Other deformities of toe(s)

M13_TOEDEFORMOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M20.5, M20.6
  • Hospital discharge: ICD-9 735[8-9]
  • Cause of death: ICD-10 M20.5, M20.6
  • Cause of death: ICD-9 735[8-9]

2 out of 7 registries used, show all original rules.

1348

4. Check minimum number of events

None

1348

5. Include endpoints

None

1348

6. Filter based on genotype QC (FinnGen only)

1348

Control definitions (FinnGen only)

Control exclude
M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8220 6036 2146
Only index persons 7684 5724 1960
Unadjusted period prevalence (%)
Whole population 0.14 0.17 0.06
Only index persons 0.18 0.21 0.07
Median age at first event (years)
Whole population 55.11 55.37 54.28
Only index persons 54.47 54.78 53.58

-FinnGen-

Key figures

All Female Male
Number of individuals 1348 1027 321
Unadjusted period prevalence (%) 0.30 0.35 0.14
Median age at first event (years) 56.12 55.59 57.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1212
Matched controls
12120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M20.5
ICD-10 Finland
Other deformities of toe(s) (acquired)
14758.1
323.0
929
*
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
257.7
323.0
387
22
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
4931.8
323.0
365
*
M20.1
ICD-10 Finland
Hallux valgus (acquired)
104.2
323.0
477
75
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
33.1
270.3
362
154
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
262.3
242
*
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
936.8
241.4
229
*
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
224.1
208
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
21.5
201.8
308
189
M19.0
ICD-10 Finland
Primary arthrosis of other joints
48.7
186.7
227
57
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
891.9
162.6
156
*
WX320
NOMESCO Finland
Spinalanesthesy
7.5
159.0
436
840
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
1725.6
156.8
149
*
7358X
ICD-9 Finland
Acquired deformities of toe, Other acquired deformities of toe
+∞
152.4
143
*
M20.2
ICD-10 Finland
Hallux rigidus
420.0
151.7
149
*
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
1634.8
150.2
143
*
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
47.8
147.5
180
44
NHG82
NOMESCO Finland
Fusion of other tarsal joint
+∞
143.6
135
*
M25.5
ICD-10 Finland
Pain in joint
6.1
143.1
474
1152
M20.6
ICD-10 Finland
Acquired deformity of toe(s), unspecified
+∞
141.5
133
*
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
147.1
136.5
143
11
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
22.5
132.0
196
103
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
77.0
121.6
137
20
9271
FHL
Hallux surgery
290.3
105.6
106
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
14.1
99.9
177
145
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
187.3
99.9
103
6
9273
FHL
Other surgery for toe deformity or pain condition, e.g., Morton, hammer toe
350.5
96.4
96
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
11.6
93.7
182
181
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
+∞
91.8
87
*
N02AX02
ATC
tramadol; systemic, rectal
3.5
87.1
600
2662
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
899.9
86.7
84
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.4
85.1
643
3043
M01AH05
ATC
etoricoxib; oral
3.3
84.4
790
4367
M77.4
ICD-10 Finland
Metatarsalgia
10.3
84.1
174
194
L17
ICPC
Foot/toe symptom/complaint
3.8
83.7
456
1659
M16.1
ICD-10 Finland
Other primary coxarthrosis
20.7
80.7
122
65
7350A
ICD-9 Finland
Acquired deformities of toe, Hallux valgus (acquired)
+∞
76.9
73
*
M01AX05
ATC
glucosamine; oral
4.3
75.5
326
950
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
11.6
70.8
136
130
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
717.8
69.8
68
*
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
101.3
69.8
76
8
M79.6
ICD-10 Finland
Pain in limb
3.1
69.1
527
2398
N02AJ06
ATC
codeine and paracetamol; systemic
3.1
68.7
515
2311
73799
ICD-8 Finland
Hallux valgus and varus
+∞
67.3
64
*
S18
ICPC
Laceration/cut
2.9
65.7
597
3025
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
107.6
65.6
71
7
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
26.3
62.9
88
36
L84
ICD-10 Finland
Corns and callosities
11.2
60.9
119
117
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
80.1
60.7
68
9
P01BA02
ATC
hydroxychloroquine; oral
9.6
58.8
125
144
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
28.4
58.6
80
30
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
17.0
57.6
93
59
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
28.6
57.2
78
29
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
6.9
50.4
133
214
NHK68
NOMESCO Finland
Shortening or lengthening osteotomy of ankle or foot
+∞
50.4
48
*
A07EC01
ATC
sulfasalazine; oral, rectal
8.8
46.6
103
126
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
104.2
46.1
50
5
N02BE01
ATC
paracetamol; systemic, rectal
3.2
45.9
1073
8556
ZXA05
NOMESCO Finland
Left side
2.8
45.7
355
1543
9279
FHL
Other measure in this category
464.4
45.6
45
*
ZXA00
NOMESCO Finland
Right side
2.8
45.5
369
1645
SPAT1153
SPAT
Removal of sutures
2.6
44.8
440
2191
N03AX16
ATC
pregabalin; oral
2.9
44.7
326
1358
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.5
44.2
235
782
B01AB05
ATC
enoxaparin; parenteral
