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Systemic lupus erythematosus


systemic lupus erythematosus: An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.

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Endpoint definition

Endpoint definition steps


Phenotype data


1. Apply sex-specific rule



2. Check conditions



3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M32
  • Hospital discharge: ICD-9 7100
  • Hospital discharge: ICD-8 7431
  • Cause of death: ICD-10 M32
  • Cause of death: ICD-9 7100
  • Cause of death: ICD-8 7431

2 out of 7 registries used, show all original rules.


4. Check minimum number of events



5. Include endpoints



6. Filter based on genotype QC (FinnGen only)


Control definitions (FinnGen only)

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30-M36
Name in latin Lupus erythematosus disseminatus (LED)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics


This endpoint is excluded from FinRegistry analyses (omitted endpoint).


Key figures

All Female Male
Number of individuals 1198 991 207
Unadjusted period prevalence (%) 0.34 0.39 0.10
Median age at first event (years) 47.24 45.90 53.64


Age distribution of first events


Year distribution of first events


Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: M13_SLE – Systemic lupus erythematosus

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).