Eclampsia

O15_ECLAMPSIA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O15
  • Hospital discharge: ICD-9 6426
  • Cause of death: ICD-10 O15
  • Cause of death: ICD-9 6426

2 out of 7 registries used, show all original rules.

93

4. Check minimum number of events

None

93

5. Include endpoints

None

93

6. Filter based on genotype QC (FinnGen only)

93

Control definitions (FinnGen only)

Control exclude
O15_OEDEM_PROTUR_HYPERT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF10
Parent code in ICD-10
O10-O16
Name in latin
Eclampsia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 602 602 -
Only index persons 597 597 -
Unadjusted period prevalence (%)
Whole population 0.02 0.02 -
Only index persons 0.02 0.02 -
Median age at first event (years)
Whole population - 28.59 -
Only index persons - 28.56 -

-FinnGen-

Key figures

All Female Male
Number of individuals 93 93 -
Unadjusted period prevalence (%) 0.03 0.03 -
Median age at first event (years) 29.23 29.23 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
85
Matched controls
848
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O15.0
ICD-10 Finland
Eclampsia in pregnancy
+∞
31.2
28
*
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
+∞
28.8
26
*
6426A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Eclampsia[ECLAMPSIA , ENNEN SYNNYTYSTÄ]
+∞
17.3
16
*
O15.1
ICD-10 Finland
Eclampsia in labour
+∞
16.1
15
*
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
+∞
13.9
13
*
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
+∞
11.7
11
*
6426B
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Eclampsia[ECLAMPSIA , SYNNYTYKSEN AIKANA]
+∞
11.7
11
*
O15.2
ICD-10 Finland
Eclampsia in the puerperium
+∞
10.6
10
*
O14.1
ICD-10 Finland
Severe pre-eclampsia
+∞
10.6
10
*
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
45.9
10.3
12
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
4.7
8.6
34
106
C07AG01
ATC
labetalol; systemic
+∞
8.5
8
*
8811
FHL
Cesarean section
7.6
7.4
17
27
6462A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Unspecified renal disease in pregnancy, without mention of hypertension
+∞
7.4
7
*
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
4.7
6.9
24
65