2.7
43.6
384
1789
L15
ICPC
Knee symptom/complaint
3.2
43.4
269
1001
M01AB05
ATC
diclofenac; systemic, rectal
2.4
43.2
828
5762
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.6
42.4
389
1854
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
7.1
42.4
108
165
M01AE02
ATC
naproxen; oral, rectal
2.3
41.8
712
4639
WX111
NOMESCO Finland
Local infiltration anesthesia
421.3
41.4
41
*
NF1AA
NOMESCO Finland
Hip X-ray examination
5.9
40.5
119
220
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.8
40.0
310
1329
M01AX17
ATC
nimesulide; oral
2.7
40.0
344
1569
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
5.4
39.2
124
250
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
11.5
39.1
74
68
M01AH01
ATC
celecoxib; oral (coxibs)
3.1
38.8
250
949
M48.0
ICD-10 Finland
Spinal stenosis
3.8
38.8
180
532
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
389.1
38.2
38
*
M01AC06
ATC
meloxicam; systemic, rectal
2.3
37.2
474
2641
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
84.9
37.0
41
5
7359X
ICD-9 Finland
Acquired deformities of toe, Unspecified acquired deformity of toe
+∞
36.6
35
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
36.4
491
2801
TQW40
NOMESCO Finland
Remowal of suture of skin
4.8
36.3
128
291
M01AH02
ATC
rofecoxib; oral
3.4
36.2
198
664
NHL20
NOMESCO Finland
Myotomy or tenotomy of foot
190.6
36.0
37
*
H02AB06
ATC
prednisolone; systemic
2.2
35.5
565
3466
J01DB01
ATC
cefalexin; oral
2.5
35.4
995
7883
NG2AA
NOMESCO Finland
Patella X-ray examination
44.5
35.2
43
10
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
4.6
34.3
126
298
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
43.4
34.2
42
10
M54.5
ICD-10 Finland
Low back pain
2.3
34.2
417
2254
G57.6
ICD-10 Finland
Lesion of plantar nerve
10.5
33.9
67
67
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
47.0
33.9
41
9
M09AX01
ATC
hyaluronic acid; parenteral
9.6
33.7
70
77
M01AE01
ATC
ibuprofen; systemic, rectal
2.8
33.2
1083
9076
M13.9
ICD-10 Finland
Arthritis, unspecified
8.8
33.0
72
86
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
36.2
33.0
42
12
M22.4
ICD-10 Finland
Chondromalacia patellae
45.8
32.9
40
9
L88
ICPC
Rheumatoid/seropositive arthritis
14.7
32.7
55
39
7354A
ICD-9 Finland
Acquired deformities of toe, Other hammer toe (acquired)
+∞
32.4
31
*
NHQ40
NOMESCO Finland
Amputation of toe
16.4
32.3
52
33
NHE80
NOMESCO Finland
Incsion and freeing of capsule of toe joint
+∞
31.4
30
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.4
31.0
162
523
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
164.2
30.8
32
*
M15
ICD-10 Finland
Polyarthrosis
6.0
30.7
87
153
L04AA13
ATC
leflunomide; oral
52.9
30.5
36
7
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
30.3
29
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.7
30.1
143
427
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
6.3
30.0
82
138
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
309.7
29.9
30
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
29.5
160
530
B01AF01
ATC
rivaroxaban; oral
3.7
29.5
138
407
ACC19
NOMESCO Finland
Transcision of peripheral nerve: other or unspecified
24.9
29.3
41
17
NK4EA
NOMESCO Finland
Joint X-ray examintion with load or wrench not elsewhere classified
+∞
29.3
28
*
L90
ICPC
Osteoarthrosis of knee
6.6
29.1
77
124
M19.8
ICD-10 Finland
Other specified arthrosis
9.0
29.0
62
72
A02BC02
ATC
pantoprazole; systemic
2.0
28.8
786
5806
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
16.4
28.7
46
29
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.2
28.5
91
185
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
11.2
28.5
54
50
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
+∞
28.2
27
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.6
28.1
138
423
M70.6
ICD-10 Finland
Trochanteric bursitis
3.0
28.0
180
670
N03AX12
ATC
gabapentin; oral
2.8
28.0
199
792
M19.2
ICD-10 Finland
Other secondary arthrosis
+∞
27.2
26
*
M23.8
ICD-10 Finland
Other internal derangements of knee
18.1
27.2
42
24
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.8
26.9
186
727
L13
ICPC
Hip symptom/complaint
2.8
26.8
192
765
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
276.9
26.8
27
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
14.6
26.8
45
32
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
19.6
26.6
40
21
L08
ICPC
Shoulder symptom/complaint
2.5
26.4
237
1074
J01FF01
ATC
clindamycin; systemic
2.2
26.4
341
1847
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
26.4
26.3
36
14
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
18.8
26.2
40
22
1220
FHL
Arthroscopy
11.0
26.2
50
47
TNX39
NOMESCO Finland
Other orthopedic bandage, unspecified region
10.6
26.2
51
50
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
+∞
26.1
25
*
L28
ICPC
Limited function/disability (L)
2.7
26.1
200
830
J01AA02
ATC
doxycycline; systemic
2.1
26.0
944
7626
SPAT1229
SPAT
Assessment of need for aid
3.7
25.6
120
354
WX214
NOMESCO Finland
Plexus blockade at the ankle
59.3
25.1
29
5
M01CB01
ATC
sodium aurothiomalate; parenteral
+∞
25.1
24
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.9
24.9
161
601
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
24.0
24.9
35
15
L03
ICPC
Low back symptom/complaint
2.2
24.6
306
1624
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.9
24.5
82
176
M02AA07
ATC
piroxicam; topical
2.0
