Chondrocostal junction syndrome [Tietze]

M13_TIETZE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M94.0
  • Hospital discharge: ICD-9 7336
  • Cause of death: ICD-10 M94.0
  • Cause of death: ICD-9 7336

2 out of 7 registries used, show all original rules.

1375

4. Check minimum number of events

None

1375

5. Include endpoints

None

1375

6. Filter based on genotype QC (FinnGen only)

1375

Control definitions (FinnGen only)

Control exclude
M13_OTHERBONE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M94
Name in latin
Morbus Tietze

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9755 6794 2871
Only index persons 9164 6431 2733
Unadjusted period prevalence (%)
Whole population 0.16 0.19 0.08
Only index persons 0.20 0.24 0.10
Median age at first event (years)
Whole population 53.16 56.14 46.65
Only index persons 52.20 54.94 45.75

-FinnGen-

Key figures

All Female Male
Number of individuals 1375 1039 336
Unadjusted period prevalence (%) 0.30 0.35 0.15
Median age at first event (years) 54.95 54.66 55.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1207
Matched controls
12070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
4657.8
323.0
1167
75
R07.4
ICD-10 Finland
Chest pain, unspecified
6.6
193.0
682
1974
R07.3
ICD-10 Finland
Other chest pain
7.0
113.3
314
578
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.7
99.9
674
3054
R10.1
ICD-10 Finland
Pain localized to upper abdomen
4.2
81.4
375
1174
R51.80
ICD-10 Finland
Headache
4.1
75.6
347
1072
A02BC02
ATC
pantoprazole; systemic
3.3
74.4
921
5950
M79.6
ICD-10 Finland
Pain in limb
3.0
69.3
597
2954
G44.2
ICD-10 Finland
Tension-type headache
3.7
55.9
285
933
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
53.7
624
3519
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.9
52.5
401
1753
R06.0
ICD-10 Finland
Dyspnoea
2.9
52.4
412
1834
N02AX02
ATC
tramadol; systemic, rectal
2.6
52.0
612
3452
N03AX16
ATC
pregabalin; oral
2.9
51.5
393
1712
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
51.4
451
2141
R42
ICD-10 Finland
Dizziness and giddiness
2.9
51.1
380
1626
A02BC05
ATC
esomeprazole; systemic
2.5
49.4
600
3412
M54.6
ICD-10 Finland
Pain in thoracic spine
4.9
48.8
173
399
A11
ICPC
Chest pain NOS
4.5
45.8
178
450
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.0
44.6
302
1198
M54.5
ICD-10 Finland
Low back pain
2.5
44.1
507
2744
7336A
ICD-9 Finland
Other disorders of bone and cartilage, Tietze's disease
+∞
44.0
42
*
R52.9
ICD-10 Finland
Pain, unspecified
4.1
42.6
180
492
M25.5
ICD-10 Finland
Pain in joint
2.5
41.4
434
2217
R03AC02
ATC
salbutamol; inhalant
2.3
39.8
723
4813
D01
ICPC
Abdominal pain/cramps general
3.4
39.7
218
738
N02BE01
ATC
paracetamol; systemic, rectal
3.2
39.5
1089
8982
N03AX12
ATC
gabapentin; oral
3.0
39.4
261
1011
R53
ICD-10 Finland
Malaise and fatigue
2.6
39.3
342
1567
K30
ICD-10 Finland
Functional dyspepsia
3.5
39.2
207
680
XF400
NOMESCO Finland
ECG with 12 standard connections
2.9
38.6
269
1075
L04
ICPC
Chest symptom/complaint
4.4
36.1
140
350
M54.4
ICD-10 Finland
Lumbago with sciatica
2.8
36.1
271
1131
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.6
35.7
303
1357
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.2
35.4
613
3903
AA1AD
NOMESCO Finland
CT of head and brain
2.5
34.8
345
1680
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.7
34.6
282
1232
M03BX02
ATC
tizanidine; oral
2.1
33.9
802
5800
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.1
33.6
205
742
M01AH05
ATC
etoricoxib; oral
2.1
33.3
751
5298
M79.1
ICD-10 Finland
Myalgia
2.9
33.1
229
900
R07.2
ICD-10 Finland
Precordial pain
10.2
32.9
66
68
H02AB06
ATC
prednisolone; systemic
2.1
32.8
618
4033
N02AJ06
ATC
codeine and paracetamol; systemic
2.1
32.6
507
3044
A02BC03
ATC
lansoprazole; oral
2.3
32.6
410
2239
A02BC01
ATC
omeprazole; systemic
2.3
32.5
399
2152
M01AB05
ATC
diclofenac; systemic, rectal
2.1
32.2
839
6246
M03BC01
ATC
orphenadrine (citrate); systemic
2.4
32.1
351
1789
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.3
32.0
176
590
A01
ICPC
Pain general/multiple sites
3.6
31.7
152
459
P01AB01
ATC
metronidazole; oral, rectal
2.1
31.0
549
3462
J45.9
ICD-10 Finland
Asthma, unspecified
2.5
30.5
280
1295
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.3
30.1
333
1698
R02
ICPC
Shortness of breath/dyspnoea
2.9
29.4
202
787
L03
ICPC
Low back symptom/complaint
2.2
29.4
360
1923
A02BA02
ATC
ranitidine; systemic
2.4
28.8
290
1402
N01
ICPC
Headache
2.9
28.7
198
772
R00.2
ICD-10 Finland
Palpitations
3.6
28.3
139
426
N06AX21
ATC
duloxetine; oral
2.9
27.9
184
697
J01AA02
