No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
824 |
4. Check minimum number of eventsNone |
824 |
5. Include endpointsNone |
824 |
6. Filter based on genotype QC (FinnGen only) |
824 |
Control definitions (FinnGen only)
- Control exclude
- L12_DERMATITISECZEMA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L30
- Name in latin
- Intertrigo
Similar endpoints
↥List of similar endpoints to
Erythema intertrigo
based on the number of shared cases.
Similar with more cases:
- Dermatitis
- Dermatitis and eczema
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5579 | 2921 | 2627 |
| Only index persons | 4898 | 2577 | 2321 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | 0.07 |
| Only index persons | 0.09 | 0.09 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 62.82 | 66.01 | 59.27 |
| Only index persons | 62.54 | 65.75 | 58.99 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 824 | 440 | 384 |
| Unadjusted period prevalence (%) | 0.16 | 0.15 | 0.17 |
| Median age at first event (years) | 64.32 | 64.71 | 63.88 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 735
- Matched controls
- 7351
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L30.4
ICD-10 Finland
Erythema intertrigo
14215.7
323.0
723
14
L30.9
ICD-10 Finland
Dermatitis, unspecified
11.6
138.8
290
390
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
7.0
116.4
373
948
E0000UV
ATC
NA
5.2
93.8
442
1657
TQW80
NOMESCO Finland
Local dermatologic skincare
39.0
86.7
110
33
D07AC01
ATC
betamethasone; topical
4.2
69.2
363
1374
E000001
ATC
NA
4.3
54.0
238
729
A46
ICD-10 Finland
Erysipelas
4.8
52.5
202
538
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.6
51.8
144
260
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
23.4
51.2
74
35
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
5.3
50.7
174
407
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.5
50.7
212
611
L20.0
ICD-10 Finland
Besnier prurigo
+∞
50.6
48
*
D07BA04
ATC
hydrocortisone and antiseptics; topical
6.1
46.2
137
267
L30.3
ICD-10 Finland
Infective dermatitis
29.3
42.3
57
21
J01DB01
ATC
cefalexin; oral
3.8
38.5
648
4874
D07AB08
ATC
desonide; topical
5.0
38.1
133
310
D07AC13
ATC
mometasone; topical
3.1
37.7
260
1089
R4180
NOMESCO Finland
Podiatric therapy
21.9
37.6
55
27
D07AB02
ATC
hydrocortisone butyrate; topical
3.1
36.5
263
1132
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.8
36.5
110
216
C03CA01
ATC
furosemide; systemic
2.9
36.4
300
1408
J01FF01
ATC
clindamycin; systemic
3.0
35.4
266
1171
S97
ICPC
Chronic ulcer skin
6.0
34.7
101
189
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
3.7
34.4
175
578
L85.89
ICD-10 Finland
Other specified epidermal thickening
352.7
34.2
34
*
XQ802
NOMESCO Finland
Epicutan test
20.2
34.0
51
27
B35.6
ICD-10 Finland
Tinea inguinalis [Tinea cruris]
18.4
32.3
50
29
D07XC01
ATC
betamethasone, combinations; topical
4.0
31.3
138
400
L85.3
ICD-10 Finland
Xerosis cutis
27.7
30.9
42
16
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
7.7
30.5
73
104
D01AC02
ATC
miconazole; topical
4.7
30.4
110
263
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
+∞
30.4
29
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
6.4
29.8
82
142
D07AD01
ATC
clobetasol; topical
3.5
29.5
153
508
H02AB06
ATC
prednisolone; systemic
2.4
29.5
391
2329
E000006
ATC
NA
5.2
28.9
94
200
D02AE01
ATC
carbamide; topical
5.7
26.3
79
153
S18
ICPC
Laceration/cut
2.3
25.8
361
2157
SPAT1301
SPAT
No procedures
2.4
25.7
294
1588
R50.9
ICD-10 Finland
Fever, unspecified
3.2
25.3
152
555
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.3
25.3
99
255
D07BC01
ATC
betamethasone and antiseptics; topical
3.5
25.2
128
414
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.5
24.4
127
418
L84
ICD-10 Finland
Corns and callosities
6.6
24.4
64
104
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
8.7
24.3
53
65
J01MA02
ATC
ciprofloxacin; systemic
2.3
24.1
337
1990
D07AA02
ATC
hydrocortisone; topical
3.4
23.8
129
435
J02AC01
ATC
fluconazole; systemic
