Acute lymphadenitis

L12_LYMPHADENITIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L04
  • Hospital discharge: ICD-9 683
  • Hospital discharge: ICD-8 683
  • Cause of death: ICD-10 L04
  • Cause of death: ICD-9 683
  • Cause of death: ICD-8 683

2 out of 7 registries used, show all original rules.

2504

4. Check minimum number of events

None

2504

5. Include endpoints

None

2504

6. Filter based on genotype QC (FinnGen only)

2504

Control definitions (FinnGen only)

Control exclude
L12_INFECT_SKIN

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L00-L08
Name in latin
Lymphadenitis acuta

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 27936 12727 15117
Only index persons 24318 11304 13014
Unadjusted period prevalence (%)
Whole population 0.39 0.36 0.42
Only index persons 0.46 0.42 0.50
Median age at first event (years)
Whole population 18.02 22.26 14.28
Only index persons 18.72 22.85 15.14

-FinnGen-

Key figures

All Female Male
Number of individuals 2504 1478 1026
Unadjusted period prevalence (%) 0.48 0.50 0.45
Median age at first event (years) 28.96 29.51 28.16

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2288
Matched controls
22882
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
1212.1
323.0
1219
21
68300
ICD-8 Finland
Acute lymphadenitis, Colli
+∞
323.0
308
*
6830A
ICD-9 Finland
Acute lymphadenitis[LYMPHADENITIS ACUTA COLLI]
+∞
202.1
191
*
L04.9
ICD-10 Finland
Acute lymphadenitis, unspecified
352.5
192.5
192
6
EP1AE
NOMESCO Finland
Neck ultrasound examination
7.5
126.9
322
491
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
20.0
99.3
152
81
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
6.9
70.8
185
287
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
6.3
69.8
197
339
68302
ICD-8 Finland
Acute lymphadenitis, Inguinis
+∞
63.8
61
*
PJA10
NOMESCO Finland
Exploration of lymph nodes
15.8
62.1
103
68
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
12.9
61.9
112
91
L04.3
ICD-10 Finland
Acute lymphadenitis of lower limb
293.8
56.5
57
*
L04.2
ICD-10 Finland
Acute lymphadenitis of upper limb
135.6
50.0
53
*
L02.1
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of neck
30.8
49.5
66
22
J01DB01
ATC
cefalexin; oral
2.2
47.2
1875
15522
68309
ICD-8 Finland
Acute lymphadenitis, Unspecified
+∞
44.9
43
*
6832A
ICD-9 Finland
Acute lymphadenitis[LYMPHADENITIS ACUTA INGUINIS]
+∞
39.7
38
*
J01FF01
ATC
clindamycin; systemic
2.0
38.6
601
3439
J01DA01
ATC
[U] cefalexin; systemic
1.8
38.4
1374
10459
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
37.1
823
5348
K11.2
ICD-10 Finland
Sialoadenitis
5.1
36.7
121
250
H02AB06
ATC
prednisolone; systemic
1.8
36.5
967
6649
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
4.7
35.1
125
280
68308
ICD-8 Finland
Acute lymphadenitis, Alio loco definito
+∞
32.4
31
*
L04.8
ICD-10 Finland
Acute lymphadenitis of other sites
+∞
32.4
31
*
68301
ICD-8 Finland
Acute lymphadenitis, Axillae
+∞
31.3
30
*
I88.9
ICD-10 Finland
Nonspecific lymphadenitis, unspecified
15.8
31.3
51
33
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
30.1
305
1429
R50.9
ICD-10 Finland
Fever, unspecified
2.2
28.2
335
1688
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
27.6
537
3274
ENA32
NOMESCO Finland
Incision of deep pharyngeal infection
25.7
27.5
38
15
4701
FHL
Neck lymph node removal
25.7
27.5
38
15
Q18.0
ICD-10 Finland
Sinus, fistula and cyst of branchial cleft
13.4
26.5
46
35
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
25.4
808
5684
A02BC02
ATC
pantoprazole; systemic
1.6
23.8
1246
9899
J01MA02
ATC
ciprofloxacin; systemic
1.6
23.0
713
4949
M79.6
ICD-10 Finland
Pain in limb
1.6
23.0
705
4882
P01AB01
ATC
metronidazole; oral, rectal
1.6
22.7
784
5599
L04.1
ICD-10 Finland
Acute lymphadenitis of trunk
121.2
22.6
24
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
22.3
782
5598
J01MA12
ATC
levofloxacin; systemic
1.9
19.7
329
1877
R51.80
ICD-10 Finland
Headache
1.8
19.6
345
2007
N02BE01
ATC
paracetamol; systemic, rectal
1.6
19.4
1779
15719
N03AX16
ATC
pregabalin; oral
1.7
19.3
427
2673
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
18.5
533
3593
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
18.4
385
2364
