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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Lung transplantation

LUNG_TRANSPLANT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Operations: NOMESCO codes ^GDG0[0|3]|^GDG[0|3]|^GDG96|^FQB00|^FQB[1|2|3]0

1 out of 7 registries used, show all original rules.

7

4. Check minimum number of events

None

7

5. Include endpoints

None

7

6. Filter based on genotype QC (FinnGen only)

7

Control definitions (FinnGen only)

Control exclude
COPD_INSUFFICIENCY

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 45 23 22
Only index persons 29 15 14
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population - 47.06 50.97
Only index persons 46.23 45.59 46.91

-FinnGen-

Key figures

All Female Male
Number of individuals 7 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 33.62 - -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3010375) cycloSPORINE [Mass/volume] in Blood
7
0
+∞
9.38
29.7
0.0
ug/l
100.7
—
—
7
0
(3033658) Prothrombin time (PT) actual/Normal
7
12
+∞
4.68
18.1
3.7
%
84.0
104.4
—
7
12
(36304419) Bacteria [Presence] in Urine
7
17
+∞
3.84
11.1
3.1
—
—
—
0
0
(40758558) Short blood count panel - Blood
7
18
+∞
3.70
15.9
8.2
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
7
20
+∞
3.43
11.1
3.0
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
7
21
+∞
3.31
13.0
3.5
e6/l
3.4
3.5
—
7
15
(42870588) Differential panel, method unspecified - Blood
7
21
+∞
3.31
17.1
6.4
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
7
35
+∞
1.85
27.0
12.6
e9/l
4.2
4.0
—
7
30
(3044889) 12 lead EKG panel
7
36
+∞
1.81
10.4
3.0
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
7
40
+∞
1.41
15.3
4.1
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
0
24
0.00
1.04
0.0
2.1
—
—
—
0
0
(3003338) MCHC [Mass/volume]
7
50
+∞
0.74
91.1
15.3
g/l
324.3
334.6
—
7
50
(3002385) Erythrocyte distribution width [Ratio]
7
50
+∞
0.74
90.3
12.3
%
14.4
13.3
—
7
50
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
0
18
0.00
0.72
0.0
2.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
15
0.00
0.48
0.0
2.1
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
0
15
0.00
0.48
0.0
1.7
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
7
53
+∞
0.47
93.1
12.2
%
39.6
42.7
—
7
43
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
7
56
+∞
0.47
78.7
10.2
mg/l
26.1
17.7
—
7
44
(40760892) CBC W Ordered Manual Differential panel - Blood
0
11
0.00
0.23
0.0
3.8
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
0
10
0.00
0.23
0.0
1.1
—
1.6
—
0
10
(3020564) Creatinine [Moles/volume] in Serum or Plasma
7
60
+∞
0.23
90.0
10.5
umol/l
77.7
72.0
—
7
60
(3021879) Hepatitis B virus core Ab [Presence] in Serum
0
10
0.00
0.23
0.0
1.8
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
0
12
0.00
0.23
0.0
1.1
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
9
0.00
0.23
0.0
1.3
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
0
9
0.00
0.23
0.0
1.4
—
—
—
0
0
(3013512) EKG study
0
13
0.00
0.23
0.0
1.5
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
0
7
0.00
0.00
0.0
5.6
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019225) pH of Specimen
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint LUNG_TRANSPLANT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have LUNG_TRANSPLANT.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: LUNG_TRANSPLANT – Lung transplantation

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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