ATC
doxycycline; systemic
2.2
27.6
957
7724
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
27.4
204
833
L01
ICPC
Neck symptom/complaint
2.6
27.3
224
969
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.5
27.3
252
1164
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
26.8
591
3983
UJF32
NOMESCO Finland
Coloscopy
2.2
26.8
343
1853
Z71.8
ICD-10 Finland
Other specified counselling
2.2
26.6
349
1905
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
26.4
399
2314
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.7
25.4
89
200
I20.09
ICD-10 Finland
Unstable angina
4.3
25.4
97
238
R51
ICD-10 Finland
Headache
3.8
24.4
107
298
R20.2
ICD-10 Finland
Paraesthesia of skin
3.4
24.4
126
401
M79.7
ICD-10 Finland
Fibromyalgia
4.9
24.2
82
178
G43.9
ICD-10 Finland
Migraine, unspecified
3.5
24.1
117
355
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.9
24.1
159
601
D06
ICPC
Abdominal pain localized other
3.0
24.0
151
553
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.7
23.9
184
761
R74
ICPC
Upper respiratory infection acute
2.0
23.9
397
2371
A04
ICPC
Weakness/tiredness general
2.5
23.8
203
892
J01DB01
ATC
cefalexin; oral
2.1
23.7
1001
8390
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
23.6
282
1465
C07AB07
ATC
bisoprolol; oral
1.9
23.6
557
3786
D02
ICPC
Abdominal pain epigastric
3.6
23.4
111
330
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.8
23.2
671
4879
J01FA06
ATC
roxithromycin; oral
1.9
23.2
515
3417
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.5
23.1
194
844
M01AE02
ATC
naproxen; oral, rectal
1.8
22.6
720
5383
XF600
NOMESCO Finland
Bloodpressure measurement
3.5
22.6
110
334
N30.0
ICD-10 Finland
Acute cystitis
2.3
22.5
227
1088
A02BC04
ATC
rabeprazole; oral
2.9
22.3
148
558
M01AH02
ATC
rofecoxib; oral
2.5
21.9
195
876
XF402
NOMESCO Finland
ECG with work load test
2.7
21.8
163
664
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
21.7
249
1263
M54.2
ICD-10 Finland
Cervicalgia
3.2
21.7
121
406
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.2
21.6
249
1270
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
21.5
223
1080
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.7
21.5
164
675
R07.0
ICD-10 Finland
Pain in throat
3.3
21.4
113
365
M03BC51
ATC
orphenadrine, combinations; systemic
2.0
21.3
369
2220
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
21.2
337
1962
C01DA14
ATC
isosorbide mononitrate; oral
2.5
21.0
187
837
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
21.0
288
1577
R11
ICD-10 Finland
Nausea and vomiting
2.8
20.7
141
542
M02AA07
ATC
piroxicam; topical
1.8
20.4
459
3022
N05BA04
ATC
oxazepam; oral
2.0
20.3
335
1975
C07AA05
ATC
propranolol; systemic
2.1
20.2
272
1476
R05
ICPC
Cough
2.0
20.0
304
1734
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
20.0
370
2270
M01AE03
ATC
ketoprofen; systemic, rectal
1.8
19.8
453
2991
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.1
19.8
254
1349
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.8
19.7
138
538
R03BA02
ATC
budesonide; inhalant
2.1
19.6
245
1287
SPAT1263
SPAT
Sampling
1.8
19.5
540
3787
M01AH01
ATC
celecoxib; oral (coxibs)
2.1
19.5
248
1312
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
19.4
592
4276
R12
ICD-10 Finland
Heartburn
3.0
19.3
116
411
J01MA02
ATC
ciprofloxacin; systemic
1.8
19.2
460
3075
R21
ICPC
Throat symptom/complaint
2.0
19.2
287
1621
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.6
19.1
153
644
S06.0
ICD-10 Finland
Concussion
2.5
19.1
162
707
WX110
NOMESCO Finland
Local anesthesy
1.8
19.0
834
6720
N17
ICPC
Vertigo/dizziness
2.5
19.0
166
734
M70.6
ICD-10 Finland
Trochanteric bursitis
2.4
18.9
183
852
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.4
18.9
96
302
R52.2
ICD-10 Finland
Other chronic pain
4.3
18.7
71
174
H02AB07
ATC
prednisone; oral
2.3
18.7
200
978
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
18.6
616
4540
C08CA01
ATC
amlodipine; oral
1.8
18.6
401
2584
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
18.6
134
530
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
18.5
845
6859
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
18.4
368
2308
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.3
18.4
189
905
Z3231
NOMESCO Finland
Registered nurse
1.9
18.3
351
2169
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.4
18.3
162
722
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.9
18.0
112
406
L17
ICPC
Foot/toe symptom/complaint
1.9
17.8
318
1911
Z3226
NOMESCO Finland
Physiotherapist
2.0
17.8
246
1344
Z2221
NOMESCO Finland
Medical doctor
1.8
17.8