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
18.3
430
2733
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
5.1
17.9
57
115
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
7.0
17.9
44
64
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.4
17.8
154
664
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
14.7
17.6
29
20
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
17.3
488
3260
A46
ICD-10 Finland
Erysipelas
2.0
17.0
220
1140
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
5.5
16.8
49
90
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
16.5
1108
8980
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
5.3
16.5
50
96
S18
ICPC
Laceration/cut
1.5
16.3
738
5511
AA1AD
NOMESCO Finland
CT of head and brain
1.7
16.2
372
2342
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
15.9
868
6732
R03AC02
ATC
salbutamol; inhalant
1.4
15.8
1082
8780
M04AA01
ATC
allopurinol; systemic
2.1
15.7
176
860
6839X
ICD-9 Finland
Acute lymphadenitis[LYMPHADENITIS ACUTA NUD]
+∞
15.6
15
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
15.6
473
3210
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
15.3
375
2404
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
15.1
875
6852
ENB40
NOMESCO Finland
Excision of branchial cyst or fistula
10.9
15.0
28
26
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
14.9
170
834
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
14.8
213
1149
UDC00
NOMESCO Finland
Ear microscopy
2.2
14.6
151
709
6831A
ICD-9 Finland
Acute lymphadenitis[LYMPHADENITIS ACUTA AXILLAE]
+∞
14.6
14
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.1
14.5
78
254
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
14.5
658
4892
R06.0
ICD-10 Finland
Dyspnoea
1.6
14.4
421
2826
J05AB01
ATC
aciclovir; systemic
1.6
14.4
408
2719
H02AB07
ATC
prednisone; oral
1.8
14.2
254
1479
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
14.2
487
3396
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
14.2
672
5038
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.8
14.1
60
163
A02BC05
ATC
esomeprazole; systemic
1.5
14.0
722
5502
J01AA02
ATC
doxycycline; systemic
1.4
13.8
1499
13104
A41.9
ICD-10 Finland
Sepsis, unspecified
3.6
13.6
61
173
M01AE02
ATC
naproxen; oral, rectal
1.4
13.6
1188
9967
R42
ICD-10 Finland
Dizziness and giddiness
1.6
13.6
362
2368
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.8
13.5
44
93
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
13.2
202
1112
N02AA05
ATC
oxycodone; systemic
1.9
13.1
210
1176
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
11.0
13.0
24
22
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
12.6
593
4417
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
2.1
12.5
152
766
XW000
NOMESCO Finland
Bone marrow biopsy
2.8
12.5
79
288
JN4BD
NOMESCO Finland
Extensive body CT
1.9
12.4
175
938
WX110
NOMESCO Finland
Local anesthesy
1.4
12.3
1470
12918
EMB10
NOMESCO Finland
Tonsillectomy
2.0
12.2
159
826
L05.9
ICD-10 Finland
Pilonidal cyst without abscess
37.7
12.2
15
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
12.1
322
2100
L03AA02
ATC
filgrastim; parenteral
3.3
12.1
59
180
P01BA02
ATC
hydroxychloroquine; oral
2.0
12.1
153
785
L05.0
ICD-10 Finland
Pilonidal cyst with abscess
26.8
12.0
16
6
UJF32
NOMESCO Finland
Coloscopy
1.5
11.9
407
2825
J05AB11
ATC
valaciclovir; oral
1.7
11.9
245
1490
A07AA02
ATC
nystatin; oral
2.3
11.9
110
492
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
11.8
96
404
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
4.6
11.7
39
85
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
11.4
110
504
D07AC01
ATC
betamethasone; topical
1.4
11.3
604
4596
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
11.1
425
3020
L28
ICPC
Limited function/disability (L)
1.7
11.1
229
1393
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
10.1
11.0
21
21
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
11.0
322
2152
J02AC01
ATC
fluconazole; systemic
1.4
11.0
752
5977
H02AB04
ATC
methylprednisolone; systemic
1.7
11.0
257
1621
S04
ICPC
Lump/swelling localized
1.8
11.0
187
1072
R06AE07
ATC
cetirizine; oral
1.4
10.9
898
7361
ZX120
NOMESCO Finland
Intravenous
1.9
10.8
163
894
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