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3037522) Nuclear Ab [Titer] in Serum
33
131
3.35
6.73
1.4
1.5
titre
222.9
629.1
—
7
33
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
52
283
2.90
5.97
8.4
5.2
mmol/l
1.2
1.2
0.74
43
252
(3020682) Albumin/Creatinine [Ratio] in Urine
33
141
3.08
5.86
5.8
3.5
mg/mmol
22.2
5.4
0.51
25
80
(3003458) Phosphate [Moles/volume] in Serum or Plasma
18
55
3.82
5.35
9.7
4.3
mmol/l
1.0
1.0
0.07
18
48
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
35
162
2.86
5.32
2.2
1.8
mg/l
1.7
0.7
1.76
29
128
(3023368) Bacteria identified in Blood by Culture
29
128
2.84
4.75
3.0
3.1
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
35
177
2.57
4.36
1.4
1.3
iu/ml
12.1
27.0
—
7
67
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
57
362
2.48
4.33
4.5
3.8
—
—
—
0
0
(3018418) pH of Serum or Plasma
34
170
2.58
4.33
4.9
3.0
ph
7.4
7.4
—
6
23
(3012516) Albumin [Mass/volume] in Urine
29
136
2.65
4.18
5.1
2.9
mg/l
1791.9
641.4
0.28
23
78
(3022948) Iron [Moles/volume] in Serum or Plasma
22
91
2.86
4.01
3.8
2.0
umol/l
13.8
15.1
0.34
22
86
(3004789) Transferrin [Mass/volume] in Serum or Plasma
21
86
2.86
3.89
3.7
1.8
g/l
2.5
2.5
0.09
21
79
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
36
196
2.37
3.74
1.9
2.5
ng/l
7.8
16.7
4.17
15
85
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
23
103
2.64
3.59
2.0
3.3
ng/l
10.7
39.7
1.10
12
48
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
33
178
2.32
3.46
1.5
1.2
u/ml
1.7
9.1
1.48
20
82
(3026008) Bacteria identified in Urine by Culture
35
198
2.23
3.26
2.9
2.2
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
55
376
2.13
3.13
5.6
6.0
e9/l
0.5
0.5
0.44
50
338
(3032080) INR in Blood by Coagulation assay
33
185
2.21
3.12
2.5
3.9
inr
1.0
1.0
0.52
15
66
(3006315) Basophils [#/volume] in Blood
55
377
2.12
3.10
5.6
6.0
e9/l
0.0
0.0
0.33
50
337
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
7
12
6.21
3.08
1.6
1.3
—
—
—
0
0
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
5
5
10.46
3.01
1.0
1.8
umol/l
11.4
10.4
—
5
5
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
8
17
5.04
2.99
1.6
1.2
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
18
79
2.59
2.90
1.3
1.7
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
12
46
2.85
2.47
7.6
6.5
mmol/l
1.1
1.7
0.24
12
35
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
28
160
2.07
2.46
2.4
1.7
—
—
—
0
0
(3044889) 12 lead EKG panel
62
468
1.97
2.43
3.2
2.6
—
—
—
0
0
(3000991) Gas panel - Venous blood
9
28
3.45
2.38
8.9
5.2
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
34
214
1.93
2.26
1.3
1.2
u/ml
0.6
1.6
1.03
11
57
(3007853) Bacteria identified in Skin by Aerobe culture
16
75
2.37
2.24
1.9
1.4
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
6
14
4.50
2.19
2.0
1.4
—
—
—
0
0
(3019060) Gas panel - Arterial blood
8
25
3.40
2.15
8.4
5.3
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
10
38
2.83
2.08
1.7
2.3
g/l
0.2
0.2
—
10
38
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
12
51
2.55
2.05
1.3
1.7
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
7
21
3.52
2.01
4.9
8.3
%
0.9
0.8
—
7
21
(3014007) Fractional oxyhemoglobin in Arterial blood
7
21
3.52
2.01
4.9
8.3
%
94.7
94.9
—
7
21
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
7
21
3.52
2.01
4.9
8.3
%
1.4
1.3
—
7
21
(3038177) Helicobacter pylori Ab [Presence] in Serum
5
11
4.73
1.96
1.2
1.1
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
12
53
2.45
1.90
1.2
1.7
—
—
—
0
0
(40761535) Cells panel - Urine sediment
9
35
2.74
1.86
6.8
3.1
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
63
501
1.80
1.85
5.8
4.0
—
39.6
—
0
9
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
8
29
2.92
1.84
1.6
1.7
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
7
23
3.20
1.84
1.1
1.3
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
7
23
3.20
1.84
2.3
2.0
%
81.7
106.0
—
7
23
(3014148) Varicella zoster virus Ab [Titer] in Serum
6
18
3.49
1.77
1.3
1.3
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
8
30
2.82
1.77
5.4
1.8
kpa
5.2
5.6
—
8
30
(3029937) Albumin [Presence] in Urine by Test strip
29
187
1.80
1.74
4.2
2.8
estimate
0.0
0.0
—
10
73
(3020891) Body temperature
5
13
4.00
1.74
4.2
4.9
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
5
13
4.00
1.74
3.8
