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Systemic lupus erythematosus

M13_SLE

systemic lupus erythematosus: An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M32
  • Hospital discharge: ICD-9 7100
  • Hospital discharge: ICD-8 7431
  • Cause of death: ICD-10 M32
  • Cause of death: ICD-9 7100
  • Cause of death: ICD-8 7431

2 out of 7 registries used, show all original rules.

1355

4. Check minimum number of events

None

1355

5. Include endpoints

None

1355

6. Filter based on genotype QC (FinnGen only)

1355

Control definitions (FinnGen only)

Control exclude
M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M30-M36
Name in latin
Lupus erythematosus disseminatus (LED)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1355 1118 237
Unadjusted period prevalence (%) 0.33 0.38 0.10
Median age at first event (years) 47.08 45.61 53.98

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1244
Matched controls
12440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P01BA02
ATC
hydroxychloroquine; oral
67.9
323.0
886
437
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
39.2
323.0
844
634
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
4503599627370496.0
323.0
1028
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
314.3
288
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
1655.5
280.1
262
*
L04AX01
ATC
azathioprine; systemic
28.6
258.7
361
175
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
+∞
245.1
227
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
229.5
213
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
14.9
207.7
371
344
H02AB06
ATC
prednisolone; systemic
7.0
206.0
958
4025
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
328.2
196.2
194
7
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
+∞
185.1
173
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
9.9
169.0
376
521
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.5
168.4
764
2802
L04AA06
ATC
mycophenolic acid; systemic
44.5
160.6
199
53
L93.0
ICD-10 Finland
Discoid lupus erythematosus
122.2
150.1
160
15
M32
ICD-10 Finland
Systemic lupus erythematosus
+∞
146.8
138
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
132.7
125
*
H02AB07
ATC
prednisone; oral
5.6
119.9
411
999
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
8.1
111.3
272
413
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
8.0
104.4
257
392
M05BA04
ATC
alendronic acid; oral
7.2
103.1
275
472
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.7
102.4
721
3375
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
100.4
95
*
73410
ICD-8 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
956.1
92.0
89
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.8
88.2
279
590
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
9.7
75.2
160
186
L88
ICPC
Rheumatoid/seropositive arthritis
9.3
66.7
145
174
R50.9
ICD-10 Finland
Fever, unspecified
4.1
66.2
299
893
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
6.9
61.6
164
269
C08CA05
ATC
nifedipine; systemic
6.3
60.0
170
303
H02AB04
ATC
methylprednisolone; systemic
3.4
53.9
304
1071
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.5
52.9
206
525
L04AD01
ATC
ciclosporin; systemic
14.1
52.4
91
69
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
49.4
461
2250
L04AA01
ATC
[U] ciclosporin; systemic
16.5
48.6
79
51
ZX120
NOMESCO Finland
Intravenous
4.2
48.1
204
561
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
20.0
47.6
72
38
C03CA01
ATC
furosemide; systemic
2.8
47.4
387
1736
A02BC02
ATC
pantoprazole; systemic
2.5
45.8
898
6385
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
45.4
240
795
XX9XE
NOMESCO Finland
Other ultrasound examination
23.6
45.3
65
29
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
453.3
44.5
44
*
G05.8*M32.1
ICD-10 Finland
Encephalitis in systemic lupus erythematosus
+∞
44.0
42
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.3
43.5
624
3754
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
42.6
329
1412
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
10.4
42.5
85
87
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.9
40.6
185
538
P01BA01
ATC
chloroquine; systemic
36.1
40.6
52
15
E0000UV
ATC
NA
2.2
39.0
591
3584
J01MA12
ATC
levofloxacin; systemic
2.8
38.8
290
1211
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.7
38.6
307
1330
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
38.6
327
1470
H04.10
ICD-10 Finland
Dry eye syndrome
3.4
38.2
208
696
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.7
37.0
176
529
D68.8
ICD-10 Finland
Other specified coagulation defects
14.1
36.1
62
46
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.7
34.4
274
1179
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
34.0
255
1057
L93.1
ICD-10 Finland
Subacute cutaneous lupus erythematosus
123.5
33.8
36
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.5
33.7
174
557
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
+∞
33.5
32
*
J01FF01
ATC
clindamycin; systemic
2.3
32.7
405
2189
D07AB08
ATC
desonide; topical
3.1
32.5
198
715
N02AX02
