Oher contracture of tendon (sheath)

M13_TENDONCONTRACT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M67.1
  • Cause of death: ICD-10 M67.1

2 out of 7 registries used, show all original rules.

127

4. Check minimum number of events

None

127

5. Include endpoints

None

127

6. Filter based on genotype QC (FinnGen only)

127

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M67
Name in latin
Alia contractura tendinis et vaginae tendinis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 895 394 498
Only index persons 856 381 475
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.02 0.01 0.02
Median age at first event (years)
Whole population 54.47 52.79 55.66
Only index persons 53.77 52.82 54.53

-FinnGen-

Key figures

All Female Male
Number of individuals 127 66 61
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 55.66 53.29 58.23

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
115
Matched controls
1151
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M67.1
ICD-10 Finland
Other contracture of tendon (sheath)
+∞
166.0
115
*
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
219.0
32.5
32
*
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
332.1
26.9
26
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
9.2
15.1
33
48
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
+∞
14.9
14
*
M65.3
ICD-10 Finland
Trigger finger
35.1
14.4
18
6
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
+∞
11.7
11
*
M67.4
ICD-10 Finland
Ganglion
19.7
11.6
17
10
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.8
9.8
36
100
ACC51
NOMESCO Finland
Release of median nerve
9.1
8.8
18
23
M19.0
ICD-10 Finland
Primary arthrosis of other joints
7.4
8.1
19
30
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
14.7
7.6
12
9
N02AX02
ATC
tramadol; systemic, rectal
3.0
7.3
56
276
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
42.6
6.8
8
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
4.1
6.8
27
80
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
73.8
6.5
7
*
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
+∞
6.3
6
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
6.2
6.3
16
29
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
13.5
6.2
10
8
ZXA05
NOMESCO Finland
Left side
3.3
6.2
36
141
N03AX12
ATC
gabapentin; oral
4.2
6.2
23
64