2.3
23.8
313
1794
E66.01
ICD-10 Finland
Obesity due to excess calories
4.4
23.8
91
229
D07CC01
ATC
betamethasone and antibiotics; topical
3.4
23.7
127
427
E66.8
ICD-10 Finland
Other obesity
5.5
23.7
72
141
B35.3
ICD-10 Finland
Tinea pedis
6.4
23.7
64
108
D07CA01
ATC
hydrocortisone and antibiotics; topical
3.2
23.4
138
497
J01DA01
ATC
[U] cefalexin; systemic
2.2
23.0
482
3394
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.7
22.3
175
756
R60.0
ICD-10 Finland
Localized oedema
3.3
22.0
123
426
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
21.6
364
2299
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.0
21.4
141
546
D01BA02
ATC
terbinafine; oral; topical
2.4
21.1
224
1140
R06AE07
ATC
cetirizine; oral
2.2
21.1
324
1960
L30.0
ICD-10 Finland
Nummular dermatitis
9.4
20.8
43
48
S29
ICPC
Skin symptom/complaint other
2.7
20.8
157
662
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.1
20.2
119
426
D01AC03
ATC
econazole; topical
4.1
20.2
82
218
E000003
ATC
NA
5.9
20.1
57
103
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.9
20.0
137
543
L40.0
ICD-10 Finland
Psoriasis vulgaris
5.9
19.7
56
101
J01CE08
ATC
benzathine benzylpenicillin; parenteral
18.8
19.2
29
16
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
19.1
252
1407
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
19.0
245
1354
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
6.3
19.0
51
86
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
18.6
132
532
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.6
18.2
154
687
SPAT1249
SPAT
Treatment-related counselling outside office
2.0
18.2
320
2012
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
18.1
95
312
L89
ICD-10 Finland
Decubitus ulcer and pressure area
8.2
18.0
40
51
B37.2
ICD-10 Finland
Candidiasis of skin and nail
20.7
17.8
26
13
D09AB01
ATC
zinc bandage without supplements; topical
12.9
17.7
31
25
E66.9
ICD-10 Finland
Obesity, unspecified
5.8
17.7
51
94
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
17.6
449
3249
A41.9
ICD-10 Finland
Sepsis, unspecified
5.7
17.6
51
95
R53
ICD-10 Finland
Malaise and fatigue
2.3
17.5
184
920
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.1
17.5
262
1537
SPAT1310
SPAT
Counselling related to known health issue
2.1
17.4
265
1565
SPAT1229
SPAT
Assessment of need for aid
3.3
17.4
92
304
N02AX02
ATC
tramadol; systemic, rectal
2.0
17.2
335
2178
SPAT1263
SPAT
Sampling
2.0
17.0
336
2194
L30.8
ICD-10 Finland
Other specified dermatitis
14.5
16.9
28
20
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
3.2
16.6
92
314
A06AD11
ATC
lactulose; oral
2.6
16.4
131
563
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
5.8
16.3
46
83
M04AA01
ATC
allopurinol; systemic
2.6
16.2
127
539
103
Kela drug reimbursment
Diabetes, insulin-treated
2.1
16.2
228
1291
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
16.2
355
2396
B35.4
ICD-10 Finland
Tinea corporis
14.0
16.1
27
20
L17
ICPC
Foot/toe symptom/complaint
2.1
16.1
209
1147
R03AC02
ATC
salbutamol; inhalant
1.9
16.0
385
2684
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.3
16.0
61
153
G47.3
ICD-10 Finland
Sleep apnoea
2.3
15.9
172
864
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
15.7
103
395
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
15.7
272
1677
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
15.5
210
1166
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
15.5
121
515
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.5
15.5
131
582
L28
ICPC
Limited function/disability (L)
2.4
15.4
147
695
SPAT1254
SPAT
Administration of medicine
2.5
15.2
135
615
A28
ICPC
Limited function/disability NOS
2.4
15.2
142
664
S76
ICPC
Skin infection other
4.2
15.1
59
151
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.9
14.9
95
357
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
14.8
139
652
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.1
14.7
196
1078
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.2
14.7
82
281
L20
ICD-10 Finland
