Other contact dermatitis

L12_OTHERCONTACT

contact dermatitis: An inflammatory skin condition caused by direct contact between the skin and either an irritating substance or an allergen.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L24, L25
  • Hospital discharge: ICD-9 692
  • Hospital discharge: ICD-8 692[1-6]|69281
  • Hospital discharge: excluded ICD-9 6920B|6921B|6922B|6924B|6924D|6924H|6924L|6925B|6925D|6926B|6926D
  • Hospital discharge: excluded ICD-8 6925
  • Cause of death: ICD-10 L24, L25
  • Cause of death: ICD-9 692
  • Cause of death: ICD-8 692[1-6]|69281
  • Cause of death: excluded ICD-9 6920B|6921B|6922B|6924B|6924D|6924H|6924L|6925B|6925D|6926B|6926D
  • Cause of death: excluded ICD-8 6925

2 out of 7 registries used, show all original rules.

3190

4. Check minimum number of events

None

3190

5. Include endpoints

None

3190

6. Filter based on genotype QC (FinnGen only)

3078

Control definitions (FinnGen only)

Control exclude
L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 34509 20117 14037
Only index persons 27113 16838 10275
Unadjusted period prevalence (%)
Whole population 0.50 0.58 0.39
Only index persons 0.53 0.62 0.39
Median age at first event (years)
Whole population 43.75 43.86 43.20
Only index persons 38.73 39.87 36.87

-FinnGen-

Key figures

All Female Male
Number of individuals 3078 1960 1118
Unadjusted period prevalence (%) 0.69 0.77 0.56
Median age at first event (years) 41.39 39.66 44.44