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(42870588) Differential panel, method unspecified - Blood
54
305
2.34
5.05
5.8
5.0
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
74
478
2.31
5.04
6.2
5.3
e9/l
1.9
1.8
0.83
67
433
(3006315) Basophils [#/volume] in Blood
73
474
2.27
4.85
6.3
5.3
e9/l
0.0
0.0
0.24
61
420
(3001604) Monocytes [#/volume] in Blood
73
474
2.27
4.85
6.3
5.2
e9/l
0.6
0.6
0.04
61
419
(3013115) Eosinophils [#/volume] in Blood
74
484
2.27
4.82
6.4
5.5
e9/l
0.2
0.2
0.67
64
437
(3018010) Neutrophils/100 leukocytes in Blood
69
440
2.24
4.76
5.5
5.4
%
55.8
58.3
0.83
64
420
(3002030) Lymphocytes/100 leukocytes in Blood
70
452
2.22
4.65
6.1
5.5
%
28.6
27.4
0.35
64
429
(3022096) Basophils/100 leukocytes in Blood
67
426
2.21
4.62
6.3
5.3
%
0.7
0.7
0.33
62
406
(3006504) Eosinophils/100 leukocytes in Blood
67
438
2.12
4.18
6.5
5.4
%
3.0
2.8
0.44
62
414
(3019069) Monocytes/100 leukocytes in Blood
67
442
2.09
4.04
6.4
5.6
%
9.2
8.8
0.50
62
422
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
28
129
2.50
4.01
1.3
1.2
u/ml
1.3
14.4
—
10
53
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
58
375
2.01
3.58
2.1
1.8
pmol/l
94.8
94.5
0.01
30
204
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
29
148
2.24
3.29
1.6
1.8
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
119
1049
3.13
3.21
21.6
14.6
mmol/l
139.8
139.8
0.03
119
1019
(3044290) Cell count panel - Cerebral spinal fluid
6
8
7.80
3.09
1.0
1.8
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
47
299
1.91
2.93
4.1
2.1
u/l
55.7
56.0
0.03
40
272
(3007853) Bacteria identified in Skin by Aerobe culture
19
85
2.45
2.87
1.4
1.4
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
90
708
1.93
2.84
4.9
3.7
mm/h
12.6
11.7
0.26
82
650
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
26
137
2.13
2.71
1.2
1.2
iu/ml
24.3
52.8
—
7
49
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
77
582
1.82
2.70
3.1
2.9
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
121
1095
3.22
2.67
13.9
9.7
u/l
25.4
26.5
0.33
121
1058
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
32
186
1.96
2.56
1.6
1.6
mg/l
0.8
1.2
1.30
23
150
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
117
1032
2.70
2.48
5.3
4.9
mmol/l
2.6
2.8
1.00
110
959
(3023368) Bacteria identified in Blood by Culture
39
246
1.84
2.44
5.8
4.2
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
73
558
1.72
2.33
8.1
9.0
e9/l
3.9
4.2
0.78
66
496
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
114
1002
2.35
2.29
4.5
4.3
mmol/l
1.5
1.5
0.14
107
929
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
107
919
2.04
2.27
5.2
4.0
mu/l
1.9
2.0
0.22
97
825
(3032080) INR in Blood by Coagulation assay
54
382
1.72
2.27
9.8
7.4
inr
1.3
1.2
—
10
113
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
107
923
2.01
2.19
6.9
5.7
mmol/mol
41.8
40.0
0.92
100
861
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
20
104
2.10
2.15
1.5
1.8
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
111
973
2.12
2.12
4.1
3.9
mmol/l
1.1
1.3
2.15
105
901
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
89
730
1.73
2.10
4.2
3.4
pmol/l
15.0
14.7
0.49
77
652
(40761511) CBC panel - Blood by Automated count
118
1071
2.44
2.07
19.6
12.3
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
20
106
2.05
2.05
1.6
1.7
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
83
671
1.68
2.04
5.4
3.9
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
59
439
1.64
1.99
4.8
3.7
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
113
1006
2.12
1.92
19.8
12.7
mg/l
26.7
25.4
0.16
101
771
(3004588) Protein electrophoresis panel - Serum or Plasma
13
59
2.34
1.91
1.7
2.2
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
27
164
1.82
1.88
1.7
1.6
nmol/l
1271.4
1171.2
0.19
19
130
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
16
81
2.12
1.84
2.8
3.5
—
—
—
0
0
(4010399)
15
75
2.13
1.78
1.9
1.4
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
43
308
1.60
1.64
3.0
3.5
mmol/l
2.4
2.4
0.19
33
275
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
18
100
1.93
1.63
1.3
1.5
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
41
292
1.60
1.59
4.4
3.3
mg/l
26.6
79.3
1.88
24
190
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
10
44
2.38
1.57
8.3
7.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
