Hidradenitis suppurativa

L12_HIDRADENITISSUP

hidradenitis suppurativa: a common (though rarely diagnosed), chronic skin disease characterized by clusters of abscesses or subcutaneous boil-like "infections" (oftentimes free of actual bacteria) that most commonly affects apocrine sweat gland bearing areas, such as the underarms, under the breasts, inner thighs, groin and buttocks.The disease is not contagious. There are indications that it is hereditary among certain ethnic groups and autoimmune in nature. Onset is most common in the late teens and early 20's.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L73.2
  • Hospital discharge: ICD-9 7058C
  • Cause of death: ICD-10 L73.2
  • Cause of death: ICD-9 7058C

2 out of 7 registries used, show all original rules.

1420

4. Check minimum number of events

None

1420

5. Include endpoints

None

1420

6. Filter based on genotype QC (FinnGen only)

1420

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L73
Name in latin
Hidradenitis suppurativa

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7919 4721 3160
Only index persons 7639 4620 3019
Unadjusted period prevalence (%)
Whole population 0.12 0.14 0.09
Only index persons 0.15 0.17 0.12
Median age at first event (years)
Whole population 38.04 36.15 40.86
Only index persons 37.79 36.01 40.52

-FinnGen-

Key figures

All Female Male
Number of individuals 1420 974 446
Unadjusted period prevalence (%) 0.29 0.33 0.20
Median age at first event (years) 40.37 37.88 45.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1262
Matched controls
12621
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L73.2
ICD-10 Finland
Hidradenitis suppurativa
10474.8
323.0
1205
13
S10
ICPC
Boil/carbuncle
18.6
234.5
381
286
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
25.5
230.8
333
175
J01FF01
ATC
clindamycin; systemic
7.5
228.2
748
2058
J01AA04
ATC
lymecycline; systemic
7.3
174.7
501
1043
J01AA07
ATC
tetracycline; systemic
6.4
162.6
523
1250
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
11.1
135.7
275
308
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
18.8
134.5
213
135
QBE05
NOMESCO Finland
Excision of sweat glands or sweat gland bearing skin from trunk
+∞
117.6
111
*
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
19.9
115.4
178
103
L72.1
ICD-10 Finland
Trichilemmal cyst
14.0
114.4
204
171
D10BA01
ATC
isotretinoin; oral
7.7
111.8
285
461
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
12.6
106.2
199
185
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
12.4
104.8
198
187
SPAT1148
SPAT
Treatment of chronic ulcer or burn
6.5
98.8
285
541
J01DB01
ATC
cefalexin; oral
7.4
96.7
1194
8888
7058C
ICD-9 Finland
Disorders of sweat glands, Other specified disorders of sweat glands[HIDRADENITIS SUPPURATIVA]
+∞
93.9
89
*
J04BA02
ATC
dapsone; oral
80.8
80.3
90
12
L70.0
ICD-10 Finland
Acne vulgaris
16.5
77.3
127
85
A10BA02
ATC
metformin; oral
3.7
75.4
399
1387
L02.8
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of other sites
19.1
75.4
117
67
380
Kela drug reimbursment
Adalimumab (hidradenitis suppurativa)
+∞
74.7
71
*
P01AB01
ATC
metronidazole; oral, rectal
3.0
73.4
677
3517
J04AB02
ATC
rifampicin; systemic
35.3
71.0
92
28
S18
ICPC
Laceration/cut
3.0
70.5
603
2954
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
7.0
70.1
186
306
J01DA01
ATC
[U] cefalexin; systemic
3.0
69.1
939
6166
D05BB02
ATC
acitretin; oral
15.5
63.3
106
74
QBA10
NOMESCO Finland
Incision of skin of trunk
27.3
59.4
82
32
L05.9
ICD-10 Finland
Pilonidal cyst without abscess
16.6
57.7
94
61
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.6
54.5
286
953
S97
ICPC
Chronic ulcer skin
8.3
54.4
126
167
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
8.0
52.7
125
172
103
Kela drug reimbursment
Diabetes, insulin-treated
3.1
51.6
340
1334
E0000UV
ATC
NA
2.5
51.5
610
3419
N02AX02
ATC
tramadol; systemic, rectal
2.5
50.6
561
3022
T90
ICPC
Diabetes non-insulin dependent
3.3
50.3
293
1051
SPAT1146
SPAT
Puncture of abscess or incision of skin
14.6
50.2
86
63
E66.01
ICD-10 Finland
Obesity due to excess calories
4.0
49.6
219
626
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.1
49.4
330
1303
N07BA03
ATC
varenicline; oral
5.2
47.7
159
342
N02BE01
ATC
paracetamol; systemic, rectal
3.2
46.5
1119
8971
L05.0
ICD-10 Finland
Pilonidal cyst with abscess
22.8
46.2
67
31
SPAT1149
SPAT
Suture or treatment of traumatic wound
3.8
45.3
216
657
J01DA09
ATC
[U] cefadroxil; inhalant, oral
2.5
44.9
464
2367
L04AB04
ATC
adalimumab; parenteral
8.5
42.3
95
119
TQW80
NOMESCO Finland
Local dermatologic skincare
10.3
41.2
83
86
L73.8
ICD-10 Finland
Other specified follicular disorders
34.5
41.0
53
16
J01CF05
ATC
flucloxacillin; systemic
6.6
39.9
107
175
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.6
39.2
193
598
XQ848
NOMESCO Finland
Dermatological photography
10.0
39.2
80
85
J01MA02
ATC
ciprofloxacin; systemic
2.3
39.0
492
2730
SPAT1262
SPAT
Handing over of treatment supplies
3.0
37.2
252
980
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
37.2
494
2794
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