10.8
344
2347
ZXA00
NOMESCO Finland
Right side
1.5
10.8
430
3084
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
4.7
10.7
35
75
E0000UV
ATC
NA
1.4
10.7
779
6253
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
6.6
10.5
26
40
R21
ICPC
Throat symptom/complaint
1.4
10.5
481
3550
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
10.4
319
2152
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.1
10.3
121
603
SPAT1263
SPAT
Sampling
1.4
10.2
841
6868
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.9
10.1
156
861
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
10.1
447
3268
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
10.1
476
3526
A03
ICPC
Fever
1.5
9.9
366
2576
L04
ICD-10 Finland
Acute lymphadenitis
12.2
9.8
17
14
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
9.8
157
882
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
9.7
54
183
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
9.7
125
648
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
7.4
9.7
22
30
J01DA06
ATC
[U] cefuroxime; systemic
1.6
9.7
273
1806
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.1
9.6
110
545
C82.1
ICD-10 Finland
Follicular lymphoma grade II
7.8
9.6
21
27
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.8
9.6
168
970
A04AA01
ATC
ondansetron; systemic, rectal
2.0
9.6
120
617
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
9.6
171
994
N03AX12
ATC
gabapentin; oral
1.6
9.5
249
1615
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
9.5
118
604
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
6.0
9.5
25
42
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
4.7
9.5
31
67
N05CF01
ATC
zopiclone; oral
1.4
9.5
494
3726
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.5
9.4
72
295
J01EA01
ATC
trimethoprim; systemic
1.4
9.3
416
3045
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.9
9.3
126
666
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.1
9.2
104
511
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.1
9.2
48
156
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
9.2
154
878
C81.0
ICD-10 Finland
Nodular lymphocyte predominant Hodgkin lymphoma
13.7
9.2
15
11
G44.2
ICD-10 Finland
Tension-type headache
1.6
9.2
248
1624
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.8
9.2
146
818
J36
ICD-10 Finland
Peritonsillar abscess
2.3
9.1
79
346
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.1
9.1
99
481
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.7
9.1
61
231
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
9.1
156
896
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.8
8.9
148
840
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
3.2
8.9
45
143
SPAT1153
SPAT
Removal of sutures
1.4
8.9
511
3919
C03CA01
ATC
furosemide; systemic
1.5
8.8
330
2328
M54.5
ICD-10 Finland
Low back pain
1.4
8.8
612
4843
X58
ICD-10 Finland
Exposure to other specified factors
1.6
8.8
263
1767
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.4
8.7
516
3978
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
8.6
175
1059
SPAT1260
SPAT
Consultation of another employee
1.5
8.6
315
2209
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
8.6
1477
13304
UKC02
NOMESCO Finland
Cystoscopy
1.6
8.5
218
1409
B02
ICPC
Lymph gland(s) enlarged/painful
3.8
8.4
34
91
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
8.4
200
1264
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
8.4
182
1124
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
8.3
464
3535
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.8
8.3
150
878
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.1
8.3
43
140
S10
ICPC
Boil/carbuncle
2.1
8.3
88
422
L01AA02
ATC
chlorambucil; oral
10.8
8.3
15
14
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
8.3
338
2426
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
8.2
107
558
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
8.1
273
1880
R55
ICD-10 Finland
Syncope and collapse
1.7
8.1
158
944
9663/3-C77.9
ICD-O-3
Hodgkin lymphoma, nodular sclerosis, NOS, of lymph node, NOS
33.5
8.1
10
*
A18.2
ICD-10 Finland
Tuberculous peripheral lymphadenopathy
33.5
8.1
10
*
A02BC01
ATC
omeprazole; systemic
1.4
8.1