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3190
Matched controls
31900
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
+∞
323.0
330
*
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
+∞
323.0
381
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
10.8
323.0
1155
1585
6929X
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[DERMATITITIS ARTEFACTA NUD]
+∞
323.0
329
*
L24.9
ICD-10 Finland
Irritant contact dermatitis, unspecified cause
423.1
323.0
505
14
L20.0
ICD-10 Finland
Besnier prurigo
+∞
323.0
531
*
XQ800
NOMESCO Finland
Prick test
11.0
323.0
690
778
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
17.2
323.0
1092
936
D07AC01
ATC
betamethasone; topical
4.8
323.0
1634
5754
XQ802
NOMESCO Finland
Epicutan test
102.9
323.0
821
107
D07AC13
ATC
mometasone; topical
5.2
323.0
1549
4894
L25.9
ICD-10 Finland
Unspecified contact dermatitis, unspecified cause
187.8
323.0
452
28
E0000UV
ATC
NA
5.5
323.0
1953
7126
L24.0
ICD-10 Finland
Irritant contact dermatitis due to detergents
5566.5
323.0
486
*
L24.8
ICD-10 Finland
Irritant contact dermatitis due to other agents
2164.8
323.0
363
*
E000001
ATC
NA
5.0
285.3
1113
3067
69240
ICD-8 Finland
Other eczema and dermatitis, Due to other chemicals
+∞
209.7
199
*
L30.3
ICD-10 Finland
Infective dermatitis
27.0
202.5
284
115
D07BC01
ATC
betamethasone and antiseptics; topical
5.3
200.5
691
1578
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
391.6
186.7
186
5
D07AB02
ATC
hydrocortisone butyrate; topical
3.3
176.7
1186
4870
L23.5
ICD-10 Finland
Allergic contact dermatitis due to other chemical products
346.6
165.7
166
5
D07AD01
ATC
clobetasol; topical
4.2
164.2
724
2087
D07AB08
ATC
desonide; topical
5.3
163.3
548
1191
E000002
ATC
NA
4.7
158.7
614
1553
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
148.0
146.7
155
11
D07AA02
ATC
hydrocortisone; topical
3.8
126.3
606
1840
L20
ICD-10 Finland
Atopic dermatitis
+∞
119.5
114
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.9
118.8
558
1656
D07CC01
ATC
betamethasone and antibiotics; topical
3.6
118.2
607
1941
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
173.4
112.1
117
7
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
+∞
111.1
106
*
E000006
ATC
NA
5.0
109.1
377
826
E000003
ATC
NA
7.3
106.6
271
402
D07BA04
ATC
hydrocortisone and antiseptics; topical
4.0
104.7
465
1304
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
+∞
103.7
99
*
D02AE01
ATC
carbamide; topical
5.2
101.6
339
712
N05BB01
ATC
hydroxyzine; systemic
5.0
101.6
355
785
69230
ICD-8 Finland
Other eczema and dermatitis, Due to drugs
+∞
94.2
90
*
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
46.3
91.2
112
25
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
+∞
91.1
87
*
L24.5
ICD-10 Finland
Irritant contact dermatitis due to other chemical products
174.5
81.5
85
5
E000007
ATC
NA
5.1
80.5
272
575
H02AB06
ATC
prednisolone; systemic
2.0
76.9
1496
9660
TQW80
NOMESCO Finland
Local dermatologic skincare
11.4
74.8
144
132
R06AE07
ATC
cetirizine; oral
2.0
74.7
1460
9408
L25.8
ICD-10 Finland
Unspecified contact dermatitis due to other agents
+∞
73.2
70
*
D07AC14
ATC
methylprednisolone aceponate; topical
5.0
72.6
249
534
69282
ICD-8 Finland
Other eczema and dermatitis, E microbis
+∞
72.1
69
*
6929A
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA NUMMULARE]
+∞
70.0
67
*
L30.0
ICD-10 Finland
Nummular dermatitis
9.6
67.5
142
154
D11AH01
ATC
tacrolimus; topical
671.8
67.2
66
*
E000004
ATC
NA
8.8
66.2
146
172
L23.1
ICD-10 Finland
Allergic contact dermatitis due to adhesives
328.5
64.7
65
*
L30.8
ICD-10 Finland
Other specified dermatitis
11.0
62.0
121
114
D09AB01
ATC
zinc bandage without supplements; topical
13.3
60.6
108
84
L20.8
ICD-10 Finland
Other atopic dermatitis
+∞
57.5
55
*
D07XC01
ATC
betamethasone, combinations; topical
2.7
55.7
417
1668
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.1
49.8
711
3898
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.1
