Synovial hypertrophy, not elsewhere classified

M13_SYNOHYPERTROPH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M67.2
  • Cause of death: ICD-10 M67.2

2 out of 7 registries used, show all original rules.

376

4. Check minimum number of events

None

376

5. Include endpoints

None

376

6. Filter based on genotype QC (FinnGen only)

376

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M67
Name in latin
Hypertrophia membranae synovialis non alibi classificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3056 1552 1498
Only index persons 3008 1538 1470
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.04
Only index persons 0.06 0.06 0.06
Median age at first event (years)
Whole population 36.05 35.31 36.81
Only index persons 36.00 35.29 36.74

-FinnGen-

Key figures

All Female Male
Number of individuals 376 221 155
Unadjusted period prevalence (%) 0.07 0.08 0.07
Median age at first event (years) 38.14 36.49 40.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
343
Matched controls
3430
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M67.2
ICD-10 Finland
Synovial hypertrophy, not elsewhere classified
+∞
323.0
343
*
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
127.4
142.8
147
20
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
17.6
55.8
91
69
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
9.1
42.7
98
145
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
61.2
37.3
43
8
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
13.3
33.9
61
55
M22.4
ICD-10 Finland
Chondromalacia patellae
15.9
31.5
52
38
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
6.8
30.9
85
159
M25.5
ICD-10 Finland
Pain in joint
4.2
29.5
142
493
M79.6
ICD-10 Finland
Pain in limb
3.9
25.9
136
497
M17.1
ICD-10 Finland
Other primary gonarthrosis
5.1
25.9
92
231
M01AH05
ATC
etoricoxib; oral
3.1
21.1
234
1410
M01AX05
ATC
glucosamine; oral
4.4
19.1
75
204
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
20.2
19.0
28
15
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
18.5
183
992
N02AX02
ATC
tramadol; systemic, rectal
2.9
17.9
149
720
M23.8
ICD-10 Finland
Other internal derangements of knee
9.9
17.9
36
40
M01AB05
ATC
diclofenac; systemic, rectal
2.8
17.4
250
1671
N03AX12
ATC
gabapentin; oral
4.2
15.9
65
182
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
5.1
15.9
52
116
S83.2
ICD-10 Finland
Tear of meniscus, current
5.3
14.8
46
97
N02AJ06
ATC
codeine and paracetamol; systemic
2.6
14.5
146
766
M67.4
ICD-10 Finland
Ganglion
10.1
14.2
28
30
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.4
14.0
73
250
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
11.6
13.7
25
23
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
+∞
13.6
13
*
M67.8
ICD-10 Finland
Other specified disorders of synovium and tendon
145.5
13.5
14
*
S18
ICPC
Laceration/cut
2.5
13.2
141
753
M01AX17
ATC
nimesulide; oral
3.0
12.8
85
344
M01AE02
ATC
naproxen; oral, rectal
2.3
12.7
210
1388
M19.0
ICD-10 Finland
Primary arthrosis of other joints
5.4
12.6
38
77
M03BX02
ATC
tizanidine; oral
2.3
12.5
229
1585
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
5.7
12.2
35
67
L15
ICPC
Knee symptom/complaint
3.0
11.7
74
289
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
124.0
11.5
12
*
M01AC06
ATC
meloxicam; systemic, rectal
2.4
11.2
124
662
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
44.8
11.0
13
*
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
8.4
10.8
23
29
M02AA07
ATC
piroxicam; topical
2.4
10.8
118
624
N03AX16
ATC
pregabalin; oral
2.8
10.7
79
336
M54.5
ICD-10 Finland
Low back pain
2.3
10.1
116
625
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.3
10.0
52
176
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.5
9.9
35
85
M01AH01
ATC
celecoxib; oral (coxibs)
2.9
9.8
64
254
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.9
9.7
40
112
H02AB06
ATC
prednisolone; systemic
2.1
9.7
153
948
L03
ICPC
Low back symptom/complaint
2.5
9.6
83
386
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
3.8
9.6
40
114
M01AH02
ATC
rofecoxib; oral
3.5
9.4
44
138
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
9.2
127
738
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
9.1
120
684
M01AE01
ATC
ibuprofen; systemic, rectal
3.2
9.1
320
2781
NGE10
NOMESCO Finland
Incision or suture of capsule of knee joint
37.8
9.1
11
*
N02BE01
ATC
paracetamol; systemic, rectal
2.3
9.0
285
2325
1220
FHL
Arthroscopy
6.2
8.9
23
39
ZXA00
NOMESCO Finland
Right side
2.4
8.8
81
387
M77.1
ICD-10 Finland
Lateral epicondylitis
4.0
8.5
33
88
ZXE00
NOMESCO Finland
One hour or less
2.0
8.4
142
890
NGF10
NOMESCO Finland
Total synovectomy of knee, open
+∞
8.4
8
*
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
+∞
8.4
8
*
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
7.1
8.2
19
28
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
8.1
115
669
WX320
NOMESCO Finland
Spinalanesthesy
2.4
8.1
77
375
M02AA10
ATC
ketoprofen; topical
2.8
7.9
52
204
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.8
7.9
50
194
J01AA02
ATC
doxycycline; systemic
2.0
7.7
256
2038
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
7.7
88
466
R03AC02
ATC
salbutamol; inhalant
1.9
7.6
179
1254
WX110
NOMESCO Finland
Local anesthesy
1.9
7.5
244
1917
A02BC05
ATC
esomeprazole; systemic
2.0
7.5
127
790
S43.4
ICD-10 Finland
Sprain and strain of shoulder joint
7.1
7.4
17
25
M03BC01
ATC
orphenadrine (citrate); systemic
2.1
7.2
91
502
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
6.8
7.2
17
26
S60.0
ICD-10 Finland
Contusion of finger(s) without damage to nail
5.9
7.2
19
34
NGE15
NOMESCO Finland
Incision fo capsule of knee joint, arthroscopic
20.5
7.2
10
5
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
7.1
88
479
ZXD20
NOMESCO Finland
Day surgery
2.7
7.1
48
193
M48.0
ICD-10 Finland
Spinal stenosis
3.5
7.1
32
98
M09AX01
ATC
hyaluronic acid; parenteral
5.7
7.0
19
35
M79.5
ICD-10 Finland
Residual foreign body in soft tissue
14.1
6.9
11
8
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
6.3
6.9
17
28
J45.9
ICD-10 Finland
Asthma, unspecified
2.5
6.8
55
244
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
6.8
126
801
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
40.9
6.8
8
*
M94.2
ICD-10 Finland
Chondromalacia
17.1
6.8
10
6
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.8
6.7
43
168
NBG10
NOMESCO Finland
Acromioplastia
23.0
6.7
9
*
ZXA05
NOMESCO Finland
Left side
2.2
6.7
72
367
R51.80
ICD-10 Finland
Headache
2.5
6.7
54
239
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
6.6
80
432
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.4
6.6
22
52
L17
ICPC
Foot/toe symptom/complaint
2.2
6.6
73
378
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.8
6.2
25
70
J01DB01
ATC
cefalexin; oral
2.0
6.2
277
2337
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
6.2
59
287
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.2
6.1
30
99
L08
ICPC
Shoulder symptom/complaint
2.4
6.1
53
245
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
10.3
6.1
11
11
W22
ICD-10 Finland
Striking against or struck by other object(s)
3.3
6.1
29
94