367
2321
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.9
17.8
58
122
R06AE07
ATC
cetirizine; oral
1.7
17.7
566
4103
L02
ICPC
Back symptom/complaint
2.6
17.7
142
598
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
17.7
146
626
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
17.7
204
1030
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
17.7
507
3562
M01AC06
ATC
meloxicam; systemic, rectal
1.8
17.6
444
2995
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.1
17.5
221
1160
N05CF01
ATC
zopiclone; oral
1.8
17.3
392
2553
UJF30
NOMESCO Finland
Ileoscopy through colon
2.6
17.3
136
567
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
4.0
17.2
69
178
L05
ICPC
Flank/axilla symptom/complaint
3.3
17.2
91
295
C10AA05
ATC
atorvastatin; oral
1.8
17.1
415
2760
J01FF01
ATC
clindamycin; systemic
1.9
17.1
325
1995
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
17.1
200
1017
XF404
NOMESCO Finland
Ambulatory ECG
2.6
17.0
126
509
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.9
17.0
289
1704
R4110
NOMESCO Finland
Physiotherapy
1.8
16.9
328
2026
R09.1
ICD-10 Finland
Pleurisy
6.6
16.8
43
67
R05
ICD-10 Finland
Cough
2.0
16.8
251
1409
R13
ICD-10 Finland
Dysphagia
3.0
16.8
100
350
SPAT1097
SPAT
Recording of ECG
2.2
16.8
188
937
R03AK07
ATC
formoterol and budesonide; inhalant
2.0
16.7
249
1397
UKC02
NOMESCO Finland
Cystoscopy
2.2
16.6
176
855
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
16.5
134
567
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.6
16.4
123
500
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.1
16.4
94
323
N06AA09
ATC
amitriptyline; systemic
2.4
16.3
145
646
N05AH04
ATC
quetiapine; oral
2.1
16.3
218
1170
M89.0
ICD-10 Finland
Algoneurodystrophy
48.2
16.0
19
*
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.5
16.0
75
222
K59.09
ICD-10 Finland
Constipation, unspecified
3.0
15.9
96
341
M54.8
ICD-10 Finland
Other dorsalgia
3.7
15.9
71
202
R35
ICD-10 Finland
Polyuria
3.2
15.9
87
290
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
15.8
275
1632
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.9
15.8
270
1592
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.6
15.6
120
491
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.4
15.6
140
624
B01AB05
ATC
enoxaparin; parenteral
1.8
15.6
349
2250
J01CA04
ATC
amoxicillin; systemic
1.8
15.6
976
8447
N06AX11
ATC
mirtazapine; oral
1.7
15.5
389
2597
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.4
15.5
75
228
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
15.3
173
861
R03BA05
ATC
fluticasone; inhalant
1.9
15.3
243
1392
S29
ICPC
Skin symptom/complaint other
2.0
15.2
214
1171
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.2
15.0
81
267
R51.81
ICD-10 Finland
Facial pain NOS
4.7
15.0
51
113
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.4
14.9
128
559
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.7
14.7
103
403
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.0
14.7
205
1118
D11
ICPC
Diarrhoea
2.2
14.6
160
786
AN1
HP
Coronary angiography
2.4
14.6
129
572
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
14.6
222
1249
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.4
14.6
124
540
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
14.6
172
872
N06AX16
ATC
venlafaxine; oral
2.1
14.5
184
963
Z01.2
ICD-10 Finland
Dental examination
1.6
14.5
500
3638
R03DC03
ATC
montelukast; oral
2.0
14.4
212
1177
N03AE01
ATC
clonazepam; systemic
2.9
14.4
91
332
WX002
NOMESCO Finland
Sedation and analgesia
1.9
14.3
237
1378
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
3.1
14.3
78
260
R50.9
ICD-10 Finland
Fever, unspecified
2.1
14.3
178
924
R07.1
ICD-10 Finland
Chest pain on breathing
6.6
14.2
36
56
R55
ICD-10 Finland
Syncope and collapse
2.3
14.2
136
628
K02.1
ICD-10 Finland
Caries of dentine
1.6
14.1
659
5170
N05BA01
ATC
diazepam; systemic, rectal
2.1
14.1
171
880
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
14.0
454
3237
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
5.3
14.0
42
81
G47.3
ICD-10 Finland
Sleep apnoea
1.9
14.0
224
1283
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.4
14.0
68
208
J01DA01
ATC
[U] cefalexin; systemic
1.6
13.9
739
5985
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.7
13.9
357
2383
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.0
13.8
185
990
Z2446
NOMESCO Finland
Social worker
2.7
13.7
99
393
M01AE01
ATC
ibuprofen; systemic, rectal
1.9
13.6
1065
9594
N02AA05
ATC
oxycodone; systemic
2.1
13.6
168
869
L86
ICPC
Back syndrome with radiating pain
2.8
13.6
88
328
L15