49.6
291
989
J01DA01
ATC
[U] cefalexin; systemic
1.7
46.2
1972
15467
D07AB01
ATC
clobetasone; topical
4.7
45.9
162
357
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
45.7
44.2
54
12
6923B
ICD-9 Finland
Contact dermatitis and other eczema, Due to drugs and medicines in contact with skin[DERMATITIS ARTEFACTA E PHARMACIS ALLERGICA]
+∞
43.8
42
*
D07XB05
ATC
dexamethasone, combinations; topical
5.3
42.3
133
258
6928X
ICD-9 Finland
Contact dermatitis and other eczema, Due to other specified agents[MUU KOSKETUSIHOTTUMA]
+∞
41.7
40
*
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
55.2
41.5
49
9
WQ007
NOMESCO Finland
NA
412.6
41.2
41
*
L30.1
ICD-10 Finland
Dyshidrosis [pompholyx]
46.1
41.0
50
11
L24.3
ICD-10 Finland
Irritant contact dermatitis due to cosmetics
+∞
37.6
36
*
J01DB01
ATC
cefalexin; oral
1.7
37.4
2481
21329
R06AX27
ATC
desloratadine; oral
1.8
36.6
835
5329
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
+∞
36.5
35
*
D02AX
ATC
Other emollients and protectives
4.7
34.5
120
261
J01FF01
ATC
clindamycin; systemic
1.7
33.9
800
5136
R06AE09
ATC
levocetirizine; oral
2.0
33.8
456
2403
D05BB02
ATC
acitretin; oral
5.6
33.8
101
185
L24.1
ICD-10 Finland
Irritant contact dermatitis due to oils and greases
+∞
33.4
32
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.5
33.2
281
1189
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.0
32.8
137
356
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.1
32.7
410
2094
S87
ICPC
Dermatitis/atopic eczema
6.1
32.5
90
150
L25.0
ICD-10 Finland
Unspecified contact dermatitis due to cosmetics
320.1
31.9
32
*
XQ848
NOMESCO Finland
Dermatological photography
5.5
31.9
97
182
6918C
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[DIATHESIS (CONSTITUTIO) ATOPICA]
+∞
30.2
29
*
D07CB01
ATC
triamcinolone and antibiotics; topical
5.0
30.2
99
202
D11AX14
ATC
[U] tacrolimus; topical
+∞
29.2
28
*
6920A
ICD-9 Finland
Contact dermatitis and other eczema, Due to detergents[DERMATITIS ARTEFACTA E DETERGENTIBUS TOXICA]
+∞
28.2
27
*
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
10.5
27.7
54
52
L28.1
ICD-10 Finland
Prurigo nodularis
100.9
27.7
30
*
L24
ICD-10 Finland
Irritant contact dermatitis
32.1
26.8
35
11
L25.3
ICD-10 Finland
Unspecified contact dermatitis due to other chemical products
273.2
26.7
27
*
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
25.7
807
5543
H02AB04
ATC
methylprednisolone; systemic
1.9
25.6
412
2308
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
25.5
486
2884
WZC30
NOMESCO Finland
Teaching
2.0
25.3
369
1993
M54.5
ICD-10 Finland
Low back pain
1.6
25.3
940
6727
L25.1
ICD-10 Finland
Unspecified contact dermatitis due to drugs in contact with skin
131.0
24.6
26
*
A46
ICD-10 Finland
Erysipelas
2.0
24.4
356
1922
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
3.6
24.2
112
319
L23
ICD-10 Finland
Allergic contact dermatitis
15.2
23.7
39
26
SPAT1263
SPAT
Sampling
1.5
23.3
1216
9355
6928B
ICD-9 Finland
Contact dermatitis and other eczema, Due to other specified agents[DERMATITIS ARTEFACTA E COSMETICA ALLERGICA]
+∞
22.9
22
*
R06AX22
ATC
ebastine; oral
1.7
22.7
495
3055
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
22.7
529
3333
R03AC02
ATC
salbutamol; inhalant
1.5
22.4
1492
12030
L28.0
ICD-10 Finland
Lichen simplex chronicus
14.4
22.1
37
26
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
22.0
335
1834
6924B
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E METALLIS ALLERGICA]
+∞
21.9
21
*
SPAT1301
SPAT
No procedures
1.5
21.9
860
6196
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
21.6
1129
8646
L50.3
ICD-10 Finland
Dermatographic urticaria
5.6
21.4
63
115
H02AB07
ATC
prednisone; oral
1.8
20.9
397
2343
T78.4
ICD-10 Finland
Allergy, unspecified
2.6
20.5
151
593
R06AX13
ATC
loratadine; oral
1.7
20.5
438
2685
6961A
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PSORIASIS VULGARIS]
17.0
20.4
32
19