Atopic dermatitis
+∞
14.6
14
*
C07AB07
ATC
bisoprolol; oral
1.9
14.6
365
2548
A02BC02
ATC
pantoprazole; systemic
1.9
14.6
474
3620
N02AA05
ATC
oxycodone; systemic
2.4
14.5
135
628
N02BE01
ATC
paracetamol; systemic, rectal
2.3
14.5
637
5455
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.1
14.4
82
285
M79.6
ICD-10 Finland
Pain in limb
1.9
14.4
270
1702
D02AX
ATC
Other emollients and protectives
6.2
14.2
38
64
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.2
14.2
76
253
I50.9
ICD-10 Finland
Heart failure, unspecified
2.4
14.2
128
585
N03AX16
ATC
pregabalin; oral
2.1
14.1
194
1080
XQ848
NOMESCO Finland
Dermatological photography
7.3
14.0
33
47
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
13.9
102
416
SPAT1153
SPAT
Removal of sutures
1.9
13.9
259
1619
R06.0
ICD-10 Finland
Dyspnoea
2.1
13.8
195
1096
D01AA02
ATC
natamycin; topical
6.4
13.8
36
59
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
13.9
13.8
23
17
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.8
13.8
60
170
A04
ICPC
Weakness/tiredness general
2.5
13.7
112
484
UJF32
NOMESCO Finland
Coloscopy
2.0
13.6
213
1245
6958A
ICD-9 Finland
Erythematous conditions, Other specified erythematous conditions[INTERTRIGO]
+∞
13.6
13
*
G04BD12
ATC
mirabegron; oral
2.7
13.6
100
409
T90
ICPC
Diabetes non-insulin dependent
2.0
13.4
194
1101
U04
ICPC
Incontinence urine
4.0
13.4
54
143
XQ800
NOMESCO Finland
Prick test
4.1
13.3
52
134
N05BA04
ATC
oxazepam; oral
2.0
13.0
194
1113
A10BA02
ATC
metformin; oral
1.9
12.9
219
1317
H02AB04
ATC
methylprednisolone; systemic
2.3
12.9
123
579
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.0
12.9
77
275
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
9.2
12.8
26
29
S74
ICPC
Dermatophytosis
7.7
12.8
29
39
E000002
ATC
NA
2.9
12.7
81
302
N03AX12
ATC
gabapentin; oral
2.3
12.7
133
653
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
6.1
12.7
34
58
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
5.9
12.7
35
62
L04AA06
ATC
mycophenolic acid; systemic
8.4
12.6
27
33
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.9
12.6
52
141
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.1
12.5
71
246
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
11.9
12.4
22
19
N05AH04
ATC
quetiapine; oral
2.3
12.2
128
629
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.0
12.2
39
82
SPAT1260
SPAT
Consultation of another employee
2.1
12.2
150
793
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.9
12.0
74
272
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
12.0
212
1290
N30.0
ICD-10 Finland
Acute cystitis
2.3
11.9
119
572
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
11.9
297
2027
E000007
ATC
NA
3.9
11.9
48
128
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
10.8
11.8
22
21
D01AE15
ATC
terbinafine; topical
2.9
11.8
74
275
M54.5
ICD-10 Finland
Low back pain
1.8
11.8
247
1591
P01AB01
ATC
metronidazole; oral, rectal
1.8
11.8
274
1828
D05BB02
ATC
acitretin; oral
6.7
11.7
29
45
NH3BG
NOMESCO Finland
MRI of foot
19.3
11.6
17
9
S21
ICPC
Skin texture symptom/complaint
2.4
11.6
107
491
A10AE05
ATC
insulin detemir; parenteral
3.2
11.6
60
196
SPAT1216
SPAT
Assessment of functional ability
2.2
11.5
133
682
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
11.4
288
1969
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.9
11.4
47
128
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.4
11.3
55
171
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
11.3
165
928
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
11.3
132
680
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.6
11.3
83
337
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
11.2
189
1123
C08CA13
ATC
lercanidipine; oral
2.3
11.2
114
551
L03.0
ICD-10 Finland
Cellulitis of finger and toe
3.0
11.1
65
231
R5140
NOMESCO Finland
Monitoring the use of the aid
2.5
11.1
88
374
A10BJ02
ATC
liraglutide; parenteral
5.1
11.1
34
69
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
5.3
11.0
33
65
205
Kela drug reimbursment
