This is a non-core endpoint: only basic statistics are computed.
Actinic reticuloid
L12_ACTINRETICU
phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
39 |
4. Check minimum number of eventsNone |
39 |
5. Include endpointsNone |
39 |
6. Filter based on genotype QC (FinnGen only) |
39 |
Control definitions (FinnGen only)
- Control exclude
- L12_RADIATIONRELATEDSKIN
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L57
- Name in latin
- Reticuloides actinica
Similar endpoints
↥List of similar endpoints to
Actinic reticuloid
based on the number of shared cases.
Similar with more cases:
- Skin changes due to chronic exposure to nonionizing radiation
- Radiation-related disorders of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 245 | 99 | 144 |
| Only index persons | 204 | 85 | 119 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 71.82 | 76.74 | 68.40 |
| Only index persons | 70.93 | 74.72 | 68.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 39 | 14 | 25 |
| Unadjusted period prevalence (%) | 0.01 | 0.00 | 0.01 |
| Median age at first event (years) | 68.59 | 69.66 | 67.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
Mortality – FinRegistry
↥Association
Association between endpoint L12_ACTINRETICU and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ACTINRETICU | 1.162 [0.82, 1.65] | 0.403 |
| Birth year | 0.991 [0.98, 1.0] | 0.056 |
During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 111 males with L12_ACTINRETICU died.
Mortality risk
Mortality risk for people of age
years, who have L12_ACTINRETICU.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.245% |
| 5 | No data | 1.547% |
| 10 | No data | 3.92% |
| 15 | No data | 7.131% |
| 20 | No data | 12.564% |
Relationships between endpoints
↥Index endpoint: L12_ACTINRETICU – Actinic reticuloid
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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