ICPC
Knee symptom/complaint
1.8
13.6
257
1560
M75.8
ICD-10 Finland
Other shoulder lesions
3.5
13.6
63
186
H92.0
ICD-10 Finland
Otalgia
2.9
13.5
86
316
ZXE00
NOMESCO Finland
One hour or less
1.6
13.4
464
3359
R03AC03
ATC
terbutaline; inhalant
2.0
13.3
179
957
SPAT1211
SPAT
Application of soft bandage
2.3
13.3
128
592
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.4
13.2
120
539
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.5
13.2
109
467
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.7
13.2
90
347
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.8
13.1
85
316
SPAT1254
SPAT
Administration of medicine
2.0
13.0
192
1062
J01FA09
ATC
clarithromycin; systemic
1.7
13.0
382
2638
J01EA01
ATC
trimethoprim; systemic
1.7
12.9
337
2254
L28
ICPC
Limited function/disability (L)
1.9
12.9
191
1062
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.6
12.8
650
5157
R01AD12
ATC
fluticasone furoate; nasal
1.7
12.8
357
2434
N64.4
ICD-10 Finland
Mastodynia
4.0
12.7
50
128
R01AD08
ATC
fluticasone; nasal
1.7
12.7
344
2321
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.8
12.7
80
294
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
12.7
133
640
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.6
12.6
617
4845
N05BA12
ATC
alprazolam; oral
2.2
12.6
137
671
R5599
NOMESCO Finland
Other rehabilitation service
4.0
12.5
49
125
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.4
12.5
110
485
SPAT1260
SPAT
Consultation of another employee
1.8
12.5
221
1305
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.2
12.4
127
603
U07
ICPC
Urine symptom/complaint other
2.8
12.4
82
310
G50.1
ICD-10 Finland
Atypical facial pain
5.0
12.4
39
80
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
12.4
176
960
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
12.4
756
6242
F29
ICPC
Eye symptom/complaint other
2.3
12.4
115
524
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.0
12.3
168
902
R04.2
ICD-10 Finland
Haemoptysis
4.3
12.3
45
108
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
12.3
162
858
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
12.3
232
1402
WX892
NOMESCO Finland
Monitored bed care
2.5
12.3
97
405
N06AB04
ATC
citalopram; systemic
1.7
12.3
266
1679
M01AX17
ATC
nimesulide; oral
1.7
12.2
279
1792
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
12.2
415
2974
R60.0
ICD-10 Finland
Localized oedema
2.2
12.1
136
672
M02AA10
ATC
ketoprofen; topical
1.9
12.1
194
1110
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.3
11.8
113
519
X58
ICD-10 Finland
Exposure to other specified factors
2.0
11.8
168
917
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.2
11.8
127
617
S22.3
ICD-10 Finland
Fracture of rib
2.7
11.8
81
313
J02AC01
ATC
fluconazole; systemic
1.6
11.8
508
3849
R01AD09
ATC
mometasone; nasal
1.5
11.7
527
4029
T78.4
ICD-10 Finland
Allergy, unspecified
2.9
11.7
73
266
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.9
11.7
69
243
K08.80
ICD-10 Finland
Toothache NOS
2.4
11.7
103
457
Z00.8
ICD-10 Finland
Other general examinations
2.5
11.7
96
409
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.3
11.6
107
484
L18
ICPC
Muscle pain
3.4
11.6
56
171
ZXA00
NOMESCO Finland
Right side
1.7
11.6
305
2033
P01
ICPC
Feeling anxious/nervous/tense
2.0
11.6
147
767
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
11.5
124
605
H02AB04
ATC
methylprednisolone; systemic
1.9
11.5
182
1034
XQ800
NOMESCO Finland
Prick test
2.4
11.5
103
458
S18
ICPC
Laceration/cut
1.6
11.4
440
3240
W10
ICD-10 Finland
Fall on and from stairs and steps
2.8
11.4
74
275
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.9
11.4
68
242
XKD00
NOMESCO Finland
Uroflowmetry
2.1
11.3
130
651
M54
ICD-10 Finland
Dorsalgia
2.0
11.3
151
807
L12
ICPC
Hand/finger symptom/complaint
1.9
11.3
173
972
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.7
11.2
77
296
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.5
11.2
90
379
R96
ICPC
Asthma
2.2
11.2
116
555
SPAT1240
SPAT
Therapeutic discussion
2.0
11.1
146
773
K04
ICPC
Palpitations/awareness of heart
2.8
11.1
73
274
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.2
11.1
109
511
H53.1
ICD-10 Finland
Subjective visual disturbances
2.5
11.0
89
376
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
5.0
11.0
34
69
R03BA08
ATC
ciclesonide; inhalant
2.3
10.9
107
497
K59.0
ICD-10 Finland
Constipation
2.6
10.9
79
314
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.3
10.9
100
452
L08
ICPC
Shoulder symptom/complaint
1.8
10.9
219
1347
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
10.9
482
3652
