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Hypertrophic disorders of skin

L12_HYPERTROPHICSKIN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L91
  • Cause of death: ICD-10 L91

2 out of 7 registries used, show all original rules.

2190

4. Check minimum number of events

None

2190

5. Include endpoints

2360

6. Filter based on genotype QC (FinnGen only)

2360

Control definitions (FinnGen only)

Control exclude
L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L80-L99
Name in latin
Morbositates hypertrophicae cutis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 2360 1740 620
Unadjusted period prevalence (%) 0.51 0.59 0.27
Median age at first event (years) 39.59 37.33 45.92

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2123
Matched controls
21232
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L91.0
ICD-10 Finland
Hypertrophic scar
6269.4
323.0
1810
23
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
562.2
160.1
157
*
TQW99
NOMESCO Finland
Other minor procedure on skin
9.5
118.1
256
303
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
112.5
117.4
127
12
70130
ICD-8 Finland
Other hypertrophic and atrophic conditions of the skin, Keloid scar
+∞
113.6
108
*
L91.8
ICD-10 Finland
Other hypertrophic disorders of skin
146.3
105.2
111
8
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
38.6
105.0
134
37
L91.9
ICD-10 Finland
Hypertrophic disorder of skin, unspecified
1025.5
101.0
98
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.2
78.6
263
561
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.9
75.9
267
601
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.7
72.5
269
639
7014B
ICD-9 Finland
Other hypertrophic and atrophic conditions of skin, Keloid scar[CICATRIX HYPERTROPHICA]
+∞
58.6
56
*
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
17.8
56.3
89
52
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
39.9
272
1035
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
18.4
39.4
61
34
S18
ICPC
Laceration/cut
1.9
36.9
822
5386
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
8.8
36.2
79
93
SPAT1153
SPAT
Removal of sutures
1.9
32.9
619
3783
ZZR00
NOMESCO Finland
Flap of skin
8.4
31.8
71
87
L90.6
ICD-10 Finland
Striae atrophicae
167.5
31.8
33
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
31.5
794
5342
DAB00
NOMESCO Finland
Excision of lesion of auricle
15.0
30.1
50
34
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
24.5
29.2
41
17
ZZA00
NOMESCO Finland
Split skin graft
6.4
29.1
78
126
QDE20
NOMESCO Finland
Excision and repair of scar or web of skin of lower limb
44.4
28.7
35
8
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
3.9
28.5
123
332
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
27.4
551
3406
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.2
26.5
84
167
J01FF01
ATC
clindamycin; systemic
1.8
26.1
548
3428
J01DB01
ATC
cefalexin; oral
1.8
26.1
1715
14878
N02BE01
ATC
paracetamol; systemic, rectal
1.8
25.8
1739
15164
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
12.0
25.7
47
40
QCE20
NOMESCO Finland
Excision and repair of scar or web of skin of upper limb
44.9
25.5
31
7
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.8
25.4
169
628
-
ICD-10 Finland
NA
5.5
25.3
76
142
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
25.3
268
1281
ZXA00
NOMESCO Finland
Right side
1.8
25.2
477
2876
D07AD01
ATC
clobetasol; topical
2.1
25.0
303
1540
N62
ICD-10 Finland
Hypertrophy of breast
3.3
24.9
129
404
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
3.6
23.7
110
316
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
6.4
23.7
63
101
QAE30
NOMESCO Finland
Excision and repair of surgical scar in head or neck
126.4
23.6
25
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
23.5
720
5017
ZXC12
NOMESCO Finland
Pulse colorlaser
19.7
23.5
35
18
9734
FHL
Excision and local plastic or associated free skin grafting
11.9
23.0
42
36
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
4.5
23.0
82
186
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
15.7
22.8
37
24
R4120
NOMESCO Finland
Occupational therapy
2.9
22.6
147
539
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
22.1
677
4698
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
22.0
768
5513
J01DA01
ATC
[U] cefalexin; systemic
1.6
21.9
1267
10306
ZXE00
NOMESCO Finland
One hour or less
1.6
21.7
808
5892
TQX05
NOMESCO Finland
Skin puncture, unspecified location
