erythrasma: a skin disease that causes brown, scaly skin patches. It is caused by the Gram-positive bacterium Corynebacterium minutissimum. It is prevalent among diabetics and the obese, and in warm climates; it is worsened by wearing occlusive clothing.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
77 |
4. Check minimum number of eventsNone |
77 |
5. Include endpointsNone |
77 |
6. Filter based on genotype QC (FinnGen only) |
77 |
Control definitions (FinnGen only)
- Control exclude
- L12_INFECT_SKIN
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- L08
- Name in latin
- Erythrasma
Similar endpoints
↥List of similar endpoints to
Erythrasma
based on the number of shared cases.
Similar with more cases:
- Other local infections of skin and subcutaneous tissue
- Infections of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 476 | 191 | 281 |
| Only index persons | 408 | 160 | 248 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 50.66 | 50.13 | 50.99 |
| Only index persons | 47.94 | 47.52 | 48.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 77 | 27 | 50 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 52.13 | 53.47 | 51.40 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 70
- Matched controls
- 708
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L08.1
ICD-10 Finland
Erythrasma
+∞
81.9
62
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.8
8.9
28
71
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.3
8.7
17
21
3900A
ICD-9 Finland
Rheumatic fever without mention of heart involvement[FEBRIS RHEUMATICA, MORBO CORDIS NON INDICATO]
+∞
7.4
7
*
Mortality – FinRegistry
↥Association
Association between endpoint L12_ERYTHRASMA and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have L12_ERYTHRASMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: L12_ERYTHRASMA – Erythrasma
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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