444
3371
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
11.7
8.1
14
12
XQ800
NOMESCO Finland
Prick test
1.7
8.1
161
970
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
8.0
689
5617
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
22.1
8.0
11
5
ZXA05
NOMESCO Finland
Left side
1.4
8.0
382
2825
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
8.0
321
2295
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
5.3
8.0
23
44
A01AB09
ATC
miconazole; local oral
1.8
8.0
145
849
J01FA10
ATC
azithromycin; systemic
1.3
7.9
1247
11037
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
7.9
304
2154
WX002
NOMESCO Finland
Sedation and analgesia
1.5
7.9
298
2106
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
7.9
117
643
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
13.1
7.9
13
10
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.8
7.9
122
678
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
1.9
7.8
116
634
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
4.3
7.8
27
63
SPAT1310
SPAT
Counselling related to known health issue
1.3
7.8
601
4819
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
7.7
151
904
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.6
7.7
187
1192
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
7.7
139
814
N06AB04
ATC
citalopram; systemic
1.4
7.7
353
2592
E000001
ATC
NA
1.4
7.7
393
2943
K07.60
ICD-10 Finland
Snapping jaw
1.9
7.7
107
573
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.9
7.7
115
634
N05BA01
ATC
diazepam; systemic, rectal
1.6
7.6
209
1371
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
8.0
7.6
16
20
R53
ICD-10 Finland
Malaise and fatigue
1.4
7.6
349
2562
C81.7
ICD-10 Finland
Other classical Hodgkin lymphoma
11.9
7.6
13
11
TPJ00
NOMESCO Finland
Biopsy of superficial lymph node
11.9
7.6
13
11
A21.0
ICD-10 Finland
Ulceroglandular tularaemia
25.1
7.6
10
*
M79.1
ICD-10 Finland
Myalgia
1.5
7.6
232
1565
J35.0
ICD-10 Finland
Chronic tonsillitis
1.8
7.5
123
696
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
4.7
7.5
24
52
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
7.5
221
1479
WZC30
NOMESCO Finland
Teaching
1.6
7.4
204
1338
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
7.4
99
522
M03BX02
ATC
tizanidine; oral
1.3
7.4
1182
10439
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.4
7.4
34
102
J03.0
ICD-10 Finland
Streptococcal tonsillitis
2.1
7.4
82
403
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
7.4
497
3896
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
7.3
123
702
D07AB08
ATC
desonide; topical
1.6
7.3
186
1197
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.6
7.3
189
1222
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
7.3
299
2145
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
7.3
966
8327
6851A
ICD-9 Finland
Pilonidal cyst, Without mention of abscess
+∞
7.3
7
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.5
7.3
226
1527
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
4.9
7.3
22
45
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
2.6
7.2
50
194
R51.81
ICD-10 Finland
Facial pain NOS
2.8
7.2
43
155
SPAT1211
SPAT
Application of soft bandage
1.7
7.1
156
968
4703
FHL
Drainage of deep neck infection
20.1
7.1
10
5
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.8
7.1
127
742
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
7.1
244
1687
N06AA09
ATC
amitriptyline; systemic
1.7
7.1
140
841
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
12.1
7.1
12
10
R51
ICD-10 Finland
Headache
1.9
7.1
106
584
ELB30
NOMESCO Finland
Excision of submandibular gland
5.6
7.1
19
34
5702
FHL
Local lymph node removal (eg armpit, groin)
8.8
7.0
14
16
TAB00
NOMESCO Finland
Lumbar puncture
2.0
7.0
88
457
G47.3
ICD-10 Finland
Sleep apnoea
1.4
7.0
336
2488
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
7.0
622
5078
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.6
7.0
170
1083
L04AA01
ATC
[U] ciclosporin; systemic
3.5
7.0
30
86
QBA10
NOMESCO Finland
Incision of skin of trunk
5.5
6.9
19
35
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
6.9
194
1284
WW200
NOMESCO Finland
Immunization
2.4
6.9
55
232
L17
ICPC
Foot/toe symptom/complaint
1.4
6.9
412
3165