ATC
tramadol; systemic, rectal
2.1
31.5
561
3539
G73.7*M32.1
ICD-10 Finland
Myopathy in systemic lupus erythematosus
+∞
31.4
30
*
M05BA07
ATC
risedronic acid; oral
6.5
30.5
81
131
J99.1*M32.1
ICD-10 Finland
Respiratory disorders in systemic: lupus erythematosus
+∞
30.3
29
*
M13.9
ICD-10 Finland
Arthritis, unspecified
3.8
30.0
134
380
M35.3
ICD-10 Finland
Polymyalgia rheumatica
11.0
29.2
56
53
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
28.6
325
1667
B01AA03
ATC
warfarin; systemic
2.6
28.5
237
1033
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
6.9
28.4
72
109
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.3
27.3
151
504
SBA10
NOMESCO Finland
Measurement of excretion of saliva
15.7
27.0
44
29
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.4
26.8
101
245
J01MA02
ATC
ciprofloxacin; systemic
2.0
26.1
489
3081
J01FA06
ATC
roxithromycin; oral
1.9
25.9
566
3768
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.5
25.9
69
112
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.3
25.9
271
1329
D07AC01
ATC
betamethasone; topical
2.0
25.5
468
2916
A02BC03
ATC
lansoprazole; oral
2.0
25.5
407
2401
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.9
25.5
86
186
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.6
24.8
117
346
J05AB11
ATC
valaciclovir; oral
2.5
24.6
219
986
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
24.5
540
3584
R06.0
ICD-10 Finland
Dyspnoea
2.1
24.5
334
1841
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
24.4
228
1052
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
22.5
24.4
35
16
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.5
24.3
90
214
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.3
24.3
93
229
XPX04
NOMESCO Finland
Angioscopy
29.8
24.2
32
11
J05AB01
ATC
aciclovir; systemic
2.1
24.1
323
1767
E000001
ATC
NA
2.2
24.0
304
1617
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
8.5
24.0
53
65
H26.3
ICD-10 Finland
Drug-induced cataract
26.0
24.0
33
13
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
24.0
23
*
B01AB05
ATC
enoxaparin; parenteral
2.0
23.0
404
2452
B07.9
ICD-10 Finland
Verruca simplex
4.8
22.9
79
175
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
11.7
22.8
42
37
A02BC01
ATC
omeprazole; systemic
2.0
22.6
377
2243
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
22.4
125
419
R4120
NOMESCO Finland
Occupational therapy
3.4
22.3
113
354
R4110
NOMESCO Finland
Physiotherapy
2.0
22.2
357
2090
I73.0
ICD-10 Finland
Raynaud syndrome
8.6
22.0
48
58
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.3
21.7
83
204
L93.2
ICD-10 Finland
Other local lupus erythematosus
223.8
21.7
22
*
L01AA01
ATC
cyclophosphamide; systemic
26.9
21.4
29
11
M05BB03
ATC
alendronic acid and colecalciferol; oral
5.7
21.4
62
113
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
+∞
20.9
20
*
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
20.9
20
*
73491
ICD-8 Finland
Diffuse diseases of connective tissue, Collagenosis NUD
+∞
20.9
20
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.5
20.9
176
765
C08CA01
ATC
amlodipine; oral
1.9
20.9
400
2488
J01DB01
ATC
cefalexin; oral
2.0
20.6
1032
8807
M25.5
ICD-10 Finland
Pain in joint
1.9
20.6
398
2481
M05BX04
ATC
denosumab; parenteral
3.8
20.5
91
256
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.4
20.4
104
327
M34.1
ICD-10 Finland
CR(E)ST syndrome
+∞
19.8
19
*
D07AC13
ATC
mometasone; topical
1.9
19.8
384
2391
A07AA02
ATC
nystatin; oral
3.2
19.7
106
348
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.1
19.5
62
126
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
4.8
19.4
65
140
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
19.3
164
715
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
19.2
334
1998
N03AX16
ATC
pregabalin; oral
1.9
19.1
319
1878
NF1AA
NOMESCO Finland
Hip X-ray examination
2.8
19.0
127
482
UJF30
NOMESCO Finland
Ileoscopy through colon
2.6
18.9
149
623
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
18.8
173
786
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
5.6
18.7
55
102
1XC02
NOMESCO Finland
NA
12.5
18.6
33
27
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
6.4
18.6
49
79
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
192.8
18.6
19
*
L04AA13
ATC
leflunomide; oral
4.8
18.5
62
134
L99
ICPC
Musculoskeletal disease other
6.0
18.4
51
88
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
30.5
18.4
24
8
N32.9
ICD-10 Finland
Bladder disorder, unspecified
25.5
18.3
25
10
318
Kela drug reimbursment
Teriparatide
22.1
18.2
26
12
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.9
18.1
117
433
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.8
17.9
60
130
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.9
17.8
115
424
J01DA01
ATC
[U] cefalexin; systemic
1.7
17.8
799
6374
B02.9
ICD-10 Finland
Zoster without complication
3.2
17.8
95
310
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
17.8
227
1197
XW000
NOMESCO Finland
Bone marrow biopsy
3.9
17.3
72
192
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.2
17.3
95
317