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
90
439
2.38
10.70
1.4
1.2
iu/ml
16.0
34.8
2.02
34
137
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
83
414
2.29
9.27
1.4
1.2
u/ml
15.3
11.2
0.12
27
175
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
20
45
4.64
8.47
1.7
1.4
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
261
2034
1.93
7.78
4.7
3.4
mm/h
9.8
9.9
0.03
251
1897
(3026493) Urate [Moles/volume] in Serum or Plasma
102
632
1.84
6.07
2.4
2.7
umol/l
325.0
8159.4
3.09
92
562
(3037522) Nuclear Ab [Titer] in Serum
67
369
1.99
5.65
1.7
1.3
titre
406.7
455.5
0.12
12
67
(3013826) Glucose [Moles/volume] in Serum or Plasma
200
1538
1.64
5.27
4.1
4.7
mmol/l
6.6
6.6
0.02
186
1401
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
314
2737
1.89
5.05
4.9
4.2
mu/l
1.8
1.8
0.07
292
2535
(3008898) HLA-B27 [Presence]
30
124
2.54
5.02
1.0
1.1
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
269
2247
1.69
4.98
4.2
3.7
pmol/l
14.7
14.5
0.74
252
2060
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
338
3029
2.15
4.90
13.5
10.6
mg/l
19.6
22.6
0.92
266
2290
(3044941) Cell count panel - Synovial fluid
12
28
4.39
4.86
1.3
1.5
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
47
244
2.06
4.65
10.6
16.0
inr
1.1
1.2
0.41
14
38
(3019550) Sodium [Moles/volume] in Serum or Plasma
336
3035
2.01
4.28
12.9
11.7
mmol/l
139.7
139.7
0.06
327
2954
(3021960) Folate [Moles/volume] in Serum or Plasma
78
500
1.71
4.00
1.4
1.4
nmol/l
19.4
20.5
0.31
69
433
(3027315) Oxygen [Partial pressure] in Blood
14
43
3.34
3.94
2.2
2.5
kpa
9.4
9.1
0.17
14
43
(3013290) Carbon dioxide [Partial pressure] in Blood
14
43
3.34
3.94
2.2
2.5
kpa
5.1
4.9
0.47
14
43
(3013512) EKG study
99
679
1.62
3.92
3.5
3.2
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
175
1368
1.52
3.89
5.5
5.8
%
29.7
29.2
0.27
164
1293
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
35
174
2.12
3.89
2.2
2.4
au/ml
7.5
12.3
—
5
9
(3019198) Lymphocytes [#/volume] in Blood
182
1435
1.52
3.88
5.1
5.7
e9/l
2.2
1.9
0.52
164
1279
(42870588) Differential panel, method unspecified - Blood
124
899
1.57
3.88
4.4
5.6
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
138
1025
1.55
3.88
4.8
4.8
g/l
37.3
36.4
1.16
133
968
(3023103) Potassium [Moles/volume] in Serum or Plasma
335
3048
1.91
3.80
13.1
11.9
mmol/l
4.0
3.9
0.42
326
2959
(3022145) Colonoscopy Study observation
51
293
1.86
3.78
1.2
1.3
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
172
1349
1.51
3.71
5.8
5.7
%
56.6
56.4
0.10
161
1276
(3045414) Leukocytes [Presence] in Urine
22
92
2.48
3.63
2.6
1.5
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
21
86
2.53
3.62
1.8
1.8
—
—
—
0
0
(3044889) 12 lead EKG panel
234
1965
1.51
3.57
3.3
3.1
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
11
31
3.63
3.51
1.8
1.7
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
74
487
1.65
3.42
2.9
2.3
e6/l
3.8
7.4
1.33
66
426
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
164
1294
1.47
3.34
4.1
4.0
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
96
677
1.56
3.33
1.3
1.2
u/ml
2.4
2.0
0.10
23
187
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
42
237
1.87
3.30
3.3
2.8
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
59
370
1.71
3.27
2.1
2.5
ug/g
96.8
126.5
0.40
51
291
(3006504) Eosinophils/100 leukocytes in Blood
166
1319
1.46
3.23
5.5
5.8
%
2.8
2.8
0.04
154
1236
(3001604) Monocytes [#/volume] in Blood
173
1391
1.45
3.14
5.2
5.6
e9/l
0.5
0.6
0.04
150
1217
(3022096) Basophils/100 leukocytes in Blood
161
1277
1.46
3.14
5.5
5.9
%
0.6
0.7
1.49
151
1196
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
170
1364
1.45
3.11
5.0
6.5
umol/l
10.5
10.5
0.02
164
1303
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
111
821
1.50
3.07
2.0
2.3
u/l
53.1
57.6
0.83
104
768
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
36
198
1.90
3.06
3.2
2.5
ml/min/173m2
71.6
71.0
—
5
80
(3006315) Basophils [#/volume] in Blood
173
1396
1.44
3.06
5.2
5.6
e9/l
0.0
0.0
0.61
153
1223
(3000570) Elastase.pancreatic [Mass/mass] in Stool
17
69
2.53
3.00
1.4
1.3
ug/g
391.5
360.1
0.26
12
38
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
84
590
1.55
2.95
1.6
1.6
mg/l
0.7
1.0
1.34
61
434
(3019069) Monocytes/100 leukocytes in Blood
165
1327
1.43
2.94
5.8
6.1
%
8.0
8.5
1.18
155
1254
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
13
47
2.83
2.84
2.2
1.2
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
121
924
1.46
2.82
1.9
1.7
pmol/l
100.8
96.1
0.56
71
485
(3013115) Eosinophils [#/volume] in Blood
176
1443
1.41
2.77
5.3
6.1
e9/l