4.7
mmol/l
1.7
1.0
—
5
13
(3011397) Hemoglobin [Presence] in Urine by Test strip
25
154
1.85
1.73
5.8
3.0
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
66
539
1.77
1.70
5.7
3.9
—
—
—
0
0
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
6
19
3.30
1.69
6.0
1.4
mmol/l
24.3
24.8
—
6
19
(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum
8
32
2.64
1.64
1.1
1.2
—
15.4
—
0
6
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
8
32
2.64
1.64
1.4
2.0
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
12
57
2.27
1.63
1.5
1.3
u/ml
1078.9
101.7
0.61
12
49
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
20
3.13
1.61
10.7
8.4
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
8
33
2.55
1.58
2.1
1.3
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
11
51
2.31
1.57
1.4
1.1
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
35
245
1.69
1.56
5.3
5.7
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
33
228
1.69
1.54
2.9
1.8
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
5
15
3.46
1.54
1.0
1.3
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
32
220
1.69
1.52
5.1
2.6
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
6
22
2.84
1.46
1.3
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
6
22
2.84
1.46
1.3
1.2
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
6
22
2.84
1.46
2.3
2.5
%
155.7
141.2
—
6
22
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
6
23
2.72
1.39
6.0
4.0
mmol/l
24.0
25.0
—
6
23
(42529406) Shigella sp [Presence] in Stool by Culture
6
23
2.72
1.39
1.3
1.2
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
35
252
1.62
1.38
1.9
1.7
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
38
0.00
1.38
0.0
1.3
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
27
182
1.68
1.37
2.0
1.8
u/l
92.0
109.8
0.32
27
176
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
5
18
2.87
1.30
1.0
1.1
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
8
37
2.27
1.25
7.5
1.8
kpa
6.0
5.6
—
8
37
(3002032) Base excess in Venous blood by calculation
8
37
2.27
1.25
7.5
1.8
mmol/l
1.3
2.1
—
8
26
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
29
206
1.59
1.19
1.8
1.7
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
26
180
1.62
1.18
5.3
4.5
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
14
81
1.86
1.17
1.5
2.2
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
5
20
2.58
1.16
3.2
1.5
%
0.9
0.7
—
5
20
(3012544) pH of Venous blood
8
40
2.09
1.15
7.5
1.7
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
7
30
2.44
1.15
1.7
1.3
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
7
31
2.36
1.13
1.9
1.3
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
8
41
2.04
1.12
2.5
1.6
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
84
774
1.88
1.11
15.6
8.5
mmol/l
139.4
139.8
1.23
84
755
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
32
236
1.54
1.11
2.0
1.9
pmol/l
111.4
100.4
0.46
15
125
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
7
32
2.28
1.11
1.4
1.6
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
5
21
2.46
1.10
3.2
1.6
%
1.3
0.9
—
5
21
(3007164) IgA [Mass/volume] in Serum or Plasma
28
201
1.56
1.09
1.3
1.3
g/l
1.8
2.1
0.76
21
126
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
9
45
2.11
1.08
1.4
1.6
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
7
34
2.14
1.05
3.1
1.6
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
7
34
2.14
1.05
1.4
1.4
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
46
372
1.47
1.01
5.4
3.0
estimate
0.0
0.0
—
9
72
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
38
296
1.48
1.01
4.9
2.8
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
84
778
1.82
1.00
15.8
8.5
mmol/l
3.9
3.9
0.11
84
756
(3023511) Choriogonadotropin [Units/volume] in Urine
10
55
1.92
0.96
1.3
1.1
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
34
262
1.47
0.94
1.5
1.4
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
23
164
1.53
0.91
6.0
2.9
kg/l
1.0
1.0
—
5
21
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
6
29
2.14
0.91
1.0
1.7
g/l
0.2
0.2
—
6
29
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
6
113
0.50
0.90
1.3
1.6
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
80
733
1.65
0.88
12.5
7.9
ml/min/173m2
90.3
92.2
0.29
66
588
(3030467) Casts [#/volume] in Urine by Automated count