3.2
36.4
211
738
H02AB06
ATC
prednisolone; systemic
2.1
35.8
606
3801
N05AH04
ATC
quetiapine; oral
2.6
35.1
303
1362
ZZR00
NOMESCO Finland
Flap of skin
13.2
35.1
62
49
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.0
34.5
225
853
K61.0
ICD-10 Finland
Anal abscess
9.5
33.9
71
79
L02.0
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of face
11.2
33.5
64
60
T82
ICPC
Obesity
5.3
32.7
104
210
J01MA12
ATC
levofloxacin; systemic
2.8
32.0
240
989
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
3.1
31.5
193
698
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.9
31.2
136
377
L70.1
ICD-10 Finland
Acne conglobata
87.4
30.9
34
*
J01AA02
ATC
doxycycline; systemic
2.2
30.9
977
7728
E66.8
ICD-10 Finland
Other obesity
3.9
30.8
136
382
SPAT1263
SPAT
Sampling
2.0
30.2
590
3833
N02AJ06
ATC
codeine and paracetamol; systemic
2.0
29.8
520
3226
S04
ICPC
Lump/swelling localized
3.2
29.6
166
563
TQW99
NOMESCO Finland
Other minor procedure on skin
6.1
29.1
82
143
SPAT1260
SPAT
Consultation of another employee
2.5
29.1
259
1173
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
8.4
29.1
65
81
S29
ICPC
Skin symptom/complaint other
2.6
28.9
231
984
S92
ICPC
Sweat gland disease
298.5
28.9
29
*
D07AD01
ATC
clobetasol; topical
2.6
28.3
225
956
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
4.2
28.1
112
286
A02BC02
ATC
pantoprazole; systemic
1.9
28.0
774
5674
K60.3
ICD-10 Finland
Anal fistula
8.6
27.8
61
74
C03CA01
ATC
furosemide; systemic
2.6
27.2
219
936
D07AC01
ATC
betamethasone; topical
2.0
27.1
436
2589
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.6
27.1
97
223
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.4
27.0
278
1352
S76
ICPC
Skin infection other
4.5
26.9
99
234
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
26.6
714
5130
C07AB07
ATC
bisoprolol; oral
2.0
25.9
432
2595
G47.3
ICD-10 Finland
Sleep apnoea
2.3
25.8
287
1444
E000001
ATC
NA
2.2
25.8
309
1614
R03AC02
ATC
salbutamol; inhalant
1.9
25.8
701
5035
N06AB04
ATC
citalopram; systemic
2.2
25.6
310
1624
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
4.3
25.5
98
242
WX110
NOMESCO Finland
Local anesthesy
2.0
25.4
939
7512
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
25.3
564
3765
N06AX11
ATC
mirtazapine; oral
2.0
25.2
427
2570
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
6.0
25.2
71
124
N03AX16
ATC
pregabalin; oral
2.2
25.2
297
1537
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
25.0
500
3205
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.4
24.9
250
1198
E66.00
ICD-10 Finland
Metabolic syndrome
4.1
24.8
102
268
L73.9
ICD-10 Finland
Follicular disorder, unspecified
49.4
24.4
29
6
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
24.2
593
4073
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.3
24.0
130
428
M79.6
ICD-10 Finland
Pain in limb
1.9
23.9
445
2768
L70.8
ICD-10 Finland
Other acne
31.7
23.8
31
10
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
23.7
128
421
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.5
23.5
85
198
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.5
22.6
194
850
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.3
22.6
241
1182
N61
ICD-10 Finland
Inflammatory disorders of breast
4.7
22.5
79
178
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
22.5
341
1950
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
22.4
528
3547
WX002
NOMESCO Finland
Sedation and analgesia
2.3
22.3
227
1088
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.6
22.2
104
306
N76.4
ICD-10 Finland
Abscess of vulva
12.1
22.1
40
34
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
22.0
231
1124
A46
ICD-10 Finland
Erysipelas
2.7
21.9
164
666
9733
FHL
Excision of skin change in operating room or anesthesia
9.9
21.9
44
46
D10AF01
ATC
clindamycin; topical
3.3
21.9
115
370
J02AC01
ATC
fluconazole; systemic
1.8
21.9
582
4060
J01DB05
ATC
cefadroxil; oral
4.1
21.9
87
222
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.3
21.8
226
1093
J01FA01
ATC
erythromycin; systemic
2.2
21.7
250
1268
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
21.6
428
2699
N03AX12
ATC
gabapentin; oral
2.4
21.6
199
908
A10AE04
ATC
insulin glargine; parenteral
3.0
21.5
131
466
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
12.6
21.4
38
31
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
21.3
366
2187
J01XC01
ATC
fusidic acid; systemic
10.1
21.2
42
43
JHA00
NOMESCO Finland
Anal or perianal incision
8.0
21.2
48
62
L72.9
ICD-10 Finland
Follicular cyst of skin and subcutaneous tissue, unspecified
24.7
20.9
29
12
TQW11
NOMESCO Finland
Vacuum treatment of wound
8.2
20.6
46
58
EBA00
NOMESCO Finland
Extraction of tooth
1.8
20.6
452
2940
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
20.5
408
2564
N02AA05
ATC
oxycodone; systemic
2.8
20.5
139
532
E66.9
ICD-10 Finland
Obesity, unspecified
4.2
20.5
79
196
N06AX16
ATC
venlafaxine; oral
2.2
20.4
233
1173
N05BA04
ATC
oxazepam; oral
2.0
20.4
329
1917
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.8
20.3
139
535
Z3231
NOMESCO Finland
Registered nurse
2.0
20.3
330
1926
SPAT1301
SPAT