Chronic hypertension
1.8
11.0
222
1405
SPAT1262
SPAT
Handing over of treatment supplies
2.0
11.0
154
855
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.0
11.0
64
227
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.8
11.0
46
127
J02AC02
ATC
itraconazole; systemic
2.0
10.9
145
788
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.8
10.9
72
277
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.0
10.9
43
113
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
10.8
269
1821
M48.0
ICD-10 Finland
Spinal stenosis
2.3
10.8
109
524
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
10.8
130
678
D01AE16
ATC
amorolfine; topical
2.3
10.8
102
476
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.8
10.8
240
1569
C08CA01
ATC
amlodipine; oral
1.7
10.7
272
1851
ZYC01
NOMESCO Finland
Remote contact by phone
3.6
10.7
47
135
A10AE04
ATC
insulin glargine; parenteral
2.5
10.7
89
389
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
4.1
10.7
41
105
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
4.5
10.4
36
83
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.7
10.4
72
283
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.9
10.4
192
1175
NH3CG
NOMESCO Finland
Extensive MRI of foot
16.3
10.4
16
10
B01AB05
ATC
enoxaparin; parenteral
1.8
10.4
230
1499
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.5
10.3
86
375
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.9
10.2
41
109
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
5.3
10.2
30
58
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
5.3
10.2
30
58
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.0
10.2
59
208
L29.9
ICD-10 Finland
Pruritus, unspecified
8.1
10.2
22
28
SPAT1312
SPAT
General health counselling
1.8
10.1
236
1562
R02
ICPC
Shortness of breath/dyspnoea
2.3
10.1
98
464
SPAT1210
SPAT
Application of cast or individual aid
3.4
10.0
47
143
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
40.6
10.0
12
*
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.5
10.0
79
337
JN3AD
NOMESCO Finland
Abdominal CT examination
2.7
9.9
69
272
160
Kela drug reimbursment
exenatide
5.3
9.9
29
56
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
6.4
9.9
25
40
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
9.9
99
474
L60.0
ICD-10 Finland
Ingrowing nail
3.4
9.8
47
145
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.8
9.8
217
1408
N05AX08
ATC
risperidone; systemic
2.7
9.8
68
267
S06
ICPC
Rash localized
3.2
9.8
51
168
SPAT1139
SPAT
Nutrition survey
4.3
9.8
35
84
PD4DG
NOMESCO Finland
Very extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
13.6
9.7
16
12
E66.00
ICD-10 Finland
Metabolic syndrome
3.1
9.7
53
181
B01AA03
ATC
warfarin; systemic
1.9
9.7
163
967
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
9.6
93
439
J01MA12
ATC
levofloxacin; systemic
2.0
9.6
142
798
L57.0
ICD-10 Finland
Actinic keratosis
2.4
9.6
80
352
D05AX52
ATC
calcipotriol, combinations; topical
3.2
9.5
49
161
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.0
9.4
37
97
A10BH01
ATC
sitagliptin; oral
2.3
9.4
86
393
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
9.4
246
1676
L28.1
ICD-10 Finland
Prurigo nodularis
+∞
9.4
9
*
L20.8
ICD-10 Finland
Other atopic dermatitis
+∞
9.4
9
*
L21.0
ICD-10 Finland
Seborrhoea capitis
12.5
9.4
16
13
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.5
9.4
72
301
Z00.0
ICD-10 Finland
General medical examination
1.9
9.3
142
810
N06AX11
ATC
mirtazapine; oral
1.7
9.3
225
1498
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
9.3
222
1470
ZY010
NOMESCO Finland
Hospital outpatient
3.6
9.2
41
120
A02BC03
ATC
lansoprazole; oral
1.7
9.1
212
1389
L82
ICD-10 Finland
Seborrhoeic keratosis
2.0
9.0
122
665
Z2446
NOMESCO Finland
Social worker
2.8
9.0
56
207
K07
ICPC
Swollen ankles/oedema
3.3
9.0
44
139
M10.9
ICD-10 Finland
Gout, unspecified
2.8
9.0
58
221
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.9
9.0
53
191
D07AB01
ATC
clobetasone; topical
4.0
8.9
34
87