22.4
21.7
31
14
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
21.5
426
2595
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
6.0
21.4
59
100
ZXD05
NOMESCO Finland
Urgent procedure
1.7
21.3
630
4320
ZXC50
NOMESCO Finland
Cryotherapy
5.2
21.3
67
133
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.0
20.9
127
446
Z42.2
ICD-10 Finland
Follow-up care involving plastic surgery of other parts of trunk
77.6
20.7
23
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
20.6
730
5243
ZZF00
NOMESCO Finland
Graft of adipose tissue
7.7
20.4
47
62
QBA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of trunk
48.5
20.2
24
5
XQ848
NOMESCO Finland
Dermatological photography
4.5
19.8
71
162
L82
ICD-10 Finland
Seborrhoeic keratosis
2.1
19.6
235
1183
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.4
19.5
96
291
L57.0
ICD-10 Finland
Actinic keratosis
2.8
19.3
130
487
E0000UV
ATC
NA
1.6
19.3
796
5907
L91
ICD-10 Finland
Hypertrophic disorders of skin
191.6
18.6
19
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.9
18.5
288
1603
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.6
18.4
142
575
WX110
NOMESCO Finland
Local anesthesy
1.5
18.3
1433
12227
L70.0
ICD-10 Finland
Acne vulgaris
3.1
18.2
103
343
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
19.5
18.2
27
14
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
5.0
18.1
58
118
N03AX12
ATC
gabapentin; oral
1.9
17.9
291
1648
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
5.2
17.9
55
107
J01MA02
ATC
ciprofloxacin; systemic
1.6
17.9
660
4747
ZXA05
NOMESCO Finland
Left side
1.7
17.6
420
2688
N03AX16
ATC
pregabalin; oral
1.7
17.3
418
2684
M54.5
ICD-10 Finland
Low back pain
1.6
17.3
649
4679
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
21.1
17.3
25
12
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.5
17.2
51
95
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
17.2
522
3566
N06AX11
ATC
mirtazapine; oral
1.6
17.1
607
4315
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
17.1
489
3292
Z3226
NOMESCO Finland
Physiotherapist
1.8
16.8
342
2086
UJF32
NOMESCO Finland
Coloscopy
1.7
16.7
413
2667
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
16.3
339
2080
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
16.2
610
4389
QBA50
NOMESCO Finland
Cryotherapy of skin of trunk
21.1
16.0
23
11
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
15.9
410
2679
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
15.8
656
4820
QDE30
NOMESCO Finland
Excision and repair of surgical scar in lower limb
+∞
15.6
15
*
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
15.6
352
2209
J01EA01
ATC
trimethoprim; systemic
1.6
15.3
501
3474
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
8.4
15.2
33
40
ZQX00
NOMESCO Finland
0-4% of the skin
28.8
15.2
20
7
L89
ICD-10 Finland
Decubitus ulcer and pressure area
28.8
15.2
20
7
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
14.9
243
1371
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
14.9
250
1426
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
14.9
534
3783
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
14.9
406
2684
M79.6
ICD-10 Finland
Pain in limb
1.5
14.9
664
4943
A02BC02
ATC
pantoprazole; systemic
1.4
14.6
1158
9666
SPAT1301
SPAT
No procedures
1.5
14.6
601
4391
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
10.1
14.4
28
28
A02BC05
ATC
esomeprazole; systemic
1.5
14.4
719
5473
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.3
14.4
73
228
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.9
14.3
212
1155
N05AH04
ATC
quetiapine; oral
1.7
14.3
344
2195
P01AB01
ATC
metronidazole; oral, rectal
1.5
14.3
752
5786
D07AC01
ATC
betamethasone; topical
1.5
14.0
588
4310
ZXD20
NOMESCO Finland
Day surgery
1.8
13.7
256
1513
J01FA06
ATC
roxithromycin; oral
1.5
13.7
737
5681
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.3
13.7
127
568
J02AC01
ATC
fluconazole; systemic
1.4
13.7
840
6647
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
13.6
699
5336
Z3231
NOMESCO Finland
Registered nurse
1.5
13.6
489
3459
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
13.5
134
619
TQW80
NOMESCO Finland
Local dermatologic skincare
3.8
13.5
57
154
M25.5
ICD-10 Finland
Pain in joint
1.5
13.4
534
3858
N02AA05
ATC
oxycodone; systemic
1.9
13.4
201
1102
Z42.0
ICD-10 Finland
Follow-up care involving plastic surgery of head and neck
25.9
13.4
18
7
TQB05
