sweat gland disease: disorders or sweat glands
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
74 |
4. Check minimum number of eventsNone |
74 |
5. Include endpoints |
89 |
6. Filter based on genotype QC (FinnGen only) |
89 |
Control definitions (FinnGen only)
- Control exclude
- L12_DISORDSKINAPPENDIX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L60-L75
- Name in latin
- Morbositates glandularum sudoriferarum eccrinarum
Similar endpoints
↥List of similar endpoints to
Eccrine sweat disorders
based on the number of shared cases.
Similar with more cases:
- Disorders of skin appendages
- Diseases of the skin and subcutaneous tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 675 | 388 | 284 |
| Only index persons | 590 | 348 | 242 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 39.54 | 44.02 | 33.11 |
| Only index persons | 40.08 | 44.15 | 34.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 89 | 54 | 35 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 46.10 | 50.14 | 39.85 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 81
- Matched controls
- 808
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L74.0
ICD-10 Finland
Miliaria rubra
+∞
17.3
16
*
L74.9
ICD-10 Finland
Eccrine sweat disorder, unspecified
196.4
16.1
16
*
L74.8
ICD-10 Finland
Other eccrine sweat disorders
+∞
11.7
11
*
L74.1
ICD-10 Finland
Miliaria crystallina
+∞
8.5
8
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.4
7.6
18
30
L74.3
ICD-10 Finland
Miliaria, unspecified
+∞
7.4
7
*
L74.4
ICD-10 Finland
Anhidrosis
+∞
6.3
6
*
Mortality – FinRegistry
↥Association
Association between endpoint L12_ECCRINESWEAT and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have L12_ECCRINESWEAT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: L12_ECCRINESWEAT – Eccrine sweat disorders
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data