Hypersensitivity angiitis

M13_HYPERANG

hypersensitivity vasculitis: Disorder characterized by a vasculitic syndrome associated with exposure to an antigen such as a drug, infectious agent, or other foreign or endogenous substance. Its pathophysiology includes immune complex deposition and a wide range of skin lesions. Hypersensitivity or allergy is present in some but not all cases.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M31.0
  • Hospital discharge: ICD-9 4462A
  • Hospital discharge: ICD-8 4461
  • Cause of death: ICD-10 M31.0
  • Cause of death: ICD-9 4462A
  • Cause of death: ICD-8 4461

2 out of 7 registries used, show all original rules.

179

4. Check minimum number of events

None

179

5. Include endpoints

None

179

6. Filter based on genotype QC (FinnGen only)

179

Control definitions (FinnGen only)

Control exclude
M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M31
Name in latin
Angi(i)tis hypersensitivitatis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1066 579 476
Only index persons 811 452 359
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.02 0.01
Median age at first event (years)
Whole population 60.49 61.23 59.53
Only index persons 57.92 58.46 57.23

-FinnGen-

Key figures

All Female Male
Number of individuals 179 94 85
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 58.05 56.90 59.32

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
164
Matched controls
1638
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
111.6
94
*
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
65.0
58
*
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
60.2
54
*
L04AX01
ATC
azathioprine; systemic
61.2
54.1
62
16
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
19.8
52.3
87
88
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
48.3
44
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
59.1
43.4
50
12
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
67.1
42.6
48
10
L04AA06
ATC
mycophenolic acid; systemic
96.1
40.2
43
6
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
36.9
34
*
H02AB04
ATC
methylprednisolone; systemic
10.3
31.8
71
113
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
17.5
31.4
51
41
A11CC03
ATC
alfacalcidol; systemic
32.6
30.6
40
16
4462A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Hypersensitivity angiitis
+∞
30.1
28
*
Z94.0
ICD-10 Finland
Kidney transplant status
98.2
30.0
32
*
TK800
NOMESCO Finland
Hemodialysis
30.3
27.1
36
15
A12AA04
ATC
calcium carbonate; oral
43.7
26.4
32
9
127
Kela drug reimbursment
Transplant complication
69.8
26.0
29
5
Z49.1
ICD-10 Finland
Extracorporeal dialysis
47.2
26.0
31
8
WW400
NOMESCO Finland
Plasmaferesis
292.6
25.4
25
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
66.9
24.9
28
5
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
139.5
23.2
24
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.5
23.2
97
339
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
45.7
22.5
27
7
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
11.4
22.5
44
51
L01AA01
ATC
cyclophosphamide; systemic
+∞
22.4
21
*
B03XA02
ATC
darbepoetin alfa; parenteral
40.0
21.9
27
8
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
15.6
20.5
34
27
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
10.9
19.3
38
44
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
41.9
18.1
22
6
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
+∞
17.0
16
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
100.4
16.9
18
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
12.8
16.8
30
28
N18.0
ICD-10 Finland
End-stage renal disease
45.1
16.8
20
5
ZXD05
NOMESCO Finland
Urgent procedure
4.2
16.3
84
327
KA1AE
NOMESCO Finland
Kidney ultrasound examination
19.8
16.2
24
14
N18.8
ICD-10 Finland
Other chronic renal failure
16.0
16.2
26
19
M05BA04
ATC
alendronic acid; oral
7.1
16.1
42
76
TPX10
NOMESCO Finland
Implantation of vascular injection port
17.1
16.0
25
17
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.0
16.0
101
469
C03CA01
ATC
furosemide; systemic
4.1
15.9
85
340
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
15.9
15
*
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
15.9
15
*
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
15.9
15
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
94.3
15.9
17
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.4
15.0
50
123
H02AB06
ATC
prednisolone; systemic
3.8
14.7
103
506
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
11.0
14.7
28
30
TPH04
NOMESCO Finland
Cathetrisation of vein
4.5
14.6
61
191
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
10.1
14.5
29
34
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.9
14.1
51
137
H02AB07
ATC
prednisone; oral
5.5
13.8
44
102
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
13.7
13
*
L04AD01
ATC
ciclosporin; systemic
28.6
13.7
18
7
WW200
NOMESCO Finland
Immunization
17.0
13.5
21
14
B03XA01
ATC
erythropoietin; parenteral
31.3
13.2
17
6
ZX120
NOMESCO Finland
Intravenous
6.0
13.1
38
78
A07AA02
ATC
nystatin; oral
7.2
13.0
32
53
137
Kela drug reimbursment
Uraemia requiring dialysis
75.9
12.8
14
*
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
75.9
12.8
14
*
Z2446
NOMESCO Finland
Social worker
7.4
12.8
31
50
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
12.7
12
*
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
12.7
12
*
WX892
NOMESCO Finland
Monitored bed care
6.8
12.5
32
56
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
40.9
12.4
15
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
23.5
12.3
17
8
R4110
NOMESCO Finland
Physiotherapy
3.7
12.1
66
254
ZX108
NOMESCO Finland
Inhalation
50.7
12.1
14
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
12.5
11.9
