relapsing polychondritis: Relapsing polychondritis (RP) is a rare, clinically heterogeneous, multisystemic inflammatory disease characterized by inflammation of the cartilage and proteoglycan rich structures leading to cartilage damage with joint, ocular and cardiovascular involvement.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
81 |
4. Check minimum number of eventsNone |
81 |
5. Include endpointsNone |
81 |
6. Filter based on genotype QC (FinnGen only) |
81 |
Control definitions (FinnGen only)
- Control exclude
- M13_OTHERBONE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M94
- Name in latin
- Polychondritis recidiva
Similar endpoints
↥List of similar endpoints to
Relapsing polychondritis
based on the number of shared cases.
Similar with more cases:
- Chondropathies
- Other disorders of bone
- Osteopathies and chondropathies
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 349 | 227 | 121 |
| Only index persons | 333 | 217 | 116 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 52.03 | 50.64 | 54.42 |
| Only index persons | 51.38 | 50.03 | 53.90 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 81 | 56 | 25 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 51.72 | 49.92 | 55.76 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 67
- Matched controls
- 670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M94.1
ICD-10 Finland
Relapsing polychondritis
+∞
96.2
67
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
30.1
28.6
41
33
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
16.2
19.7
35
42
H02AB06
ATC
prednisolone; systemic
7.6
12.3
53
222
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
15.7
9.4
15
12
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.6
8.0
36
134
L04AX01
ATC
azathioprine; systemic
11.2
7.2
13
14
A46
ICD-10 Finland
Erysipelas
6.8
7.1
18
34
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.1
6.6
32
122
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
76.9
6.5
7
*
P01BA02
ATC
hydroxychloroquine; oral
6.1
6.3
17
35
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.8
6.2
38
173
J01FA06
ATC
roxithromycin; oral
3.7
6.1
40
193
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3037522) Nuclear Ab [Titer] in Serum
41
103
7.04
17.39
1.9
1.3
titre
360.0
469.2
0.39
15
26
(3022096) Basophils/100 leukocytes in Blood
64
297
6.50
12.49
14.5
5.6
%
0.8
0.7
0.30
64
272
(3005719) IgG [Mass/volume] in Serum or Plasma
25
52
6.51
12.41
2.3
1.9
g/l
11.8
9.9
0.95
25
46
(3006504) Eosinophils/100 leukocytes in Blood
64
303
6.30
12.02
14.7
5.7
%
2.9
2.7
0.20
64
280
(3019069) Monocytes/100 leukocytes in Blood
64
306
6.20
11.79
14.9
6.0
%
9.0
8.1
2.35
64
285
(3018010) Neutrophils/100 leukocytes in Blood
64
308
6.14
11.64
14.2
5.7
%
57.2
58.0
0.26
64
288
(3002030) Lymphocytes/100 leukocytes in Blood
64
313
5.98
11.27
14.8
5.8
%
28.3
27.8
0.14
64
290
(3028026) IgM [Mass/volume] in Serum or Plasma
20
42
6.00
9.67
1.7
1.7
g/l
1.2
1.0
0.35
20
37
(42870588) Differential panel, method unspecified - Blood
49
216
4.21
9.31
13.3
4.9
—
—
—
0
0
(40758558) Short blood count panel - Blood
43
176
4.08
9.01
11.8
6.9
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
14
23
7.15
8.49
1.7
1.6
—
—
—
0
0
(3015736) pH of Urine
53
263
3.94
8.15
3.4
3.3
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
16
33
5.80
7.79
1.2
1.2
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
11
16
7.80
7.35
1.5
1.3
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
58
336
3.56
6.44
5.1
3.5
estimate
0.0
0.0
0.00
11
71
(3013707) Erythrocyte sedimentation rate by Westergren method
73
517
5.16
6.37
9.8
3.9
mm/h
11.0
10.3
0.18
73
469
(3018095) Leukocytes [#/volume] in Urine
46
234
3.24
6.31
3.9
3.2
e6/l
45.2
48.7
0.04
32
168
(3021601) Nitrite [Presence] in Urine by Test strip
58
339
3.50
6.29
6.7
4.9
estimate
0.0
0.0
0.00
12
73
(3009261) Glucose [Presence] in Urine by Test strip
58
342
3.45
6.13
5.1
3.5
estimate
0.0
0.0
0.00
12
69
(3037467) Urinalysis macro (dipstick) panel - Urine
69
460
4.38
5.89
8.2
3.6
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
11
21
5.90
5.70
1.3
1.0
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
23
82
3.52
5.55
2.3
1.3
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
39
192
2.99
5.49
2.9
2.7
e6/l
72.9
27.4
0.35
31
155
(3025159) Blasts/100 leukocytes in Blood
18
55
3.92