NOMESCO Finland
Puncture of skin of trunk
5.6
13.3
38
69
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
4.2
13.3
50
122
9733
FHL
Excision of skin change in operating room or anesthesia
5.1
13.2
41
82
ZXA10
NOMESCO Finland
Bilateral
1.7
12.9
320
2059
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.7
12.9
86
324
Z2221
NOMESCO Finland
Medical doctor
1.5
12.8
540
3946
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
12.8
206
1160
S97
ICPC
Chronic ulcer skin
2.9
12.8
76
266
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
8.5
12.8
27
32
R51.80
ICD-10 Finland
Headache
1.6
12.7
327
2121
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
12.6
842
6732
XQ845
NOMESCO Finland
Dermatoscopy
6.1
12.4
33
55
R06AE07
ATC
cetirizine; oral
1.4
12.4
892
7225
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
12.3
155
796
WX002
NOMESCO Finland
Sedation and analgesia
1.6
12.3
321
2093
AA1AD
NOMESCO Finland
CT of head and brain
1.6
12.2
343
2277
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
12.2
193
1077
C03CA01
ATC
furosemide; systemic
1.6
12.1
334
2210
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
12.0
330
2176
SPAT1263
SPAT
Sampling
1.4
12.0
824
6612
J01MA12
ATC
levofloxacin; systemic
1.7
11.9
283
1795
A02BC03
ATC
lansoprazole; oral
1.5
11.9
474
3412
D10BA01
ATC
isotretinoin; oral
1.9
11.9
172
931
QBJ30
NOMESCO Finland
Correction of abdominal apron
5.7
11.8
33
59
N05CF02
ATC
zolpidem; oral
1.6
11.6
323
2135
E66.01
ICD-10 Finland
Obesity due to excess calories
1.9
11.6
171
931
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
11.5
167
903
R4110
NOMESCO Finland
Physiotherapy
1.5
11.4
430
3058
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
6.4
11.4
29
46
X58
ICD-10 Finland
Exposure to other specified factors
1.7
11.3
258
1617
ZQZ00
NOMESCO Finland
Treatment of several skin areas
15.1
11.3
18
12
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
11.3
961
7973
B01AB05
ATC
enoxaparin; parenteral
1.5
11.2
474
3452
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
11.1
1010
8459
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
11.1
482
3530
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
11.1
465
3380
HAD99
NOMESCO Finland
Other plastic operation on breast
7.1
11.0
26
37
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
5.6
11.0
31
56
C07AB07
ATC
bisoprolol; oral
1.4
11.0
647
5022
ZXC10
NOMESCO Finland
Use of laser
3.6
11.0
49
140
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
3.9
11.0
44
115
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
10.9
797
6427
TQA05
NOMESCO Finland
Puncture of skin of head or neck
43.5
10.9
13
*
Z00.0
ICD-10 Finland
General medical examination
1.6
10.9
347
2372
WX402
NOMESCO Finland
General anaesthesia
1.6
10.9
308
2046
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
10.8
284
1846
DAW99
NOMESCO Finland
Other operation on auricle
28.2
10.7
14
5
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.8
10.7
183
1052
S29
ICPC
Skin symptom/complaint other
1.6
10.6
294
1939
QCE30
NOMESCO Finland
Excision and repair of surgical scar in upper limb
60.3
10.6
12
*
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
2.1
10.6
125
624
TQW40
NOMESCO Finland
Remowal of suture of skin
2.1
10.6
123
613
N06AB06
ATC
sertraline; oral
1.7
10.5
230
1424
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
10.5
195
1149
SFA00
NOMESCO Finland
Small filling
1.7
10.5
241
1514
A46
ICD-10 Finland
Erysipelas
1.8
10.5
184
1064
L17
ICPC
Foot/toe symptom/complaint
1.5
10.4
431
3122
N06AB04
ATC
citalopram; systemic
1.5
10.4
388
2746
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
8.2
10.3
22
27
N05CF01
ATC
zopiclone; oral
1.4
10.3
511
3835
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
3.8
10.3
42
112
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.5
10.3
77
312
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
10.2
648
5085
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
10.2
394
2808
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
10.1
234
1472
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
10.0
498
3735
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.9
10.0
147
800
A01
ICPC
Pain general/multiple sites
2.0
10.0
129
669
N06AX16
ATC
venlafaxine; oral
1.6
10.0
284
1884
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
10.0
268
1756
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
10.0
89
393
R42
ICD-10 Finland