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.9
8.9
28
59
C02AC05
ATC
moxonidine; oral
3.2
8.9
46
151
NF1AA
NOMESCO Finland
Hip X-ray examination
2.4
8.9
78
350
L08.0
ICD-10 Finland
Pyoderma
12.7
8.9
15
12
A29
ICPC
General symptom/complaint other
2.2
8.9
92
447
J01CF05
ATC
flucloxacillin; systemic
3.7
8.9
38
108
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
8.9
133
754
SPAT1234
SPAT
Support of social functional capacity
3.0
8.8
50
174
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.7
8.8
62
246
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.4
8.8
41
125
Z71.8
ICD-10 Finland
Other specified counselling
1.8
8.7
169
1045
C03DA01
ATC
spironolactone; oral
2.2
8.7
91
446
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.3
8.7
42
132
A10BX04
ATC
[U] exenatide; parenteral
8.4
8.6
18
22
L40.8
ICD-10 Finland
Other psoriasis
11.7
8.6
15
13
B35.1
ICD-10 Finland
Tinea unguium
2.9
8.5
53
195
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
5.5
8.5
24
45
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.0
8.5
48
166
P29
ICPC
Psychological sympt/compl other
3.0
8.5
48
166
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
8.5
123
687
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.8
8.5
54
204
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.2
8.4
31
77
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.0
8.4
119
658
C10AA01
ATC
simvastatin; oral
1.6
8.4
324
2430
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
91.0
8.4
9
*
M02AA10
ATC
ketoprofen; topical
2.0
8.4
119
659
SPAT1325
SPAT
Vaccination
1.6
8.4
255
1797
N06AX21
ATC
duloxetine; oral
2.2
8.4
84
401
J01AA02
ATC
doxycycline; systemic
1.6
8.4
537
4574
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.8
8.4
53
199
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
+∞
8.3
8
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.8
8.3
34
93
PD4CC
NOMESCO Finland
Very extensive arterigography of lower extremity with X-ray
9.6
8.3
16
17
N05BA01
ATC
diazepam; systemic, rectal
2.0
8.3
105
557
N03AX09
ATC
lamotrigine; oral
3.4
8.3
39
120
J01MA14
ATC
moxifloxacin; systemic
2.4
8.3
71
316
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
4.8
8.2
26
56
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
8.1
124
707
AA1AD
NOMESCO Finland
CT of head and brain
1.7
8.1
179
1151
D05AX03
ATC
calcitriol; topical
6.9
8.1
19
28
L29.0
ICD-10 Finland
Pruritus ani
11.9
8.1
14
12
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.0
8.1
105
561
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
8.1
317
2383
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
8.1
303
2253
R42
ICD-10 Finland
Dizziness and giddiness
1.8
8.0
165
1036
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
8.0
123
704
M10.0
ICD-10 Finland
Idiopathic gout
4.3
8.0
28
67
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.0
7.9
30
77
L04AA01
ATC
[U] ciclosporin; systemic
6.2
7.9
20
33
T89
ICPC
Diabetes insulin dependent
3.2
7.9
39
125
S08
ICPC
Skin colour change
3.1
7.9
42
142
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.4
7.9
37
114
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.5
7.9
58
239
SPAT1251
SPAT
Organisation of medication
3.4
7.9
37
114
E66
ICD-10 Finland
Obesity
3.3
7.8
38
120
N47
ICD-10 Finland
Redundant prepuce, phimosis and paraphimosis
4.0
7.8
30
78
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.9
7.8
24
50
127
Kela drug reimbursment
Transplant complication
7.1
7.8
18
26
EBA00
NOMESCO Finland
Extraction of tooth
1.6
7.8
227
1577
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.6
7.8
33
94
S99
ICPC
Skin disease other
6.5
7.7
19
30
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
7.7
468
3888
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
7.7
88
447
L04AX01
ATC
azathioprine; systemic
3.2
7.6
39
128
N06AX16
ATC
venlafaxine; oral
2.0
7.6
94
492
R03BB04
ATC
tiotropium bromide; inhalant
2.3
7.6
72
335
L03.9
ICD-10 Finland
Cellulitis, unspecified
5.2
7.6
22
43
M13.9
ICD-10 Finland
Arthritis, unspecified
2.5
7.6
56
231