0.2
0.2
0.07
158
1284
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
54
348
1.64
2.71
1.8
1.9
—
—
—
0
0
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
23
114
2.08
2.62
1.8
2.4
u/l
39.1
37.9
0.14
23
105
(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
12
44
2.78
2.57
2.0
1.3
—
1.0
—
0
5
(40761511) CBC panel - Blood by Automated count
348
3275
1.84
2.53
11.8
10.1
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
101
761
1.45
2.49
3.6
2.7
e6/l
22.4
156.4
0.89
82
570
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
27
145
1.93
2.49
2.0
2.8
ng/l
108.3
116.2
0.08
19
131
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
21
103
2.10
2.47
1.9
1.6
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
161
1321
1.38
2.44
2.8
2.6
ug/l
97.1
118.0
0.83
154
1221
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
117
910
1.41
2.42
2.8
2.9
ng/l
38.9
31.9
0.22
67
525
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
11
40
2.80
2.39
1.1
1.3
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
18
84
2.20
2.39
1.6
1.8
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
84
617
1.47
2.36
1.3
1.4
g/l
2.6
2.2
0.41
59
398
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
148
1203
1.38
2.35
7.0
7.3
mmol/l
1.2
1.2
2.14
124
1024
(3019225) pH of Specimen
36
217
1.73
2.32
4.5
4.7
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
47
305
1.62
2.31
1.8
2.3
%
23.2
24.0
0.18
41
263
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
63
438
1.53
2.31
3.6
3.2
ng/l
156.7
580.6
1.39
39
324
(3003327) Ova and parasites identified in Stool by Light microscopy
20
99
2.08
2.30
1.3
1.7
—
—
—
0
0
(1616796) Gas panel - Central venous blood
11
41
2.73
2.29
2.1
2.4
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
136
1094
1.38
2.29
2.6
2.2
nmol/l
74.5
73.9
0.11
131
1010
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
6
13
4.67
2.28
1.0
1.2
—
—
—
0
0
(3016921) Smith extractable nuclear Ab [Units/volume] in Serum
15
66
2.33
2.27
1.8
1.2
—
3.9
—
0
10
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
243
2148
1.37
2.23
7.4
7.0
u/l
70.7
76.5
2.40
233
2033
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
91
686
1.43
2.23
2.0
2.1
u/l
134.9
206.7
1.64
91
645
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
132
1063
1.37
2.20
5.6
6.5
mmol/l
1.2
1.2
1.91
124
970
(3004616) Nuclear Ab [Presence] in Serum
8
24
3.38
2.19
1.6
1.3
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
6
14
4.34
2.16
1.0
1.2
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
247
2195
1.37
2.15
3.2
2.9
u/l
37.9
46.8
2.48
236
2090
(3014051) Protein [Presence] in Urine by Test strip
11
43
2.61
2.11
3.5
1.7
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
8
25
3.25
2.10
1.1
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
50
338
1.55
2.08
1.2
1.2
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
5
10
5.05
2.07
1.2
1.3
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
49
330
1.56
2.07
2.5
2.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
138
1129
1.35
2.05
2.0
1.9
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
18
90
2.05
2.04
1.9
2.1
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
24
134
1.84
2.00
6.4
9.0
mmol/l
24.3
24.9
0.28
24
134
(3037467) Urinalysis macro (dipstick) panel - Urine
219
1925
1.33
1.97
4.4
3.7
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
28
165
1.75
1.97
2.0
1.5
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
313
2910
1.45
1.96
4.0
3.7
mmol/l
6.0
5.8
0.67
294
2709
(3024263) Appearance of Synovial fluid
5
11
4.59
1.94
1.4
1.5
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
8
27
3.00
1.94
1.9
2.3
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
39
253
1.60
1.94
2.3
2.1
nmol/l
12.9
13.8
0.35
34
233
(3045424) Erythrocytes [Presence] in Urine
10
39
2.61
1.93
1.4
1.2
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
89
686
1.39
1.91
3.7
2.6
e6/l
0.2
0.4
2.17
67
499
(3021589) Normoblasts [#/volume] in Blood
154
1292
1.33
1.91
8.1
8.3
e9/l
0.0
0.0
0.02
129
1064
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
259
2339
1.34
1.90
3.6
3.3
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
118
954
1.35
1.87
3.4
6.2
inr
1.1
1.2
0.77
42
295
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
310
2884
1.43
1.87
10.9
9.5
ml/min/173m2
89.9
88.2
0.79
265
2337
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
13
59
2.25
1.86
1.5
1.3
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
5
12
4.21
1.83
1.2
1.2
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
18
95
1.94
1.78