21
19
V03AE01
ATC
polystyrene sulfonate; oral
32.7
11.9
15
5
R50.9
ICD-10 Finland
Fever, unspecified
5.1
11.9
40
98
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
10.9
11.7
22
23
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.2
11.1
36
84
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.7
11.1
40
105
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
4.0
11.1
50
163
Z3231
NOMESCO Finland
Registered nurse
3.4
10.9
66
270
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
11.2
10.9
20
20
J01MA02
ATC
ciprofloxacin; systemic
3.1
10.8
87
437
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
6.8
10.7
27
46
Z3226
NOMESCO Finland
Physiotherapist
3.8
10.6
51
175
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
6.4
10.6
28
51
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
10.5
10
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
8.9
10.5
22
28
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
11.1
10.3
19
19
L04AA01
ATC
[U] ciclosporin; systemic
28.0
10.0
13
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.2
9.9
64
272
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
105.8
9.5
10
*
N08.5*M30.0
ICD-10 Finland
Glomerular disorders in polyarteritis nodosa
+∞
9.5
9
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
+∞
9.5
9
*
J01MA14
ATC
moxifloxacin; systemic
5.3
9.4
29
64
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
25.7
9.0
12
5
TKC20
NOMESCO Finland
Catheterisation of bladder
5.8
8.9
25
49
R31
ICD-10 Finland
Unspecified haematuria
4.8
8.9
30
73
XF400
NOMESCO Finland
ECG with 12 standard connections
3.6
8.9
44
153
B05DA
ATC
Isotonic solutions
94.7
8.5
9
*
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
+∞
8.4
8
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
8.4
8
*
N19
ICD-10 Finland
Unspecified kidney failure
7.5
8.3
19
28
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
6.5
8.3
21
36
J01FF01
ATC
clindamycin; systemic
2.9
8.2
61
276
TK810
NOMESCO Finland
Hemofiltration
35.2
8.2
10
*
Z2221
NOMESCO Finland
Medical doctor
2.9
8.1
56
245
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.7
8.0
27
66
205
Kela drug reimbursment
Chronic hypertension
2.7
7.9
68
339
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.4
7.8
28
73
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
4.6
7.6
26
64
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
4.1
7.6
30
85
ZXE20
NOMESCO Finland
More than three and less than five hours
3.4
7.6
38
132
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
7.6
58
267
A02BC02
ATC
pantoprazole; systemic
2.6
7.6
115
775
B01AB10
ATC
tinzaparin; parenteral
5.2
7.6
23
50
GD1AD
NOMESCO Finland
Thorax CT examination
6.8
7.5
18
29
321
Kela drug reimbursment
Paricalcitol and cinacalcet
83.7
7.5
8
*
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
83.7
7.5
8
*
Z49.2
ICD-10 Finland
Other dialysis
83.7
7.5
8
*
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
83.7
7.5
8
*
D69.0
ICD-10 Finland
Allergic purpura
83.7
7.5
8
*
WX203
NOMESCO Finland
Infraclavicular plexus blockade
11.6
7.4
13
12
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
+∞
7.3
7
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
7.3
7
*
N085, M318
ICD-10 Finland
NA
+∞
7.3
7
*
N25.0
ICD-10 Finland
Renal osteodystrophy
+∞
7.3
7
*
C08CA02
ATC
felodipine; oral
3.8
7.3
31
94
ZXA00
NOMESCO Finland
Right side
2.7
7.2
61
298
Z49.0
ICD-10 Finland
Preparatory care for dialysis
21.1
7.2
10
5
R4190
NOMESCO Finland
Nutritional therapy
9.4
7.2
14
16
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
9.4
7.2
14
16
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
6.0
7.2
19
35
J01MA12
ATC
levofloxacin; systemic
3.0
7.2
44
177
P01BA02
ATC
hydroxychloroquine; oral
5.0
7.1
22
49
TGC00
NOMESCO Finland
Bronchial lavation
8.1
7.1
15
20
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
11.6
6.9
12
11
N17.8
ICD-10 Finland
Other acute renal failure
17.6
6.8
10
6
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
41.8
6.8
8
*
WX002
NOMESCO Finland
Sedation and analgesia
2.9
6.7
46
196
A41.9
ICD-10 Finland
Sepsis, unspecified
7.4
6.7
15
22
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
10.7
6.6
12
12
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.1
6.6
37
139
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.3
6.5
35
126
ZXE40
NOMESCO Finland
More than seven and less than nine hours
15.1
6.5
10
7
XQ845
NOMESCO Finland
Dermatoscopy
15.1
6.5
10
7
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
72.5
6.5
7
*
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
72.5
6.5
7
*
A02BC01
ATC
omeprazole; systemic
2.5
6.4
58
290
N02AX02
ATC
tramadol; systemic, rectal
2.4
6.4
79
462
TPH07
NOMESCO Finland
Cathetrisation of artery
3.4
6.4
31
105
L57.0
ICD-10 Finland
Actinic keratosis
3.7
6.4
27
82
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
6.8
6.3
15
24
C08CA01
ATC
amlodipine; oral
2.4
6.3
71
396
V03AE02
ATC
sevelamer; oral
27.8
6.3
8
*
N085M
ICD-10 Finland
NA
+∞
6.3
6
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
6.3
6
*
PAW37
NOMESCO Finland
Biopsy of temporal artery
+∞
6.3
6
*
1CX01
NOMESCO Finland
NA
+∞
6.3
6
*
B05DB
ATC
Hypertonic solutions
+∞
6.3
6
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
+∞
6.3
6
*
4476A
ICD-9 Finland
Other disorders of arteries and arterioles, Arteritis, unspecified
+∞
6.3
6
*
6BA02
NOMESCO Finland
NA
+∞
6.3
6
*
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
5.3
6.3
18
37
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
6.3
57
284
UKC02
NOMESCO Finland
Cystoscopy
3.1
6.1
34
126
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
6.1
69
387
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
4.1
6.1
23
63
TQW99
NOMESCO Finland
Other minor procedure on skin
5.8
6.0
16
30