105
930
1.74
1.57
18.7
13.4
%
38.9
40.1
0.57
74
683
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
30
199
1.66
1.54
1.2
1.2
u/ml
1.3
0.6
—
5
54
(3044889) 12 lead EKG panel
85
719
1.55
1.50
4.2
3.8
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
5
16
3.21
1.45
3.2
2.7
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
10
46
2.27
1.44
8.9
5.2
mmol/l
23.4
24.7
—
10
46
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
10
47
2.22
1.37
1.2
1.9
mg/l
2.1
4.6
—
10
34
(1616796) Gas panel - Central venous blood
5
17
3.02
1.37
8.6
3.4
—
—
—
0
0
(3019225) pH of Specimen
16
91
1.87
1.36
4.5
5.3
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
54
423
1.48
1.33
8.0
5.8
mmol/l
1.2
1.2
0.02
47
389
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
8
35
2.37
1.29
2.0
2.0
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
58
464
1.46
1.27
9.4
6.7
mmol/l
1.2
1.2
0.13
52
398
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
19
117
1.73
1.27
13.8
8.0
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
41
307
1.50
1.25
4.2
3.1
mmol/l
7.5
8.1
0.54
34
266
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
8
37
2.24
1.24
1.1
1.0
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
30
210
1.56
1.24
6.5
5.0
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
70
583
1.45
1.23
6.1
4.1
mmol/l
7.0
6.7
0.58
65
546
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
19
2.70
1.22
1.2
1.2
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
5
19
2.70
1.22
1.2
1.2
g/l
0.0
0.0
—
5
19
(3020682) Albumin/Creatinine [Ratio] in Urine
41
312
1.46
1.14
5.2
4.0
mg/mmol
5.0
13.1
1.23
24
200
(40768443) Skin Pathology biopsy report
8
41
2.01
1.11
1.8
1.3
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
5
21
2.44
1.10
1.6
3.6
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
18
114
1.67
1.10
1.2
1.3
titre
373.3
304.3
—
6
28
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
13
75
1.82
1.07
2.0
2.6
ml/min/173m2
75.7
60.7
—
6
26
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
7
33
2.18
1.07
1.1
1.2
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
7
33
2.18
1.07
2.0
1.7
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
9
46
2.03
1.06
2.7
2.3
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
22
2.32
1.04
1.2
1.0
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
5
22
2.32
1.04
1.0
1.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
9
48
1.94
1.03
1.2
1.7
—
—
—
0
0
(3019060) Gas panel - Arterial blood
11
63
1.82
0.93
4.7
3.5
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
6
28
2.20
0.93
5.2
2.7
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
10
56
1.85
0.90
1.6
1.4
—
—
—
0
0
(3012544) pH of Venous blood
15
96
1.64
0.89
3.6
3.8
—
—
—
0
0
(3034860) Kappa light chains.free [Mass/volume] in Serum
6
30
2.05
0.88
1.5
2.8
mg/l
38.3
105.4
—
6
23
(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma
6
30
2.05
0.88
1.5
2.9
mg/l
30.2
32.3
—
6
23
(3003396) Base excess in Arterial blood by calculation
16
105
1.60
0.86
8.2
5.5
mmol/l
0.1
0.8
0.42
11
85
(3018418) pH of Serum or Plasma
37
292
1.38
0.83
6.3
4.2
ph
7.4
7.4
—
5
60
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
24
175
1.46
0.82
4.5
3.6
ng/l
46.0
205.9
1.32
16
143
(3004716) Salmonella sp identified in Stool by Organism specific culture
8
47
1.75
0.82
1.5
1.5
—
—
—
0
0
(3000492) Spirometry study
13
82
1.65
0.81
1.4
1.6
—
—
—
0
0
(4034850)
6
33
1.86
0.80
21.2
8.1
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
24
177
1.44
0.78
3.3
2.4
e6/l
2.3
1.1
0.72
15
105
(40761535) Cells panel - Urine sediment
12
75
1.66
0.78
3.9
3.8
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
57
486
1.31
0.76
5.1
3.3
estimate
0.0
0.0
—
8
82
(3021589) Normoblasts [#/volume] in Blood
53
448
1.31
0.75
12.5
8.9
e9/l
0.0
0.0
0.50
38
367
(3003327) Ova and parasites identified in Stool by Light microscopy
5
24
2.13
0.75
1.8
1.3
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
11
68
1.68
0.74
1.3
1.1
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
18
128
1.47
0.70
3.9
2.5
%
19.4
22.6
0.51
13
113
(3022313) Gas panel - Capillary blood
7
43
1.66
0.68
5.6
4.6
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
43
1.66
0.68
1.1
1.2
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
56
483
1.29