24.4
450
2802
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
7.0
24.1
60
89
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
23.3
24.0
34
15
M03BC51
ATC
orphenadrine, combinations; systemic
2.1
23.9
353
2011
M20.3
ICD-10 Finland
Other deformity of hallux (acquired)
88.5
23.7
26
*
J01DA01
ATC
[U] cefalexin; systemic
1.9
23.7
748
5620
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
12.0
23.6
43
37
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
18.5
23.6
36
20
M03BX02
ATC
tizanidine; oral
1.9
23.5
729
5435
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
3.5
23.2
116
360
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
23.1
334
1881
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
+∞
23.0
22
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.7
22.9
170
689
A02BC05
ATC
esomeprazole; systemic
1.9
22.9
496
3258
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
22.7
343
1966
M01AE03
ATC
ketoprofen; systemic, rectal
1.9
22.2
438
2776
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
53.1
22.1
26
5
H02AB07
ATC
prednisone; oral
2.5
22.1
185
800
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
21.9
490
3242
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.5
21.9
107
326
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
117.1
21.6
23
*
N06AA09
ATC
amitriptyline; systemic
2.9
21.5
144
546
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
21.5
529
3603
NHM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of ankle or foot
23.6
21.3
30
13
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
21.2
21.3
31
15
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
12.2
21.1
38
32
L16
ICPC
Ankle symptom/complaint
2.9
21.0
137
510
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
12.7
20.9
37
30
M19.9
ICD-10 Finland
Arthrosis, unspecified
6.6
20.8
54
85
J01CA04
ATC
amoxicillin; systemic
1.9
20.8
946
7858
NH3EA
NOMESCO Finland
Feet X-ray examination with load
17.3
20.5
32
19
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
20.4
482
3224
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.4
20.4
105
333
R03AC02
ATC
salbutamol; inhalant
1.8
20.3
604
4353
X59
ICD-10 Finland
Exposure to unspecified factor
2.3
19.9
200
952
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
74.7
19.7
22
*
B01AX06
ATC
[U] rivaroxaban; oral
29.5
19.7
26
9
WZA90
NOMESCO Finland
Other doctors statement
2.1
19.7
261
1407
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
3.7
19.6
88
250
A02BC03
ATC
lansoprazole; oral
1.9
19.6
358
2182
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
6.3
19.6
52
85
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
19.8
19.6
29
15
N06AX21
ATC
duloxetine; oral
2.7
19.5
137
537
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
10.3
19.4
38
38
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
26.5
19.2
26
10
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
4.0
19.1
78
204
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
19.1
411
2650
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.7
19.1
141
567
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.4
18.9
70
167
R06.0
ICD-10 Finland
Dyspnoea
2.0
18.9
284
1609
WX002
NOMESCO Finland
Sedation and analgesia
2.2
18.8
226
1162
WX702
NOMESCO Finland
Supraglottic ventilation device
3.8
18.7
81
224
9272
FHL
Metatarsophalangeal joint resection
192.8
18.6
19
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
18.5
422
2769
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.8
18.4
80
222
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
18.3
339
2067
SAA02
NOMESCO Finland
Basic examination of mouth
1.7
18.3
718
5551
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.0
18.1
74
194
J02AC01
ATC
fluconazole; systemic
1.7
18.1
523
3691
R01AD09
ATC
mometasone; nasal
1.7
18.0
528
3739
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
17.8
214
1102
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
+∞
17.7
17
*
73805
ICD-8 Finland
Other deformities, Digitus malleus
+∞
17.7
17
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.6
17.6
82
241
ZXA10
NOMESCO Finland
Bilateral
2.1
17.4
237
1284
M02AA10
ATC
ketoprofen; topical
2.2
17.2
193
964
R52.9
ICD-10 Finland
Pain, unspecified
2.9
17.1
111
411
M01AB55
ATC
diclofenac, combinations; oral
3.3
17.0
89
286
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.4
17.0
86
270
J01FA09
ATC
clarithromycin; systemic
1.8
17.0
371
2387
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
26.0
16.9
23
9
NG1DA
NOMESCO Finland
X-ray of knees
26.0
16.9
23
9
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
16.9
792
6375
J01FA10
ATC
azithromycin; systemic
1.7
16.8
662
5068
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.8
16.8
56
121
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
15.3
16.7
27
18
R06AE07
ATC
cetirizine; oral
1.7
16.4
513
3666
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
16.4
316
1946
SPAT1211
SPAT
Application of soft bandage
2.6
16.3
121
487
M10.9
ICD-10 Finland
Gout, unspecified
4.8
16.3
54
116
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.1
16.2
64
163
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.9
16.2
68
183
J01MA02
ATC
ciprofloxacin; systemic
1.7
16.2
424
2874
M21.6
ICD-10 Finland
Other acquired deformities of ankle and foot
48.2
16.0
19
*
R01AD08
ATC
fluticasone; nasal
1.8
15.8
335
2125
TNG10