No procedures
1.9
20.1
377
2319
N05CF01
ATC
zopiclone; oral
1.9
20.1
346
2061
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.0
20.1
286
1583
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.4
19.9
74
177
WX290
NOMESCO Finland
Other blockade of nerve
1.7
19.8
672
5000
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
19.7
490
3310
A06AD11
ATC
lactulose; oral
2.8
19.7
137
530
A10BK03
ATC
empagliflozin; oral
3.4
19.6
97
298
QBG99
NOMESCO Finland
Other operation for chronic ulcer or fistula of skin
203.0
19.6
20
*
9734
FHL
Excision and local plastic or associated free skin grafting
22.0
19.5
28
13
UJF32
NOMESCO Finland
Coloscopy
2.0
19.3
270
1480
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.7
19.3
734
5633
M54.5
ICD-10 Finland
Low back pain
1.8
19.3
447
2948
D07XC01
ATC
betamethasone, combinations; topical
2.6
19.2
154
650
K05.31
ICD-10 Finland
Periodontitis pronounced
2.8
19.0
126
473
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
9.8
18.9
38
40
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.5
18.5
161
709
A10BH01
ATC
sitagliptin; oral
3.1
18.4
105
358
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.9
18.3
316
1877
L72.0
ICD-10 Finland
Epidermal cyst
22.1
18.2
26
12
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
7.4
18.1
43
60
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.5
18.1
154
671
M01AE03
ATC
ketoprofen; systemic, rectal
1.8
18.1
429
2835
D95
ICPC
Anal fissure/perianal abscess
10.9
18.0
34
32
SPAT1153
SPAT
Removal of sutures
1.9
17.9
339
2078
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
16.8
17.9
28
17
SPAT1240
SPAT
Therapeutic discussion
2.2
17.9
200
997
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
17.8
168
771
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
17.8
303
1788
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.9
17.8
111
402
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
17.8
345
2132
SPAT1310
SPAT
Counselling related to known health issue
1.8
17.6
404
2637
A10BJ06
ATC
semaglutide; parenteral
4.6
17.5
61
137
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.9
17.5
74
200
A02BC03
ATC
lansoprazole; oral
1.9
17.4
308
1840
N05BA01
ATC
diazepam; systemic, rectal
2.4
17.2
163
746
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
4.7
17.2
59
131
P76
ICPC
Depressive disorder
2.7
17.1
123
486
D07AC13
ATC
mometasone; topical
1.8
17.1
356
2249
L88
ICD-10 Finland
Pyoderma gangrenosum
50.7
17.0
20
*
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
5.8
16.9
48
86
G03HB01
ATC
cyproterone and estrogen; systemic
2.2
16.9
195
983
R02
ICPC
Shortness of breath/dyspnoea
2.4
16.9
148
653
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
16.8
937
7870
QBG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of trunk
64.2
16.8
19
*
J01FA06
ATC
roxithromycin; oral
1.7
16.6
488
3415
E66
ICD-10 Finland
Obesity
3.2
16.6
91
303
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.8
16.6
370
2384
N05AX08
ATC
risperidone; systemic
2.8
16.4
108
405
L17
ICPC
Foot/toe symptom/complaint
1.9
16.4
287
1703
L03
ICPC
Low back symptom/complaint
1.8
16.4
312
1906
N06AB10
ATC
escitalopram; oral
1.8
16.3
312
1911
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.2
16.3
189
954
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.9
16.3
45
78
N06AB03
ATC
fluoxetine; oral
2.2
16.2
182
903
D07AB08
ATC
desonide; topical
2.3
16.2
155
715
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
16.1
649
4949
SPAT1211
SPAT
Application of soft bandage
2.6
16.0
121
493
H02AB07
ATC
prednisone; oral
2.2
15.8
168
814
ZY010
NOMESCO Finland
Hospital outpatient
2.9
15.8
99
358
N06AX12
ATC
bupropion; oral
2.5
15.8
127
534
9731
FHL
Opening and channeling of the inflammatory site in the operating room or anesthesia
33.8
15.8
20
6
P17
ICPC
Tobacco abuse
5.8
15.7
44
78
N06AX21
ATC
duloxetine; oral
2.3
15.6
153
712
ZZA00
NOMESCO Finland
Split skin graft
5.4
15.5
46
87
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.9
15.5
262
1530
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.1
15.5
88
300
K02.1
ICD-10 Finland
Caries of dentine
1.6
15.4
779
6276
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
5.7
15.4
44
80
D07CC01
ATC
betamethasone and antibiotics; topical
2.2
15.2
171
850
P99
ICPC
Psychological disorders other
3.9
15.1
63
169
B01AB05
ATC
enoxaparin; parenteral
1.8
15.0
301
1866
L03.3
ICD-10 Finland
Cellulitis of trunk
12.6
14.9
26
21
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
14.9
210
1145
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
4.5
14.9
53
123
L28
ICPC
Limited function/disability (L)
2.4
14.8
136
614
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
4.7
14.8
50
110
L71.9
ICD-10 Finland
Rosacea, unspecified
8.8
14.8
31
36
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.2
14.7
154
739
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.6
14.7
108
431
N06AB06
ATC
sertraline; oral
2.1
14.7
174
886
Z72.0
ICD-10 Finland
Tobacco use
4.2
14.7
55
134
R05
ICPC
Cough
1.8
14.6
276
1672
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
14.6
237
1364
A10BB12
ATC
glimepiride; oral