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.7
10.9
271
1777
M13.9
ICD-10 Finland
Arthritis, unspecified
2.4
10.8
95
421
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
10.8
471
3552
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
4.3
10.8
39
93
H57.1
ICD-10 Finland
Ocular pain
3.3
10.8
53
165
ZXD05
NOMESCO Finland
Urgent procedure
1.6
10.8
353
2488
R06AX27
ATC
desloratadine; oral
1.6
10.7
320
2202
K10.3
ICD-10 Finland
Alveolitis of jaws
2.8
10.7
67
245
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.3
10.7
98
442
K02
ICPC
Pressure/tightness of heart
4.1
10.7
40
99
J01CA08
ATC
pivmecillinam; oral
1.5
10.7
538
4194
I20.00
ICD-10 Finland
Unstable angina
3.8
10.5
43
115
SPAT1312
SPAT
General health counselling
1.6
10.5
391
2839
J45.1
ICD-10 Finland
Nonallergic asthma
2.3
10.5
95
428
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
10.4
252
1636
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
2.1
10.3
126
648
A06AD11
ATC
lactulose; oral
1.9
10.3
160
899
K07.60
ICD-10 Finland
Snapping jaw
2.6
10.2
72
283
XX1XW
NOMESCO Finland
Extensive written report from radiologist
4.3
10.2
37
89
M54.3
ICD-10 Finland
Sciatica
2.5
10.2
78
321
P06
ICPC
Sleep disturbance
2.1
10.1
120
608
C10AX09
ATC
ezetimibe; oral
2.1
10.1
114
567
I20.90
ICD-10 Finland
Angina pectoris, unspecified
3.2
10.1
53
173
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
10.1
95
435
7865A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Chest pain
4.9
10.1
32
67
R03BB04
ATC
tiotropium bromide; inhalant
2.2
10.1
104
495
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
10.1
444
3346
SPAT1301
SPAT
No procedures
1.6
10.0
361
2593
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
10.0
592
4751
R06.4
ICD-10 Finland
Hyperventilation
4.5
10.0
34
77
K59.1
ICD-10 Finland
Functional diarrhoea
2.6
9.9
74
301
A03FA02
ATC
cisapride; oral, rectal
2.2
9.9
101
480
D10
ICPC
Vomiting
2.4
9.9
83
359
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.3
9.9
94
433
K74
ICPC
Ischaemic heart dis with angina
6.8
9.9
24
36
D07AC01
ATC
betamethasone; topical
1.5
9.9
378
2753
KMAK
NOMESCO Finland
NA
1.5
9.8
578
4627
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
4.9
9.8
31
65
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.7
9.8
65
246
R05FB02
ATC
cough suppressants and expectorants
1.5
9.7
416
3109
N05AX08
ATC
risperidone; systemic
2.2
9.7
95
444
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.4
9.7
81
349
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
9.7
300
2075
M54.1
ICD-10 Finland
Radiculopathy
3.0
9.7
56
195
J01MA12
ATC
levofloxacin; systemic
1.7
9.7
202
1254
J01FA10
ATC
azithromycin; systemic
1.5
9.7
687
5707
K01
ICPC
Heart pain
5.9
9.7
26
45
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.8
9.7
60
218
G54.0
ICD-10 Finland
Brachial plexus disorders
3.8
9.7
39
104
K80
ICPC
Cardiac arrhythmia NOS
2.3
9.5
91
420
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
9.5
373
2727
L14
ICPC
Leg/thigh symptom/complaint
2.3
9.5
91
421
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
9.5
455
3479
M01AX01
ATC
nabumetone; oral
2.7
9.5
63
238
SPAT1216
SPAT
Assessment of functional ability
1.8
9.4
172
1022
C07AB02
ATC
metoprolol; systemic
1.7
9.4
222
1425
KH1AD
NOMESCO Finland
CT of urinary organs
3.5
9.4
42
122
I49.1
ICD-10 Finland
Atrial premature depolarization
3.3
9.3
45
139
S80.0
ICD-10 Finland
Contusion of knee
2.4
9.3
81
356
L29
ICPC
Musculoskeletal sympt/complt other
2.2
9.3
99
481
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.3
9.3
87
399
B01AA03
ATC
warfarin; systemic
1.7
9.3
190
1171
TKC20
NOMESCO Finland
Catheterisation of bladder
2.3
9.2
81
359
W19
ICD-10 Finland
Unspecified fall
2.0
9.2
117
611
N06AB03
ATC
fluoxetine; oral
1.8
9.1
151
870
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
9.1
365
2675
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
2.5
9.1
71
295
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
9.1
157
916
G43.3
ICD-10 Finland
Complicated migraine
4.8
9.1
29
62
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.4
9.1
77
336
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.1
9.0
97
473
Z00.0
ICD-10 Finland
General medical examination
1.7
9.0
211
1353
H01
ICPC
Ear pain/earache
1.9
9.0
137
766
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.9
9.0
128
700
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
2.9
9.0
52
182
A02BA04
ATC
nizatidine; systemic
2.2
9.0
92
439
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.2
8.9
85
393
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.7
8.9
60
229