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
51
34
20.58
60.42
5.8
1.1
iu/ml
16.2
—
—
11
0
(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
51
44
15.81
52.21
4.2
1.4
titre
91.4
—
—
7
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
89
179
8.90
47.95
25.9
6.5
mmol/l
1.2
1.0
3.30
84
167
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
39
24
20.50
47.54
2.8
1.1
titre
400.0
—
—
10
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
37
8
57.80
32.05
8.6
1.1
u/ml
42.6
—
—
5
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
27
20
15.72
29.45
2.4
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
36
48
9.14
26.50
3.4
2.0
u/ml
0.2
0.3
0.73
20
28
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
26
22
13.66
26.20
1.4
1.2
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
70
194
5.28
24.92
8.7
2.6
%
21.9
21.1
0.24
61
169
(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
25
22
13.05
24.55
1.6
1.2
u/ml
344.1
275.2
0.20
17
14
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
23
18
14.51
24.18
6.5
1.1
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
110
445
4.82
24.10
14.1
4.9
—
—
—
0
0
(3000991) Gas panel - Venous blood
52
114
6.02
24.03
19.8
8.2
—
—
—
0
0
(3012095) Magnesium [Moles/volume] in Serum or Plasma
75
228
4.94
23.71
5.4
3.6
mmol/l
0.8
0.8
0.01
69
214
(3002032) Base excess in Venous blood by calculation
55
136
5.39
22.10
16.9
4.0
mmol/l
1.3
2.1
0.82
49
103
(3012544) pH of Venous blood
54
137
5.21
20.98
17.0
4.2
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
58
158
4.95
20.67
2.0
1.6
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
18
12
16.57
20.49
1.2
1.1
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
70
225
4.47
20.16
2.5
1.7
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
18
13
15.28
19.63
2.3
2.1
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
57
163
4.66
18.97
2.1
1.7
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
44
104
5.28
18.38
1.7
3.0
g/l
60.5
66.8
6.16
39
91
(3048929) Epstein Barr virus Ab [Presence] in Serum
27
39
7.98
18.36
1.4
1.3
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
94
395
3.91
18.25
8.0
4.3
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
21
22
10.68
18.25
5.6
4.0
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
128
678
4.12
17.27
16.6
5.0
e9/l
0.6
0.6
1.08
123
583
(3006315) Basophils [#/volume] in Blood
128
680
4.10
17.15
16.7
5.1
e9/l
0.0
0.0
0.07
123
587
(3013115) Eosinophils [#/volume] in Blood
131
708
4.17
17.08
17.7
5.3
e9/l
0.2
0.2
0.39
124
622
(3019198) Lymphocytes [#/volume] in Blood
129
697
4.05
16.66
16.6
5.2
e9/l
1.8
1.9
0.19
124
616
(3042733) HLA Ab [Presence] in Serum
15
0
+∞
15.86
4.7
0.0
—
—
—
0
0
(3000504) BK virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
15
0
+∞
15.86
5.1
0.0
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
108
532
3.60
15.82
13.8
3.1
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
78
316
3.60
15.50
8.2
2.6
e6/l
3.2
4.5
0.86
78
280
(3019230) Fractional oxyhemoglobin in Venous blood
18
19
10.42
15.48
5.2
2.1
%
80.3
67.6
1.40
18
19
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
27
47
6.59
15.44
2.6
1.2
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
50
150
4.24
15.36
3.7
1.5
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
93
427
3.45
15.05
8.8
3.0
mmol/l
6.1
7.8
4.74
88
362
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
48
142
4.25
14.99
4.4
3.7
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
24
38
7.14
14.97
1.7
1.6
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
16
16
10.88
14.23
1.1
1.1
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
36
89
4.81
14.07
1.6
2.7
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
15
14
11.60
13.94
1.1
1.0
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
38
99
4.60
13.92
2.4
1.2
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
19
25
8.38
13.83
1.5
1.6
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
91
431
3.26
13.68
10.6
3.9
mg/mmol
43.5
7.9
1.33
76
265
(3012516) Albumin [Mass/volume] in Urine
87
403
3.25
13.55
9.1
3.1
mg/l
165.3
211.1
0.11
74
264
(3018095) Leukocytes [#/volume] in Urine
101
516
3.20
13.21
14.3
3.6
e6/l
74.3
93.2
0.13
93
382
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
54
190
3.64
13.03
3.7
1.6
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
49
162
3.79
12.96
2.1
1.3
titre
1196.9
330.3
0.81
13
35