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.9
20.1
294
1586
6924N
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E CHEMICALIBUS ALIIS ALLERGICA]
+∞
19.8
19
*
L24.6
ICD-10 Finland
Irritant contact dermatitis due to food in contact with skin
+∞
19.8
19
*
L26
ICD-10 Finland
Exfoliative dermatitis
+∞
19.8
19
*
J01AA07
ATC
tetracycline; systemic
1.7
19.8
449
2800
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
19.6
1261
10009
SPAT1153
SPAT
Removal of sutures
1.5
19.6
826
6018
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.9
19.2
121
431
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
10.4
19.1
37
36
WQ020
NOMESCO Finland
NA
55.3
18.9
22
*
SPAT1260
SPAT
Consultation of another employee
1.7
18.9
476
3052
L24.4
ICD-10 Finland
Irritant contact dermatitis due to drugs in contact with skin
191.0
18.5
19
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
18.5
210
1022
N02AX02
ATC
tramadol; systemic, rectal
1.4
18.4
1102
8599
D05AX02
ATC
calcipotriol; topical
2.8
18.4
118
427
N02BE01
ATC
paracetamol; systemic, rectal
1.5
17.7
2503
22742
C01CA24
ATC
epinephrine; parenteral
2.2
17.7
181
842
D05AX52
ATC
calcipotriol, combinations; topical
2.5
17.7
142
585
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
9.8
17.6
35
36
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.9
17.5
252
1350
S18
ICPC
Laceration/cut
1.4
17.5
1051
8188
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
17.5
573
3929
A02BC02
ATC
pantoprazole; systemic
1.4
17.3
1778
15212
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
16.9
603
4209
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
16.6
344
2082
WQ021
NOMESCO Finland
NA
27.7
16.5
22
8
M25.5
ICD-10 Finland
Pain in joint
1.5
16.4
770
5699
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
16.4
972
7528
L25
ICD-10 Finland
Unspecified contact dermatitis
23.1
16.4
23
10
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
15.8
1086
8628
S29
ICPC
Skin symptom/complaint other
1.6
15.6
401
2576
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
4.9
15.5
50
103
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
6.2
15.4
41
67
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
15.2
525
3633
ZXX04
NOMESCO Finland
Extent of procedure, 4 units
9.2
15.2
31
34
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
15.1
817
6206
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.3
14.7
140
628
D07AC03
ATC
desoximetasone; topical
3.8
14.7
62
166
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
14.7
706
5236
ZXX03
NOMESCO Finland
Extent of procedure, 3 units
7.5
14.7
34
46
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
14.6
723
5387
4779A
ICD-9 Finland
Allergic rhinitis, Cause unspecified
5.6
14.6
42
76
6925X
ICD-9 Finland
Contact dermatitis and other eczema, Due to food in contact with skin[DERMATITIS ARTEFACTA EX ALIMENTIS NUD]
+∞
14.6
14
*
6927F
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[ERUPTIO POLYMORPHICA SOLARIS]
+∞
14.6
14
*
D11AH02
ATC
pimecrolimus; topical
+∞
14.6
14
*
D01AC02
ATC
miconazole; topical
2.0
14.5
202
1068
XQ817
NOMESCO Finland
NA
36.2
14.4
18
5
134
Kela drug reimbursment
General erythroderma
15.4
14.4
23
15
R06.0
ICD-10 Finland
Dyspnoea
1.5
14.2
594
4280
R03AC03
ATC
terbutaline; inhalant
1.6
14.2
364
2338
SPAT1310
SPAT
Counselling related to known health issue
1.4
14.2
838
6456
L29.9
ICD-10 Finland
Pruritus, unspecified
4.2
14.1
53
128
UJF32
NOMESCO Finland
Coloscopy
1.5
14.1
622
4531
J45.8
ICD-10 Finland
Mixed asthma
2.8
14.0
87
311
Z00.0
ICD-10 Finland
General medical examination
1.5
13.9
466
3197
0350X
ICD-9 Finland
Erysipelas[ERYSIPELAS ALIA DEFINITA SEU NUD]
5.2
13.9
42
81
J01FA01
ATC
erythromycin; systemic
1.6
13.8
399
2641
501
Kela drug reimbursment
Cow's milk and / or soy protein allergy in young children
10.5
13.7
26
25
N03AX12
ATC
gabapentin; oral
1.6
13.6
386
2542
SPAT1254
SPAT
Administration of medicine
1.6
13.6
359
2322
L27.2
ICD-10 Finland