Dizziness and giddiness
1.5
9.9
331
2282
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
9.9
361
2538
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.6
9.9
270
1777
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
7.0
9.8
23
33
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.3
9.8
48
149
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
9.7
631
4965
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.5
9.6
359
2535
R53
ICD-10 Finland
Malaise and fatigue
1.5
9.6
364
2583
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.6
380
2720
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
9.6
136
733
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
9.5
122
633
SPAT1310
SPAT
Counselling related to known health issue
1.4
9.5
587
4576
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.6
9.4
232
1485
QBE25
NOMESCO Finland
Excision and repair of scar of trunk caused by burn
+∞
9.4
9
*
QDE35
NOMESCO Finland
Repair of skin defect in lower limb after surgery or injury
10.7
9.3
17
16
R03AC02
ATC
salbutamol; inhalant
1.3
9.2
1007
8587
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
9.2
449
3348
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
1.9
9.2
127
677
H02AB06
ATC
prednisolone; systemic
1.3
9.2
788
6474
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.1
9.2
101
491
WZA90
NOMESCO Finland
Other doctors statement
1.4
9.2
446
3326
N06AX21
ATC
duloxetine; oral
1.7
9.2
201
1247
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
9.1
171
1012
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
9.1
142
791
G44.2
ICD-10 Finland
Tension-type headache
1.6
9.1
263
1750
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.8
9.1
155
891
J01AA02
ATC
doxycycline; systemic
1.3
9.1
1422
12782
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
9.0
461
3468
L03
ICPC
Low back symptom/complaint
1.4
9.0
438
3262
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
9.0
98
476
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.4
9.0
72
303
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.1
9.0
98
478
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
8.9
796
6571
D10AF01
ATC
clindamycin; topical
2.0
8.9
112
577
J01AA07
ATC
tetracycline; systemic
1.5
8.8
314
2194
R05
ICD-10 Finland
Cough
1.5
8.8
329
2322
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.1
8.8
96
466
E000001
ATC
NA
1.5
8.8
382
2786
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
5.4
8.7
25
47
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
8.7
86
398
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
8.7
1347
12036
R52.2
ICD-10 Finland
Other chronic pain
2.5
8.7
64
258
ZXC07
NOMESCO Finland
Carbon dioxide laser
50.2
8.7
10
*
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
8.7
1837
17286
SPAT1260
SPAT
Consultation of another employee
1.5
8.6
306
2135
M01AH01
ATC
celecoxib; oral (coxibs)
1.5
8.6
271
1844
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
8.6
210
1342
DHB00
NOMESCO Finland
Excision of lesion of external nose
6.2
8.6
22
36
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.7
8.5
190
1185
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
8.4
138
781
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
5.4
8.4
24
45
QAE50
NOMESCO Finland
Dermabrasion of superficial lesion of skin of head or neck
90.4
8.4
9
*
ZZS45
NOMESCO Finland
Z-plasty
90.4
8.4
9
*
WX702
NOMESCO Finland
Supraglottic ventilation device
2.0
8.3
100
507
T95.1
ICD-10 Finland
Sequelae of burn, corrosion and frostbite of trunk
+∞
8.3
8
*
QBA00
NOMESCO Finland
Puncture of skin of trunk
8.6
8.3
17
20
J01CF02
ATC
cloxacillin; systemic
3.1
8.3
44
146
R50.9
ICD-10 Finland
Fever, unspecified
1.6
8.3
241
1608
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
8.3
1052
9110
S21
ICPC
Skin texture symptom/complaint
1.6
8.3
206
1320
XQ800
NOMESCO Finland
Prick test
1.7
8.2
157
933
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
14.5
8.2
13
9
C10AA01
ATC
simvastatin; oral
1.4
8.2
493
3813
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
7.6
8.2
18
24
K07.60
ICD-10 Finland
Snapping jaw
1.9
8.1
115
621
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
8.1
186
1170
D01
ICPC
Abdominal pain/cramps general
1.6
8.1
209
1356
N05BA04
ATC
oxazepam; oral
1.4
8.0
422
3187
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
8.0
307
2177
QBD20
NOMESCO Finland
Excision of burn of trunk and coverage
22.1
8.0
11