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
22
37
6.64
12.93
1.5
1.5
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
32
78
4.78
12.67
7.6
5.8
mmol/l
24.3
25.1
0.54
32
78
(3018418) pH of Serum or Plasma
89
433
3.10
12.51
21.5
4.0
ph
7.4
7.4
0.16
17
81
(3013650) Neutrophils [#/volume] in Blood by Automated count
132
811
3.39
12.17
20.3
8.8
e9/l
4.4
4.2
0.59
125
709
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
13
12
11.60
12.10
1.3
1.3
—
—
—
0
0
(3011648) Oxygen content in Venous blood
12
10
12.79
11.86
3.9
2.2
%
11.8
11.5
—
12
10
(21494890) Protein electrophoresis panel - 24 hour Urine
12
10
12.79
11.86
1.1
4.6
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
18
27
7.30
11.70
1.6
1.2
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
61
247
3.23
11.63
10.2
2.8
e6/l
0.5
1.0
1.90
45
148
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
37
108
4.06
11.59
1.8
1.4
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
120
711
3.09
11.52
34.7
7.6
mmol/l
1.2
1.2
0.02
106
594
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
14
16
9.41
11.27
1.7
1.4
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
117
689
3.02
11.26
9.3
3.7
estimate
0.0
0.0
0.00
20
117
(36304419) Bacteria [Presence] in Urine
81
392
2.95
11.23
11.1
3.1
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
12
11
11.62
11.18
4.2
4.4
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
115
677
2.95
10.96
9.3
3.7
estimate
0.0
0.0
0.00
20
127
(3032080) INR in Blood by Coagulation assay
104
582
2.88
10.88
8.7
9.1
inr
1.1
1.2
0.84
18
172
(3021601) Nitrite [Presence] in Urine by Test strip
115
679
2.94
10.87
13.8
5.0
estimate
0.0
0.0
0.00
21
119
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
19
34
6.13
10.47
5.9
1.2
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
57
235
3.09
10.41
10.8
2.9
e6/l
1.6
2.2
0.29
42
138
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
70
324
2.91
10.39
4.1
2.4
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
16
24
7.22
10.36
1.6
1.5
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
32
92
4.02
10.17
8.3
3.9
g/l
114.7
125.9
2.20
32
92
(3044640) Blood type and Crossmatch panel - Blood
86
448
2.77
10.14
4.6
2.7
—
—
—
0
0
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
14
7
21.54
9.97
3.6
2.0
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
67
313
2.82
9.66
7.7
3.5
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
15
23
7.03
9.51
5.7
3.2
—
—
—
0
0
(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum
17
30
6.16
9.47
1.4
1.1
u/ml
2.0
2.5
—
5
5
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
17
31
5.95
9.16
1.5
1.6
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
11
12
9.70
9.07
2.0
1.3
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
23
57
4.48
8.83
1.6
1.6
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
55
242
2.84
8.77
3.8
1.8
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
16
29
5.96
8.66
1.7
1.4
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
16
29
5.96
8.66
1.7
1.4
—
—
—
0
0
(44790047)
13
19
7.30
8.56
1.5
1.6
—
—
—
0
0
(44790048)
13
19
7.30
8.56
1.5
1.6
—
—
—
0
0
(44790049)
13
19
7.30
8.56
1.5
1.6
—
—
—
0
0
(44806118)
13
19
7.30
8.56
1.5
1.6
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
15
26
6.21
8.48
1.4
1.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
49
208
2.87
8.31
3.0
2.2
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
36
128
3.27
8.29
3.4
2.9
e9/l
88.5
70.6
1.24
23
100
(3037467) Urinalysis macro (dipstick) panel - Urine
137
958
2.83
8.26
14.9
4.2
—
—
—
0
0
(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay
11
5
23.29
8.12
1.0
1.0
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
11
14
8.31
8.08
1.3
1.1
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
11
6
19.41
7.70
1.3
1.2
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
15
29
5.55
7.59
1.6
4.1
—
—
—
0
0
(1616796) Gas panel - Central venous blood
14
26
5.76
7.37
4.9
3.2
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
43
181
2.81
7.33
2.4
1.7
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
10
13
8.09
7.19
1.2
1.8
—
—
—
0
0
(3037121) Protein [Mass/volume] in Urine
19
48
4.31
7.09
4.8
3.4
g/l
0.9
0.2
1.23
14
18
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
16
35
4.92
7.08
1.8
1.3
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
31
111
3.17
7.01
7.5
3.4
%
0.2
0.1
0.07
12
35