PD5BD
NOMESCO Finland
Extensive CT of aorta
4.7
8.9
29
63
B01AC04
ATC
clopidogrel; oral
1.8
8.9
147
843
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
8.9
149
863
UJD02
NOMESCO Finland
Gastroscopy
2.6
8.8
61
239
R06AX22
ATC
ebastine; oral
1.7
8.8
197
1245
U02
ICPC
Urinary frequency/urgency
1.8
8.8
173
1051
J20
ICD-10 Finland
Acute bronchitis
2.0
8.8
116
613
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
8.8
168
1016
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.6
8.7
63
252
R33
ICD-10 Finland
Retention of urine
2.4
8.7
72
309
A07EC01
ATC
sulfasalazine; oral, rectal
2.1
8.7
99
493
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.3
8.7
81
371
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.6
8.7
62
246
J05AB01
ATC
aciclovir; systemic
1.6
8.6
242
1627
J45
ICD-10 Finland
Asthma
1.9
8.6
125
689
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.2
8.5
82
381
C10AA07
ATC
rosuvastatin; oral
1.6
8.5
234
1565
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
4.2
8.5
31
76
R75
ICPC
Sinusitis acute/chronic
2.6
8.5
61
243
J31.0
ICD-10 Finland
Chronic rhinitis
2.1
8.5
93
457
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
8.5
235
1576
N30.9
ICD-10 Finland
Cystitis, unspecified
2.2
8.5
82
383
N03AF01
ATC
carbamazepine; oral, rectal
2.5
8.5
64
262
M79.9
ICD-10 Finland
Soft tissue disorder, unspecified
7.4
8.5
19
26
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.2
8.4
83
388
EBA00
NOMESCO Finland
Extraction of tooth
1.5
8.4
353
2609
L13
ICPC
Hip symptom/complaint
1.7
8.4
173
1069
C09AA05
ATC
ramipril; oral
1.6
8.4
237
1596
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.6
8.4
61
246
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.2
8.4
83
391
SPAT1310
SPAT
Counselling related to known health issue
1.5
8.4
366
2731
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
8.3
276
1930
A29
ICPC
General symptom/complaint other
1.9
8.3
126
703
N30
ICD-10 Finland
Cystitis
2.0
8.3
101
520
A03
ICPC
Fever
1.7
8.3
184
1160
-1
NOMESCO Finland
NA
1.5
8.2
378
2846
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
8.2
134
769
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.7
8.2
197
1272
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.2
8.2
86
414
K04.1
ICD-10 Finland
Necrosis of pulp
1.9
8.1
113
609
A07AA02
ATC
nystatin; oral
2.2
8.1
79
369
F41.09
ICD-10 Finland
UNS Panic Syndrome
3.0
8.1
44
149
S21
ICPC
Skin texture symptom/complaint
1.8
8.1
142
832
N76.0
ICD-10 Finland
Acute vaginitis
2.3
8.1
76
348
F01
ICPC
Eye pain
3.1
8.1
42
138
A99
ICPC
Disease/condition unspecnature/site
2.0
8.1
95
483
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.8
8.1
131
748
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
8.0
81
385
4111X
ICD-9 Finland
Other acute and subacute forms of ischaemic heart disease, Intermediate coronary syndrome[PITKITTYNYT ANGINA PECTORIS -KOHTAUS,MÄÄRITTELEMÄT]
10.1
8.0
15
15
R52.0
ICD-10 Finland
Acute pain
2.9
8.0
46
160
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.7
8.0
52
197
R03BA01
ATC
beclometasone; inhalant
1.7
8.0
158
963
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.6
8.0
58
233
R10.0
ICD-10 Finland
Acute abdomen
2.9
8.0
47
168
C09CA06
ATC
candesartan; oral
1.6
8.0
231
1564
SPAT1283
SPAT
Restricted health certificate
1.6
7.9
211
1399
K03.80
ICD-10 Finland
Irradiated enamel
2.5
7.9
61
253
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.5
7.9
294
2111
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.7
7.9
52
199
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
7.9
358
2685
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.9
7.9
46
163
M01AB55
ATC
diclofenac, combinations; oral
2.1
7.9
84
408
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
7.9
197
1286
XG460
NOMESCO Finland
Short time oxymetry
5.4
7.8
22
41
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
7.8
136
794
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.0
7.8
103
547
E0000UV
ATC
NA
1.4
7.8
443
3472
WX290
NOMESCO Finland
Other blockade of nerve
1.4
7.8
486
3879
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
7.7
179
1140
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
7.7
275
1954
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.4
7.7
398
3057
M94.9
ICD-10 Finland
Disorder of cartilage, unspecified
45.3
7.7
9
*
K85
ICPC
Elevated blood pressure
1.7
7.7
155
949
N89
ICPC
Migraine
2.9
7.7
45
160
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
7.7
155
952
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
7.7
783
6826
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