1.4
1.1
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
346
3298
1.62
1.76
9.9
8.7
u/l
28.7
28.0
0.27
335
3203
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
314
2937
1.42
1.75
3.9
3.5
mmol/l
1.4
1.3
1.86
294
2769
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
78
598
1.38
1.72
2.4
2.0
mg/l
2.3
2.8
1.60
68
497
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
5
13
3.88
1.72
1.0
1.1
—
—
—
0
0
(3038026) Centromere Ab [Units/volume] in Serum
5
13
3.88
1.72
1.2
1.2
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
187
1630
1.29
1.70
8.0
9.3
e9/l
4.2
4.0
0.66
164
1424
(3025941) Bacteria identified in Stool by Culture
27
166
1.67
1.66
1.3
1.3
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
78
602
1.37
1.66
4.4
4.1
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
7
25
2.83
1.65
1.6
1.6
%
91.8
91.6
—
7
25
(36660697) Celiac disease serology panel - Serum
36
239
1.56
1.65
1.1
1.2
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
323
3049
1.42
1.58
4.2
3.9
mmol/l
4.8
4.8
0.21
302
2890
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
12
57
2.14
1.56
1.6
1.8
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
111
911
1.31
1.56
3.8
3.1
e6/l
63.7
71.9
0.08
87
616
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
322
3040
1.41
1.56
4.1
3.8
mmol/l
1.4
1.5
2.11
302
2870
(3015377) Calcium [Moles/volume] in Serum or Plasma
101
820
1.32
1.53
2.5
3.5
mmol/l
2.4
2.4
0.17
85
738
(44813793)
5
15
3.36
1.53
1.0
1.1
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
35
236
1.53
1.51
1.7
1.8
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
35
237
1.53
1.48
1.7
1.7
—
—
—
0
0
(4094501)
15
80
1.91
1.47
1.0
1.1
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
33
476
0.66
1.45
2.7
2.7
ug/l
0.5
0.7
1.57
18
279
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
289
2693
1.32
1.45
5.0
4.7
mmol/mol
38.7
38.8
0.07
272
2551
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
86
693
1.31
1.37
1.7
1.5
—
—
—
0
0
(4062490)
5
17
2.97
1.36
1.0
1.2
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
5
17
2.97
1.36
3.2
1.2
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
107
890
1.28
1.35
3.6
2.8
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
41
295
1.44
1.31
1.7
1.5
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
324
3083
1.37
1.30
4.4
4.2
mmol/l
3.0
2.9
0.97
303
2905
(3013139) Helicobacter pylori Ag [Presence] in Stool
25
162
1.58
1.29
1.2
1.2
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
5
118
0.42
1.27
3.6
2.3
%
1.0
1.3
—
5
118
(3019309) Folate [Moles/volume] in Red Blood Cells
49
367
1.39
1.26
1.7
1.5
nmol/l
1119.2
1125.3
0.02
40
271
(3025468) Yersinia sp identified in Specimen by Organism specific culture
8
36
2.25
1.25
1.8
1.4
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
8
36
2.25
1.25
1.7
1.4
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
8
37
2.19
1.22
1.7
1.4
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
8
37
2.19
1.22
1.8
1.4
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
8
37
2.19
1.22
1.8
1.4
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
25
166
1.54
1.18
1.1
1.0
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
81
661
1.29
1.18
3.4
3.2
mg/l
82.1
266.8
0.71
54
433
(3050129) First trimester maternal screen panel - Serum or Plasma
10
184
0.53
1.17
1.3
1.5
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
5
20
2.52
1.15
1.0
1.6
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
7
30
2.36
1.13
2.1
1.8
mmol/l
1.5
1.6
—
7
30
(3002385) Erythrocyte distribution width [Ratio]
285
2682
1.26
1.12
13.3
13.1
%
13.4
13.5
1.31
277
2634
(36304419) Bacteria [Presence] in Urine
81
666
1.28
1.12
3.6
2.6
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
19
289
0.64
1.10
1.2
1.4
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
5
21
2.40
1.09
1.0
1.4
mmol/l
5.3
6.7
—
5
21
(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma
5
21
2.40
1.09
1.0
3.2
—
63.4
—
0
8
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
8
41
1.97
1.09
1.0
1.3
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
10
52
1.95
1.07
1.9
1.2
—
—
—
0
0
(4010399)
25
171
1.49
1.05
1.5
1.4
—
—
—
0
0
(3019060) Gas panel - Arterial blood
20
130
1.57
1.05
4.2
7.6
—
—
—
0
0
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
17
106
1.63
1.04
5.1
3.8
mmol/l
23.0
24.0
0.76
17
97
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
17
261
0.63
1.03
1.5
1.5
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
71
582
1.27
1.01
3.5
2.9
kg/l
1.0
1.0
0.40
15
80
(3037121) Protein [Mass/volume] in Urine