5.41
3.4
4.3
%
0.0
0.0
—
5
14
(3021879) Hepatitis B virus core Ab [Presence] in Serum
16
45
4.18
5.36
1.4
1.6
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
37
180
2.94
5.28
7.4
5.4
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
32
144
3.02
5.24
1.6
1.3
iu/ml
10.4
41.2
—
10
45
(3021440) Promyelocytes/100 leukocytes in Blood
18
57
3.77
5.13
4.5
4.3
%
0.0
0.3
—
5
18
(3017181) Myelocytes/100 leukocytes in Blood
19
63
3.63
5.07
4.3
4.1
%
0.6
0.8
—
5
20
(3011397) Hemoglobin [Presence] in Urine by Test strip
31
140
2.97
5.02
3.9
3.6
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
9
10
9.95
4.92
1.2
1.2
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
9
10
9.95
4.92
1.2
1.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
9
10
9.95
4.92
1.2
1.2
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
9
10
9.95
4.92
1.2
1.2
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
9
10
9.95
4.92
1.2
1.2
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
9
10
9.95
4.92
1.2
1.2
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
31
142
2.92
4.87
1.7
1.4
g/l
1.8
2.4
2.21
24
92
(4062490)
7
5
15.12
4.66
1.1
1.0
—
—
—
0
0
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
7
6
12.60
4.36
1.3
1.3
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
48
290
2.61
4.25
5.5
5.5
mmol/l
1.2
1.2
0.31
42
240
(3030467) Casts [#/volume] in Urine by Automated count
34
177
2.59
4.06
2.8
2.5
e6/l
0.1
0.4
1.71
27
137
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
8
11
7.92
3.96
1.1
1.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
35
188
2.52
3.89
3.8
2.3
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
16
57
3.25
3.78
4.8
4.1
%
0.4
0.8
—
5
12
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
8
12
7.26
3.77
1.4
1.3
—
—
—
0
0
(3018418) pH of Serum or Plasma
34
183
2.48
3.73
3.6
3.4
ph
7.4
7.4
—
5
37
(3017143) Hepatitis C virus Ab [Presence] in Serum
20
83
2.87
3.66
1.2
1.5
—
—
—
0
0
(3008898) HLA-B27 [Presence]
11
31
3.95
3.62
1.3
1.1
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
37
219
2.27
3.18
3.3
2.8
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
19
83
2.68
3.14
1.6
1.5
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
27
141
2.37
3.08
1.3
1.3
u/ml
1.1
9.0
1.51
12
56
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
22
105
2.50
3.04
1.5
1.5
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
25
127
2.40
3.03
6.4
4.6
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
5
5
10.53
3.02
1.2
1.0
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
7
13
5.78
2.93
1.3
1.4
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
7
13
5.78
2.93
1.4
1.8
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
5
6
8.77
2.78
1.0
1.5
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
37
229
2.13
2.77
3.0
3.1
u/l
33.4
32.5
0.07
37
215
(3000850) Epithelial cells [#/volume] in Urine
26
142
2.22
2.64
2.5
2.1
e6/l
9.7
5.6
0.34
26
125
(3031040) Bacteria [#/volume] in Urine by Automated count
58
432
2.21
2.62
5.8
3.7
—
34.6
—
0
7
(40768797) Stomach Pathology biopsy report
19
91
2.42
2.58
1.1
1.3
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
28
159
2.16
2.58
1.3
1.3
u/ml
4.6
0.9
—
9
44
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
17
79
2.46
2.46
2.2
1.7
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
18
86
2.41
2.46
1.7
2.1
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
41
275
1.99
2.38
5.5
3.6
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
7
18
4.15
2.31
3.4
3.1
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
14
61
2.57
2.30
2.7
4.0
u/l
236.6
250.0
0.30
14
61
(3024561) Albumin [Mass/volume] in Serum or Plasma
41
278
1.96
2.29
3.8
3.5
g/l
35.8
36.2
0.19
41
261
(36304419) Bacteria [Presence] in Urine
29
174
2.04
2.28
2.8
2.4
—
—
—
0
0
(3000492) Spirometry study
13
55
2.62
2.26
2.2
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
5
9
5.83
2.24
1.2
1.7
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
5
9
5.83
2.24
1.2
1.7
—
—
—
0
0
(3000991) Gas panel - Venous blood
11
43
2.80
2.20
7.6
5.8
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
26
152
2.05
2.18
2.7
1.7
mg/l
0.5
1.3
1.73
21
123
(3026782) Osmolality of Urine
22
126
2.02
1.93
2.6
2.5
mosm/kgh2o
598.6
558.4
0.27
22
106
(3004119) Hemoglobin [Mass/volume] in Venous blood
8
28
3.06
1.92
2.8
2.8
g/l
128.1