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
24
73
3.64
6.98
9.8
15.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
77
439
2.32
6.88
5.1
3.3
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
10
14
7.51
6.77
1.2
1.7
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
19
50
4.13
6.73
1.7
2.8
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
13
25
5.53
6.59
1.2
1.6
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
23
71
3.57
6.54
2.7
1.4
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
18
47
4.15
6.44
6.1
3.0
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
29
106
3.07
6.32
6.8
3.1
%
0.6
0.5
—
7
26
(3019309) Folate [Moles/volume] in Red Blood Cells
53
267
2.40
6.18
1.8
1.7
nmol/l
1141.1
1179.4
0.11
47
205
(40758558) Short blood count panel - Blood
63
346
2.27
6.00
16.7
6.4
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
91
580
2.16
5.97
7.9
2.6
ug/l
181.4
127.9
1.83
86
525
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
98
643
2.16
5.97
5.6
4.7
—
—
—
0
0
(4062490)
10
9
11.68
5.87
1.1
1.3
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
16
41
4.19
5.85
1.4
1.2
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
31
123
2.84
5.84
7.6
3.3
%
0.4
1.0
0.85
12
42
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
64
359
2.22
5.76
2.6
2.0
mg/l
2.8
3.2
1.16
55
311
(3022313) Gas panel - Capillary blood
20
62
3.51
5.64
7.1
2.8
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
119
855
2.17
5.58
10.8
5.0
mmol/l
6.6
6.7
0.35
113
789
(3025159) Blasts/100 leukocytes in Blood
28
108
2.89
5.54
7.4
3.4
%
0.1
0.3
—
8
31
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
51
265
2.29
5.48
4.2
3.8
ng/l
657.6
132.3
0.97
42
215
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
13
30
4.59
5.39
1.2
1.6
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
10
18
5.83
5.38
5.1
2.4
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
29
117
2.76
5.28
4.8
3.2
ml/min/173m2
40.4
61.6
—
8
49
(3003396) Base excess in Arterial blood by calculation
38
176
2.47
5.26
9.1
9.9
mmol/l
-0.7
1.5
1.81
30
143
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
8
6
13.87
5.13
1.5
1.2
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
136
1050
2.23
5.03
10.6
3.7
mm/h
19.1
12.6
3.36
128
952
(40761535) Cells panel - Urine sediment
28
116
2.68
4.84
11.1
3.4
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
10
20
5.24
4.84
5.0
2.5
e9/l
3.9
4.6
—
10
20
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
14
38
3.91
4.75
1.6
1.4
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
15
43
3.72
4.72
1.7
1.6
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
10
21
4.98
4.59
5.0
2.6
%
56.8
57.6
—
10
21
(3015377) Calcium [Moles/volume] in Serum or Plasma
75
488
1.92
4.28
5.6
3.4
mmol/l
2.3
2.4
2.37
67
423
(3021589) Normoblasts [#/volume] in Blood
91
631
1.90
4.28
25.3
9.9
e9/l
0.0
0.0
0.58
82
514
(3027273) Bicarbonate [Moles/volume] in Venous blood
21
81
2.80
4.15
14.7
3.9
mmol/l
24.6
25.0
0.19
21
81
(3024891) Influenza virus A+B Ag [Presence] in Specimen
13
37
3.71
4.13
1.5
1.2
—
—
—
0
0
(3045788) Cell count panel - Pleural fluid
8
10
8.31
4.10
1.5
1.1
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
51
295
2.02
4.06
1.8
1.4
g/l
1.9
2.7
1.85
30
177
(3051651) Icteric interference index of Serum or Plasma
9
14
6.70
4.03
5.6
2.1
—
—
—
0
0
(40768443) Skin Pathology biopsy report
16
54
3.16
3.96
1.8
1.3
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
8
12
6.92
3.71
1.4
1.4
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
8
12
6.92
3.71
1.5
1.4
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
18
69
2.79
3.60
2.9
2.5
—
—
—
0
0
(3039162) Centromere protein B Ab [Units/volume] in Serum
9
17
5.51
3.56
1.3
1.2
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
9
17
5.51
3.56
4.2
3.6
—
—
—
0
0
(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood
8
13
6.38
3.54
1.8
1.9
e6/l
342.7
704.7
—
8
6
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
10
27
3.86
3.40
1.4
1.3
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
10
27
3.86
3.40
1.6
1.8
—
—
—
0
0
(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
9
19
4.93
3.28
1.3
1.2
u/ml
—
1.4
—
0
5
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
8
15
5.53
3.23
1.6
1.7
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
8
15
5.53
3.23
1.6
1.7
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
8
15
5.53
3.23
1.6
1.7