4.0
14.5
58
150
68599
ICD-8 Finland
Pilonidal cyst
12.7
14.4
25
20
WZC30
NOMESCO Finland
Teaching
2.2
14.3
154
750
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
2.1
14.3
173
886
QDA10
NOMESCO Finland
Incision of skin of lower limb
10.6
14.3
27
26
SGA01
NOMESCO Finland
Tooth opening as first aid
1.9
14.2
235
1360
R03BB04
ATC
tiotropium bromide; inhalant
2.8
14.2
92
343
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.1
14.2
166
840
R06.0
ICD-10 Finland
Dyspnoea
1.9
14.1
248
1467
D11
ICPC
Diarrhoea
2.1
14.1
178
930
A28
ICPC
Limited function/disability NOS
2.6
14.0
108
445
M54.4
ICD-10 Finland
Lumbago with sciatica
1.9
13.9
217
1231
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
13.7
175
916
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.7
13.6
93
358
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.7
13.5
59
165
S01
ICPC
Pain/tenderness of skin
3.4
13.5
65
197
C07AA05
ATC
propranolol; systemic
1.8
13.5
262
1598
F32.1
ICD-10 Finland
Moderate depressive episode
2.5
13.5
106
442
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
13.5
300
1909
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
2.1
13.5
159
805
9752
FHL
Surgical treatment of hyperhidrosis
141.5
13.5
14
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.1
13.4
152
756
SPAT1254
SPAT
Administration of medicine
2.1
13.4
165
853
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
13.4
220
1269
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
5.4
13.2
39
74
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.3
13.2
122
552
C03DA01
ATC
spironolactone; oral
2.6
13.1
94
372
SPAT1283
SPAT
Restricted health certificate
1.7
13.1
325
2139
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
9.5
13.0
26
28
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.2
12.9
140
684
160
Kela drug reimbursment
exenatide
5.7
12.7
36
65
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
12.7
387
2692
205
Kela drug reimbursment
Chronic hypertension
2.0
12.6
182
998
D05AX52
ATC
calcipotriol, combinations; topical
2.8
12.6
79
289
L03.9
ICD-10 Finland
Cellulitis, unspecified
5.6
12.6
36
66
M25.5
ICD-10 Finland
Pain in joint
1.7
12.5
348
2358
70591
ICD-8 Finland
Diseases of sweat glands, Hidrosadenitis
+∞
12.5
12
*
ZXE00
NOMESCO Finland
One hour or less
1.6
12.5
478
3521
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
12.5
186
1032
M01AE02
ATC
naproxen; oral, rectal
1.5
12.4
705
5697
R06AE07
ATC
cetirizine; oral
1.5
12.3
559
4283
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
12.3
222
1320
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
12.2
209
1219
M01AE01
ATC
ibuprofen; systemic, rectal
2.0
12.2
1151
10597
R96
ICPC
Asthma
2.4
12.2
109
487
H03AA01
ATC
levothyroxine sodium; systemic
1.7
12.2
266
1679
N05AH02
ATC
clozapine; systemic
4.1
12.2
46
114
C10AA01
ATC
simvastatin; oral
1.7
12.1
285
1841
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.2
12.1
120
563
UKC02
NOMESCO Finland
Cystoscopy
2.2
12.0
127
612
L02
ICPC
Back symptom/complaint
2.2
12.0
132
649
R50.9
ICD-10 Finland
Fever, unspecified
2.0
12.0
164
879
6851A
ICD-9 Finland
Pilonidal cyst, Without mention of abscess
10.2
12.0
23
23
A10BX07
ATC
[U] liraglutide; parenteral
9.4
12.0
24
26
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.6
12.0
54
156
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.5
11.9
96
406
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
6.5
11.9
30
47
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.5
11.9
93
388
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
6.2
11.9
31
51
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.6
11.8
88
355
N05AA02
ATC
levomepromazine; systemic
3.2
11.8
61
196
L71.8
ICD-10 Finland
Other rosacea
14.8
11.8
19
13
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
11.8
134
667
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.2
11.8
44
108
SPAT1151
SPAT
Treatment of major wounds
9.0
11.8
24
27
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
11.7
220
1325
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
11.7
148
770
M01AH05
ATC
etoricoxib; oral
1.5
11.6
697
5662
WX320
NOMESCO Finland
Spinalanesthesy
1.8
11.6
236
1454
J01DA06
ATC
[U] cefuroxime; systemic
1.9
11.6
181
1021
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.3
11.5
42
101
Z2446
NOMESCO Finland
Social worker
2.5
11.5
93
395
J01CE02
ATC
phenoxymethylpenicillin; oral
1.6
11.4
902
7785
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.6
11.4
322
2185
J01CF02
ATC
cloxacillin; systemic
4.8
11.4
37
79
R95
ICPC
Chron obstructive pulmonary disease
5.6
11.4
32
58
L16
ICPC
Ankle symptom/complaint
2.1
11.4
127
629
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
11.4
413
2988
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.3
11.3
56
175
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.2
11.3
42
103
A10BJ02
ATC
liraglutide; parenteral
4.5
11.3
39
89
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.9
11.2
66
232
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.5
11.2
88
368
S06
ICPC
Rash localized
2.8
11.1
70
257
L70.9
ICD-10 Finland