5
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
22.1
8.0
11
5
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
8.0
493
3823
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.4
8.0
36
106
T88.8
ICD-10 Finland
Other specified complications of surgical and medical care, not elsewhere classified
7.3
8.0
18
25
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.0
7.9
99
510
SDA02
NOMESCO Finland
Parodonthologic therapy
1.3
7.9
613
4930
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
7.9
1435
13018
M03BX02
ATC
tizanidine; oral
1.3
7.9
1148
10099
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.2
7.8
73
334
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
7.0
7.8
18
26
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
3.6
7.8
33
93
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
7.7
232
1560
Z42.9
ICD-10 Finland
Follow-up care involving plastic surgery, unspecified
45.1
7.7
9
*
G47.3
ICD-10 Finland
Sleep apnoea
1.5
7.7
299
2126
R01AD09
ATC
mometasone; nasal
1.3
7.7
878
7463
K59.09
ICD-10 Finland
Constipation, unspecified
2.1
7.7
86
424
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.0
7.7
93
475
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
7.6
147
878
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
3.0
7.6
41
138
A02BC01
ATC
omeprazole; systemic
1.4
7.6
437
3346
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
7.6
143
850
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.7
7.6
153
927
J01FA10
ATC
azithromycin; systemic
1.3
7.6
1182
10471
M01AE02
ATC
naproxen; oral, rectal
1.3
7.6
1101
9667
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
7.5
737
6130
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.5
7.5
57
235
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
2.6
7.5
50
193
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.8
7.4
44
157
QB001
NOMESCO Finland
Local radiotherapy of skin of trunk
80.4
7.4
8
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
7.4
124
710
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.6
7.4
51
199
L04AA01
ATC
[U] ciclosporin; systemic
3.8
7.3
29
77
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.2
7.3
74
349
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.3
7.3
25
58
BAA60
NOMESCO Finland
Total thyroidectomy
2.6
7.3
51
200
SPAT1211
SPAT
Application of soft bandage
1.7
7.3
149
908
QDA10
NOMESCO Finland
Incision of skin of lower limb
6.8
7.3
17
25
M01AB05
ATC
diclofenac; systemic, rectal
1.3
7.3
1187
10552
L84
ICD-10 Finland
Corns and callosities
2.8
7.3
44
160
F45.8
ICD-10 Finland
Other somatoform disorders
1.7
7.2
161
1003
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.7
7.2
136
807
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
7.2
164
1030
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
7.1
318
2327
127
Kela drug reimbursment
Transplant complication
3.8
7.1
28
75
L12
ICPC
Hand/finger symptom/complaint
1.5
7.0
247
1720
A06AD11
ATC
lactulose; oral
1.6
7.0
178
1146
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
7.0
72
343
104
Kela drug reimbursment
Thyroid insufficiency
1.8
7.0
115
654
K30
ICD-10 Finland
Functional dyspepsia
1.6
7.0
175
1125
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.2
7.0
69
321
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.0
7.0
88
457
AN1
HP
Coronary angiography
1.8
7.0
120
692
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
7.0
345
2569
J01CA04
ATC
amoxicillin; systemic
1.3
7.0
1659
15470
F51.0
ICD-10 Finland
Nonorganic insomnia
1.5
7.0
257
1807
HAD40
NOMESCO Finland
Mastopexy
6.3
6.9
17
27
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
6.9
180
1167
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
6.9
233
1608
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
2.1
6.9
76
373
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
6.9
204
1366
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
3.2
6.9
33
103
R04.0
ICD-10 Finland
Epistaxis
1.9
6.9
91
481
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
6.9
161
1018
Z71.8
ICD-10 Finland
Other specified counselling
1.4
6.8
448
3501
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
6.8
176
1139
M01AC06
ATC
meloxicam; systemic, rectal
1.3
6.8
580
4717
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
6.8
157
988
R52.9
ICD-10 Finland
Pain, unspecified
1.7
6.8
137
830
D11
ICPC
Diarrhoea
1.5
6.8
224
1539
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