NOMESCO Finland
Puncture of knee
+∞
15.7
15
*
NHU10
NOMESCO Finland
Removal of external fixation device from ankle or foot
17.5
15.6
24
14
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
86.2
15.6
17
*
E0000UV
ATC
NA
1.7
15.6
455
3179
9102
FHL
Trepanation or removal of the local bone process
22.4
15.6
22
10
9351
FHL
Metatarsus osteotomies
162.0
15.5
16
*
NHG22
NOMESCO Finland
Fusion of subtalar joint
162.0
15.5
16
*
N06AX11
ATC
mirtazapine; oral
1.8
15.4
362
2368
1221
FHL
Arthroscopy and meniscus surgery
15.0
15.4
25
17
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.5
15.3
127
545
Z47.8
ICD-10 Finland
Other specified orthopaedic follow-up care
16.3
15.3
24
15
NF1DA
NOMESCO Finland
X-ray of hips
18.0
15.2
23
13
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
15.1
129
562
G04BD08
ATC
solifenacin; oral
2.9
14.9
94
342
SPAT1310
SPAT
Counselling related to known health issue
1.7
14.9
371
2466
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
14.9
383
2569
M67.4
ICD-10 Finland
Ganglion
3.0
14.8
89
314
1223
FHL
Arthroscopy and articular cartilage surgery
57.4
14.8
17
*
H02BX01
ATC
methylprednisolone, combinations; systemic
3.3
14.7
76
243
P01AB01
ATC
metronidazole; oral, rectal
1.7
14.7
469
3344
S20
ICPC
Corn/callosity
6.4
14.6
38
61
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
14.5
93
343
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
14.3
271
1650
NH1AD
NOMESCO Finland
Ankle and foot CT
7.5
14.3
33
45
NH3AA
SPAT
NA
5.0
14.3
45
92
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
5.3
14.2
43
84
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
14.1
565
4265
SPAT1202
SPAT
Intra-articular injection
6.0
14.0
38
65
M79.7
ICD-10 Finland
Fibromyalgia
4.7
14.0
47
103
WX110
NOMESCO Finland
Local anesthesy
1.6
13.9
764
6239
X58
ICD-10 Finland
Exposure to other specified factors
2.3
13.9
139
653
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.6
13.9
625
4851
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
54.0
13.8
16
*
M01AC01
ATC
piroxicam; systemic, rectal
2.1
13.8
165
841
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.3
13.8
138
650
D01BA02
ATC
terbinafine; oral; topical
1.8
13.7
276
1710
M19
ICD-10 Finland
Other arthrosis
6.3
13.7
36
59
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.0
13.7
79
273
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
13.6
240
1422
M25.2
ICD-10 Finland
Flail joint
+∞
13.6
13
*
NHG88
NOMESCO Finland
Fusion of several tarsal joints
+∞
13.6
13
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.6
13.5
99
397
L04AB01
ATC
etanercept; parenteral
34.4
13.5
17
5
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.3
13.5
67
208
M47.9
ICD-10 Finland
Spondylosis, unspecified
4.5
13.5
47
107
NGE10
NOMESCO Finland
Incision or suture of capsule of knee joint
141.5
13.5
14
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.3
13.4
124
562
Z00.0
ICD-10 Finland
General medical examination
1.9
13.4
211
1200
J01FA06
ATC
roxithromycin; oral
1.6
13.4
454
3270
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
13.3
247
1490
ZSN00
NOMESCO Finland
Procedure related to previous procedure classified in chapter N
40.5
13.2
16
*
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
6.6
13.1
33
51
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
13.1
319
2093
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
13.0
203
1150
S97
ICPC
Chronic ulcer skin
3.3
13.0
66
209
H02AB04
ATC
methylprednisolone; systemic
2.0
13.0
175
938
S83.2
ICD-10 Finland
Tear of meniscus, current
3.5
12.9
61
183
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.8
12.9
85
321
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
50.5
12.9
15
*
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
8.2
12.8
28
35
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
12.8
249
1522
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
12.8
181
988
K02.1
ICD-10 Finland
Caries of dentine
1.6
12.8
608
4745
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
12.8
201
1143
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.2
12.7
142
703
M23.3
ICD-10 Finland
Other meniscus derangements
32.4
12.6
16
5
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.8
12.6
81
300
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
24.6
12.5
17
7
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
24.6
12.5
17
7
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
7.0
12.4
30
44
G44.2
ICD-10 Finland
Tension-type headache
2.1
12.4
155
803
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.6
12.4
56
162
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.6
12.4
490
3647
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
12.3
514
3873
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.6
12.3
88
349
SPAT1216
SPAT
Assessment of functional ability
2.0
12.2
169
913
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
5.2
12.2
37
73
A02BA02
ATC
ranitidine; systemic
1.8
12.2
228
1374
L12
ICPC
Hand/finger symptom/complaint
2.0
12.1
153
798
L99
ICPC
Musculoskeletal disease other
6.7
12.1
30
46
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
12.0
124
590
L04AB04
ATC
adalimumab; parenteral
10.2
12.0
23
23
A02BC01
ATC
omeprazole; systemic
1.7
12.0
297
1951
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.0
11.9
161
862
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
11.9
592
4639