Acne, unspecified
8.7
11.0
23
27
N05CD07
ATC
temazepam; oral
2.3
11.0
103
469
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
4.3
11.0
40
96
N05AH03
ATC
olanzapine; systemic
2.3
11.0
98
437
N06AX03
ATC
mianserin; oral
3.1
11.0
62
210
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.3
10.9
101
459
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.6
10.9
305
2059
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.0
10.9
136
704
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
10.8
681
5550
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.1
10.8
130
664
N03AG01
ATC
valproic acid; systemic, rectal
2.4
10.8
91
393
SPAT1058
SPAT
PEF monitoring instruction
2.4
10.8
94
415
K50.8
ICD-10 Finland
Other Crohn disease
4.6
10.7
36
80
L04AX01
ATC
azathioprine; systemic
2.8
10.7
70
261
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
7.6
10.7
24
32
K04.1
ICD-10 Finland
Necrosis of pulp
2.0
10.6
144
768
I50.9
ICD-10 Finland
Heart failure, unspecified
2.8
10.6
70
263
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
4.3
10.6
38
90
A02BC01
ATC
omeprazole; systemic
1.6
10.6
282
1876
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.5
10.6
469
3541
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
10.5
164
923
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
10.5
155
857
S99
ICPC
Skin disease other
5.1
10.5
32
64
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
10.5
158
880
Z00.0
ICD-10 Finland
General medical examination
1.8
10.5
209
1280
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.5
10.4
81
337
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
3.5
10.4
48
142
L75.9
ICD-10 Finland
Apocrine sweat disorder, unspecified
+∞
10.4
10
*
D01AC02
ATC
miconazole; topical
2.4
10.4
84
357
L02.1
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of neck
7.8
10.4
23
30
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.9
10.3
150
825
H60.0
ICD-10 Finland
Abscess of external ear
8.3
10.3
22
27
ZXA05
NOMESCO Finland
Left side
1.7
10.3
228
1437
D10AX03
ATC
azelaic acid; topical
2.0
10.3
126
648
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.3
10.3
96
437
WX402
NOMESCO Finland
General anaesthesia
1.8
10.3
203
1238
M03BX02
ATC
tizanidine; oral
1.5
10.3
754
6315
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
9.7
10.3
20
21
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.5
10.2
79
328
J20
ICD-10 Finland
Acute bronchitis
2.1
10.2
114
563
N05AN01
ATC
lithium; oral
3.4
10.2
48
145
-1
NOMESCO Finland
NA
1.5
10.2
456
3444
M01AB05
ATC
diclofenac; systemic, rectal
1.5
10.1
772
6508
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
10.1
427
3177
S21
ICPC
Skin texture symptom/complaint
2.0
10.1
133
704
D07BC01
ATC
betamethasone and antiseptics; topical
2.0
10.1
135
719
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
10.1
112
553
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
10.1
237
1522
Z71.8
ICD-10 Finland
Other specified counselling
1.6
10.1
301
2063
L12
ICPC
Hand/finger symptom/complaint
1.9
10.1
164
939
N06AA09
ATC
amitriptyline; systemic
2.3
10.1
97
449
P03
ICPC
Feeling depressed
1.9
10.1
153
854
L30.3
ICD-10 Finland
Infective dermatitis
3.4
10.0
48
147
L68.0
ICD-10 Finland
Hirsutism
14.7
10.0
16
11
P29
ICPC
Psychological sympt/compl other
2.2
10.0
101
476
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
10.0
382
2777
J01MA14
ATC
moxifloxacin; systemic
2.2
10.0
97
452
P72
ICPC
Schizophrenia
4.0
10.0
38
96
K04.08
ICD-10 Finland
Other specified pulpit
2.1
9.9
110
542
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
9.9
99
467
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
9.9
96
446
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
9.9
110
544
C08CA01
ATC
amlodipine; oral
1.6
9.9
255
1679
S19
ICPC
Skin injury other
3.3
9.8
48
149
162
Kela drug reimbursment
liraglutide
8.2
9.8
21
26
N05AX12
ATC
aripiprazole; systemic
2.6
9.8
73
296
SPAT1312
SPAT
General health counselling
1.5
9.8
390
2858
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
9.8
303
2091
ZXD05
NOMESCO Finland
Urgent procedure
1.5
9.8
381
2783
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.1
9.7
117
595
R60.0
ICD-10 Finland
Localized oedema
2.2
9.7
97
456
E66.0
ICD-10 Finland
Obesity due to excess calories
7.4
9.7
22
30
R06.5
ICD-10 Finland
Mouth breathing
2.1
9.7
107
528
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.3
9.7
87
390
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
9.7
231
1487
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
3.8
9.7
39
104
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.3
9.6
47
146
SPAT1229
SPAT
Assessment of need for aid
2.7
9.6
64
242
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
2.2
9.6
99
474
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
9.6
144
802
R51.80
ICD-10 Finland
Headache
1.7
9.5
194
1194
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
9.5
621
5050
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
9.4
302
2100
6850A
ICD-9 Finland
Pilonidal cyst, With abscess
17.7
9.4
14
8
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
9.3
106
529