K02.1
ICD-10 Finland
Caries of dentine
1.5
7.6
373
2945
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.2
7.6
27
66
UKC02
NOMESCO Finland
Cystoscopy
1.9
7.5
120
693
A01
ICPC
Pain general/multiple sites
2.4
7.4
63
278
KMAK
NOMESCO Finland
NA
1.5
7.4
341
2643
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
7.4
100
542
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
7.4
49
191
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
7.4
171
1110
R03BA01
ATC
beclometasone; inhalant
2.0
7.4
100
545
B01AC04
ATC
clopidogrel; oral
1.9
7.3
116
668
N03AG01
ATC
valproic acid; systemic, rectal
2.7
7.3
50
196
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
11.0
7.3
13
12
L73.8
ICD-10 Finland
Other specified follicular disorders
9.5
7.3
14
15
H04.10
ICD-10 Finland
Dry eye syndrome
2.3
7.3
67
308
RD210
NOMESCO Finland
NA
5.5
7.3
20
37
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.6
7.3
53
216
J46
ICD-10 Finland
Status asthmaticus
4.2
7.2
26
64
D05AX02
ATC
calcipotriol; topical
3.1
7.2
37
122
N48.1
ICD-10 Finland
Balanoposthitis
4.3
7.2
25
60
KGH10
NOMESCO Finland
Operation for phimosis
4.3
7.2
25
60
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.3
7.2
25
60
J20
ICD-10 Finland
Acute bronchitis
2.2
7.2
69
325
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
30.3
7.2
9
*
L04AD01
ATC
ciclosporin; systemic
5.4
7.1
20
38
SPAT1104
SPAT
Monitoring of emergency patient
2.4
7.1
61
272
SPAT1285
SPAT
Provision of consultation response
2.6
7.1
49
195
W19
ICD-10 Finland
Unspecified fall
2.2
7.1
73
355
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.6
7.1
30
86
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
7.1
348
2731
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
7.0
165
1076
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
7.0
63
286
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
7.1
7.0
16
23
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.5
7.0
23
52
ZZA00
NOMESCO Finland
Split skin graft
3.5
7.0
31
92
SPAT1211
SPAT
Application of soft bandage
2.1
7.0
73
359
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.0
7.0
93
503
A02BC05
ATC
esomeprazole; systemic
1.5
6.9
276
2061
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.9
6.9
106
604
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.6
6.9
29
83
QDA10
NOMESCO Finland
Incision of skin of lower limb
8.4
6.8
14
17
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.8
6.8
27
73
R15
ICD-10 Finland
Faecal incontinence
3.9
6.8
26
68
A01AB09
ATC
miconazole; local oral
2.2
6.8
69
332
E87.5
ICD-10 Finland
Hyperkalaemia
4.6
6.8
22
49
S75
ICPC
Moniliasis/candidiasis skin
9.4
6.8
13
14
E66.0
ICD-10 Finland
Obesity due to excess calories
6.2
6.8
17
28
M77.4
ICD-10 Finland
Metatarsalgia
2.9
6.8
40
145
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.1
6.8
74
370
J01CA04
ATC
amoxicillin; systemic
1.6
6.8
548
4782
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
40.4
6.8
8
*
L16
ICPC
Ankle symptom/complaint
2.1
6.8
73
361
WZC30
NOMESCO Finland
Teaching
1.9
6.7
95
525
Z94.0
ICD-10 Finland
Kidney transplant status
7.3
6.7
15
21
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
7.3
6.7
15
21
M54.2
ICD-10 Finland
Cervicalgia
2.5
6.7
51
215
R60.9
ICD-10 Finland
Oedema, unspecified
2.9
6.7
39
140
NG4AA
NOMESCO Finland
Lower leg X-ray examination
3.4
6.7
30
90
M01AB08
ATC
etodolac; oral
2.3
6.7
59
268
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.2
6.7
33
107
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.9
6.7
39
141
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.6
6.7
28
80
N30.9
ICD-10 Finland
Cystitis, unspecified
2.6
6.6
44
173
T82
ICPC
Obesity
3.5
6.6
29
86
N05AH03
ATC
olanzapine; systemic
2.6
6.6
46
184
ZXD05
NOMESCO Finland
Urgent procedure
1.6
6.6
206
1448
B80
ICPC
Iron deficiency anaemia
4.9
6.6
20
42
XKD00
NOMESCO Finland
Uroflowmetry
1.8
6.6
118
709
ZXC50
NOMESCO Finland
Cryotherapy
3.6
6.6
28
81
TAKUU
NOMESCO Finland
NA
10.1
6.5
12
12
QBJ30
NOMESCO Finland
Correction of abdominal apron