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
8
15
5.53
3.23
1.0
1.1
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
7
11
6.57
3.21
3.0
2.5
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
25
121
2.24
3.11
9.3
4.1
mmol/l
1.2
1.2
0.77
25
104
(3013290) Carbon dioxide [Partial pressure] in Blood
10
29
3.59
3.09
5.8
2.9
kpa
5.0
5.0
—
10
29
(3027315) Oxygen [Partial pressure] in Blood
10
29
3.59
3.09
5.8
2.9
kpa
8.9
8.5
—
10
29
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
6
8
7.71
3.08
1.5
1.4
—
—
—
0
0
(3035947) Staphylolysin Ab [Units/volume] in Serum
6
8
7.71
3.08
1.7
1.0
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
7
12
6.02
3.05
1.0
1.1
—
—
—
0
0
(4035726)
26
131
2.15
2.94
1.8
1.3
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
6
9
6.85
2.89
1.5
1.3
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
9
23
4.06
2.81
1.8
3.3
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
13
48
2.84
2.78
1.7
1.4
—
—
—
0
0
(3047189) Immunofixation for 24 hour Urine
5
6
8.52
2.76
1.2
2.0
—
—
—
0
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
5
6
8.52
2.76
2.6
2.0
ug/l
115.4
76.0
—
5
6
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
75
543
1.66
2.71
10.8
3.9
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
63
436
1.69
2.70
3.3
2.9
ng/l
4799.2
1249.2
0.78
53
364
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
78
573
1.64
2.64
2.1
2.0
pmol/l
93.0
96.3
0.21
41
305
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
8
20
4.14
2.60
1.5
1.1
—
—
—
0
0
(3001964) Herpes simplex virus Ag [Presence] in Specimen
5
7
7.31
2.56
1.0
1.4
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
6
11
5.60
2.56
1.2
1.0
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
57
390
1.68
2.52
9.4
3.4
—
—
—
0
0
(4268621)
7
16
4.51
2.50
2.3
1.8
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
8
21
3.94
2.49
1.3
1.3
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
6
12
5.13
2.42
1.0
1.2
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
12
47
2.66
2.32
1.3
1.2
—
—
—
0
0
(3019060) Gas panel - Arterial blood
21
107
2.09
2.32
4.6
8.3
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
12
48
2.61
2.23
1.3
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
12
48
2.61
2.23
1.3
1.2
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
12
48
2.61
2.23
3.8
1.8
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
46
307
1.67
2.21
12.4
4.9
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
17
81
2.21
2.21
1.8
1.1
u/ml
798.9
443.7
0.20
17
73
(3045414) Leukocytes [Presence] in Urine
13
55
2.47
2.18
2.6
1.8
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
6
14
4.39
2.17
2.5
4.2
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
5
10
5.11
2.08
1.4
1.1
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
5
10
5.11
2.08
1.4
1.1
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
5
10
5.11
2.08
1.4
1.1
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
19
98
2.05
2.04
2.1
1.5
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
7
21
3.42
1.98
2.0
1.1
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
16
78
2.15
1.98
13.7
4.4
%
54.2
53.2
0.05
16
78
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
5
11
4.64
1.95
1.4
1.1
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
5
11
4.64
1.95
1.4
1.1
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
5
11
4.64
1.95
1.4
1.1
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
6
16
3.84
1.95
1.5
1.2
—
—
—
0
0
(3000492) Spirometry study
22
122
1.92
1.95
1.8
1.5
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
52
371
1.57
1.89
10.3
3.9
estimate
0.0
0.0
0.00
19
117
(3008037) Lactate [Moles/volume] in Venous blood
10
40
2.59
1.87
6.2
4.1
mmol/l
1.2
1.6
—
10
40
(3000093) Morphology [Interpretation] in Blood Narrative
6
17
3.61
1.85
1.5
1.3
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
12
53
2.35
1.85
4.1
3.4
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
5
12
4.25
1.83
1.2
1.1
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
5
12
4.25
1.83
1.0
1.0
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
11
47
2.43
1.81
3.7
1.7
—
—
—
0
0
(4306422)
6
18
3.41
1.76
1.0
1.1
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
5
14
3.64
1.62
1.6
1.2
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
5
14
3.64
1.62
1.6
4.5
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
35
486
0.65
1.46