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
9.3
119
624
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
9.3
99
481
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.5
9.2
70
288
A02BA02
ATC
ranitidine; systemic
1.8
9.2
172
1029
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
9.2
264
1785
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
9.2
88
405
L84
ICD-10 Finland
Corns and callosities
3.3
9.2
45
141
RD210
NOMESCO Finland
NA
3.9
9.2
36
94
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
3.9
9.2
36
94
ZXA10
NOMESCO Finland
Bilateral
1.8
9.2
173
1038
A10AE05
ATC
insulin detemir; parenteral
2.6
9.1
65
257
M79.1
ICD-10 Finland
Myalgia
1.8
9.1
156
907
SPA47
NOMESCO Finland
Precision impression for denture
5.9
9.1
24
41
2780A
ICD-9 Finland
Obesity and other hyperalimentation, Obesity
15.7
9.0
14
9
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
7.1
9.0
21
30
N07BB01
ATC
disulfiram; oral
2.5
9.0
71
297
TQW40
NOMESCO Finland
Remowal of suture of skin
2.3
9.0
80
357
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.7
9.0
214
1375
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.9
9.0
139
782
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.3
9.0
85
392
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.3
8.9
43
133
L08
ICPC
Shoulder symptom/complaint
1.7
8.9
192
1200
N49.9
ICD-10 Finland
Inflammatory disorder of unspecified male genital organ
24.2
8.9
12
5
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.4
8.9
42
128
A99
ICPC
Disease/condition unspecnature/site
2.3
8.9
84
386
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
3.6
8.9
38
107
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.5
8.9
30
68
J01FA09
ATC
clarithromycin; systemic
1.5
8.8
377
2799
C10AA05
ATC
atorvastatin; oral
1.6
8.8
265
1814
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.8
8.8
151
878
E000003
ATC
NA
2.6
8.7
63
253
K04.0
ICD-10 Finland
Pulpitis
1.8
8.7
147
849
K50.9
ICD-10 Finland
Crohn disease, unspecified
4.1
8.7
32
79
T89
ICPC
Diabetes insulin dependent
2.7
8.6
59
229
N01
ICPC
Headache
1.8
8.6
159
948
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
8.6
132
737
C09AA05
ATC
ramipril; oral
1.7
8.6
170
1034
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
8.6
89
425
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
8.6
119
644
N06AX05
ATC
trazodone; oral
3.2
8.6
44
143
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.7
8.6
56
213
A03
ICPC
Fever
1.6
8.6
223
1467
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
8.5
105
543
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.0
8.5
46
155
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
8.5
354
2608
X58
ICD-10 Finland
Exposure to other specified factors
1.8
8.5
164
992
QBE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of trunk
20.2
8.5
12
6
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.4
8.5
68
289
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
4.4
8.5
29
67
H13
ICPC
Plugged feeling ear
1.8
8.4
150
882
M70.6
ICD-10 Finland
Trochanteric bursitis
2.0
8.4
110
582
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
8.4
184
1154
D10
ICPC
Vomiting
2.0
8.4
101
515
SPAT1255
SPAT
Intravenous administration of medicine
2.5
8.4
65
272
R05FB02
ATC
cough suppressants and expectorants
1.5
8.4
371
2766
L40.8
ICD-10 Finland
Other psoriasis
6.8
8.4
20
30
ZXA00
NOMESCO Finland
Right side
1.6
8.4
233
1562
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
8.3
142
824
A10BG03
ATC
pioglitazone; oral
4.5
8.3
28
64
G56.2
ICD-10 Finland
Lesion of ulnar nerve
3.0
8.2
45
153
R03AC03
ATC
terbutaline; inhalant
1.7
8.2
160
969
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
8.2
230
1543
L70.2
ICD-10 Finland
Acne varioliformis
14.6
8.2
13
9
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
8.2
726
6178
J01MA01
ATC
ofloxacin; systemic
2.2
8.1
82
390
L05
ICPC
Flank/axilla symptom/complaint
2.4
8.1
68
295
K10.3
ICD-10 Finland
Alveolitis of jaws
2.4
8.1
68
296
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
8.1
227
1526
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.5
8.0
62
258
B01AC04
ATC
clopidogrel; oral
2.0
8.0
95
484
56510
ICD-8 Finland
Anal fissure and fistula, Anal fistula
22.2
8.0
11
5
SPAT1216
SPAT
Assessment of functional ability
1.9
8.0
113
616
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.1
8.0
85
412
S80.0
ICD-10 Finland
Contusion of knee
2.1
8.0
83
401
J01FA10
ATC
azithromycin; systemic
1.4
7.9
742
6357
Z3226
NOMESCO Finland
Physiotherapist
1.7
7.9
186
1191
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.0
7.9
106
566
R51
ICD-10 Finland
Headache
2.2
7.9
75
346
C09AA02
ATC
enalapril; systemic
1.8
7.9
135
787
H01
ICPC
Ear pain/earache
1.8
7.8
145
864
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
3.5
7.8
35
103
V03AA01
ATC
NA
4.7
7.8
25
54
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.7
7.8
51
194
L11
ICPC
Wrist symptom/complaint
2.0
7.8
105
560
D07AA02
ATC
hydrocortisone; topical
1.7
7.8
169
1054
A02BC05
ATC
esomeprazole; systemic
1.4
7.8
410
3158
A10BD07
ATC
metformin and sitagliptin; systemic
2.9
7.8
45
158