Dermatitis due to ingested food
75.4
13.6
15
*
4540A
ICD-9 Finland
Varicose veins of lower extremities, With ulcer
14.7
13.6
22
15
D11AX15
ATC
[U] pimecrolimus; topical
+∞
13.5
13
*
S88
ICPC
Dermatitis contact/allergic
3.5
13.4
61
175
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
13.2
451
3104
R03BA02
ATC
budesonide; inhalant
1.5
12.9
438
3010
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.5
12.8
553
4003
SPAT1211
SPAT
Application of soft bandage
1.8
12.7
230
1334
J01AA02
ATC
doxycycline; systemic
1.3
12.6
2208
20001
L25.4
ICD-10 Finland
Unspecified contact dermatitis due to food in contact with skin
+∞
12.5
12
*
69220
ICD-8 Finland
Other eczema and dermatitis, E solventibus, professionalis
+∞
12.5
12
*
6925A
ICD-9 Finland
Contact dermatitis and other eczema, Due to food in contact with skin[DERMATITIS ARTEFACTA EX ALIMENTIS TOXICA (VÄLITÖN)]
+∞
12.5
12
*
L24.2
ICD-10 Finland
Irritant contact dermatitis due to solvents
130.5
12.4
13
*
SPAT1312
SPAT
General health counselling
1.4
12.4
831
6516
N03AX16
ATC
pregabalin; oral
1.4
12.2
580
4273
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
12.1
305
1946
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
11.9
337
2216
J30.3
ICD-10 Finland
Other allergic rhinitis
2.4
11.8
102
441
G47.3
ICD-10 Finland
Sleep apnoea
1.5
11.8
486
3483
S97
ICPC
Chronic ulcer skin
2.2
11.6
119
556
69200
ICD-8 Finland
Other eczema and dermatitis, Due to detergents
19.0
11.6
17
9
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
2.9
11.6
69
242
68600
ICD-8 Finland
Other local infections of skin and subcutaneous tissue, Pyoderma
23.0
11.6
16
7
D11
ICPC
Diarrhoea
1.6
11.5
287
1828
L23.4
ICD-10 Finland
Allergic contact dermatitis due to dyes
120.4
11.4
12
*
SPAT1283
SPAT
Restricted health certificate
1.5
11.4
499
3614
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
11.4
169
917
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
3.3
11.3
55
168
R06AX18
ATC
acrivastine; oral
2.6
11.3
82
322
L29.8
ICD-10 Finland
Other pruritus
5.1
11.2
34
67
R51.80
ICD-10 Finland
Headache
1.5
11.1
377
2586
R03BA05
ATC
fluticasone; inhalant
1.5
11.0
457
3275
J01FA06
ATC
roxithromycin; oral
1.3
11.0
1069
8845
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
10.9
258
1619
WZA90
NOMESCO Finland
Other doctors statement
1.4
10.8
577
4338
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
10.7
1967
17694
J45
ICD-10 Finland
Asthma
1.7
10.7
234
1434
R03DC03
ATC
montelukast; oral
1.5
10.6
395
2765
M03BX02
ATC
tizanidine; oral
1.3
10.6
1723
15251
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
3.9
10.5
42
109
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
10.5
413
2929
69219
ICD-8 Finland
Other eczema and dermatitis, Ex oleis et unguentis, professionali non indicata
+∞
10.4
10
*
Y1203
ICD-8 Finland
NA
+∞
10.4
10
*
L25.2
ICD-10 Finland
Unspecified contact dermatitis due to dyes
+∞
10.4
10
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
10.4
342
2332
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
10.4
406
2874
WIX00
NOMESCO Finland
Allergy cleanup guidance
32.6
10.3
13
*
L50.9
ICD-10 Finland
Urticaria, unspecified
2.3
10.2
89
387
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
10.2
1423
12317
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
10.2
1035
8588
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
10.2
169
955
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
10.2
390
2747
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
10.0
413
2952
H16.0
ICD-10 Finland
Corneal ulcer
2.1
10.0
115
567
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
10.0
1008
8351
R03AC12
ATC
salmeterol; inhalant
2.1
10.0
112
546
L23.7
ICD-10 Finland
Allergic contact dermatitis due to plants, except food
40.2
10.0
12
*
XQ818
NOMESCO Finland
Conjunctival allergen provocation test
16.7
9.9
15
9
M79.6
ICD-10 Finland
Pain in limb
1.3
9.8
884
7206
A02BC01
ATC
omeprazole; systemic
1.3
9.8
675
5290