133.2
—
8
28
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
9
35
2.76
1.87
6.9
4.4
mmol/l
23.9
24.5
—
9
35
(3029937) Albumin [Presence] in Urine by Test strip
30
194
1.87
1.85
6.5
3.7
estimate
0.0
0.0
0.00
12
71
(3012544) pH of Venous blood
11
48
2.49
1.79
3.3
2.4
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
8
30
2.84
1.78
1.8
2.5
%
1.0
1.5
—
8
30
(3019832) Treponema pallidum Ab [Presence] in Serum
14
71
2.17
1.66
1.4
1.7
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
69
590
2.14
1.65
32.6
14.6
%
14.0
13.6
1.54
69
578
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
7
26
2.85
1.62
1.1
1.4
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
18
102
1.98
1.61
2.7
2.3
e6/l
0.9
0.8
—
10
63
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
6
20
3.15
1.61
1.3
1.8
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
21
127
1.88
1.56
1.8
1.4
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
14
73
2.11
1.55
2.6
1.8
%
21.3
24.9
0.54
14
62
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
16
88
2.02
1.55
2.6
2.6
e6/l
0.8
3.5
—
8
50
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
19
112
1.91
1.52
4.5
3.2
ng/l
182.0
167.8
—
8
79
(3001122) Ferritin [Mass/volume] in Serum or Plasma
39
286
1.70
1.52
3.6
2.6
ug/l
124.2
103.1
0.33
39
266
(3041096) Erythrocytes [Presence] in Urine by Automated
30
205
1.74
1.50
5.5
3.1
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
21
129
1.85
1.49
2.0
1.8
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
7
28
2.64
1.49
1.9
1.4
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
9
39
2.47
1.48
1.4
1.6
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
6
22
2.86
1.46
1.3
2.0
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
29
198
1.72
1.45
2.1
2.2
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
34
245
1.67
1.39
19.0
5.6
inr
1.3
1.1
0.67
15
75
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
40
301
1.65
1.38
3.1
3.9
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
39
292
1.65
1.37
2.6
1.9
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
49
392
1.63
1.30
4.1
4.0
mmol/l
6.2
6.6
1.11
49
366
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
25
2.51
1.27
9.8
8.0
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
19
2.73
1.23
1.6
1.4
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
10
50
2.14
1.22
2.7
1.6
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
8
39
2.16
1.19
1.8
1.3
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
21
138
1.70
1.18
1.9
2.2
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
5
21
2.47
1.10
1.0
2.0
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
10
53
2.01
1.06
1.2
1.2
iu/ml
48.8
149.6
—
5
19
(3022948) Iron [Moles/volume] in Serum or Plasma
15
92
1.77
1.06
3.6
1.8
umol/l
11.8
14.3
0.86
15
81
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
22
2.35
1.05
1.4
1.1
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
31
232
1.54
1.04
2.0
1.8
pmol/l
90.9
96.8
0.29
19
123
(40768443) Skin Pathology biopsy report
7
35
2.09
1.03
1.1
1.1
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
13
77
1.82
1.02
3.5
2.1
nmol/l
286.3
361.6
0.70
13
70
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
10
54
1.97
1.02
2.7
1.6
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
32
244
1.51
0.97
4.4
3.7
ng/l
17.6
46.2
1.02
21
158
(40761535) Cells panel - Urine sediment
10
55
1.93
0.97
3.3
3.3
—
—
—
0
0
(3003338) MCHC [Mass/volume]
67
604
1.63
0.86
30.1
15.3
g/l
331.8
332.1
0.12
67
604
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
6
34
1.82
0.78
2.8
1.9
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
5
26
1.98
0.72
3.6
3.4
mmol/l
24.7
24.8
—
5
26
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
5
26
1.98
0.72
2.6
1.5
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
22
281
0.70
0.67
2.3
2.8
—
—
—
0
0
(3044889) 12 lead EKG panel
54
482
1.36
0.59
4.4
3.5
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
23
0.00
0.59
0.0
2.3
—
2.3
—
0
17
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
10
66
1.59
0.55
3.4
3.6
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
52
467
1.32
0.51
3.6
3.2
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
7
45
1.61
0.50
1.6
2.2
e9/l
3.8
3.8
—
7
37
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
10
136
0.70
0.42
1.8
1.7
pmol/l
483.1
476.0