R74
ICPC
Upper respiratory infection acute
1.4
7.8
411
3169
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
7.8
77
364
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.0
7.7
92
468
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.8
7.7
139
823
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.6
7.7
53
207
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
7.7
108
586
L08.0
ICD-10 Finland
Pyoderma
5.6
7.7
21
38
SPAT1008
SPAT
Photography of fundus of the eye or interpretation of photograph
3.0
7.7
42
144
J01CA04
ATC
amoxicillin; systemic
1.5
7.6
1013
9235
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
4.2
7.6
27
65
A07EC01
ATC
sulfasalazine; oral, rectal
2.0
7.6
94
488
S93
ICPC
Sebaceous cyst
8.1
7.6
16
20
N06AA06
ATC
trimipramine; systemic
3.6
7.6
32
90
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.7
7.6
50
192
QXB10
NOMESCO Finland
Exchange of dressing for large skin wound, unspecified location
25.2
7.6
10
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.7
7.6
49
186
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.9
7.5
103
554
KMAK
NOMESCO Finland
NA
1.4
7.5
676
5724
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
5.8
7.5
20
35
WX702
NOMESCO Finland
Supraglottic ventilation device
2.3
7.5
67
299
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
7.5
77
369
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
3.7
7.5
31
86
310
Kela drug reimbursment
Orlistat, sibutramine and other major and expensive medicines used to treat obesity
7.2
7.5
17
24
L15
ICPC
Knee symptom/complaint
1.6
7.5
195
1284
R03BA02
ATC
budesonide; inhalant
1.6
7.4
193
1267
J96.1
ICD-10 Finland
Chronic respiratory failure
5.3
7.4
21
40
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.0
7.4
98
522
N03AX09
ATC
lamotrigine; oral
2.1
7.4
77
373
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
4.0
7.4
28
72
L04AD01
ATC
ciclosporin; systemic
4.0
7.4
28
72
JHD20
NOMESCO Finland
Incision of fistula-in-ano
5.6
7.4
20
36
N05BA06
ATC
lorazepam; systemic, sublingual
2.6
7.4
52
208
B02AA02
ATC
tranexamic acid; systemic
1.6
7.4
186
1211
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
7.3
87
442
R52.2
ICD-10 Finland
Other chronic pain
2.9
7.3
42
146
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
4.8
7.3
23
49
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
7.3
236
1637
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
7.3
137
820
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
7.3
163
1029
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.9
7.2
106
583
ZYC01
NOMESCO Finland
Remote contact by phone
2.4
7.2
60
261
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.2
7.2
73
349
N05CF02
ATC
zolpidem; oral
1.6
7.2
192
1270
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
3.8
7.2
28
74
QWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of skin
20.1
7.1
10
5
M01AH02
ATC
rofecoxib; oral
1.9
7.1
109
609
D02AX
ATC
Other emollients and protectives
2.8
7.1
43
157
E000002
ATC
NA
1.7
7.1
145
889
XQ802
NOMESCO Finland
Epicutan test
2.4
7.1
56
236
F41.1
ICD-10 Finland
Generalized anxiety disorder
2.2
7.1
74
355
R05FA02
ATC
opium derivatives and expectorants; systemic
1.4
7.1
422
3313
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
3.6
7.1
30
85
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
7.1
101
550
M54.6
ICD-10 Finland
Pain in thoracic spine
2.0
7.1
85
434
SPAT1097
SPAT
Recording of ECG
1.8
7.1
118
683
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.7
7.1
45
168
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.3
7.0
64
290
H60.3
ICD-10 Finland
Other infective otitis externa
3.2
7.0
34
107
M03BC51
ATC
orphenadrine, combinations; systemic
1.5
7.0
320
2386
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.9
7.0
97
525
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
7.0
119
691
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
3.9
7.0
27
71
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
5.2
6.9
20
39
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.9
6.9
100
548
ZX112
NOMESCO Finland
Subcutaneous
4.3
6.9
24
57
D01
ICPC
Abdominal pain/cramps general
1.7
6.9
130
779
SPA50
NOMESCO Finland
Determination of bite and dental arch location
7.6
6.9
15
20
F20.9
ICD-10 Finland
Schizophrenia, unspecified
3.1
6.9
36
120
RD211
NOMESCO Finland
NA
2.5
6.9
49
197
C10AA07
ATC
rosuvastatin; oral
1.6
6.9
183
1209
R5599
NOMESCO Finland
Other rehabilitation service
3.2
6.9
34
109
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
2.7
6.9
44
165
E000006
ATC
NA
2.1
6.8
79
397
K50.0
ICD-10 Finland
Crohn disease of small intestine
3.5
6.8
30
88
A10BJ01
ATC
exenatide; parenteral
6.7
6.8
16
24
ACC51
NOMESCO Finland
Release of median nerve
2.0
6.8
83
426
R07
ICPC
Sneezing/nasal congestion
1.9
6.8
95
515
R03BA01
ATC
beclometasone; inhalant
1.7
6.8
147
920
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
5.3
6.8
19
36
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.0
6.8
85
444
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
40.3
6.8
8
*
9749
FHL
Other measure in this category
16.8
6.7
10
6
QXA05