6.8
127
755
T90.1
ICD-10 Finland
Sequelae of open wound of head
40.2
6.8
8
*
B07.9
ICD-10 Finland
Verruca simplex
2.1
6.7
70
336
A03FA02
ATC
cisapride; oral, rectal
1.8
6.7
111
635
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.1
6.7
68
324
QBG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of trunk
22.6
6.7
9
*
7014A
ICD-9 Finland
Other hypertrophic and atrophic conditions of skin, Keloid scar[CICATRIX KELOIDES]
22.6
6.7
9
*
ZZR10
NOMESCO Finland
Flap of skin and muscle
4.9
6.7
20
41
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
6.7
356
2689
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.6
242
1700
M01AX17
ATC
nimesulide; oral
1.4
6.6
339
2542
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
7.8
6.6
14
18
QBJ00
NOMESCO Finland
Liposuction in trunk
5.5
6.6
18
33
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
6.6
1061
9364
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
3.0
6.6
35
118
G50.1
ICD-10 Finland
Atypical facial pain
2.9
6.6
36
124
205
Kela drug reimbursment
Chronic hypertension
1.4
6.6
294
2148
N06AB10
ATC
escitalopram; oral
1.4
6.6
402
3104
XF402
NOMESCO Finland
ECG with work load test
1.7
6.6
140
863
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
6.5
275
1985
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
6.5
554
4500
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
2.3
6.5
58
259
E66.8
ICD-10 Finland
Other obesity
1.8
6.5
99
549
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
6.5
178
1171
J05AB11
ATC
valaciclovir; oral
1.5
6.5
219
1515
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.8
6.5
103
583
WF099
NOMESCO Finland
Other radiotherapy
5.7
6.4
17
30
R01AD08
ATC
fluticasone; nasal
1.3
6.4
512
4115
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
6.4
155
989
Z2446
NOMESCO Finland
Social worker
1.7
6.4
119
706
NGW99
NOMESCO Finland
Other reoperation in surgery of knee or lower leg
70.0
6.4
7
*
-1
NOMESCO Finland
NA
1.3
6.4
678
5674
N05BA01
ATC
diazepam; systemic, rectal
1.5
6.4
201
1366
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
6.4
142
888
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
3.1
6.4
32
104
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
6.4
211
1452
H02AB04
ATC
methylprednisolone; systemic
1.5
6.4
222
1542
D07CC01
ATC
betamethasone and antibiotics; topical
1.5
6.3
209
1437
R10.0
ICD-10 Finland
Acute abdomen
2.3
6.3
54
236
S99
ICPC
Skin disease other
3.0
6.3
34
116
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.6
6.3
166
1082
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.1
6.3
32
105
K59.1
ICD-10 Finland
Functional diarrhoea
2.0
6.3
80
417
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.9
6.3
92
505
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.8
6.3
103
586
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.4
6.3
48
200
J01FA01
ATC
erythromycin; systemic
1.4
6.3
278
2029
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.7
6.3
124
750
Z50.1
ICD-10 Finland
Other physical therapy
1.9
6.3
82
434
D07AC13
ATC
mometasone; topical
1.3
6.2
465
3700
WX704
NOMESCO Finland
Intubation
1.7
6.2
117
698
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.8
6.2
108
628
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
6.2
227
1593
C09CA06
ATC
candesartan; oral
1.4
6.2
310
2314
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
2.6
6.2
42
165
N06AB03
ATC
fluoxetine; oral
1.5
6.2
214
1485
T84.1
ICD-10 Finland
Mechanical complication of internal fixation device of bones of limb
6.3
6.2
15
24
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
2.1
6.1
64
310
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.1
914
7967
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.5
6.1
215
1498
M54.6
ICD-10 Finland
Pain in thoracic spine
1.7
6.1
116
693
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.1
516
4180
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
6.1
477
3820
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
6.1
510
4127
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
6.1
137
857
N45
ICD-10 Finland
Orchitis and epididymitis
12.5
6.1
10
8
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.6
6.1
134
837
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.9
6.0
84
454

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: L12_HYPERTROPHICSKIN – Hypertrophic disorders of skin

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).