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.2
17.1
93
308
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.7
17.0
75
211
D07AB02
ATC
hydrocortisone butyrate; topical
1.8
17.0
370
2371
A02BC05
ATC
esomeprazole; systemic
1.7
16.9
525
3750
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
6.4
16.8
44
71
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.6
16.8
78
229
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
16.7
125
507
I32.8*M32.1
ICD-10 Finland
Pericarditis (in) systemic lupus erythematosus
+∞
16.7
16
*
7109X
ICD-9 Finland
Diffuse diseases of connective tissue, Unspecified diffuse connective tissue disease
+∞
16.7
16
*
M34.0
ICD-10 Finland
Progressive systemic sclerosis
+∞
16.7
16
*
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
16.7
16
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
16.7
16
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.4
16.7
152
683
A07EC01
ATC
sulfasalazine; oral, rectal
2.7
16.7
123
493
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
4.7
16.5
56
123
I30.9
ICD-10 Finland
Acute pericarditis, unspecified
18.2
16.5
25
14
M35.7
ICD-10 Finland
Hypermobility syndrome
18.2
16.5
25
14
R51.80
ICD-10 Finland
Headache
2.1
16.5
210
1104
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
5.4
16.5
49
93
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
16.4
80
244
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
7.0
16.3
40
59
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.6
16.3
124
505
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.3
16.2
61
149
L95
ICPC
Osteoporosis
4.2
16.2
62
154
N02BE01
ATC
paracetamol; systemic, rectal
1.9
16.1
1064
9386
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.8
16.1
106
398
TNG10
NOMESCO Finland
Puncture of knee
9.1
16.0
33
37
A46
ICD-10 Finland
Erysipelas
2.2
16.0
169
817
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
15.9
76
228
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.5
15.9
74
218
N02AA05
ATC
oxycodone; systemic
2.2
15.8
168
814
N06AA09
ATC
amitriptyline; systemic
2.3
15.8
154
716
NH3EA
NOMESCO Finland
Feet X-ray examination with load
5.3
15.7
48
94
J01MA14
ATC
moxifloxacin; systemic
2.5
15.7
125
525
G73.7
ICD-10 Finland
Myopathy in other diseases classified elsewhere
+∞
15.7
15
*
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
+∞
15.7
15
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.3
15.6
47
91
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
15.6
167
815
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.4
15.5
46
87
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.8
15.5
52
113
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.2
15.5
161
771
B99
ICD-10 Finland
Other and unspecified infectious diseases
6.4
15.4
40
64
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
15.4
156
740
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
15.3
172
856
UJF32
NOMESCO Finland
Coloscopy
1.8
15.2
310
1931
N03AX12
ATC
gabapentin; oral
2.0
15.2
216
1186
QC6S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in hand
45.6
15.1
18
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
15.0
456
3207
Z49.1
ICD-10 Finland
Extracorporeal dialysis
7.7
14.9
34
45
WZA10
NOMESCO Finland
Long statement of health and health related matters
6.1
14.9
40
67
XQ848
NOMESCO Finland
Dermatological photography
4.6
14.9
52
118
6BA02
NOMESCO Finland
NA
57.4
14.8
17
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
7.0
14.7
36
53
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
7.0
14.7
36
53
M81.4
ICD-10 Finland
Drug-induced osteoporosis
25.4
14.7
20
8
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.2
14.7
79
260
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
14.6
14
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.7
14.6
411
2821
Z94.0
ICD-10 Finland
Kidney transplant status
8.6
14.5
31
37
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
7.7
14.5
33
44
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
6.1
14.4
39
66
D07AD01
ATC
clobetasol; topical
2.0
14.4
214
1193
N18.0
ICD-10 Finland
End-stage renal disease
8.0
14.4
32
41
A11CC03
ATC
alfacalcidol; systemic
5.2
14.3
44
87
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.3
14.3
43
83
B03XA02
ATC
darbepoetin alfa; parenteral
5.8
14.3
40
71
H05AA02
ATC
teriparatide; parenteral
19.4
14.3
21
11
M05BA01
ATC
etidronic acid; systemic
13.6
14.2
24
18
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
14.2
560
4198
ZX108
NOMESCO Finland
Inhalation
14.6
14.1
23
16
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.1
14.0
79
268
C08CA02
ATC
felodipine; oral
2.5
13.9
116
498
M05BA06
ATC
ibandronic acid; systemic
4.7
13.8
47
104
PAW37
NOMESCO Finland
Biopsy of temporal artery
24.1
13.8
19
8
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
13.7
490
3573
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
13.7
217
1237
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
13.6
99
394
127
Kela drug reimbursment
Transplant complication
6.7
13.6
34
52
L93
ICD-10 Finland
Lupus erythematosus
76.0
13.6
15
*
G73.7*M35.0
ICD-10 Finland