—
10
117
(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose
0
15
0.00
0.41
0.0
1.2
—
8.2
—
0
9
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
16
0.00
0.41
0.0
1.7
—
25.0
—
0
16
(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting
0
16
0.00
0.41
0.0
1.1
—
1.1
—
0
16
(21494755) Public health laboratory ask at order entry panel
10
72
1.44
0.39
1.0
1.3
—
—
—
0
0
(1002224) Polysomnography panel
5
36
1.41
0.39
1.0
1.0
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
11
81
1.41
0.38
2.3
2.1
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
76
730
1.66
0.37
18.2
11.1
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
6
41
1.50
0.37
1.7
1.2
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
43
1.43
0.36
1.0
1.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
67
635
1.32
0.35
25.8
12.5
%
39.7
39.9
0.06
55
481
(3020682) Albumin/Creatinine [Ratio] in Urine
16
194
0.78
0.32
3.4
3.8
mg/mmol
3.2
8.4
—
10
118
(3012516) Albumin [Mass/volume] in Urine
15
183
0.78
0.32
2.5
3.1
mg/l
14.8
55.3
—
9
118
(36660697) Celiac disease serology panel - Serum
7
56
1.27
0.30
1.1
1.1
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
9
75
1.22
0.26
3.3
2.7
umol/l
6.9
7.9
—
9
64
(40768795) Lymph node Pathology biopsy report
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3008295) Osmolality of Serum or Plasma
0
10
0.00
0.21
0.0
1.2
—
271.8
—
0
5
(3022806) Fractional oxyhemoglobin in Capillary blood
0
10
0.00
0.21
0.0
1.8
—
91.8
—
0
10
(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay
0
12
0.00
0.21
0.0
1.1
—
0.8
—
0
5
(3001019) Free T4 and TSH panel - Serum or Plasma
6
49
1.24
0.20
1.2
1.9
—
—
—
0
0
(3003181) Sodium [Moles/volume] in Urine
0
14
0.00
0.20
0.0
1.4
—
50.6
—
0
14
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
11
92
1.23
0.17
2.5
2.1
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
9
77
1.19
0.16
3.3
3.0
mmol/l
1.0
1.0
—
9
72
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
9
78
1.17
0.16
3.9
6.1
—
—
—
0
0
(3022145) Colonoscopy Study observation
9
81
1.12
0.15
1.1
1.3
—
—
—
0
0
(3002256) Pathology report gross observation
10
85
1.20
0.13
2.4
1.2
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
17
186
0.89
0.10
1.2
1.5
—
—
—
0
0
(4010399)
6
54
1.12
0.09
2.5
1.4
—
—
—
0
0
(3019225) pH of Specimen
6
55
1.10
0.09
1.3
3.8
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
5
62
0.79
0.08
1.0
1.8
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
9
87
1.04
0.07
1.4
1.7
%
1.3
1.4
—
9
75
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
54
532
1.05
0.02
5.9
4.3
pmol/l
14.6
14.7
0.01
54
496
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
17
177
0.95
0.01
6.4
5.1
ug/l
1.9
1.8
0.06
17
161
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
69
684
1.06
0.01
3.7
4.5
mmol/l
1.5
1.5
0.18
69
630
(3013512) EKG study
19
188
1.01
0.00
5.3
3.6
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
14
144
0.97
0.00
1.3
1.4
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
14
141
0.99
0.00
5.1
4.5
%
24.5
20.8
—
6
64
(40761536) Microorganisms panel - Urine sediment
6
65
0.92
0.00
14.0
2.8
—
—
—
0
0
(4281824)
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
6
63
0.95
0.00
2.0
1.6
—
—
—
0
0
(3006571) Polymorphonuclear cells/100 leukocytes in Synovial fluid
0
5
0.00
0.00
0.0
1.6
—
56.8
—
0
5
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
6
60
1.00
0.00
2.0
1.3
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
14.4
—
877.6
—
0
7
(3013637) Mi-2 Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
4.8
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(42529582) MDA5 Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
9
0.00
0.00
0.0
5.7
—
127.2
—
0
9
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
17.3
—
1439.1
—
0
7
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.0
—
22.2
—
0
9
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026470) Cobalt [Mass/volume] in Blood
0
6
0.00
0.00
0.0
2.7
—
5.5
—
0
6
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
4.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_RELAPSPOLYCHONDR and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have M13_RELAPSPOLYCHONDR.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: M13_RELAPSPOLYCHONDR – Relapsing polychondritis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data