M01AH03
ATC
valdecoxib; oral
2.8
11.8
77
288
G04BD12
ATC
mirabegron; oral
2.3
11.8
116
543
Z01.2
ICD-10 Finland
Dental examination
1.6
11.8
438
3202
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.3
11.7
108
491
R06AX22
ATC
ebastine; oral
1.8
11.6
202
1186
NHG20
NOMESCO Finland
Fusion of talocrural joint
65.6
11.6
13
*
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
65.6
11.6
13
*
M96.0
ICD-10 Finland
Pseudarthrosis after fusion or arthrodesis
65.6
11.6
13
*
NBB20
NOMESCO Finland
Primary total prosthetic replacement of humero-scapular joint
23.1
11.6
16
7
ACC51
NOMESCO Finland
Release of median nerve
2.9
11.5
71
256
73804
ICD-8 Finland
Other deformities, Hallux rigidus
+∞
11.5
11
*
M21.1
ICD-10 Finland
Varus deformity, not elsewhere classified
+∞
11.5
11
*
M15.8
ICD-10 Finland
Other polyarthrosis
6.8
11.5
28
42
NGB10
NOMESCO Finland
Primary partial prosthetic replacement of knee joint, demi prosthesis
121.1
11.4
12
*
AC00C
NOMESCO Finland
NA
121.1
11.4
12
*
M79.1
ICD-10 Finland
Myalgia
2.1
11.4
140
721
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
6.4
11.4
29
46
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
3.1
11.2
60
198
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
11.2
187
1081
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.3
11.2
104
470
SPAT1263
SPAT
Sampling
1.5
11.2
468
3506
A01
ICPC
Pain general/multiple sites
2.5
11.2
91
388
SPAT1312
SPAT
General health counselling
1.6
11.1
353
2470
UJF32
NOMESCO Finland
Coloscopy
1.7
11.1
282
1858
R51.80
ICD-10 Finland
Headache
2.0
11.1
157
857
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.3
11.1
54
167
AA1AD
NOMESCO Finland
CT of head and brain
1.7
11.0
253
1622
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
11.0
250
1597
M24.2
ICD-10 Finland
Disorder of ligament
43.7
10.9
13
*
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
3.0
10.9
62
212
J01MA12
ATC
levofloxacin; systemic
1.8
10.9
198
1180
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.1
10.9
59
197
R03DC03
ATC
montelukast; oral
1.9
10.6
175
1005
A46
ICD-10 Finland
Erysipelas
2.0
10.6
134
700
TNH31
NOMESCO Finland
Prefabricated orthosis, ankle or foot
10.1
10.5
20
20
NBG00
NOMESCO Finland
Plastic operation on acromioclavicular joint
14.3
10.5
17
12
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
110.9
10.4
11
*
M07.3
ICD-10 Finland
Other psoriatic arthropathies
+∞
10.4
10
*
ZX140
NOMESCO Finland
Intra articular
+∞
10.4
10
*
M21.0
ICD-10 Finland
Valgus deformity, not elsewhere classified
+∞
10.4
10
*
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
+∞
10.4
10
*
J02AC02
ATC
itraconazole; systemic
1.8
10.3
212
1309
R4180
NOMESCO Finland
Podiatric therapy
10.7
10.3
19
18
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.9
10.3
153
850
9245
FHL
Reconstruction or plastic surgery of ankle ligaments
19.0
10.3
15
8
M54.3
ICD-10 Finland
Sciatica
2.8
10.3
66
247
J31.0
ICD-10 Finland
Chronic rhinitis
2.3
10.2
93
419
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.1
10.2
55
183
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
10.2
402
2951
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
10.2
564
4466
L29
ICPC
Musculoskeletal sympt/complt other
2.5
10.2
82
348
L89
ICPC
Osteoarthrosis of hip
6.3
10.2
26
42
N05CF01
ATC
zopiclone; oral
1.6
10.2
356
2544
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.2
10.1
105
505
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
8.5
10.1
21
25
R35
ICD-10 Finland
Polyuria
2.7
10.1
67
255
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
10.0
226
1436
N05CF02
ATC
zolpidem; oral
1.7
10.0
203
1251
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
10.0
133
708
NB1AD
NOMESCO Finland
Shoulder CT examination
8.2
9.8
21
26
TNH33
NOMESCO Finland
Custom moulded brace, ankle or foot
5.7
9.8
27
48
M47.82
ICD-10 Finland
Other spondylosis, cervical region
3.3
9.8
49
155
M43.1
ICD-10 Finland
Spondylolisthesis
3.3
9.8
49
155
R4110
NOMESCO Finland
Physiotherapy
1.6
9.8
266
1781
D07AC01
ATC
betamethasone; topical
1.5
9.7
356
2568
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.5
9.7
76
319
N06AB04
ATC
citalopram; systemic
1.7
9.7
248
1631
1222
FHL
Arthroscopy and synovial surgery
55.4
9.7
11
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.3
9.6
34
80
G47.3
ICD-10 Finland
Sleep apnoea
1.8
9.5
186
1129
A02BC04
ATC
rabeprazole; oral
2.2
9.5
101
491
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
4.9
9.5
30
63
M01AX01
ATC
nabumetone; oral
3.1
9.5
50
165
WX204
NOMESCO Finland
Axillary plexus blockaced
3.9
9.5
37
96
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
3.8
9.5
39
106
UKC02
NOMESCO Finland
Cystoscopy
1.9
9.5
148
836
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.3
9.5
90
414
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
9.4
162
945
TAB20
NOMESCO Finland
Epidural puncture
7.6
9.4
21
28
NFB50
NOMESCO Finland
Primary total prosthetic replacement of hip joint using cement
30.3
9.4
12
*
M15.4
ICD-10 Finland
Erosive (osteo)arthrosis
30.3
9.4
12
*
M76.9
ICD-10 Finland
Enthesopathy of lower limb, unspecified
6.3
9.4
24
39
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.7
9.4
213
1355
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
9.4
9
*
7188E
ICD-9 Finland
Other derangement of joint, Other joint derangement, not elsewhere classified[MB ARTICULI, LIGAM ET CARTILAG AL DEF,LONKKANIVEL]
