Tuberculosis, Cutaneous: Tuberculosis of the skin. It includes scrofuloderma and tuberculid, but not LUPUS VULGARIS.
Granulomatous disorders of skin and subcutaneous tissue
DOID EFO Endpoint Browser PheWeb
L12_GRANULOMATOUSSKIN
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
949 |
4. Check minimum number of eventsNone |
949 |
5. Include endpoints |
978 |
6. Filter based on genotype QC (FinnGen only) |
978 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L80-L99
- Name in latin
- Morbositates granulomatosae cutis et telae subcutaneae
Similar endpoints
↥List of similar endpoints to
Granulomatous disorders of skin and subcutaneous tissue
based on the number of shared cases.
Similar with more cases:
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6497 | 4475 | 1996 |
| Only index persons | 6066 | 4239 | 1827 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.13 | 0.06 |
| Only index persons | 0.13 | 0.16 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 48.67 | 49.20 | 47.60 |
| Only index persons | 48.68 | 49.22 | 47.42 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 978 | 733 | 245 |
| Unadjusted period prevalence (%) | 0.21 | 0.25 | 0.11 |
| Median age at first event (years) | 49.85 | 47.18 | 57.84 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 878
- Matched controls
- 8780
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L92.0
ICD-10 Finland
Granuloma annulare
2492.8
323.0
469
*
L92.1
ICD-10 Finland
Necrobiosis lipoidica, not elsewhere classified
2579.1
204.4
190
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
14.3
158.1
290
292
L92.3
ICD-10 Finland
Foreign body granuloma of skin and subcutaneous tissue
215.1
94.4
96
5
L92.9
ICD-10 Finland
Granulomatous disorder of skin and subcutaneous tissue, unspecified
+∞
70.8
67
*
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
13.7
60.8
108
89
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
9.4
60.5
131
160
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
11.5
60.4
117
116
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
6.7
55.9
153
267
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.9
54.3
268
886
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
18.5
53.7
84
50
L92.8
ICD-10 Finland
Other granulomatous disorders of skin and subcutaneous tissue
+∞
51.6
49
*
A10AE04
ATC
insulin glargine; parenteral
5.5
51.0
164
349
D07AC01
ATC
betamethasone; topical
3.1
50.4
403
1902
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
6.3
50.3
144
265
H04AA01
ATC
glucagon; nasal, parenteral
12.6
49.0
90
79
D07AD01
ATC
clobetasol; topical
3.9
46.3
223
709
A10AA01
ATC
NA
11.7
45.8
87
82
A10AA02
ATC
NA
10.6
44.7
89
92
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
9.2
43.9
95
114
A10AE05
ATC
insulin detemir; parenteral
6.7
43.6
117
196
T89
ICPC
Diabetes insulin dependent
8.4
42.7
98
130
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.2
41.8
271
1074
103
Kela drug reimbursment
Diabetes, insulin-treated
3.1
40.6
280
1155
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
12.0
39.6
74
67
A10AE06
ATC
insulin degludec; parenteral
8.6
32.4
72
90
XQ848
NOMESCO Finland
Dermatological photography
12.9
31.9
57
47
E0000UV
ATC
NA
2.4
31.4
417
2431
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
62.4
31.3
36
6
D07AC13
ATC
mometasone; topical
2.5
31.0
317
1608
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
14.1
30.3
52
39
SPAT1262
SPAT
Handing over of treatment supplies
3.0
29.7
201
797
TQW80
NOMESCO Finland
Local dermatologic skincare
10.3
29.1
58
60
H3603, E103
ICD-10 Finland
NA
20.5
29.0
43
22
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
25.7
26.8
37
15
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
23.3
26.7
38
17
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
35.3
26.7
34
10
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
13.1
25.6
45
36
H3600, E103
ICD-10 Finland
NA
14.9
24.1
40
28
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.7
23.3
188
817
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
20.7
23.1
34
17
E10
ICD-10 Finland
Type 1 diabetes mellitus
9.0
23.1
49
57
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
5.2
22.3
71
146
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
36.1
22.2
28
8
L92.2
ICD-10 Finland
Granuloma faciale [eosinophilic granuloma of skin]
+∞
22.0
21
*
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
8.5
20.9
46
57
CKC12
NOMESCO Finland
Photocoagulation of retina