15
92
1.66
0.98
3.7
4.4
g/l
0.3
0.3
—
9
43
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
5
23
2.19
0.98
1.0
1.8
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
151
1347
1.20
0.97
3.3
2.9
estimate
0.0
0.0
0.00
29
244
(3019897) Erythrocyte distribution width [Ratio] by Automated count
9
50
1.82
0.97
2.9
1.8
%
13.3
12.9
—
9
50
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
19
125
1.55
0.96
1.8
1.7
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
9
51
1.78
0.95
1.0
1.2
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
69
572
1.25
0.90
3.4
2.9
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
8
42
1.92
0.89
1.3
1.1
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
84
713
1.23
0.89
4.2
3.9
mg/mmol
10.2
10.9
0.05
56
463
(3006184) Hemoglobin [Mass/volume] in Capillary blood
8
43
1.88
0.88
2.8
2.0
g/l
118.8
135.1
—
8
34
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
8
45
1.79
0.84
3.6
1.6
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
18
121
1.51
0.84
1.2
1.3
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
46
571
0.78
0.84
1.7
1.5
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
6
32
1.89
0.82
1.0
1.3
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
90
776
1.21
0.82
3.4
3.0
mmol/l
8.3
8.3
0.04
79
670
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
57
469
1.25
0.80
1.4
1.8
%
1.3
1.4
0.47
48
422
(21494755) Public health laboratory ask at order entry panel
37
469
0.77
0.79
1.4
1.4
—
—
—
0
0
(40758558) Short blood count panel - Blood
81
694
1.21
0.79
6.2
6.7
—
—
—
0
0
(1002224) Polysomnography panel
10
162
0.61
0.79
1.0
1.1
—
—
—
0
0
(4281824)
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
20
140
1.45
0.78
1.8
1.3
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
28
210
1.36
0.76
3.8
3.7
mmol/l
1.8
1.7
0.05
20
165
(3018418) pH of Serum or Plasma
83
717
1.20
0.74
3.7
3.9
ph
7.4
7.4
0.42
21
124
(3019832) Treponema pallidum Ab [Presence] in Serum
37
464
0.78
0.74
1.5
1.7
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
5
25
2.01
0.73
1.0
1.2
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
5
26
1.94
0.71
1.2
1.2
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
7
41
1.72
0.70
1.1
1.2
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
12
77
1.58
0.69
1.2
1.1
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
29
223
1.33
0.69
1.2
1.3
iu/ml
113.1
172.2
—
9
95
(3021601) Nitrite [Presence] in Urine by Test strip
148
1353
1.15
0.67
4.5
4.2
estimate
0.0
0.0
0.00
35
247
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
7
44
1.60
0.65
2.4
1.7
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
5
29
1.73
0.64
1.0
1.8
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
5
29
1.73
0.64
2.2
3.1
—
—
—
0
0
(3012544) pH of Venous blood
28
217
1.31
0.64
3.8
3.7
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
48
400
1.23
0.62
3.6
2.8
mmol/l
2.4
2.4
0.54
39
351
(3009261) Glucose [Presence] in Urine by Test strip
149
1369
1.15
0.62
3.4
3.0
estimate
0.0
0.0
0.00
33
235
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
8
50
1.61
0.61
3.6
3.1
%
55.0
56.0
—
8
50
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
11
163
0.67
0.61
1.6
1.5
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
12
80
1.52
0.60
1.5
1.3
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
7
111
0.62
0.59
2.4
3.5
%
49.0
51.8
—
7
111
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
23
0.00
0.58
0.0
2.2
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
76
668
1.17
0.57
3.8
3.2
estimate
0.0
0.0
0.00
33
244
(3028626) Oxygen [Partial pressure] in Capillary blood
8
55
1.46
0.56
5.5
2.3
kpa
7.8
8.2
—
8
50
(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay
8
55
1.46
0.56
1.1
1.4
u/l
20.5
24.6
—
8
49
(3030981) Hyaline casts [#/volume] in Urine by Automated count
18
133
1.37
0.56
1.4
2.6
e6/l
0.3
0.1
0.66
18
128
(3024522) Salmonella sp identified in Specimen by Organism specific culture
6
37
1.63
0.56
2.0
1.4
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
6
39
1.55
0.53
1.0
1.1
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
6
39
1.55
0.53
2.0
2.0
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
6
97
0.61
0.52
1.7
2.1
%
90.7
91.5
—
6
89
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
47
399
1.20
0.52
3.1
2.4
e6/l
3.0
2.4
0.29
29
210
(3021901) Oxygen saturation in Capillary blood
6
40
1.51
0.52
2.2
1.9
—
—
—
0
0
(3022621) pH of Urine by Test strip
19
144
1.34
0.51
2.7
2.1
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
16
118
1.37
0.51
3.8
3.5
