2.5
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
16
163
0.97
0.00
3.5
2.6
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
19
194
0.97
0.00
2.8
2.2
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(4211845)
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3042299) inFLIXimab [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
16.6
—
8.8
—
0
8
(3005082) Progesterone [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
33.8
—
0
8
(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3034368) Herpes virus 6 IgM Ab [Presence] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029536) Hepatitis C virus RNA [Units/volume] (viral load) in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4027681)
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3013180) HIV 1 RNA [Units/volume] (viral load) in Serum or Plasma by Probe with amplification
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035999) Lactate [Moles/volume] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.8
—
1.4
—
0
8
(3029075) Extractable nuclear Ab panel - Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043257) Herpes virus 6 IgG Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(1001833) Epstein Barr virus DNA [Units/volume] (viral load) in Blood by NAA with probe detection
0
6
0.00
0.00
0.0
11.0
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
0
6
0.00
0.00
0.0
8.0
—
257.3
—
0
6
(3036071) Salmonella sp Ab [Titer] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
7
0.00
0.00
0.0
1.1
—
13.3
—
0
7
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000722) Carnitine free (C0) [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.8
—
23.0
—
0
6
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(723473) SARS-CoV-2 (COVID-19) IgA Ab [Presence] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(723474) SARS-CoV-2 (COVID-19) IgG Ab [Presence] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3041672) Baker's yeast Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3042733) HLA Ab [Presence] in Serum
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
228.1
—
0
7
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
0.3
—
0
6
(3051651) Icteric interference index of Serum or Plasma
0
9
0.00
0.00
0.0
3.6
—
—
—
0
0
(3002621) Streptococcal DNAse B [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
6
65
0.91
0.00
1.5
1.7
—
—
—
0
0
(3012320) Pathologist interpretation of Cerebral spinal fluid tests
0
6
0.00
0.00
0.0
3.5
—
—
—
0
0
(21494262) English walnut recombinant (rJug r) 3 IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
2.6
—
0
6
(3028300) Cannabinoids [Presence] in Urine
7
68
1.03
0.00
1.4
1.6
—
—
—
0
0
(3034988) Calcium [Moles/volume] in Capillary blood
0
6
0.00
0.00
0.0
7.3
—
1.2
—
0
6
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
1378.3
—
0
7
(42870560) Thyrotropin [Units/volume] in Cord blood
8
87
0.91
0.00
1.0
1.0
mu/l
7.3
7.4
—
8
87
(3014038) Collagen crosslinked N-telopeptide [Moles/volume] in Urine
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation
0
7
0.00
0.00
0.0
1.1
—
200.7
—
0
7
(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3001820) Epstein Barr virus nuclear Ab [Presence] in Serum
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3013247) Albumin in CSF/Albumin in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
2.6
—
0
6
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3024474) Albumin [Mass/volume] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.1
—
108.8
—
0
9

Mortality – FinRegistry

Association

Association between endpoint P16_CHRONIC_RESPI_DISEA_ORIGINA_PERINA_PERIOD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_CHRONIC_RESPI_DISEA_ORIGINA_PERINA_PERIOD.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_CHRONIC_RESPI_DISEA_ORIGINA_PERINA_PERIOD – Chronic respiratory disease originating in the perinatal period

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data