5.2
20.6
65
132
H3601, E103
ICD-10 Finland
NA
14.7
20.5
34
24
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
8.1
20.0
45
58
E000001
ATC
NA
2.3
19.6
218
1111
J01FF01
ATC
clindamycin; systemic
2.1
19.1
267
1505
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
19.8
18.3
27
14
H36.00
ICD-10 Finland
Diabetic background retinopathy
10.7
17.8
34
33
7094A
ICD-9 Finland
Other disorders of skin and subcutaneous tissue, Foreign body granuloma of skin and subcutaneous tissue
+∞
17.8
17
*
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
14.9
17.7
29
20
J04BA02
ATC
dapsone; oral
37.5
17.7
22
6
J01DA01
ATC
[U] cefalexin; systemic
1.8
16.7
562
4304
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.1
16.6
53
110
L94.0
ICD-10 Finland
Localized scleroderma [morphea]
173.1
16.5
17
*
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
10.0
16.3
32
33
177
Kela drug reimbursment
Insulin glargine 300 U / ml
7.8
16.3
37
49
XCK10
NOMESCO Finland
Photography of fundus of eye
2.9
15.7
102
384
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
16.4
15.3
24
15
S97
ICPC
Chronic ulcer skin
4.7
15.2
52
116
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
8.4
14.4
31
38
J02AC01
ATC
fluconazole; systemic
1.8
14.3
398
2806
P01BA02
ATC
hydroxychloroquine; oral
2.8
13.8
91
344
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
13.5
237
1429
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.5
13.5
112
487
N03AX12
ATC
gabapentin; oral
2.2
13.4
145
718
171
Kela drug reimbursment
Degludekinsuliini
22.9
12.9
18
8
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.4
12.9
64
201
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
5.2
12.7
39
78
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.2
12.7
138
682
A10AA03
ATC
NA
11.2
12.6
23
21
H02AB06
ATC
prednisolone; systemic
1.7
12.3
394
2858
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
12.2
345
2410
D07AB02
ATC
hydrocortisone butyrate; topical
1.8
12.0
259
1661
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
5.7
12.0
34
62
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
11.7
168
936
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
7.3
11.6
27
38
A10AB06
ATC
insulin glulisine; parenteral
8.8
11.6
24
28
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.3
11.5
117
560
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.6
11.5
88
364
UJF32
NOMESCO Finland
Coloscopy
1.9
11.5
202
1210
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.4
11.5
102
457
H43.1
ICD-10 Finland
Vitreous haemorrhage
6.2
11.4
30
50
H36.01
ICD-10 Finland
Diabetic maculopathy
8.5
11.3
24
29
N02BE01
ATC
paracetamol; systemic, rectal
1.9
11.3
736
6459
CKC15
NOMESCO Finland
Panretinal photocoagulation
12.1
10.9
19
16
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
10.8
214
1331
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.5
10.8
31
58
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
10.7
10.8
20
19
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
5.1
10.7
33
67
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.8
10.7
208
1286
S29
ICPC
Skin symptom/complaint other
2.0
10.6
148
812
C10AA01
ATC
simvastatin; oral
1.7
10.5
295
2036
J01FA10
ATC
azithromycin; systemic
1.6
10.4
508
4050
S18
ICPC
Laceration/cut
1.6
10.4
329
2348
SPAT1263
SPAT
Sampling
1.6
10.2
372
2748
SPAT1153
SPAT
Removal of sutures
1.7
10.2
253
1683
M65.3
ICD-10 Finland
Trigger finger
3.2
10.1
53
174
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.8
10.0
41
111
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
10.0
188
1144
C03CA01
ATC
furosemide; systemic
1.8
9.9
183
1106
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.0
9.9
57
199
N03AX16
ATC
pregabalin; oral
1.8
9.9
195
1206
N02AX02
ATC
tramadol; systemic, rectal
1.6
9.9
328
2359
J01MA02
ATC
ciprofloxacin; systemic
1.6
9.7
304
2153
A10BK01
ATC
dapagliflozin; oral
3.4
9.4
45
139
7098B
ICD-9 Finland
Other disorders of skin and subcutaneous tissue, Other specified disorders of skin[NECROBIOSIS LIPOIDICA]
+∞
9.4
9
*
R06AE07
ATC
cetirizine; oral
1.6
9.4
379
2854
D86.3
ICD-10 Finland
Sarcoidosis of skin
22.0
9.4
13
6
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.7
9.4
62
236
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
10.8
9.3
17
16
D02AE01
ATC
carbamide; topical
2.6
9.1
68
279
Z94.0
ICD-10 Finland
Kidney transplant status
8.4
9.1
19
23
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
9.1
222
1461
V03AE01
ATC