0.67
5.1
3.3
estimate
0.0
0.0
—
8
87
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
13
87
1.55
0.66
1.3
1.3
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
45
379
1.29
0.64
3.9
3.6
ng/l
21.8
32.9
0.87
35
257
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
8
50
1.64
0.62
1.3
2.0
g/l
1.2
1.3
—
8
44
(3025941) Bacteria identified in Stool by Culture
8
51
1.61
0.62
1.1
1.4
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
21
0.00
0.60
0.0
3.5
—
59.0
—
0
21
(3017044) Thyrotropin receptor Ab [Units/volume] in Serum
0
22
0.00
0.60
0.0
1.5
—
3.0
—
0
5
(3013512) EKG study
34
280
1.29
0.57
5.2
3.8
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
55
482
1.25
0.56
6.6
4.6
estimate
0.0
0.0
—
9
87
(3042936) Bacteria identified in Isolate by Culture
18
135
1.39
0.55
2.2
2.0
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
26
209
1.31
0.52
4.8
3.1
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
9
65
1.41
0.52
4.3
2.7
g/l
128.2
127.9
—
9
65
(3017143) Hepatitis C virus Ab [Presence] in Serum
15
111
1.40
0.49
1.7
1.5
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
33
279
1.25
0.45
4.8
2.8
e6/l
0.6
0.5
0.07
26
205
(40768804) Tissue Pathology biopsy report
45
395
1.22
0.44
1.9
2.1
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
17
132
1.33
0.43
1.7
1.6
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
44
386
1.21
0.43
5.2
3.5
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
25
206
1.27
0.42
1.6
1.7
pmol/l
611111540.6
414.2
0.48
18
184
(40768795) Lymph node Pathology biopsy report
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
0
16
0.00
0.41
0.0
1.9
—
67.0
—
0
16
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
42
374
1.18
0.34
4.8
2.9
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
31
269
1.20
0.33
5.8
2.6
—
—
—
0
0
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
6
46
1.32
0.33
1.0
2.6
u/l
51.2
37.2
—
6
41
(3000330) Specific gravity of Urine by Test strip
6
47
1.29
0.33
9.7
4.3
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
35
309
1.18
0.31
5.5
4.4
%
22.1
20.7
0.23
18
154
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
7
53
1.34
0.31
1.6
3.6
%
62.7
50.2
—
7
53
(3001019) Free T4 and TSH panel - Serum or Plasma
7
56
1.26
0.30
1.6
1.6
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
7
57
1.24
0.29
12.1
5.8
%
92.3
94.6
—
7
57
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
26
225
1.20
0.29
3.4
2.9
ug/l
0.6
0.9
1.18
16
149
(40758558) Short blood count panel - Blood
29
254
1.18
0.28
3.7
7.0
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
15
122
1.26
0.28
1.2
1.2
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
26
226
1.19
0.28
2.5
2.3
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
101
975
1.18
0.26
15.7
12.3
ml/min/173m2
79.8
80.1
0.05
84
789
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
19
162
1.20
0.24
3.8
2.6
e6/l
2.9
2.0
0.25
11
92
(3007164) IgA [Mass/volume] in Serum or Plasma
23
200
1.18
0.24
1.3
1.4
g/l
2.5
2.3
0.42
11
129
(3029937) Albumin [Presence] in Urine by Test strip
29
258
1.16
0.24
5.3
3.6
estimate
0.0
0.0
—
7
82
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
5
37
1.37
0.24
1.0
1.0
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
30
268
1.16
0.23
4.4
2.7
—
—
—
0
0
(3020891) Body temperature
5
38
1.33
0.23
3.8
4.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
14
116
1.23
0.23
1.5
1.4
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
5
39
1.29
0.23
1.2
1.4
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
0
10
0.00
0.21
0.0
2.6
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
(21494434) Karyotype in Bone marrow
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
(3039162) Centromere protein B Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(4281824)
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
12
0.00
0.21
0.0
3.0
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
34
309
1.14
0.21
4.8
2.9
e6/l
91.8
44.0
0.34
27
236
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
39
359
1.12
0.20
4.9
3.2
e6/l
307.5
88.2
0.44
29
259
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
5
66
0.75
0.17
2.0
1.5
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
8
68
1.19
0.17
1.4
1.5
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
8
70
1.15
0.16