Myopathy in sicca syndrome [Sjögren]
+∞
13.6
13
*
N16.4*M32.1
ICD-10 Finland
Renal tubulo-interstitial disorders in systemic lupus erythematosus
+∞
13.6
13
*
WW200
NOMESCO Finland
Immunization
4.5
13.6
48
111
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.3
13.5
125
567
L01BB01
ATC
NA
34.4
13.5
17
5
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.4
13.4
113
489
D02BB01
ATC
betacarotene; oral
18.5
13.4
20
11
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
13.3
142
689
ZX140
NOMESCO Finland
Intra articular
10.6
13.3
25
24
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.5
13.2
46
105
A02BA02
ATC
ranitidine; systemic
1.8
13.1
238
1422
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
13.1
129
602
M79.7
ICD-10 Finland
Fibromyalgia
3.2
13.1
68
219
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.2
12.9
135
649
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
4.2
12.9
48
117
ZXA00
NOMESCO Finland
Right side
1.7
12.9
320
2104
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
12.8
447
3224
WX002
NOMESCO Finland
Sedation and analgesia
1.8
12.8
240
1448
M01AH02
ATC
rofecoxib; oral
2.0
12.8
176
951
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
32.4
12.6
16
5
M33.2
ICD-10 Finland
Polymyositis
+∞
12.5
12
*
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
+∞
12.5
12
*
F02.89*M32.8
ICD-10 Finland
Dementia in systemic lupus erythematosus
+∞
12.5
12
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
12.5
115
519
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
24.6
12.5
17
7
NH3AE
NOMESCO Finland
Feet ultrasound examination
24.6
12.5
17
7
JN4BD
NOMESCO Finland
Extensive body CT
2.2
12.5
130
624
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.8
12.4
52
141
ULA02
NOMESCO Finland
Kolposcopy
2.1
12.4
155
803
WX110
NOMESCO Finland
Local anesthesy
1.6
12.3
832
7008
I50.9
ICD-10 Finland
Heart failure, unspecified
2.3
12.3
119
550
TAB00
NOMESCO Finland
Lumbar puncture
2.9
12.3
73
258
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
9.1
12.3
25
28
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.6
12.3
377
2627
L28
ICPC
Limited function/disability (L)
1.9
12.2
186
1045
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
5.7
12.1
34
61
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
4.7
12.1
40
87
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.2
12.1
63
204
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.6
12.0
89
358
TK800
NOMESCO Finland
Hemodialysis
4.8
12.0
39
83
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
9.4
12.0
24
26
N18.8
ICD-10 Finland
Other chronic renal failure
4.6
12.0
41
92
TGC00
NOMESCO Finland
Bronchial lavation
4.6
12.0
41
92
69540
ICD-8 Finland
Erythematous condition, Lupus erythematosus
47.1
11.9
14
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.4
11.8
98
422
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
10.6
11.8
22
21
S76
ICPC
Skin infection other
2.9
11.8
70
248
J01AA02
ATC
doxycycline; systemic
1.6
11.8
952
8324
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
11.7
146
755
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.5
11.7
53
154
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.2
11.7
60
192
5BA08
NOMESCO Finland
NA
16.6
11.7
18
11
J02AC01
ATC
fluconazole; systemic
1.5
11.7
571
4439
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
2.0
11.6
152
804
XF404
NOMESCO Finland
Ambulatory ECG
2.3
11.6
110
507
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
11.5
545
4202
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.8
11.5
48
130
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.9
11.5
71
256
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.7
11.3
78
301
S97
ICPC
Chronic ulcer skin
3.0
11.3
65
225
H02AB09
ATC
hydrocortisone; systemic
4.5
11.3
39
89
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
7.4
11.3
26
36
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.4
11.2
33
63
D07AA02
ATC
hydrocortisone; topical
1.9
11.2
175
988
XG410
NOMESCO Finland
Flow-volume spirometry
3.2
11.2
58
187
ZXA05
NOMESCO Finland
Left side
1.7
11.2
293
1945
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
8.1
11.1
24
30
SPAT1263
SPAT
Sampling
1.5
11.1
501
3812
C02CA01
ATC
prazosin; oral
7.2
11.1
26
37
SAA04
NOMESCO Finland
Special inverstigation of mouth
2.7
11.1
76
292
137
Kela drug reimbursment
Uraemia requiring dialysis
8.7
11.0
23
27
AA1AD
NOMESCO Finland
CT of head and brain
1.7
11.0
257
1653
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
5.5
10.9
31
57
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
7.9
10.9
24
31
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.3
10.9
102
466
A41.9
ICD-10 Finland
Sepsis, unspecified
3.7
10.9
46
127
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.2
10.8
112
537
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.4
10.8
89
382
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.9
10.8
64
227
P01AB01
ATC
metronidazole; oral, rectal
1.5
10.7
513
3944
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.5
10.7
84
349
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