NOMESCO Finland
Skin division, unspecified location
16.8
6.7
10
6
E0001A1
ATC
NA
2.9
6.7
37
128
Z2445
NOMESCO Finland
Psychologist
2.3
6.7
57
251
A07EC02
ATC
mesalazine; oral, rectal
2.1
6.7
76
379
H3600, E113
ICD-10 Finland
NA
7.2
6.7
15
21
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.2
6.7
62
285
R53
ICD-10 Finland
Malaise and fatigue
1.5
6.7
208
1426
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.6
6.7
47
187
IGY99
NOMESCO Finland
Other psychiatric treatment contact
3.2
6.7
33
106
F25.80
ICD-10 Finland
Other specified schizoaffective disorder with only concomitant bipolar and schizophrenic symptoms
22.6
6.7
9
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
6.7
107
608
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.7
6.7
131
794
L03.8
ICD-10 Finland
Cellulitis of other sites
7.9
6.6
14
18
O32.1
ICD-10 Finland
Maternal care for breech presentation
0.3
6.6
10
380
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
6.6
480
3895
L30.0
ICD-10 Finland
Nummular dermatitis
2.8
6.6
39
141
K04.7
ICD-10 Finland
Periapical abscess without sinus
2.1
6.6
69
336
S85
ICPC
Pilonidal cyst/fistula
12.3
6.6
11
9
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.1
6.6
34
113
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.1
6.5
71
351
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
0.7
6.5
195
2710
R11
ICD-10 Finland
Nausea and vomiting
2.0
6.5
83
435
ZX120
NOMESCO Finland
Intravenous
1.9
6.5
91
495
-50
ICPC
Medication/prescr/renewal
2.5
6.5
47
192
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.3
6.5
55
242
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.1
6.5
66
318
K04.00
ICD-10 Finland
Hyperemia of pulp
2.2
6.5
65
309
N05AB03
ATC
perphenazine; systemic, rectal
2.5
6.4
47
193
L72.2
ICD-10 Finland
Steatocystoma multiplex
70.2
6.4
7
*
R21
ICPC
Throat symptom/complaint
1.5
6.4
282
2084
K04.09
ICD-10 Finland
Pulpit UNS
2.2
6.4
58
265
ZXC07
NOMESCO Finland
Carbon dioxide laser
14.4
6.4
10
7
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
3.3
6.4
29
88
B01AA03
ATC
warfarin; systemic
1.8
6.4
96
538
N75.1
ICD-10 Finland
Abscess of Bartholin gland
4.4
6.4
21
48
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.8
6.3
38
139
F51.0
ICD-10 Finland
Nonorganic insomnia
1.6
6.3
167
1101
A08AB01
ATC
orlistat; oral
8.2
6.3
13
16
M01AC06
ATC
meloxicam; systemic, rectal
1.4
6.3
349
2693
WX400
NOMESCO Finland
Inhalation anesthesy
2.2
6.3
60
280
L14
ICPC
Leg/thigh symptom/complaint
2.0
6.3
73
369
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
6.3
113
669
G44.2
ICD-10 Finland
Tension-type headache
1.6
6.3
156
1011
L86
ICPC
Back syndrome with radiating pain
2.1
6.3
66
319
L20.0
ICD-10 Finland
Besnier prurigo
1.8
6.3
102
583
F32
ICD-10 Finland
Depressive episode
2.0
6.3
79
413
F10.20
ICD-10 Finland
Alcohol dependence currently independent
3.2
6.2
30
95
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.0
6.2
77
401
ZXD20
NOMESCO Finland
Day surgery
1.7
6.2
137
862
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
0.6
6.2
114
1749
A10BX04
ATC
[U] exenatide; parenteral
7.1
6.2
14
20
S20
ICPC
Corn/callosity
4.1
6.2
22
54
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.2
6.2
61
288
WZA90
NOMESCO Finland
Other doctors statement
1.5
6.2
269
1982
SPE01
NOMESCO Finland
Mucosa-supported partial denture
5.1
6.2
18
36
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
6.2
51
223
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
6.2
359
2796
K08.3
ICD-10 Finland
Retained dental root
2.1
6.2
68
338
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
6.2
219
1549
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.4
6.2
48
204
P74
ICPC
Anxiety disorder/anxiety state
2.2
6.2
61
290
M01AX17
ATC
nimesulide; oral
1.5
6.1
199
1377
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
7.7
6.1
13
17
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.0
6.1
32
108
M79.7
ICD-10 Finland
Fibromyalgia
2.4
6.1
47
198
N05BA12
ATC
alprazolam; oral
1.7
6.1
114
682
SPAT1252
SPAT
Overall medication plan or its review
2.2
6.1
56
259
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.4
6.1
20
46
F34.1
ICD-10 Finland
Dysthymia
2.3
6.0
50
220

Mortality – FinRegistry

Association

Association between endpoint L12_HIDRADENITISSUP and mortality.

Females

Parameter HR [95% CI] p-value
L12_HIDRADENITISSUP 2.542 [2.09, 3.09] < 0.001
Birth year 0.992 [0.98, 1.0] 0.08

During the follow-up period (1.1.1998 — 31.12.2019), 168 out of 3437 females with L12_HIDRADENITISSUP died.

Males

Parameter HR [95% CI] p-value
L12_HIDRADENITISSUP 2.558 [2.19, 2.99] < 0.001
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 286 out of 2336 males with L12_HIDRADENITISSUP died.

Mortality risk

Mortality risk for people of age

years, who have L12_HIDRADENITISSUP.

N-year risk Females Males
1 0.225% 0.52%
5 1.414% 2.929%
10 3.201% 7.481%
15 6.359% 14.047%
20 11.188% 22.631%

Relationships between endpoints

Index endpoint: L12_HIDRADENITISSUP – Hidradenitis suppurativa

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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