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
9.7
291
1941
R01AD09
ATC
mometasone; nasal
1.3
9.7
1201
10220
Z01.2
ICD-10 Finland
Dental examination
1.3
9.6
1078
9055
SPAT1216
SPAT
Assessment of functional ability
1.5
9.5
333
2297
S76
ICPC
Skin infection other
2.0
9.5
115
579
L25.5
ICD-10 Finland
Unspecified contact dermatitis due to plants, except food
100.3
9.4
10
*
6924A
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E METALLIS TOXICA]
+∞
9.4
9
*
6983B
ICD-9 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus[NEURODERMATITIS CIRCUMSCRIPTA]
+∞
9.4
9
*
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
9.3
466
3456
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
9.2
162
934
D07XB01
ATC
flumetasone, combinations; topical
5.5
9.2
26
48
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
9.2
729
5829
R74
ICPC
Upper respiratory infection acute
1.3
9.2
751
6032
G44.2
ICD-10 Finland
Tension-type headache
1.5
9.2
329
2287
J46
ICD-10 Finland
Status asthmaticus
2.5
9.1
72
297
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
2.2
9.0
86
391
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
9.0
1760
15778
D11AH04
ATC
alitretinoin; oral
36.8
9.0
11
*
ZXX05
NOMESCO Finland
Extent of procedure, 5 units
9.0
9.0
18
20
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.0
1283
11080
SPAT1240
SPAT
Therapeutic discussion
1.5
8.9
270
1802
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
7.4
8.9
20
27
S01GX02
ATC
levocabastine; ophthalmic
1.8
8.9
157
907
R01AD08
ATC
fluticasone; nasal
1.3
8.8
726
5834
J20
ICD-10 Finland
Acute bronchitis
1.6
8.7
221
1415
L71.8
ICD-10 Finland
Other rosacea
3.9
8.7
34
88
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.7
1192
10234
D06BX01
ATC
metronidazole; topical
1.6
8.6
243
1597
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.5
1042
8813
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
8.4
439
3276
S21
ICPC
Skin texture symptom/complaint
1.5
8.4
264
1777
S02
ICPC
Pruritus
2.3
8.4
77
346
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
8.4
195
1220
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
8.4
612
4825
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
8.4
450
3374
L04AA01
ATC
[U] ciclosporin; systemic
3.5
8.3
37
107
M13.9
ICD-10 Finland
Arthritis, unspecified
1.7
8.3
163
972
M01AE02
ATC
naproxen; oral, rectal
1.2
8.3
1530
13570
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
8.2
649
5170
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.9
8.2
112
592
S06
ICPC
Rash localized
1.8
8.2
126
696
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
8.2
187
1166
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
2.7
8.2
52
191
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
8.2
290
2006
R01AD01
ATC
beclometasone; nasal
1.4
8.2
375
2737
49300
ICD-8 Finland
Asthma, bronchiale
2.5
8.1
61
249
1104A
ICD-9 Finland
Dermatophytosis, Of foot
17.2
8.1
12
7
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.8
8.0
143
830
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
8.0
254
1718
L50.0
ICD-10 Finland
Allergic urticaria
2.4
8.0
66
282
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
8.0
331
2365
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
8.0
537
4178
J01AA04
ATC
lymecycline; systemic
1.4
8.0
325
2314
L17
ICPC
Foot/toe symptom/complaint
1.3
7.9
561
4401
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
7.9
944
7947
D01AE15
ATC
terbinafine; topical
1.7
7.9
150
889
J01MA12
ATC
levofloxacin; systemic
1.4
7.7
418
3141
D05AX03
ATC
calcitriol; topical
3.5
7.7
34
99
R01AD12
ATC
fluticasone furoate; nasal
1.3
7.6
760
6249
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
7.6
986
8377
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.6
7.6
204
1329
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
7.6
90
453
A07AA02
ATC
nystatin; oral
1.7
7.6
137
801
L30.4
ICD-10 Finland
Erythema intertrigo
4.5
7.5
25
56