—
—
—
0
0
(40761535) Cells panel - Urine sediment
23
180
1.30
0.51
4.7
3.1
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
37
309
1.22
0.49
2.4
2.6
umol/l
6.1
6.8
0.26
32
260
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
56
488
1.17
0.48
1.6
1.6
pmol/l
484.2
26157824.3
0.76
48
432
(3030905) Polymorphonuclear cells [#/volume] in Blood
7
49
1.44
0.46
3.7
2.9
e9/l
3.1
4.1
—
7
49
(3002256) Pathology report gross observation
41
351
1.19
0.43
1.2
1.3
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
5
31
1.62
0.43
1.0
1.6
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
37
314
1.20
0.43
4.2
3.8
%
31.3
31.3
0.00
28
221
(3024891) Influenza virus A+B Ag [Presence] in Specimen
6
91
0.65
0.43
1.0
1.1
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
15
114
1.33
0.41
2.9
2.8
—
—
—
0
0
(3014043) Spermatozoa Nonprogressive/100 spermatozoa in Semen
0
16
0.00
0.41
0.0
6.2
—
—
—
0
0
(40761995) Spermatozoa Progressive [#/volume] in Semen
0
16
0.00
0.41
0.0
3.1
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
16
0.00
0.41
0.0
2.1
—
—
—
0
0
(40765089) Chromosome analysis panel - Blood by G-banded
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
34
399
0.84
0.41
1.6
1.6
—
—
—
0
0
(3020013) Alkaline phosphatase.intestinal [Enzymatic activity/volume] in Serum or Plasma
0
17
0.00
0.40
0.0
1.5
—
2.0
—
0
7
(3028026) IgM [Mass/volume] in Serum or Plasma
21
169
1.26
0.39
1.2
1.7
g/l
0.9
1.6
1.86
21
152
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
49
431
1.16
0.39
1.5
1.7
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
6
41
1.47
0.36
1.3
2.5
—
—
—
0
0
(3026285) Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma
6
42
1.44
0.35
1.2
1.0
g/l
1.5
1.4
—
6
36
(3047352) Trisomy 18 risk [Likelihood] in Fetus
9
126
0.71
0.35
1.8
1.4
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
9
126
0.71
0.35
1.8
1.4
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
58
643
0.88
0.35
3.7
3.6
%
25.8
21.0
0.79
20
262
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
6
44
1.37
0.34
1.0
1.1
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
84
773
1.11
0.34
3.9
3.9
ug/l
1.3
2.3
1.51
77
702
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
6
87
0.68
0.33
1.3
1.5
—
—
—
0
0
(3000492) Spirometry study
35
304
1.17
0.33
1.3
1.5
—
—
—
0
0
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
6
89
0.67
0.33
7.8
3.1
u/ml
35.3
2503.6
—
6
76
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
115
1079
1.09
0.32
3.4
3.0
—
—
—
0
0
(3020891) Body temperature
11
83
1.34
0.32
3.3
3.6
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
27
230
1.19
0.32
4.1
3.1
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
12
153
0.78
0.31
1.6
1.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
12
153
0.78
0.31
1.6
1.4
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
12
153
0.78
0.31
1.6
1.4
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
12
153
0.78
0.31
1.6
1.4
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
7
100
0.69
0.31
1.4
1.8
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
10
75
1.34
0.30
3.1
2.5
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
47
421
1.13
0.30
3.0
2.3
e6/l
0.2
1.0
4.72
29
229
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
12
93
1.30
0.30
1.8
1.6
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
59
538
1.11
0.29
2.4
3.2
ng/l
896.2
884.7
0.02
47
432
(3043238) Trisomy 21 risk [Likelihood] in Fetus
10
129
0.77
0.28
1.7
1.5
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
9
117
0.76
0.28
1.2
1.4
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
29
253
1.16
0.27
6.8
10.7
mmol/l
0.2
1.1
0.41
20
196
(3028707) Methadone [Presence] in Urine by Screen method
10
77
1.31
0.26
2.9
2.0
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
9
77
1.17
0.24
1.4
2.6
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
70
651
1.09
0.24
2.6
2.1
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
15
124
1.22
0.24
1.7
2.2
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
18
152
1.19
0.24
4.7
3.6
kpa
5.3
5.2
0.46
18
143
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
13
106
1.23
0.23
2.5
2.1
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
60
647
0.91
0.23
1.6
1.7
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
15
178
0.84
0.22
1.0
1.3
—
—
—
0
0
(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3037826) lamoTRIgine [Moles/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.8
—
16.2
—
0
11
(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3014271) Vancomycin [Susceptibility]