24
175
1.50
0.86
5.6
2.4
e6/l
0.1
0.2
0.36
18
122
(36304419) Bacteria [Presence] in Urine
25
184
1.49
0.86
4.0
2.3
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
6
31
2.00
0.86
1.2
2.9
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
6
31
2.00
0.86
7.5
2.5
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
16
106
1.62
0.86
5.8
2.2
e6/l
0.4
0.9
—
10
54
(3009261) Glucose [Presence] in Urine by Test strip
45
372
1.41
0.84
5.5
3.0
estimate
0.0
0.0
—
8
73
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
6
32
1.93
0.83
1.0
1.6
g/l
1.3
1.2
—
6
32
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
15
101
1.58
0.76
5.9
2.3
e6/l
3.1
4.0
—
9
50
(3034770) Mitochondria Ab [Titer] in Serum
5
24
2.14
0.76
1.0
1.3
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
5
24
2.14
0.76
1.2
1.5
—
—
—
0
0
(40758558) Short blood count panel - Blood
27
207
1.43
0.75
7.2
7.4
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
22
162
1.47
0.75
1.7
1.7
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
44
368
1.37
0.74
7.9
4.5
estimate
0.0
0.0
—
10
73
(3004119) Hemoglobin [Mass/volume] in Venous blood
5
25
2.05
0.74
4.4
1.8
g/l
115.8
139.4
—
5
25
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
5
27
1.90
0.69
1.4
1.9
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
5
27
1.90
0.69
1.4
1.9
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
11
70
1.65
0.69
1.6
1.5
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
10
62
1.69
0.68
1.3
1.2
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
28
1.83
0.67
1.4
1.1
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
5
29
1.76
0.65
2.0
1.5
—
—
—
0
0
(40768443) Skin Pathology biopsy report
5
29
1.76
0.65
1.0
1.1
—
—
—
0
0
(3015736) pH of Urine
36
298
1.34
0.63
5.8
2.7
—
—
—
0
0
(4010399)
8
50
1.66
0.63
1.0
1.3
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
8
51
1.62
0.62
1.3
1.5
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
11
72
1.60
0.62
3.6
3.3
pmol/l
4.5
4.7
0.42
11
66
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
5
30
1.70
0.62
1.4
1.3
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
25
197
1.37
0.59
5.4
2.4
e6/l
13.7
58.7
0.79
19
144
(3036481) Cortisol [Moles/volume] in Serum or Plasma
5
88
0.54
0.59
2.2
1.8
nmol/l
329.2
388.3
—
5
83
(3000570) Elastase.pancreatic [Mass/mass] in Stool
0
23
0.00
0.59
0.0
1.2
—
380.9
—
0
8
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
6
38
1.62
0.55
1.2
1.5
pmol/l
57.8
46.1
—
6
38
(3008898) HLA-B27 [Presence]
9
64
1.45
0.53
1.1
1.1
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
10
143
0.66
0.53
1.2
1.5
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
9
65
1.43
0.52
7.0
4.5
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
30
249
1.30
0.51
1.9
2.0
—
—
—
0
0
(3022621) pH of Urine by Test strip
7
48
1.49
0.48
3.4
2.2
—
—
—
0
0
(3022145) Colonoscopy Study observation
11
78
1.47
0.45
1.0
1.3
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
29
244
1.27
0.44
6.1
3.1
e6/l
4.8
43.4
0.97
20
152
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
29
244
1.27
0.44
1.7
1.7
—
—
—
0
0
(3000492) Spirometry study
10
70
1.48
0.44
1.3
1.3
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
5
31
1.65
0.44
1.0
1.1
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
8
57
1.44
0.43
1.4
1.5
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
8
58
1.41
0.43
1.0
1.0
—
—
—
0
0
(3026725) Estradiol (E2) [Moles/volume] in Serum or Plasma
5
33
1.54
0.42
1.4
1.6
nmol/l
0.4
0.4
—
5
26
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
14
108
1.35
0.38
1.6
1.6
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
6
41
1.49
0.37
1.2
1.0
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
83
797
1.39
0.36
14.6
9.6
mg/l
17.5
18.4
0.11
70
588
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
11
82
1.39
0.36
1.4
1.3
iu/ml
294.2
150.8
—
6
36
(3009542) Hematocrit [Volume Fraction] of Blood
80
766
1.32
0.34
19.0
11.4
%
38.7
40.0
1.02
66
646
(3041096) Erythrocytes [Presence] in Urine by Automated
27
232
1.23
0.34
3.5
2.6
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
11
83
1.37
0.34
1.9
1.6
nmol/l
1120.1
1069.1
0.09
11
65
(3017143) Hepatitis C virus Ab [Presence] in Serum
15
120
1.30
0.32
1.9
1.5
—
—
—
0
0
(3019225) pH of Specimen
7
55
1.29
0.31
4.0