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.8
7.5
133
770
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
7.5
696
5664
D64.9
ICD-10 Finland
Anaemia, unspecified
1.6
7.5
205
1340
A03
ICPC
Fever
1.4
7.5
391
2917
N06AX21
ATC
duloxetine; oral
1.5
7.5
255
1752
R06AX26
ATC
fexofenadine; oral
1.7
7.5
162
997
SPAT1324
SPAT
Screening procedure
1.3
7.5
502
3899
N02AA05
ATC
oxycodone; systemic
1.5
7.5
297
2108
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
1.8
7.5
127
728
J01CE08
ATC
benzathine benzylpenicillin; parenteral
3.6
7.4
31
86
EBA00
NOMESCO Finland
Extraction of tooth
1.3
7.4
805
6692
D01AC03
ATC
econazole; topical
1.7
7.4
137
808
6927X
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[DERMATITIS PHOTOTOXICA NUD]
+∞
7.3
7
*
6989X
ICD-9 Finland
Pruritus and related conditions, Unspecified pruritic disorder
+∞
7.3
7
*
L13.0
ICD-10 Finland
Dermatitis herpetiformis
6.8
7.3
17
25
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.6
7.2
169
1061
K02.1
ICD-10 Finland
Caries of dentine
1.2
7.2
1514
13536
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.8
7.2
123
705
A02BC03
ATC
lansoprazole; oral
1.3
7.2
703
5756
J02AC02
ATC
itraconazole; systemic
1.4
7.2
427
3258
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
1.9
7.2
93
484
L30
ICD-10 Finland
Other dermatitis
2.6
7.1
47
179
C84.0
ICD-10 Finland
Mycosis fungoides
30.1
7.1
9
*
1101A
ICD-9 Finland
Dermatophytosis, Of nail
30.1
7.1
9
*
R96
ICPC
Asthma
1.6
7.1
188
1219
E66.01
ICD-10 Finland
Obesity due to excess calories
1.6
7.1
191
1243
Z30.2
ICD-10 Finland
Sterilization
1.5
7.1
271
1905
L08.0
ICD-10 Finland
Pyoderma
4.2
7.1
25
60
N05CF01
ATC
zopiclone; oral
1.3
7.1
773
6422
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
7.0
358
2658
K90.0
ICD-10 Finland
Coeliac disease
2.1
7.0
72
343
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.4
7.0
305
2203
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.6
7.0
194
1273
L85.3
ICD-10 Finland
Xerosis cutis
4.4
6.9
23
52
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.5
6.9
269
1897
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
6.9
1444
12883
RJ190
NOMESCO Finland
NA
13.8
6.9
11
8
S01GX05
ATC
lodoxamide; ophthalmic
3.0
6.8
36
120
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
1.8
6.8
110
618
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.5
6.8
203
1352
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
6.8
1002
8610
L85.9
ICD-10 Finland
Epidermal thickening, unspecified
8.3
6.8
14
17
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.5
6.8
249
1739
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.6
6.8
183
1193
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.6
6.8
164
1038
R32
ICD-10 Finland
Unspecified urinary incontinence
2.2
6.8
61
275
E000005
ATC
NA
16.7
6.7
10
6
J01CF02
ATC
cloxacillin; systemic
2.3
6.7
57
248
A05
ICPC
Feeling ill
1.7
6.7
136
823
R03AC13
ATC
formoterol; inhalant
1.8
6.7
113
646
K59.1
ICD-10 Finland
Functional diarrhoea
1.8
6.7
113
649
6860A
ICD-9 Finland
Other local infections of skin and subcutaneous tissue, Pyoderma
22.5
6.7
9
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
6.6
294
2128
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
6.6
391
2977
J01XC01
ATC
fusidic acid; systemic
3.1
6.6
33
106
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.7
6.6
135
818
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.1
6.6
74
365
R03BA01
ATC
beclometasone; inhalant
1.4
6.6
327
2415
EMB10
NOMESCO Finland
Tonsillectomy
1.7
6.6
141
864
D07AC09
ATC
budesonide; topical
8.7
6.5
13
15
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
6.5
698
5778
S01GX08
ATC
ketotifen; ophthalmic
1.9
6.5
88
467
-1
NOMESCO Finland
NA
1.2
6.5
845
7157
J02AC01
ATC
fluconazole; systemic
1.2
6.5
1070
9301
TAB00
NOMESCO Finland
Lumbar puncture
1.8
6.4
107
610
H03AA01
ATC
levothyroxine sodium; systemic
1.3
6.4
562
4531
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
6.4
582
4714