10.1
6.5
12
12
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.4
6.5
30
92
L04AB04
ATC
adalimumab; parenteral
5.1
6.5
19
38
A08
ICPC
Swelling
2.9
6.5
37
130
E000004
ATC
NA
5.4
6.5
18
34
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.1
6.4
33
110
M02AA07
ATC
piroxicam; topical
1.5
6.4
257
1912
S19
ICPC
Skin injury other
3.0
6.4
34
116
G04BD08
ATC
solifenacin; oral
2.4
6.4
54
239
K92.1
ICD-10 Finland
Melaena
2.6
6.4
45
181
J45.1
ICD-10 Finland
Nonallergic asthma
2.5
6.4
49
208
SPAT1081
SPAT
Cardiorespiratory global assessment
2.5
6.4
48
200
R06AX27
ATC
desloratadine; oral
1.7
6.4
156
1026
A10BJ06
ATC
semaglutide; parenteral
3.3
6.4
30
94
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
6.4
94
529
L21
ICD-10 Finland
Seborrhoeic dermatitis
8.2
6.3
13
16
J01FA06
ATC
roxithromycin; oral
1.5
6.3
267
2009
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
4.1
6.3
23
58
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.5
6.3
239
1755
S87
ICPC
Dermatitis/atopic eczema
5.6
6.3
17
31
Y69
ICD-10 Finland
Unspecified misadventure during surgical and medical care
5.6
6.3
17
31
A10BK03
ATC
empagliflozin; oral
2.3
6.3
54
242
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
4.6
6.3
20
44
N05CF01
ATC
zopiclone; oral
1.5
6.3
225
1630
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
6.3
122
748
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.4
6.3
28
84
J01EA01
ATC
trimethoprim; systemic
1.6
6.3
172
1165
U05
ICPC
Urination problems other
2.7
6.3
41
159
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
6.3
58
268
C05AA08
ATC
fluocortolone; rectal, topical
1.8
6.3
102
593
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
26.9
6.2
8
*
E86
ICD-10 Finland
Volume depletion
4.0
6.2
23
59
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.0
6.2
23
59
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.7
6.2
153
1006
N05AA02
ATC
levomepromazine; systemic
2.9
6.2
36
129
C07AB02
ATC
metoprolol; systemic
1.7
6.2
146
951
K59.09
ICD-10 Finland
Constipation, unspecified
2.4
6.2
50
217
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
6.2
47
198
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
6.2
455
3847
R33
ICD-10 Finland
Retention of urine
2.2
6.2
60
285
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
6.2
259
1946
L43.8
ICD-10 Finland
Other lichen planus
4.7
6.1
19
41
SPAT1252
SPAT
Overall medication plan or its review
2.3
6.1
55
252
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.9
6.1
23
60
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
6.1
106
629
B05DB
ATC
Hypertonic solutions
12.6
6.1
10
8
D06BB10
ATC
imiquimod; topical
3.0
6.1
33
115
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
6.8
6.1
14
21
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
6.0
254
1908
A07EC01
ATC
sulfasalazine; oral, rectal
2.2
6.0
57
268
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.0
6.0
22
56
ZX120
NOMESCO Finland
Intravenous
2.1
6.0
70
358
N18.8
ICD-10 Finland
Other chronic renal failure
3.4
6.0
27
82
Mortality – FinRegistry
↥Association
Association between endpoint L12_ERYT_INTERTRIG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ERYT_INTERTRIG | 2.082 [1.74, 2.5] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.21 |
During the follow-up period (1.1.1998 — 31.12.2019), 658 out of 2206 females with L12_ERYT_INTERTRIG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ERYT_INTERTRIG | 2.077 [1.71, 2.52] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 541 out of 1988 males with L12_ERYT_INTERTRIG died.
Mortality risk
Mortality risk for people of age
years, who have L12_ERYT_INTERTRIG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.15% | 0.422% |
| 5 | 1.139% | 2.249% |
| 10 | 3.01% | 5.505% |
| 15 | 5.663% | 10.374% |
| 20 | 9.833% | 17.067% |
Relationships between endpoints
↥Index endpoint: L12_ERYT_INTERTRIG – Erythema intertrigo
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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