polystyrene sulfonate; oral
11.6
9.1
16
14
XQ845
NOMESCO Finland
Dermatoscopy
9.2
9.1
18
20
A46
ICD-10 Finland
Erysipelas
2.1
9.0
100
496
XG410
NOMESCO Finland
Flow-volume spirometry
3.2
9.0
45
144
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
18.8
8.9
13
7
H3602, E103
ICD-10 Finland
NA
24.3
8.9
12
5
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
8.8
90
431
T90
ICPC
Diabetes non-insulin dependent
1.8
8.8
164
990
127
Kela drug reimbursment
Transplant complication
6.4
8.8
22
35
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.1
8.7
96
475
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
3.4
8.7
41
125
S06
ICPC
Rash localized
2.8
8.7
55
206
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
8.6
180
1130
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.9
8.6
27
57
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
16.5
8.6
13
8
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
16.5
8.6
13
8
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
8.5
228
1534
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
3.4
8.5
40
122
M25.5
ICD-10 Finland
Pain in joint
1.6
8.5
241
1652
J01AA02
ATC
doxycycline; systemic
1.6
8.4
653
5671
A10AD04
ATC
insulin lispro; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
12.9
8.4
14
11
A10BA02
ATC
metformin; oral
1.7
8.3
192
1237
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
10.9
8.3
15
14
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
5.2
8.2
24
47
D01AE15
ATC
terbinafine; topical
2.6
8.2
59
237
S99
ICPC
Skin disease other
5.8
8.2
22
39
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.3
8.1
78
362
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
8.1
289
2092
C07AB07
ATC
bisoprolol; oral
1.5
8.1
329
2460
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
22.2
8.0
11
5
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
22.2
8.0
11
5
E000003
ATC
NA
2.9
8.0
47
168
M54.5
ICD-10 Finland
Low back pain
1.6
8.0
274
1962
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
7.9
195
1283
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
6.2
7.9
20
33
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.6
7.8
16
19
L57.0
ICD-10 Finland
Actinic keratosis
2.4
7.8
64
278
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
7.8
88
444
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
7.8
144
870
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
7.7
132
773
N18.8
ICD-10 Finland
Other chronic renal failure
4.6
7.7
25
55
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
7.7
89
452
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
7.7
146
887
A02BC05
ATC
esomeprazole; systemic
1.5
7.5
322
2425
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.4
7.5
62
271
N06AX21
ATC
duloxetine; oral
2.0
7.5
98
524
H02AB09
ATC
hydrocortisone; systemic
4.5
7.5
25
57
L17
ICPC
Foot/toe symptom/complaint
1.6
7.5
197
1316
371
Kela drug reimbursment
Degludekinsuliini
80.7
7.4
8
*
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
80.7
7.4
8
*
L04AA06
ATC
mycophenolic acid; systemic
5.7
7.4
20
36
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.8
7.4
23
49
L43.8
ICD-10 Finland
Other lichen planus
4.8
7.4
23
49
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.8
7.4
23
49
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
7.3
148
920
L60.0
ICD-10 Finland
Ingrowing nail
2.8
7.2
43
156
L89
ICD-10 Finland
Decubitus ulcer and pressure area
15.9
7.2
11
7
L84
ICD-10 Finland
Corns and callosities
3.9
7.2
28
74
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
7.2
59
255
C10AA05
ATC
atorvastatin; oral
1.5
7.2
258
1860
A02BC02
ATC
pantoprazole; systemic
1.5
7.2
513
4287
L98.0
ICD-10 Finland
Pyogenic granuloma
30.3
7.2
9
*
ACC51
NOMESCO Finland
Release of median nerve
2.2
7.1
70
333
E000002
ATC
NA
1.9
7.1
104
577
N06AX05
ATC
trazodone; oral
3.7
7.1
29
80
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
5.4
7.1
20
38
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
7.1
193
1301
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.9
7.1
109
616
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
7.0
116
673
SPAT1255
SPAT
Intravenous administration of medicine
2.4
7.0
56
241
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
7.0
331
2535
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
7.0
429
3473
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.0
6.9
92
495
R01AD09
ATC
mometasone; nasal
1.5
6.9
384
3037
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