21.7
10.7
15
7
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.0
10.7
141
749
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
10.6
194
1153
M13.0
ICD-10 Finland
Polyarthritis, unspecified
6.4
10.6
27
43
M79.6
ICD-10 Finland
Pain in limb
1.5
10.6
430
3183
C09AA02
ATC
enalapril; systemic
1.8
10.6
203
1227
TEA00
NOMESCO Finland
Biopsy of lip
9.3
10.5
21
23
A12BA01
ATC
potassium chloride; oral
3.1
10.5
56
185
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.3
10.5
52
163
205
Kela drug reimbursment
Chronic hypertension
1.7
10.5
272
1799
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
10.5
275
1826
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
5.5
10.5
30
56
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
10.5
220
1371
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
+∞
10.4
10
*
L94.8
ICD-10 Finland
Other specified localized connective tissue disorders
+∞
10.4
10
*
7108X
ICD-9 Finland
Diffuse diseases of connective tissue, Other specified diffuse diseases of connective tissue
+∞
10.4
10
*
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
10.4
10
*
N08.5*M30.0
ICD-10 Finland
Glomerular disorders in polyarteritis nodosa
+∞
10.4
10
*
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
10.4
10
*
C07AB07
ATC
bisoprolol; oral
1.5
10.4
484
3692
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.5
10.4
48
143
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.4
10.3
91
403
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
10.3
171
984
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
10.3
171
986
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
4.2
10.3
38
93
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
9.7
10.3
20
21
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
10.3
354
2518
WX203
NOMESCO Finland
Infraclavicular plexus blockade
4.0
10.3
40
103
A01
ICPC
Pain general/multiple sites
2.2
10.3
103
486
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
3.5
10.2
47
139
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.5
10.2
78
319
N30.0
ICD-10 Finland
Acute cystitis
1.8
10.2
179
1052
XA800
NOMESCO Finland
Neuropsychological investigation
3.0
10.2
59
206
M01AE02
ATC
naproxen; oral, rectal
1.5
10.1
689
5686
R03AC02
ATC
salbutamol; inhalant
1.5
10.1
641
5210
R05
ICD-10 Finland
Cough
1.7
10.1
239
1537
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
10.1
327
2287
A01AB10
ATC
natamycin; local oral
3.5
10.0
46
136
B05DA
ATC
Isotonic solutions
9.2
10.0
20
22
K90.0
ICD-10 Finland
Coeliac disease
3.2
10.0
52
169
L84
ICD-10 Finland
Corns and callosities
3.1
9.9
53
176
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.4
9.9
47
143
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
9.9
432
3242
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
9.8
132
702
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
4.6
9.8
33
74
R13
ICD-10 Finland
Dysphagia
2.4
9.8
85
375
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.3
9.7
35
84
D01AE16
ATC
amorolfine; topical
1.9
9.7
139
762
N32.1
ICD-10 Finland
Vesicointestinal fistula
55.4
9.7
11
*
C02KX01
ATC
bosentan; oral
55.4
9.7
11
*
A12AA04
ATC
calcium carbonate; oral
4.9
9.6
30
62
Z49.2
ICD-10 Finland
Other dialysis
8.4
9.6
20
24
K11.2
ICD-10 Finland
Sialoadenitis
3.2
9.6
49
158
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.9
9.6
38
100
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
9.5
188
1146
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.5
9.5
43
126
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.5
9.5
32
72
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.3
9.5
90
413
D02AE01
ATC
carbamide; topical
2.3
9.5
90
413
NDB78
NOMESCO Finland
Prosthetic replacement of several of finger or metacarpal
30.3
9.4
12
*
A28
ICPC
Limited function/disability NOS
1.9
9.4
142
791
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
9.4
9
*
M35.2
ICD-10 Finland
Behçet disease
+∞
9.4
9
*
R06AE07
ATC
cetirizine; oral
1.5
9.4
547
4348
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
21.9
9.4
13
6
N05CF01
ATC
zopiclone; oral
1.5
9.4
367
2680
WX320
NOMESCO Finland
Spinalanesthesy
1.6
9.3
258
1727
N02AC04
ATC
dextropropoxyphene; oral
3.1
9.3
50
167
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
9.3
189
1161
GD1AD
NOMESCO Finland
Thorax CT examination
3.0
9.3
53
182
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
10.8
9.3
17
16
B05DB
ATC
Hypertonic solutions
10.8
9.3
17
16
A01AB04
ATC
amphotericin B; local oral
2.5
9.3
70
287
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
9.3
67
269
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.9
9.2
133
727
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.9
9.2
137
761
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
9.2
308
2166
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.4
9.1
80
352
A63.0
ICD-10 Finland
Anogenital (venereal) warts
2.8
9.1
57
209
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.1
9.1
104
520
E000006
ATC
NA
2.2
9.1
97
470
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
5.6
9.1
25
45