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
0
10
0.00
0.21
0.0
2.9
—
—
—
0
0
(4133840)
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3041806) Other cells [#/volume] in Blood by Manual count
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
0
12
0.00
0.21
0.0
2.2
—
67.6
—
0
12
(3006653) Thiamine [Moles/volume] in Blood
0
12
0.00
0.21
0.0
1.2
—
176.6
—
0
12
(3029396) Erythrocyte agglutination [Presence] in Blood
0
12
0.00
0.21
0.0
3.3
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
43
1.16
0.21
1.0
1.0
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
5
43
1.16
0.21
4.0
3.8
—
—
—
0
0
(3045788) Cell count panel - Pleural fluid
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
(3000012) Reticulocyte production index
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
25
280
0.89
0.19
5.8
6.0
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
305
3008
1.07
0.19
11.9
11.6
%
39.9
40.7
0.76
237
2410
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
7
58
1.21
0.18
2.6
1.6
—
—
—
0
0
(3007566) Smooth muscle Ab [Titer] in Serum
10
82
1.23
0.17
1.2
1.2
—
82.0
—
0
5
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
8
72
1.11
0.16
2.6
2.6
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
15
130
1.16
0.16
1.3
1.5
miu/ml
132.7
257.2
—
9
65
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
10
119
0.84
0.15
1.6
1.4
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
25
226
1.11
0.15
1.3
1.7
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
9
81
1.11
0.15
1.6
1.3
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
28
306
0.91
0.15
2.3
2.0
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
97
932
1.05
0.15
1.6
1.5
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
7
87
0.80
0.14
1.0
1.1
—
—
—
0
0
(3000991) Gas panel - Venous blood
22
198
1.12
0.14
8.5
10.0
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
130
1338
0.96
0.13
2.5
2.5
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
17
189
0.89
0.12
2.4
1.6
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
10
116
0.86
0.12
1.4
1.6
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
46
485
0.94
0.11
1.5
2.0
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
13
146
0.89
0.10
1.2
1.6
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
5
45
1.11
0.10
1.4
1.0
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
84
866
0.96
0.09
2.6
2.1
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
5
48
1.04
0.09
1.0
1.0
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
75
775
0.96
0.09
1.7
1.6
mmol/l
1.6
1.4
0.62
62
663
(3034860) Kappa light chains.free [Mass/volume] in Serum
6
57
1.05
0.08
4.5
3.3
mg/l
26.1
59.8
—
6
45
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
6
57
1.05
0.08
4.5
3.2
—
1.2
—
0
6
(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma
6
57
1.05
0.08
4.5
3.3
mg/l
19.1
26.6
—
6
46
(4035726)
24
224
1.08
0.08
1.2
1.4
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
5
62
0.80
0.08
2.0
1.5
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
7
64
1.10
0.08
5.4
1.8
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
7
67
1.05
0.08
1.6
1.8
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
52
540
0.96
0.08
1.8
2.1
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
6
73
0.82
0.07
2.8
4.1
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
26
245
1.07
0.07
2.2
1.9
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
7
81
0.86
0.07
1.3
1.3
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
14
128
1.10
0.07
9.1
12.6
%
95.5
93.9
1.42
14
128
(3041096) Erythrocytes [Presence] in Urine by Automated
83
811
1.03
0.06
2.8
2.7
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
28
294
0.95
0.06
1.6
1.6
—
—
—
0
0
(40768443) Skin Pathology biopsy report
11
100
1.10
0.05
1.1
1.2
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
17
180
0.94
0.04
3.3
3.0
kpa
4.7
4.7
0.06
17
174
(3022313) Gas panel - Capillary blood
12
111
1.08
0.04
5.0
4.0
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
18
190
0.94
0.04
2.1
1.6
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
45
438
1.03
0.04
1.6
1.4
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
71
697
1.02
0.03
4.7
4.5
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
71
698
1.02
0.03
2.5
2.4
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
18
189
0.95
0.03
2.4
1.6
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
40
390
1.03
0.03
1.8
1.8
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
18
188
0.96
0.02
2.1
1.6