4.3
3.1
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
15
81
1.93
1.45
1.2
1.3
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
6
22
2.78
1.44
1.0
1.0
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
28
184
1.62
1.43
2.3
1.5
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
9
40
2.31
1.42
6.8
4.1
mmol/l
6.4
7.4
—
9
40
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
7
29
2.47
1.40
1.1
1.1
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
7
29
2.47
1.40
4.6
2.2
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
6
23
2.66
1.38
1.5
1.5
—
—
—
0
0
(3019225) pH of Specimen
21
129
1.71
1.37
21.2
4.6
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
70
566
1.39
1.30
2.7
2.1
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
18
2.83
1.29
1.2
1.2
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
5
18
2.83
1.29
1.2
1.7
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
14
81
1.79
1.12
17.0
4.5
—
—
—
0
0
(3002256) Pathology report gross observation
27
188
1.51
1.09
1.7
1.3
—
—
—
0
0
(4094501)
7
33
2.17
1.07
1.0
1.2
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
5
107
0.45
1.05
1.0
1.3
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
5
22
2.31
1.04
1.6
1.2
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
69
576
1.32
1.00
5.3
3.8
ng/l
126.2
42.0
0.72
57
407
(3044290) Cell count panel - Cerebral spinal fluid
6
27
2.26
0.94
2.0
1.2
—
—
—
0
0
(3013512) EKG study
52
425
1.32
0.86
5.8
4.1
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
17
113
1.56
0.86
9.9
3.7
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
45
362
1.32
0.83
1.6
1.5
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
150
1412
1.38
0.83
49.7
14.5
mg/l
25.6
24.5
0.18
143
1118
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
9
53
1.73
0.77
5.8
5.5
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
7
118
0.58
0.70
1.1
1.4
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
29
226
1.34
0.67
1.2
1.2
iu/ml
26.9
37.1
0.46
11
77
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
127
1350
0.80
0.66
4.9
4.7
mmol/l
5.9
6.0
0.17
118
1224
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
5
30
1.69
0.62
1.8
1.4
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
21
0.00
0.60
0.0
1.6
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method
0
23
0.00
0.58
0.0
2.2
—
34.9
—
0
8
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
32
389
0.78
0.57
4.0
4.3
%
27.5
21.7
0.84
17
192
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
6
38
1.60
0.55
1.0
1.3
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
121
1283
0.82
0.54
5.6
4.6
mu/l
2.0
1.9
0.08
114
1142
(3025941) Bacteria identified in Stool by Culture
12
83
1.48
0.53
1.8
1.2
—
—
—
0
0
(3020891) Body temperature
9
63
1.45
0.53
7.9
4.4
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
22
171
1.33
0.53
2.3
4.7
ug/l
3.9
68.0
0.83
17
149
(36660697) Celiac disease serology panel - Serum
15
109
1.41
0.53
1.1
1.1
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
97
892
1.19
0.52
3.9
2.9
u/l
70.6
50.4
0.66
91
835
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
7
45
1.58
0.49
1.4
1.4
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
19
147
1.33
0.47
1.8
2.4
g/l
0.2
0.2
0.66
19
134
(3042111) Morphology [Interpretation] in Bone marrow Narrative
5
31
1.63
0.43
1.2
1.5
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
5
32
1.58
0.42
4.8
2.0
—
—
—
0
0
(3044889) 12 lead EKG panel
105
983
1.16
0.42
4.3
4.0
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
5
33
1.53
0.41
1.0
1.4
—
—
—
0
0
(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose
0
17
0.00
0.41
0.0
1.1
—
7.3
—
0
9
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
(40768793) Breast Pathology biopsy report
5
35
1.44
0.39
1.0
1.3
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
5
35
1.44
0.39
1.4
1.3
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
132
1264
1.17
0.37
53.1
15.4
%
35.2
39.8
5.16
93
897
(4010399)
15
119
1.28
0.33
2.0
1.4
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
7
55
1.28
0.30
1.1
1.0
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
14
112
1.27
0.29
2.1
1.7
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
21
178
1.20
0.27
1.6
1.4
—
—
—
0
0
(3022621) pH of Urine by Test strip
13
105
1.26
0.25
5.2
2.4
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
136
1398
0.89
0.24
6.4
5.1
mmol/l
2.7
2.7
0.06
131