M25.5
ICD-10 Finland
Pain in joint
1.3
6.8
495
3921
C83.1
ICD-10 Finland
Mantle cell lymphoma
8.3
6.8
14
17
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.5
6.8
209
1414
A12AA04
ATC
calcium carbonate; oral
3.3
6.8
32
99
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
6.8
330
2446
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.6
6.7
171
1104
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.8
6.7
114
655
R74
ICPC
Upper respiratory infection acute
1.3
6.7
621
5099
F41.00
ICD-10 Finland
Moderate panic disorder
2.8
6.6
39
140
H53.1
ICD-10 Finland
Subjective visual disturbances
1.8
6.6
100
553
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.6
819
6982
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.7
6.6
137
837
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
6.6
142
880
D70.82
ICD-10 Finland
Drug-induced neutropenia
3.3
6.5
30
91
G50.1
ICD-10 Finland
Atypical facial pain
2.8
6.5
38
135
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
6.5
218
1504
J39.0
ICD-10 Finland
Retropharyngeal and parapharyngeal abscess
6.2
6.5
16
26
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
2.9
6.4
35
120
M10.9
ICD-10 Finland
Gout, unspecified
2.0
6.4
75
379
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
7.4
6.4
14
19
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
6.4
91
495
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
6.3
87
468
Q18.8
ICD-10 Finland
Other specified congenital malformations of face and neck
8.2
6.3
13
16
EP1BG
NOMESCO Finland
MRI examination of soft tissue of neck with high intesity magnet
8.2
6.3
13
16
N05BA04
ATC
oxazepam; oral
1.4
6.3
403
3126
L03.3
ICD-10 Finland
Cellulitis of trunk
9.3
6.3
12
13
L08
ICPC
Shoulder symptom/complaint
1.4
6.3
288
2110
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
2.8
6.3
37
133
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
6.3
411
3202
Z92.3
ICD-10 Finland
Personal history of irradiation
+∞
6.3
6
*
R04.2
ICD-10 Finland
Haemoptysis
2.5
6.3
46
189
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.9
6.2
88
478
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
4.3
6.2
21
49
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.1
6.2
67
329
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.2
1478
13554
N06AX16
ATC
venlafaxine; oral
1.4
6.2
251
1798
D07AA02
ATC
hydrocortisone; topical
1.4
6.2
267
1934
J45.1
ICD-10 Finland
Nonallergic asthma
1.7
6.2
120
721
R13
ICD-10 Finland
Dysphagia
1.8
6.2
93
516
L03.2
ICD-10 Finland
Cellulitis of face
5.7
6.1
16
28
A04
ICPC
Weakness/tiredness general
1.5
6.1
221
1545
SPAT1262
SPAT
Handing over of treatment supplies
1.4
6.1
262
1899
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
6.1
201
1380
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.1
6.1
63
302
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
6.1
142
896
N06AX11
ATC
mirtazapine; oral
1.3
6.1
530
4302
S63.5
ICD-10 Finland
Sprain and strain of wrist
2.0
6.1
68
339
R02
ICPC
Shortness of breath/dyspnoea
1.5
6.1
183
1230
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
3.3
6.1
28
86
L02.0
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of face
3.3
6.1
28
86
L04AX01
ATC
azathioprine; systemic
1.9
6.0
82
437
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.5
6.0
210
1457

Mortality – FinRegistry

Association

Association between endpoint L12_LYMPHADENITIS and mortality.

Females

Parameter HR [95% CI] p-value
L12_LYMPHADENITIS 1.573 [1.39, 1.78] < 0.001
Birth year 1.0 [0.99, 1.01] 0.956

During the follow-up period (1.1.1998 — 31.12.2019), 671 out of 8609 females with L12_LYMPHADENITIS died.

Males

Parameter HR [95% CI] p-value
L12_LYMPHADENITIS 1.915 [1.68, 2.19] < 0.001
Birth year 0.982 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 847 out of 9296 males with L12_LYMPHADENITIS died.

Mortality risk

Mortality risk for people of age

years, who have L12_LYMPHADENITIS.

N-year risk Females Males
1 0.179% 0.322%
5 1.175% 1.864%
10 2.562% 4.926%
15 5.328% 9.104%
20 9.277% 15.178%

Relationships between endpoints

Index endpoint: L12_LYMPHADENITIS – Acute lymphadenitis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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