+∞
9.4
9
*
XA402
NOMESCO Finland
ENMG
4.5
9.4
32
73
R42
ICD-10 Finland
Dizziness and giddiness
1.6
9.4
238
1563
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
21.9
9.4
13
6
M01AB08
ATC
etodolac; oral
2.4
9.3
76
325
N02AA05
ATC
oxycodone; systemic
1.9
9.3
141
786
M18.9
ICD-10 Finland
Arthrosis of first carpometacarpal joint, unspecified
9.6
9.3
18
19
K07.60
ICD-10 Finland
Snapping jaw
2.8
9.2
58
213
R01AD01
ATC
beclometasone; nasal
1.8
9.2
177
1069
R03BA05
ATC
fluticasone; inhalant
1.7
9.2
189
1165
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.1
9.2
105
527
S91.3
ICD-10 Finland
Open wound of other parts of foot
4.6
9.1
30
66
L60.0
ICD-10 Finland
Ingrowing nail
3.0
9.1
50
170
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
9.1
280
1928
NBG10
NOMESCO Finland
Acromioplastia
4.2
9.0
33
81
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
9.0
198
1246
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.8
8.9
173
1049
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.6
8.9
65
262
73808
ICD-8 Finland
Other deformities, Aliae definitae
18.7
8.9
13
7
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
4.7
8.9
29
63
L01
ICPC
Neck symptom/complaint
1.8
8.9
147
844
B01AX05
ATC
fondaparinux; parenteral
24.2
8.9
12
5
M54.2
ICD-10 Finland
Cervicalgia
2.3
8.9
79
353
NH3BG
NOMESCO Finland
MRI of foot
12.6
8.9
15
12
1225
FHL
Arthroscopy and other therapeutic procedure
12.6
8.9
15
12
R05FA02
ATC
opium derivatives and expectorants; systemic
1.5
8.8
445
3426
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
8.8
128
701
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.8
8.8
55
201
N39.3
ICD-10 Finland
Stress incontinence
2.1
8.8
102
514
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.8
8.8
146
841
E000001
ATC
NA
1.6
8.8
219
1429
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
3.8
8.8
35
93
H03AA01
ATC
levothyroxine sodium; systemic
1.6
8.7
291
2041
R4120
NOMESCO Finland
Occupational therapy
2.6
8.7
63
253
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
8.7
261
1786
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
8.7
185
1154
XG474
NOMESCO Finland
Exhalation nntrogen oxide
3.6
8.7
37
104
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
8.7
180
1114
SPAT1043
SPAT
Audiometry
2.0
8.7
119
639
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.5
8.6
426
3260
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
8.6
80
366
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
8.6
416
3171
M65.3
ICD-10 Finland
Trigger finger
3.0
8.6
49
170
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
10.1
8.5
16
16
M20
ICD-10 Finland
Acquired deformities of fingers and toes
27.7
8.5
11
*
NDG76
NOMESCO Finland
Fusion of DIP joint
27.7
8.5
11
*
A04
ICPC
Weakness/tiredness general
1.8
8.5
147
860
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
5.7
8.5
23
41
NGT60
NOMESCO Finland
Forcible manipulation of knee joint
90.7
8.4
9
*
R01AD12
ATC
fluticasone furoate; nasal
1.5
8.4
301
2148
A99
ICPC
Disease/condition unspecnature/site
2.1
8.4
91
447
N81.6
ICD-10 Finland
Rectocele
2.2
8.4
88
425
M54.6
ICD-10 Finland
Pain in thoracic spine
2.4
8.4
70
303
T84.1
ICD-10 Finland
Mechanical complication of internal fixation device of bones of limb
12.9
8.4
14
11
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.3
8.4
73
324
S29
ICPC
Skin symptom/complaint other
1.7
8.4
182
1143
7352A
ICD-9 Finland
Acquired deformities of toe, Hallux rigidus
+∞
8.3
8
*
M21.5
ICD-10 Finland
Acquired clawhand, clubhand, clawfoot and clubfoot
+∞
8.3
8
*
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
+∞
8.3
8
*
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
+∞
8.3
8
*
A29
ICPC
General symptom/complaint other
1.9
8.3
121
667
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
5.3
8.3
24
46
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.7
8.3
56
215
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
3.2
8.3
42
136
XKD00
NOMESCO Finland
Uroflowmetry
1.9
8.2
116
630
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
8.2
43
142
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.9
8.2
112
602
R03AC13
ATC
formoterol; inhalant
2.6
8.2
56
218
J46
ICD-10 Finland
Status asthmaticus
3.7
8.2
34
94
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
4.7
8.1
26
56
M01AB01
ATC
indometacin; systemic, rectal
2.3
8.1
69
304
9359
FHL
Other measure in this category
33.6
8.1
10
*
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
11.8
8.1
14
12
9243
FHL
Plastic of the patella and its tendons
17.3
8.1
12
7
M25.0
ICD-10 Finland
Haemarthrosis
17.3
8.1
12
7
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
3.9
8.1
31
80
R05
ICD-10 Finland
Cough
1.6
8.1
206
1350
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
8.0
191
1227
L11
ICPC
Wrist symptom/complaint
2.2
8.0
83
398
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
8.0
346
2565
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
8.0
266
1863
S91.1
ICD-10 Finland
Open wound of toe(s) without damage to nail
5.6
8.0
22
40
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
3.0
8.0
44
151
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
8.0
108
579
J01DC02
ATC
cefuroxime; systemic
2.4
8.0
64
271
SPAT1147
SPAT
Destruction of skin lesion with external methods
4.8
8.0
25
53
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.3
7.9
70
312