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.2
6.4
63
294
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
2.9
6.4
37
129
7083A
ICD-9 Finland
Urticaria, Dermatographic urticaria
70.0
6.4
7
*
395
Kela drug reimbursment
Dupilumab
70.0
6.4
7
*
D11AH05
ATC
dupilumab; topical
70.0
6.4
7
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.0
6.4
79
405
F45.8
ICD-10 Finland
Other somatoform disorders
1.6
6.4
173
1130
D82
ICPC
Teeth/gum disease
1.2
6.4
875
7448
L28.2
ICD-10 Finland
Other prurigo
14.3
6.4
10
7
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.6
6.4
45
177
C03CA01
ATC
furosemide; systemic
1.3
6.4
576
4664
WX290
NOMESCO Finland
Other blockade of nerve
1.2
6.4
1167
10247
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.5
6.3
193
1294
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.4
6.3
246
1738
45400
ICD-8 Finland
Varicose veins of lower extremities, With ulcer
6.5
6.3
15
23
B35.3
ICD-10 Finland
Tinea pedis
1.9
6.3
79
410
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.3
1798
16486
H01.0
ICD-10 Finland
Blepharitis
1.7
6.3
113
662
Z2221
NOMESCO Finland
Medical doctor
0.8
6.3
457
5678
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
6.3
214
1473
6930B
ICD-9 Finland
Dermatitis due to substances taken internally, Due to drugs and medicines[EXANTHEMA EX USU PHARMACIS]
+∞
6.2
6
*
69283
ICD-8 Finland
Other eczema and dermatitis, Dysidroticum (pompholyx)
+∞
6.2
6
*
6923A
ICD-9 Finland
Contact dermatitis and other eczema, Due to drugs and medicines in contact with skin[DERMATITIS ARTEFACTA E PHARMACIS TOXICA]
+∞
6.2
6
*
6900A
ICD-9 Finland
Erythematosquamous dermatosis[ECZEMA SEBORRHOICUM]
+∞
6.2
6
*
69288
ICD-8 Finland
Other eczema and dermatitis, E causis alii definitis
+∞
6.2
6
*
6939X
ICD-9 Finland
Dermatitis due to substances taken internally, Due to unspecified substance taken internally
+∞
6.2
6
*
6924D
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E CHEMICALIBUS GUMMI ALLERGICA]
+∞
6.2
6
*
69210
ICD-8 Finland
Other eczema and dermatitis, Ex oleis et unguentis, professionalis
+∞
6.2
6
*
M54.3
ICD-10 Finland
Sciatica
1.6
6.2
138
857
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.2
6.2
775
6528
M77.1
ICD-10 Finland
Lateral epicondylitis
1.5
6.2
181
1202
B02.9
ICD-10 Finland
Zoster without complication
1.7
6.2
110
642
L15
ICPC
Knee symptom/complaint
1.3
6.2
458
3608
L16
ICPC
Ankle symptom/complaint
1.5
6.1
218
1512
M79.7
ICD-10 Finland
Fibromyalgia
1.9
6.1
77
400
R51
ICD-10 Finland
Headache
1.7
6.1
118
707
D05AA
ATC
Tars
4.7
6.1
19
41
R02
ICPC
Shortness of breath/dyspnoea
1.4
6.1
254
1822
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
6.1
160
1041
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
6.0
507
4065
J31.0
ICD-10 Finland
Chronic rhinitis
1.5
6.0
176
1170
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.3
6.0
50
218
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
6.0
2630
25129
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
6.0
232
1637

Mortality – FinRegistry

Association

Association between endpoint L12_OTHERCONTACT and mortality.

Females

Parameter HR [95% CI] p-value
L12_OTHERCONTACT 1.083 [0.95, 1.23] 0.22
Birth year 0.995 [0.99, 1.0] 0.214

During the follow-up period (1.1.1998 — 31.12.2019), 581 out of 10345 females with L12_OTHERCONTACT died.

Males

Parameter HR [95% CI] p-value
L12_OTHERCONTACT 1.193 [1.06, 1.34] 0.003
Birth year 0.988 [0.98, 1.0] 0.012

During the follow-up period (1.1.1998 — 31.12.2019), 493 out of 4970 males with L12_OTHERCONTACT died.

Mortality risk

Mortality risk for people of age

years, who have L12_OTHERCONTACT.

N-year risk Females Males
1 0.094% 0.231%
5 0.58% 1.444%
10 1.461% 3.579%
15 2.911% 6.647%
20 5.288% 11.456%

Relationships between endpoints

Index endpoint: L12_OTHERCONTACT – Other contact dermatitis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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