3.1
7.7
39
127
M35.7
ICD-10 Finland
Hypermobility syndrome
4.8
7.6
24
51
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
4.8
7.6
24
51
A97
ICPC
No disease
1.7
7.6
166
1041
B02.9
ICD-10 Finland
Zoster without complication
2.3
7.6
69
313
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.8
7.6
124
710
R30.0
ICD-10 Finland
Dysuria
2.7
7.6
49
185
F51.0
ICD-10 Finland
Nonorganic insomnia
1.7
7.5
152
932
N06AB06
ATC
sertraline; oral
1.8
7.5
130
758
U01
ICPC
Dysuria/painful urination
2.0
7.5
99
527
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
7.5
93
484
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.4
7.5
415
3228
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.1
7.4
79
385
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.1
7.4
39
130
A02BX02
ATC
sucralfate; oral
2.6
7.4
52
207
WZA90
NOMESCO Finland
Other doctors statement
1.5
7.4
255
1795
D09
ICPC
Nausea
2.4
7.4
63
276
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
7.4
127
742
ZXA05
NOMESCO Finland
Left side
1.5
7.3
268
1915
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.6
7.3
209
1409
N05BA06
ATC
lorazepam; systemic, sublingual
2.4
7.3
60
257
U05
ICPC
Urination problems other
2.5
7.3
54
221
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
7.3
225
1546
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.8
7.3
43
155
R09
ICPC
Sinus symptom/complaint
2.0
7.2
91
476
M77.4
ICD-10 Finland
Metatarsalgia
2.3
7.2
66
301
R03AK08
ATC
formoterol and beclometasone; inhalant
2.6
7.2
51
204
N03AX09
ATC
lamotrigine; oral
2.4
7.2
60
262
R29
ICPC
Respiratory symptom/complaint other
2.2
7.2
73
350
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
7.2
122
709
C10AA03
ATC
pravastatin; oral
2.1
7.2
75
364
R4120
NOMESCO Finland
Occupational therapy
2.2
7.2
72
341
L09
ICPC
Arm symptom/complaint
2.4
7.1
56
235
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.0
7.1
94
500
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.5
7.1
51
206
K29.1
ICD-10 Finland
Other acute gastritis
5.1
7.1
21
42
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.3
7.1
33
101
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.2
7.1
65
298
D20
ICPC
Mouth/tongue/lip symptom/complaint
2.5
7.1
54
226
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.8
7.1
42
152
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
7.1
112
636
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.2
7.0
34
107
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
2.0
7.0
93
494
F45.0
ICD-10 Finland
Somatization disorder
10.1
7.0
13
13
D19
ICPC
Teeth/gum symptom/complaint
1.5
7.0
272
1967
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.2
7.0
66
303
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.9
7.0
40
140
A03CA02
ATC
clidinium and psycholeptics; oral
2.1
7.0
76
376
SPAT1104
SPAT
Monitoring of emergency patient
2.1
6.9
76
377
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.0
6.9
88
460
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
5.5
6.9
19
35
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.6
6.9
48
189
S04
ICPC
Lump/swelling localized
1.9
6.9
105
586
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
3.0
6.9
37
126
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
3.0
6.9
37
126
SGA01
NOMESCO Finland
Tooth opening as first aid
1.6
6.9
169
1097
R04.0
ICD-10 Finland
Epistaxis
2.1
6.9
75
371
C10AA01
ATC
simvastatin; oral
1.4
6.8
403
3162
M77.1
ICD-10 Finland
Lateral epicondylitis
2.0
6.8
79
399
M48.0
ICD-10 Finland
Spinal stenosis
1.8
6.8
121
715
L19
ICPC
Muscle symptom/complaint NOS
3.2
6.8
34
110
ZXA10
NOMESCO Finland
Bilateral
1.6
6.8
202
1374
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.4
6.8
52
218
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.4
6.8
54
230
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
6.8
148
927
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.9
6.7
100
555
SPAT1252
SPAT
Overall medication plan or its review
2.1
6.7
72
354
M47.81
ICD-10 Finland
Other spondylosis, occipito-atlanto-axial region
7.2
6.7
15
21
R83
ICPC
Respiratory infection other
1.5
6.7
272
1981
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
3.8
6.7
26
69
E66.00
ICD-10 Finland
Metabolic syndrome
2.3
6.7
57
253
Z50.1
ICD-10 Finland
Other physical therapy
2.2
6.6
62
287
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.3
6.6
57
254
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.9
6.6
101
565
SDA02
NOMESCO Finland
Parodonthologic therapy
1.4
6.6
348
2669
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.9
6.6
101
566