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
2.8
7.9
48
175
SPAT1254
SPAT
Administration of medicine
1.8
7.9
144
856
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
7.9
206
1357
M35.7
ICD-10 Finland
Hypermobility syndrome
7.8
7.9
17
22
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.7
7.9
32
87
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.8
7.9
128
733
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
7.9
77
361
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
7.8
451
3544
D82
ICPC
Teeth/gum disease
1.5
7.8
346
2579
9255
FHL
Joint auger removal
45.3
7.7
9
*
M75.2
ICD-10 Finland
Bicipital tendinitis
4.1
7.7
28
69
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.0
7.7
94
486
N05BA04
ATC
oxazepam; oral
1.5
7.6
267
1892
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
18.5
7.6
11
6
R03AC03
ATC
terbutaline; inhalant
1.7
7.6
148
899
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.1
7.6
16
20
Z47.0
ICD-10 Finland
Follow-up care involving removal of fracture plate and other internal fixation device
8.1
7.6
16
20
NG1AD
NOMESCO Finland
Knee CT examination
8.1
7.6
16
20
M17.5
ICD-10 Finland
Other secondary gonarthrosis
25.2
7.6
10
*
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
7.6
214
1437
J01MA01
ATC
ofloxacin; systemic
2.1
7.6
87
439
A06AD11
ATC
lactulose; oral
1.7
7.6
149
907
N06AB03
ATC
fluoxetine; oral
1.8
7.6
139
828
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
10.1
7.5
14
14
Z50.1
ICD-10 Finland
Other physical therapy
2.6
7.5
55
221
N05CD07
ATC
temazepam; oral
1.8
7.5
130
759
SPAT1301
SPAT
No procedures
1.5
7.5
330
2453
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.4
7.5
34
102
B35.3
ICD-10 Finland
Tinea pedis
2.9
7.5
43
151
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
2.5
7.5
55
224
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
4.3
7.4
26
62
M06
ICD-10 Finland
Other rheumatoid arthritis
80.6
7.4
8
*
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
6.5
7.4
18
28
Z01.9
ICD-10 Finland
Special examination, unspecified
2.3
7.4
69
316
G57.8
ICD-10 Finland
Other mononeuropathies of lower limb
10.9
7.3
13
12
L04AA11
ATC
[U] etanercept; parenteral
+∞
7.3
7
*
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
3.9
7.3
28
73
R03BA02
ATC
budesonide; inhalant
1.6
7.3
185
1209
M54
ICD-10 Finland
Dorsalgia
1.9
7.3
112
629
R03BA01
ATC
beclometasone; inhalant
1.7
7.3
146
892
R52.2
ICD-10 Finland
Other chronic pain
3.2
7.2
35
110
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.3
7.2
25
59
D07AC13
ATC
mometasone; topical
1.5
7.2
299
2192
M67.0
ICD-10 Finland
Short Achilles tendon (acquired)
15.8
7.2
11
7
9057A
ICD-9 Finland
Late effects of musculoskeletal and connective tissue injuries, Late effect of sprain and strain without mention of tendon injury
15.8
7.2
11
7
R13
ICD-10 Finland
Dysphagia
2.3
7.2
65
293
N81.1
ICD-10 Finland
Cystocele
2.0
7.2
92
482
WX290
NOMESCO Finland
Other blockade of nerve
1.4
7.2
426
3351
M13.0
ICD-10 Finland
Polyarthritis, unspecified
30.2
7.2
9
*
L40.5
ICD-10 Finland
Arthropathic psoriasis
20.1
7.1
10
5
M05BA04
ATC
alendronic acid; oral
1.9
7.1
100
545
KMAK
NOMESCO Finland
NA
1.4
7.1
535
4390
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
5.1
7.1
21
42
R06.5
ICD-10 Finland
Mouth breathing
2.1
7.1
77
379
R05FB02
ATC
cough suppressants and expectorants
1.4
7.1
409
3200
A98
ICPC
Health maint/preventive medicine
1.9
7.1
1144
10888
ZA1.0
ICD-10 Finland
Shoulder region
3.9
7.1
27
70
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.9
7.1
95
507
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
4.4
7.0
24
56
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.4
7.0
602
5049
L91
ICPC
Osteoarthrosis other
4.7
7.0
22
47
M70.7
ICD-10 Finland
Other bursitis of hip
3.5
7.0
31
91
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.5
7.0
259
1851
S83.5
ICD-10 Finland
Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
3.6
7.0
30
86
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.0
7.0
87
453
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.2
7.0
66
304
G56.2
ICD-10 Finland
Lesion of ulnar nerve
3.4
6.9
31
92
R03DA04
ATC
theophylline; systemic, rectal
2.4
6.9
53
223
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
6.9
32
98
C03CA01
ATC
furosemide; systemic
1.5
6.9
252
1800
L02
ICPC
Back symptom/complaint
2.0
6.9
88
464
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.7
6.8
134
815
M89.0
ICD-10 Finland
Algoneurodystrophy
9.4
6.8
13
14
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.8
306
2281
7000A
ICD-9 Finland
Corns and callosities[CLAVUS ET CALLOSITAS]
40.3
6.8
8
*
S06.0
ICD-10 Finland
Concussion
1.9
6.8
99
549
NHE20
NOMESCO Finland
Plastic repair of capsule or ligament of ankle joint with transplant
16.8
6.7
10
6
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
4.3
6.7
23
54
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.9
6.7
37
128
9165
FHL
Removal of osteosynthesis material
4.1
6.7
24
59
QDH00
NOMESCO Finland
Avulsion of toe nail
22.6
6.7
9
*
M04AA01
ATC
allopurinol; systemic
1.9
6.7
90
481
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.3
6.7
57
253
J20
ICD-10 Finland
Acute bronchitis
1.8
6.7
105
593
B01AE07
ATC
dabigatran etexilate; oral
2.9
6.7
38
132
J45
ICD-10 Finland
Asthma
1.8
6.7
105
594
A03FA02
ATC
cisapride; oral, rectal
1.9
6.7
88
468
M02AA15
ATC