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
15.7
9.0
14
9
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.6
9.0
65
260
D06BX01
ATC
metronidazole; topical
1.9
9.0
141
798
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.8
9.0
56
204
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.8
9.0
170
1023
D02AX
ATC
Other emollients and protectives
2.9
9.0
53
189
N03AF02
ATC
oxcarbazepine; oral
3.1
8.9
47
155
EBA10
NOMESCO Finland
Surgical removal of tooth
1.9
8.9
140
788
RJ421
NOMESCO Finland
NA
18.7
8.9
13
7
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.7
8.9
61
237
SPAT1325
SPAT
Vaccination
1.5
8.9
361
2651
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
5.8
8.9
24
42
E000007
ATC
NA
2.3
8.9
82
373
R53
ICD-10 Finland
Malaise and fatigue
1.6
8.9
225
1471
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
8.9
204
1301
SPAT1229
SPAT
Assessment of need for aid
2.2
8.8
84
388
A01AC01
ATC
triamcinolone; local oral
4.3
8.8
31
73
E000002
ATC
NA
1.8
8.8
148
853
WX892
NOMESCO Finland
Monitored bed care
2.3
8.7
81
370
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
3.6
8.7
37
104
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
8.7
157
928
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.3
8.7
77
343
B01AB04
ATC
dalteparin; parenteral
2.5
8.6
65
265
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
2.4
8.6
71
305
R76.0
ICD-10 Finland
Raised antibody titre
11.7
8.6
15
13
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
11.7
8.6
15
13
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
16.4
8.6
13
8
J01MA06
ATC
norfloxacin; oral
1.7
8.5
176
1087
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
8.5
202
1296
I20.90
ICD-10 Finland
Angina pectoris, unspecified
3.5
8.5
38
111
WX204
NOMESCO Finland
Axillary plexus blockaced
3.1
8.5
44
144
L17
ICPC
Foot/toe symptom/complaint
1.5
8.5
289
2035
RJ511
NOMESCO Finland
NA
27.7
8.5
11
*
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
27.7
8.5
11
*
C07AB02
ATC
metoprolol; systemic
1.7
8.5
206
1332
C02DE02
ATC
NA
6.0
8.5
22
37
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
8.5
118
640
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.7
8.4
27
58
L71.8
ICD-10 Finland
Other rosacea
4.7
8.4
27
58
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
4.7
8.4
27
58
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.3
8.4
76
342
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.8
8.4
20
30
ZZA00
NOMESCO Finland
Split skin graft
3.9
8.4
33
87
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
8.3
8
*
7100A
ICD-10 Finland
NA
+∞
8.3
8
*
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
8.3
8
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
8.3
252
1725
H26.2
ICD-10 Finland
Complicated cataract
5.3
8.3
24
46
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
8.6
8.3
17
20
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.7
8.3
180
1127
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
8.3
322
2333
J01EA01
ATC
trimethoprim; systemic
1.5
8.3
318
2301
WW500
NOMESCO Finland
Blood transfusion
2.8
8.3
52
191
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.9
8.2
114
616
A08
ICPC
Swelling
2.9
8.2
48
170
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.7
8.2
53
200
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
2.8
8.2
49
177
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.2
8.2
77
355
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.1
8.2
95
478
Z49.0
ICD-10 Finland
Preparatory care for dialysis
5.4
8.2
23
43
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.3
8.2
71
313
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
8.1
254
1752
X58
ICD-10 Finland
Exposure to other specified factors
1.8
8.1
147
872
M01CB01
ATC
sodium aurothiomalate; parenteral
4.5
8.1
27
61
R80
ICD-10 Finland
Isolated proteinuria
6.9
8.1
19
28
3AC01
NOMESCO Finland
NA
5.1
8.0
24
48
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
22.2
8.0
11
5
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.4
8.0
68
298
S01KA02
ATC
hypromellose; ophthalmic
3.7
8.0
33
91
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.3
8.0
73
332
L50.9
ICD-10 Finland
Urticaria, unspecified
2.7
7.9
54
208
TQW80
NOMESCO Finland
Local dermatologic skincare
3.3
7.9
38
118
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
6.6
7.9
19
29
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
7.9
456
3579
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
5.4
7.9
22
41
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
4.5
7.8
26
59
B01AC04
ATC
clopidogrel; oral
1.8
7.8
131
760
L71.9
ICD-10 Finland
Rosacea, unspecified
3.4
7.7
35
104
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
7.7
278
1977
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.3
7.7
37
115
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
15.1
7.7
12
8
D06BB04
ATC
podophyllotoxin; topical
2.3
7.7
69
311
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
4.1
7.7
28
69
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
6.0
7.7
20
34
H20.1
ICD-10 Finland
Chronic iridocyclitis
6.0