4.9
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
73
695
1.23
0.30
3.8
4.0
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
15
122
1.27
0.29
1.3
1.3
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
9
75
1.22
0.26
1.4
1.3
—
—
—
0
0
(3002256) Pathology report gross observation
13
106
1.26
0.25
1.5
1.2
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
7
91
0.75
0.24
3.1
1.7
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
7
93
0.73
0.23
1.4
1.1
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
0
12
0.00
0.21
0.0
4.9
—
—
—
0
0
(3023420) DNA double strand Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
13
0.00
0.21
0.0
3.7
—
19.5
—
0
13
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
21
185
1.17
0.20
1.8
1.8
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
7
62
1.14
0.18
1.9
1.4
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
5
66
0.74
0.17
2.2
2.0
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
7
88
0.78
0.15
1.3
1.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
38
360
1.09
0.11
2.2
1.8
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
31
329
0.91
0.11
3.0
2.3
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
5
45
1.12
0.10
9.6
3.7
—
0.0
—
0
12
(3025159) Blasts/100 leukocytes in Blood
5
47
1.07
0.09
9.6
3.5
—
0.0
—
0
10
(3002179) Metamyelocytes/100 leukocytes in Blood
5
48
1.04
0.09
9.6
3.4
—
0.6
—
0
9
(4035726)
6
53
1.14
0.09
1.7
1.2
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
12
107
1.14
0.09
1.0
1.2
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
6
56
1.08
0.09
1.7
1.6
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
9
83
1.09
0.07
2.4
2.2
—
23.3
—
0
5
(3013512) EKG study
17
159
1.08
0.05
2.8
2.5
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
13
124
1.06
0.01
1.3
1.8
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
10
98
1.02
0.00
1.3
1.6
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
11
113
0.97
0.00
1.7
2.2
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
21
207
1.02
0.00
2.0
2.0
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
0
5
0.00
0.00
0.0
1.2
—
1.4
—
0
5
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
27.5
—
0
5
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
6
64
0.93
0.00
1.7
1.5
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
4.2
—
371.6
—
0
5
(3010838) Calcium [Moles/time] in 24 hour Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
6
64
0.93
0.00
1.7
1.5
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(40759040) C peptide [Moles/volume] in Serum or Plasma --post meal
0
5
0.00
0.00
0.0
1.0
—
1.3
—
0
5
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3029536) Hepatitis C virus RNA [Units/volume] (viral load) in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3034426) Prothrombin time (PT)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
6
0.00
0.00
0.0
2.8
—
142.7
—
0
6
(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
8
0.00
0.00
0.0
2.3
—
3.9
—
0
8
(3017181) Myelocytes/100 leukocytes in Blood
5
49
1.02
0.00
9.6
3.5
—
0.7
—
0
13
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
5
56
0.89
0.00
1.8
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
6
65
0.92
0.00
1.7
1.4
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3016244) Insulin [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.5
—
10.2
—
0
6
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
1.0
—
155.7
—
0
6
(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.3
—
1855.9
—
0
7
(3005033) Fetal Nuchal fold Thickness US
5
55
0.90
0.00
1.8
1.4
—
—
—
0
0
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
6
60
1.00
0.00
2.2
2.3
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
6
65
0.92
0.00
1.7
1.4
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
0
8
0.00
0.00
0.0
2.3
—
106.1
—
0
8
(40760888) Immunoglobulin light chains.free panel - Serum
0
8
0.00
0.00
0.0
5.3
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
7
70
1.00
0.00
1.7
1.6
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_ECLAMPSIA and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_ECLAMPSIA.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_ECLAMPSIA – Eclampsia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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