6.4
4.4
ng/l
95.5
88.3
—
8
62
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
8
71
1.14
0.16
2.8
1.5
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
6
77
0.77
0.16
1.0
2.2
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
33
305
1.11
0.15
2.6
2.2
—
—
—
0
0
(3000991) Gas panel - Venous blood
10
84
1.21
0.14
8.7
6.3
—
—
—
0
0
(4035726)
8
97
0.81
0.14
1.5
1.4
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
8
99
0.80
0.14
2.4
1.7
—
—
—
0
0
(3022145) Colonoscopy Study observation
12
104
1.17
0.13
1.6
1.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
16
144
1.13
0.11
1.5
1.6
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
17
154
1.12
0.10
1.7
1.8
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
5
48
1.04
0.09
2.0
3.2
pmol/l
3.3
4.3
—
5
42
(3019832) Treponema pallidum Ab [Presence] in Serum
8
73
1.10
0.08
1.3
1.8
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
8
78
1.03
0.07
1.3
1.6
nmol/l
314.6
366.4
—
8
72
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
7
83
0.83
0.07
1.0
2.2
—
—
—
0
0
(3002256) Pathology report gross observation
12
130
0.92
0.05
1.3
1.3
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
42
408
1.04
0.04
3.3
2.4
ug/l
133.3
110.7
0.30
36
379
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
15
160
0.93
0.04
1.3
1.4
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
29
282
1.04
0.02
4.9
3.1
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
26
257
1.01
0.00
1.3
1.4
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
39
387
1.01
0.00
2.8
2.7
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
11
108
1.02
0.00
1.3
1.4
—
—
—
0
0
(3000034) Microalbumin [Mass/volume] in Urine
0
8
0.00
0.00
0.0
4.8
—
5.6
—
0
8
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022621) pH of Urine by Test strip
5
50
1.00
0.00
2.2
2.3
—
—
—
0
0
(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
6
0.00
0.00
0.0
1.2
—
10.0
—
0
6
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3028433) Virus identified in Specimen by Culture
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
26.3
—
0
6
(3035637) Corticotropin [Mass/volume] in Plasma
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044007) Cell count panel - Peritoneal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3024263) Appearance of Synovial fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
8.5
—
0.6
—
0
8
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3037692) Legionella sp identified in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
(3000012) Reticulocyte production index
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(42529582) MDA5 Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.8
—
85.2
—
0
5
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3013727) Leukocytes other/100 leukocytes in Blood
0
5
0.00
0.00
0.0
2.6
—
62.2
—
0
5
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
26
260
1.00
0.00
1.4
1.6
mmol/l
1.2
1.4
0.55
20
215
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3013637) Mi-2 Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014271) Vancomycin [Susceptibility]
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
7
79
0.88
0.00
7.3
3.2
—
—
—
0
0
(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
16.3
—
0
5
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3012565) Volume of 24 hour Urine
0
5
0.00
0.00
0.0
4.0
—
2530.0
—
0
5
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.8
—
841.5
—
0
6
(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
8
0.00
0.00
0.0
1.0
—
11.1
—
0
8
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008536) Aspergillus sp Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_TENDONCONTRACT and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
M13_TENDONCONTRACT 0.751 [0.57, 0.99] 0.041
Birth year 0.991 [0.98, 1.0] 0.042

During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 451 males with M13_TENDONCONTRACT died.

Mortality risk

Mortality risk for people of age

years, who have M13_TENDONCONTRACT.

N-year risk Females Males
1 No data 0.162%
5 No data 0.972%
10 No data 2.63%
15 No data 4.932%
20 No data 8.201%

Relationships between endpoints

Index endpoint: M13_TENDONCONTRACT – Oher contracture of tendon (sheath)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data