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
6.6
285
2105
SPAT1251
SPAT
Organisation of medication
2.6
6.6
46
182
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
6.6
99
553
N05CF02
ATC
zolpidem; oral
1.6
6.6
188
1266
F34.1
ICD-10 Finland
Dysthymia
2.7
6.6
42
157
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
2.9
6.5
36
125
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.0
6.5
75
379
S01
ICPC
Pain/tenderness of skin
2.5
6.5
49
202
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
6.5
102
576
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.6
6.5
200
1370
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
6.5
100
561
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.9
6.5
96
532
C03CA01
ATC
furosemide; systemic
1.5
6.4
270
1978
R06.2
ICD-10 Finland
Wheezing
2.3
6.4
55
244
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.8
6.4
39
144
I95.1
ICD-10 Finland
Orthostatic hypotension
2.8
6.4
38
138
A05
ICPC
Feeling ill
2.0
6.4
76
389
I25.2
ICD-10 Finland
Old myocardial infarction
2.3
6.4
57
257
M67.4
ICD-10 Finland
Ganglion
2.1
6.4
72
362
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
6.4
207
1434
N05AH03
ATC
olanzapine; systemic
2.1
6.4
67
326
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.8
6.4
103
590
K92.1
ICD-10 Finland
Melaena
2.3
6.4
54
237
D07AA02
ATC
hydrocortisone; topical
1.6
6.4
152
979
IGY99
NOMESCO Finland
Other psychiatric treatment contact
3.4
6.3
28
83
R01AD05
ATC
budesonide; nasal
1.9
6.3
86
464
S29.9
ICD-10 Finland
Unspecified injury of thorax
6.6
6.3
15
23
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.8
6.3
106
613
K14.61
ICD-10 Finland
Glossodynia
8.2
6.3
13
16
ZX120
NOMESCO Finland
Intravenous
1.8
6.3
104
597
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
6.3
532
4423
J05AB11
ATC
valaciclovir; oral
1.7
6.3
142
897
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.8
6.3
111
654
WX320
NOMESCO Finland
Spinalanesthesy
1.5
6.3
225
1594
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
2.2
6.3
62
295
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.0
6.3
81
428
UJF92
NOMESCO Finland
Capsular endoscopy
3.2
6.2
30
95
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.2
6.2
59
275
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.9
6.2
34
118
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.5
6.2
47
195
SPAT1100
SPAT
Long-term monitoring of blood pressure
2.1
6.2
70
351
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
6.2
72
365
81
HP
Angiography of the heart and coronary arteries
2.2
6.2
58
268
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.4
6.2
278
2065
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
5.8
6.1
16
28
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.7
6.1
113
674
G04BD04
ATC
oxybutynin; oral, transdermal
2.1
6.1
65
317
WVA20
NOMESCO Finland
Medicine administration
3.2
6.1
29
91
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
2.1
6.1
61
292
R25.1
ICD-10 Finland
Tremor, unspecified
2.9
6.1
35
123
S69.9
ICD-10 Finland
Unspecified injury of wrist and hand
3.7
6.1
24
65
C08DA01
ATC
verapamil; systemic
2.4
6.1
47
199
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.2
6.1
58
272
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
2.6
6.1
41
162
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.8
6.1
100
576
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.0
6.0
71
361
R4110
SPAT
NA
2.7
6.0
39
147
S60.0
ICD-10 Finland
Contusion of finger(s) without damage to nail
2.7
6.0
39
148
P76
ICPC
Depressive disorder
1.9
6.0
79
419
S50.0
ICD-10 Finland
Contusion of elbow
2.8
6.0
36
132
RF210
NOMESCO Finland
NA
2.8
6.0
36
132
K76
ICPC
Ischaemic heart dis without angina
3.6
6.0
25
71

Mortality – FinRegistry

Association

Association between endpoint M13_TIETZE and mortality.

Females

Parameter HR [95% CI] p-value
M13_TIETZE 1.184 [1.03, 1.36] 0.015
Birth year 0.996 [0.99, 1.01] 0.358

During the follow-up period (1.1.1998 — 31.12.2019), 704 out of 5082 females with M13_TIETZE died.

Males

Parameter HR [95% CI] p-value
M13_TIETZE 1.178 [0.96, 1.44] 0.113
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 236 out of 2124 males with M13_TIETZE died.

Mortality risk

Mortality risk for people of age

years, who have M13_TIETZE.

N-year risk Females Males
1 0.131% 0.197%
5 0.686% 1.305%
10 1.56% 3.212%
15 3.269% 6.432%
20 5.964% 11.041%

Relationships between endpoints

Index endpoint: M13_TIETZE – Chondrocostal junction syndrome [Tietze]

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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