1277
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
127
1309
0.90
0.23
5.6
4.1
mmol/l
1.4
1.3
1.05
120
1187
(3022145) Colonoscopy Study observation
14
167
0.82
0.22
1.1
1.3
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
132
1282
1.11
0.22
7.7
6.1
mmol/mol
37.4
40.2
4.44
127
1186
(1617658) Protocol used for examination of sentinel lymph nodes
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3000012) Reticulocyte production index
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay
0
10
0.00
0.21
0.0
1.7
—
25.4
—
0
10
(3020191) Ethanol [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.1
—
1.7
—
0
7
(40768441) Liver Pathology biopsy report
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
12
144
0.82
0.20
1.4
2.4
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
28
254
1.12
0.17
1.5
1.5
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
16
139
1.17
0.17
1.5
1.7
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
88
846
1.08
0.16
3.4
2.8
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
75
0.79
0.16
1.3
1.0
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
133
1358
0.92
0.15
6.2
4.5
mmol/l
1.5
1.5
0.39
128
1241
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
107
1040
1.07
0.14
4.9
3.8
pmol/l
14.8
14.8
0.07
99
922
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
134
1365
0.93
0.13
6.2
4.5
mmol/l
4.6
4.6
0.07
128
1254
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
130
1322
0.94
0.10
41.5
13.8
ml/min/173m2
60.7
79.6
7.19
117
1065
(1002224) Polysomnography panel
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
81
0.86
0.07
1.0
1.2
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
12
132
0.90
0.07
1.3
2.2
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
33
321
1.03
0.02
1.3
1.2
u/ml
1.0
0.9
—
6
76
(40768797) Stomach Pathology biopsy report
18
188
0.95
0.02
1.4
1.3
—
—
—
0
0
(3003338) MCHC [Mass/volume]
119
1186
1.01
0.00
63.0
19.1
g/l
328.7
332.3
4.02
119
1180
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
18
185
0.97
0.00
18.5
8.1
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
7
0.00
0.00
0.0
1.0
—
6.8
—
0
7
(3044007) Cell count panel - Peritoneal fluid
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
30.3
—
0
7
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3010838) Calcium [Moles/time] in 24 hour Urine
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3006653) Thiamine [Moles/volume] in Blood
0
6
0.00
0.00
0.0
1.2
—
115.8
—
0
6
(3020491) Glucose [Moles/volume] in Blood
0
7
0.00
0.00
0.0
2.4
—
6.4
—
0
7
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3034988) Calcium [Moles/volume] in Capillary blood
0
7
0.00
0.00
0.0
2.0
—
1.2
—
0
7
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
8.6
—
0.7
—
0
7
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4198724)
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
147
1470
1.00
0.00
41.1
13.9
—
—
—
0
0
(3043410) Blood group antigens tested for on Red Blood Cells
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood
0
5
0.00
0.00
0.0
2.2
—
1.2
—
0
5
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3017315) Amylase [Enzymatic activity/volume] in Urine
0
5
0.00
0.00
0.0
1.0
—
108.0
—
0
5
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
8
0.00
-0.00
0.0
17.0
—
1295.1
—
0
8
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
8
0.00
-0.00
0.0
13.4
—
715.9
—
0
8
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
8
0.00
-0.00
0.0
3.0
—
14.1
—
0
8

Mortality – FinRegistry

Association

Association between endpoint M13_HYPERANG and mortality.

Females

Parameter HR [95% CI] p-value
M13_HYPERANG 3.134 [2.31, 4.24] < 0.001
Birth year 0.994 [0.99, 1.0] 0.178

During the follow-up period (1.1.1998 — 31.12.2019), 120 out of 383 females with M13_HYPERANG died.

Males

Parameter HR [95% CI] p-value
M13_HYPERANG 2.479 [1.81, 3.4] < 0.001
Birth year 0.99 [0.98, 1.0] 0.032

During the follow-up period (1.1.1998 — 31.12.2019), 118 out of 304 males with M13_HYPERANG died.

Mortality risk

Mortality risk for people of age

years, who have M13_HYPERANG.

N-year risk Females Males
1 0.298% 0.555%
5 1.629% 3.059%
10 4.34% 7.777%
15 7.969% 14.342%
20 13.634% 23.512%

Relationships between endpoints

Index endpoint: M13_HYPERANG – Hypersensitivity angiitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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