6.9
251
1816
D07AB08
ATC
desonide; topical
1.9
6.8
93
506
L91.0
ICD-10 Finland
Hypertrophic scar
11.0
6.8
12
11
J01DB01
ATC
cefalexin; oral
1.5
6.8
694
6222
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.8
299
2253
ZY010
NOMESCO Finland
Hospital outpatient
2.5
6.8
50
204
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.2
6.7
67
320
ZXA00
NOMESCO Finland
Right side
1.6
6.7
199
1365
M79.6
ICD-10 Finland
Pain in limb
1.5
6.7
280
2082
XW000
NOMESCO Finland
Bone marrow biopsy
3.1
6.7
34
112
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.5
6.7
48
196
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
6.7
62
288
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
6.7
246
1782
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
3.3
6.6
31
96
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
6.6
157
1017
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
6.6
310
2364
J05AB01
ATC
aciclovir; systemic
1.6
6.6
174
1160
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
2.5
6.6
47
191
N03AE01
ATC
clonazepam; systemic
2.4
6.6
53
230
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.2
6.5
32
103
J01CA04
ATC
amoxicillin; systemic
1.5
6.5
696
6261
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.6
6.5
95
1517
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
6.5
388
3107
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
6.4
97
545
J01CF05
ATC
flucloxacillin; systemic
3.1
6.4
33
110
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
6.4
363
2875
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
3.2
6.4
31
99
R03AC02
ATC
salbutamol; inhalant
1.4
6.3
432
3542
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
6.3
142
905
TNX30
NOMESCO Finland
Soft bandage, unspecified region
5.6
6.3
17
31
D02AX
ATC
Other emollients and protectives
2.9
6.3
36
126
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
11.1
6.3
11
10
G63.2
ICD-10 Finland
Diabetic polyneuropathy
11.1
6.3
11
10
QXA50
NOMESCO Finland
Skin cryotherapy, unspecified location
11.1
6.3
11
10
R51.80
ICD-10 Finland
Headache
1.7
6.3
125
771
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
6.3
98
560
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
18.2
6.3
9
5
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
+∞
6.3
6
*
A02BC01
ATC
omeprazole; systemic
1.5
6.2
214
1519
R4180
NOMESCO Finland
Podiatric therapy
7.1
6.2
14
20
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.3
6.2
53
235
R03BA01
ATC
beclometasone; inhalant
1.8
6.2
111
663
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
6.2
325
2527
CKD40
NOMESCO Finland
Endophotocoagulation of retina
4.5
6.2
20
45
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
6.2
84
458
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
6.1
62
297
R42
ICD-10 Finland
Dizziness and giddiness
1.6
6.1
162
1080
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
6.1
110
659
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
6.8
6.0
14
21
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.6
6.0
41
163
NH3CG
NOMESCO Finland
Extensive MRI of foot
10.1
6.0
11
11
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
10.1
6.0
11
11
R06AX22
ATC
ebastine; oral
1.6
6.0
147
960
H03AA01
ATC
levothyroxine sodium; systemic
1.6
6.0
192
1342
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.0
6.0
75
395
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.8
6.0
23
61
Mortality – FinRegistry
↥Association
Association between endpoint L12_GRANULOMATOUSSKIN and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_GRANULOMATOUSSKIN | 1.145 [1.0, 1.32] | 0.059 |
| Birth year | 0.999 [0.99, 1.01] | 0.746 |
During the follow-up period (1.1.1998 — 31.12.2019), 354 out of 3770 females with L12_GRANULOMATOUSSKIN died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_GRANULOMATOUSSKIN | 1.461 [1.22, 1.75] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 267 out of 1645 males with L12_GRANULOMATOUSSKIN died.
Mortality risk
Mortality risk for people of age
years, who have L12_GRANULOMATOUSSKIN.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.143% | 0.267% |
| 5 | 0.787% | 1.629% |
| 10 | 1.85% | 4.028% |
| 15 | 3.655% | 7.592% |
| 20 | 6.152% | 13.196% |
Relationships between endpoints
↥Index endpoint: L12_GRANULOMATOUSSKIN – Granulomatous disorders of skin and subcutaneous tissue
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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