7.7
20
34
XCK00
NOMESCO Finland
Perimetry
2.2
7.7
78
370
H26.4
ICD-10 Finland
After-cataract
2.0
7.7
92
471
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
2.0
7.7
96
500
Z50.1
ICD-10 Finland
Other physical therapy
2.2
7.6
71
327
RT272
NOMESCO Finland
NA
11.9
7.6
13
11
RT274
NOMESCO Finland
NA
25.2
7.6
10
*
S18
ICPC
Laceration/cut
1.4
7.6
439
3443
6489X
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Other current conditions classifiable elsewhere
10.1
7.5
14
14
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.2
7.5
38
123
M01AH01
ATC
celecoxib; oral (coxibs)
1.6
7.5
211
1416
N05BA01
ATC
diazepam; systemic, rectal
1.7
7.5
150
915
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
7.5
247
1720
L04AB01
ATC
etanercept; parenteral
4.5
7.5
25
57
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.4
7.5
62
270
C07AG02
ATC
carvedilol; oral
2.4
7.4
61
262
WZA90
NOMESCO Finland
Other doctors statement
1.5
7.4
260
1836
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
7.4
153
944
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.3
7.4
26
62
RT172
NOMESCO Finland
NA
80.6
7.4
8
*
N04.2
ICD-10 Finland
Nephrotic syndrome, diffuse membranous glomerulonephritis
80.6
7.4
8
*
M35
ICD-10 Finland
Other systemic involvement of connective tissue
80.6
7.4
8
*
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.8
7.4
47
174
RJ410
NOMESCO Finland
NA
13.4
7.4
12
9
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.2
7.4
36
114
V03AE02
ATC
sevelamer; oral
8.4
7.3
15
18
6954B
ICD-9 Finland
Erythematous conditions, Lupus erythematosus[LUPUS ERYTHEMATOSUS DISCOIDES DISSEMINATUS]
+∞
7.3
7
*
74310
ICD-8 Finland
Other congenital anomalies of nervous system, Microcephalus
+∞
7.3
7
*
4AA26
NOMESCO Finland
NA
+∞
7.3
7
*
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
7.3
7
*
I68.2*M32.1
ICD-10 Finland
Cerebral arteritis in systemic lupus erythematosus
+∞
7.3
7
*
R76.8
ICD-10 Finland
Other specified abnormal immunological findings in serum
+∞
7.3
7
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.7
7.3
170
1084
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.8
7.2
119
683
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
7.2
144
881
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.0
7.2
84
427
N04.0
ICD-10 Finland
Nephrotic syndrome, minor glomerular abnormality
30.2
7.2
9
*
WW400
NOMESCO Finland
Plasmaferesis
20.1
7.1
10
5
A99
ICPC
Disease/condition unspecnature/site
2.0
7.1
88
457
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
6.6
7.1
17
26
K07.60
ICD-10 Finland
Snapping jaw
2.2
7.1
72
343
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
7.1
333
2503
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
5.7
7.1
19
34
LCA06
NOMESCO Finland
Biopsy of endometrium
1.6
7.1
170
1096
SBB10
NOMESCO Finland
Teeth copy
2.1
7.1
74
358
A01AB09
ATC
miconazole; local oral
1.8
7.1
112
635
RJ411
NOMESCO Finland
NA
10.1
7.0
13
13
UKC02
NOMESCO Finland
Cystoscopy
1.7
7.0
136
821
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.0
7.0
89
467
NG1DA
NOMESCO Finland
X-ray of knees
3.9
7.0
27
71
C01CA24
ATC
epinephrine; parenteral
2.0
7.0
82
415
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.8
6.9
115
663
ZZH31
NOMESCO Finland
Bone allograft, small pieces
6.4
6.9
17
27
B03XA01
ATC
erythropoietin; parenteral
6.4
6.9
17
27
H25.0
ICD-10 Finland
Senile incipient cataract
2.3
6.9
63
284
AN1
HP
Coronary angiography
1.9
6.9
96
518
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.8
6.9
111
631
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.5
6.9
30
87
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
7.6
6.9
15
20
J31.0
ICD-10 Finland
Chronic rhinitis
1.9
6.9
94
506
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.8
6.9
42
155
H53.1
ICD-10 Finland
Subjective visual disturbances
2.0
6.9
80
407
TQW40
NOMESCO Finland
Remowal of suture of skin
2.0
6.9
88
464
R1250
NOMESCO Finland
Evaluation of functional capability
3.2
6.8
33
104
UJD02
NOMESCO Finland
Gastroscopy
2.3
6.8
58
256
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.8
6.8
114
659
M48.0
ICD-10 Finland
Spinal stenosis
1.8
6.8
119
696
M81.8
ICD-10 Finland
Other osteoporosis
6.7
6.8
16
24
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
6.8
81
413
R05
ICPC
Cough
1.5
6.8
253
1811
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
5.1
6.8
20
40
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.3
6.8
32
99
NDL52
NOMESCO Finland
Tenosynovectomy of hand
6.1
6.8
17
28
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.4
6.8
31
94
A02BA04
ATC
nizatidine; systemic
1.9
6.8
91
487
K59.1
ICD-10 Finland
Functional diarrhoea
2.3
6.8
62
282
2873A
ICD-9 Finland
Purpura and other haemorrhagic conditions, Primary thrombocytopenia[PURPURA THROMBOCYTOPENICA IDIOPATHICA (ITP)]
40.3
6.8
8
*
I77.6
ICD-10 Finland
Arteritis, unspecified
40.3
6.8
8
*
R4190
NOMESCO Finland
Nutritional therapy
2.7
6.8
44
168
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
3.0
6.8
36
122
D06BB10
ATC
imiquimod; topical
2.3
6.7
59
263
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.3