diclofenac; topical (antiinflammatory prep., non-steroids for topical use)
2.0
6.6
80
412
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.6
6.6
197
1339
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.1
6.6
75
375
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
6.6
75
375
WX213
NOMESCO Finland
Lower leg blockade
12.3
6.6
11
9
Z30.2
ICD-10 Finland
Sterilization
1.8
6.5
106
606
M76.0
ICD-10 Finland
Gluteal tendinitis
4.2
6.5
23
56
G04CA02
ATC
tamsulosin; oral
1.7
6.5
131
804
B07.9
ICD-10 Finland
Verruca simplex
2.9
6.5
37
129
A03CA02
ATC
clidinium and psycholeptics; oral
2.1
6.5
70
345
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.4
6.5
376
2936
D02AE01
ATC
carbamide; topical
2.1
6.4
68
333
NF1AT
NOMESCO Finland
Puncture of hip joint with ultrasound guidance
70.2
6.4
7
*
NGB30
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part - connected prosthesis
70.2
6.4
7
*
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
70.2
6.4
7
*
S17
ICPC
Abrasion/scratch/blister
3.6
6.4
27
77
A06AC51
ATC
ispaghula, combinations; systemic
2.2
6.4
62
290
F45.8
ICD-10 Finland
Other somatoform disorders
2.1
6.4
67
326
E883A
ICD-9 Finland
Fall into hole or other opening in surface
2.5
6.4
48
198
M41.9
ICD-10 Finland
Scoliosis, unspecified
4.4
6.4
21
48
A03
ICPC
Fever
1.7
6.3
141
890
J01EA01
ATC
trimethoprim; systemic
1.4
6.3
288
2145
M67.8
ICD-10 Finland
Other specified disorders of synovium and tendon
8.2
6.3
13
16
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.1
6.3
67
328
J01CF02
ATC
cloxacillin; systemic
3.6
6.3
26
73
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
2.0
6.3
75
383
XF402
NOMESCO Finland
ECG with work load test
1.8
6.3
109
638
H02
ICPC
Hearing complaint
1.7
6.3
126
773
Y79.2
ICD-10 Finland
Orthopaedic devices associated with adverse incidents, prosthetic and other implants, materials and accessory devices
+∞
6.3
6
*
NDF60
NOMESCO Finland
Operation for osteochondritis of a joint of hand,v
+∞
6.3
6
*
7340A
ICD-9 Finland
Flat foot[PES PLANUS]
+∞
6.3
6
*
NK5BT
NOMESCO Finland
Joint injection with X-ray guidance not elsewhere classified
+∞
6.3
6
*
7151D
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, KÄSI]
+∞
6.3
6
*
NDG79
NOMESCO Finland
Other excision, reconstruction or fusion of joint of II-V finger
+∞
6.3
6
*
NDB60
NOMESCO Finland
Prosthetic replacement of MCP joint of finger
+∞
6.3
6
*
E03
ICD-10 Finland
Other hypothyroidism
2.0
6.2
79
415
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
3.0
6.2
33
112
9531
FHL
Arthrodesis of the hand joint
26.8
6.2
8
*
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
26.8
6.2
8
*
NG1EA
NOMESCO Finland
Knee X-ray examination with wrench
26.8
6.2
8
*
L20
ICPC
Joint symptom/complaint NOS
2.9
6.2
34
118
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.9
6.2
34
118
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
6.2
117
704
P06
ICPC
Sleep disturbance
1.9
6.2
92
512
M35.3
ICD-10 Finland
Polymyalgia rheumatica
2.7
6.2
40
152
SPAT1260
SPAT
Consultation of another employee
1.6
6.2
181
1228
N04BC05
ATC
pramipexole; oral
2.0
6.1
74
381
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
6.1
94
530
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
4.3
6.1
21
50
R15
ICD-10 Finland
Faecal incontinence
2.8
6.1
36
130
S89.9
ICD-10 Finland
Unspecified injury of lower leg
3.1
6.1
30
97
P20
ICPC
Memory disturbance
1.7
6.1
119
721
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
12.6
6.1
10
8
NBE45
NOMESCO Finland
Plastic repair of ligament of shoulder not using prosthetic material, arthroscopic
12.6
6.1
10
8
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
3.4
6.1
27
81
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
3.4
6.1
27
81
W22
ICD-10 Finland
Striking against or struck by other object(s)
2.3
6.1
52
230
G03FB06
ATC
medroxyprogesterone and estrogen; systemic (progestogens and estrogens, sequential prep.)
1.7
6.1
127
787
SPAT1234
SPAT
Support of social functional capacity
2.3
6.1
50
219
N06AX16
ATC
venlafaxine; oral
1.7
6.0
130
812
R06AX13
ATC
loratadine; oral
1.6
6.0
159
1048
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
4.2
6.0
21
51
NGE35
NOMESCO Finland
Plastic repair of ligament of knee not using prosthetic material, anterior cruciate, arthroscopic
4.2
6.0
21
51
J37.0
ICD-10 Finland
Chronic laryngitis
2.8
6.0
36
132
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
6.0
480
3946
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
6.0
65
322

Mortality – FinRegistry

Association

Association between endpoint M13_TOEDEFORMOTH and mortality.

Females

Parameter HR [95% CI] p-value
M13_TOEDEFORMOTH 0.927 [0.82, 1.05] 0.218
Birth year 0.994 [0.99, 1.0] 0.201

During the follow-up period (1.1.1998 — 31.12.2019), 452 out of 3987 females with M13_TOEDEFORMOTH died.

Males

Parameter HR [95% CI] p-value
M13_TOEDEFORMOTH 1.03 [0.88, 1.21] 0.72
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 236 out of 1474 males with M13_TOEDEFORMOTH died.

Mortality risk

Mortality risk for people of age

years, who have M13_TOEDEFORMOTH.

N-year risk Females Males
1 0.079% 0.15%
5 0.548% 1.001%
10 1.352% 2.461%
15 2.691% 4.761%
20 4.628% 8.131%

Relationships between endpoints

Index endpoint: M13_TOEDEFORMOTH – Other deformities of toe(s)

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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