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
11
116
0.95
0.00
8.5
17.2
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
14
142
0.99
0.00
2.9
1.6
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
33
329
1.00
0.00
1.5
1.5
—
—
—
0
0
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
16
163
0.98
0.00
1.1
2.3
u/l
17572.4
2369.0
—
5
70
(3016879) Cocaine [Presence] in Urine
17
173
0.98
0.00
2.2
1.6
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
78
777
1.00
0.00
1.6
1.9
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3032567) Hepatitis B virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate
0
8
0.00
0.00
0.0
5.5
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
5
52
0.96
0.00
1.8
1.8
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
8
88
0.91
0.00
1.0
1.1
—
—
—
0
0
(40758990) Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
6
59
1.02
0.00
1.0
1.0
—
—
—
0
0
(3028371) Actinomyces sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3013727) Leukocytes other/100 leukocytes in Blood
0
7
0.00
0.00
0.0
1.6
—
55.1
—
0
7
(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
6
61
0.98
0.00
1.2
1.2
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
6
68
0.88
0.00
1.2
1.3
—
—
—
0
0
(3022689) Creatine [Moles/volume] in Urine
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(40757373) Influenza virus identified in Isolate
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
8
87
0.92
0.00
1.0
1.1
—
—
—
0
0
(3044007) Cell count panel - Peritoneal fluid
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3010464) Parainfluenza virus 1 Ag [Presence] in Specimen
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004446) Plasmodium sp identified in Blood by Light microscopy
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006695) Toxoplasma gondii DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
7
72
0.97
0.00
1.0
1.1
—
—
—
0
0
(3004451) EKG impression Narrative
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3005880) Parainfluenza virus 3 Ag [Presence] in Specimen
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014300) Beta 2 glycoprotein 1 IgM Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
7
72
0.97
0.00
1.0
1.1
—
—
—
0
0
(3025577) Chromium [Mass/volume] in Blood
0
9
0.00
0.00
0.0
2.7
—
2.7
—
0
9
(3026470) Cobalt [Mass/volume] in Blood
0
9
0.00
0.00
0.0
2.7
—
5.0
—
0
9
(3016330) Potassium [Moles/time] in 24 hour Urine
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3000213) Normetanephrine [Moles/time] in 24 hour Urine
0
7
0.00
0.00
0.0
1.3
—
1.8
—
0
7
(3045209) Lutropin/Follitropin [Ratio] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3041293) ARIPiprazole [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3033670) Parathyrin related protein [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032057) Clostridioides difficile [Presence] in Stool
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
(40763634) TCRG gene rearrangements [Presence] in Bone marrow by Molecular genetics method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3036048) Francisella tularensis Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
7
70
1.00
0.00
1.7
1.8
—
—
—
0
0
(3021578) Parainfluenza virus 2 Ag [Presence] in Specimen
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013247) Albumin in CSF/Albumin in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
7.5
—
0
6
(42868417) European tick borne encephalitis virus IgG Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032868) Hemoglobin electrophoresis panel in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4034850)
9
94
0.96
0.00
12.8
7.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_SYNOHYPERTROPH and mortality.

Females

Parameter HR [95% CI] p-value
M13_SYNOHYPERTROPH 0.855 [0.66, 1.11] 0.242
Birth year 0.99 [0.98, 1.0] 0.031

During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 1348 females with M13_SYNOHYPERTROPH died.

Males

Parameter HR [95% CI] p-value
M13_SYNOHYPERTROPH 0.647 [0.51, 0.83] < 0.001
Birth year 0.989 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 1281 males with M13_SYNOHYPERTROPH died.

Mortality risk

Mortality risk for people of age

years, who have M13_SYNOHYPERTROPH.

N-year risk Females Males
1 0.068% 0.126%
5 0.399% 0.722%
10 0.962% 1.892%
15 1.923% 3.781%
20 3.398% 6.383%

Relationships between endpoints

Index endpoint: M13_SYNOHYPERTROPH – Synovial hypertrophy, not elsewhere classified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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