6.7
60
272
RT271
NOMESCO Finland
NA
22.6
6.7
9
*
RJ412
NOMESCO Finland
NA
22.6
6.7
9
*
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.8
6.7
116
679
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
6.7
147
922
C01DA14
ATC
isosorbide mononitrate; oral
1.8
6.7
114
663
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
6.7
82
425
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
5.2
6.6
19
37
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
2.5
6.6
50
207
Z71.8
ICD-10 Finland
Other specified counselling
1.5
6.6
273
1996
GD2SN
NOMESCO Finland
Lung ventilation SPECT
7.9
6.6
14
18
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
7.9
6.6
14
18
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
2.4
6.6
54
235
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.2
6.6
61
280
LEB00
NOMESCO Finland
Biopsy of vagina
3.4
6.6
30
91
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
2.6
6.6
46
182
M79.1
ICD-10 Finland
Myalgia
1.6
6.6
154
985
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
8.7
6.6
13
15
SPAT1153
SPAT
Removal of sutures
1.4
6.6
337
2571
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.9
6.5
38
135
E000003
ATC
NA
2.3
6.5
58
261
S01AX11
ATC
[U] ofloxacin; ophthalmic
2.6
6.5
43
166
S09
ICPC
Infected finger/toe
2.9
6.5
38
136
R03BB04
ATC
tiotropium bromide; inhalant
1.9
6.5
93
511
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
6.2
6.5
16
26
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.1
6.5
33
109
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.1
6.5
72
359
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.9
6.4
37
130
M05.2
ICD-10 Finland
Rheumatoid vasculitis
70.2
6.4
7
*
M01AX17
ATC
nimesulide; oral
1.5
6.4
264
1926
NG1EA
NOMESCO Finland
Knee X-ray examination with wrench
4.7
6.4
20
43
I50.1
ICD-10 Finland
Left ventricular failure
2.8
6.4
38
138
WX199
NOMESCO Finland
Other local analgesia
3.3
6.4
29
88
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.3
6.4
29
88
N06AX21
ATC
duloxetine; oral
1.7
6.4
130
799
M54.5
ICD-10 Finland
Low back pain
1.4
6.4
374
2919
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.4
6.3
28
83
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
6.6
6.3
15
23
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
6.6
6.3
15
23
M05BX03
ATC
strontium ranelate; oral
8.2
6.3
13
16
XFE00
NOMESCO Finland
Epicardial ultrasonography
3.1
6.3
32
105
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
6.3
139
872
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
6.0
6.3
16
27
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
11.1
6.3
11
10
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
6.3
265
1943
H15.1
ICD-10 Finland
Episcleritis
3.9
6.3
24
63
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.2
6.3
31
100
C09CA01
ATC
losartan; oral
1.5
6.3
232
1653
R00.2
ICD-10 Finland
Palpitations
1.9
6.3
91
501
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.9
6.3
89
486
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
3.4
6.3
28
84
N03AX14
ATC
levetiracetam; systemic
3.1
6.3
32
106
M33.1
ICD-10 Finland
Other dermatomyositis
+∞
6.3
6
*
4209X
ICD-9 Finland
Acute pericarditis, Other and unspecified acute pericarditis[PERICARDITIS ALIA DEFINITA SEU NUD]
+∞
6.3
6
*
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
+∞
6.3
6
*
N085, M318
ICD-10 Finland
NA
+∞
6.3
6
*
M31.2
ICD-10 Finland
Lethal midline granuloma
+∞
6.3
6
*
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
4.3
6.2
21
49
I25.2
ICD-10 Finland
Old myocardial infarction
2.4
6.2
48
203
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.2
586
4951
SPAT1216
SPAT
Assessment of functional ability
1.6
6.2
144
918
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
2.5
6.2
47
196
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
5.8
6.2
16
28
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
6.1
110
652
J01MA01
ATC
ofloxacin; systemic
1.9
6.1
88
483
N89.0
ICD-10 Finland
Mild vaginal dysplasia
7.7
6.1
13
17
J12.9
ICD-10 Finland
Viral pneumonia, unspecified
7.7
6.1
13
17
GD1UN
NOMESCO Finland
Lung circulation SPECT
7.7
6.1
13
17
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
3.5
6.1
26
75
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
3.0
6.1
32
108
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.7
6.1
24
65
F45.8
ICD-10 Finland
Other somatoform disorders
1.9
6.1
88
487
N87.1
ICD-10 Finland
Moderate cervical dysplasia
2.9
6.1
35
124
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.6
6.1
40
155
L56.4
ICD-10 Finland
Polymorphous light eruption
8.6
6.1
12
14
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.4
6.1
27
81
R04.0
ICD-10 Finland
Epistaxis
2.0
6.1
69
347
H03AA01
ATC
levothyroxine sodium; systemic
1.4
6.1
296
2232
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.8
6.0
91
509
ZXC12
NOMESCO Finland
Pulse colorlaser
10.1
6.0
11
11
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
6.1
6.0
15
25

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: M13_SLE – Systemic lupus erythematosus

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).