This is a non-core endpoint: only basic statistics are computed.
Actinic reticuloid
L12_ACTINRETICU
phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
39 |
4. Check minimum number of eventsNone |
39 |
5. Include endpointsNone |
39 |
6. Filter based on genotype QC (FinnGen only) |
39 |
Control definitions (FinnGen only)
- Control exclude
- L12_RADIATIONRELATEDSKIN
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L57
- Name in latin
- Reticuloides actinica
Similar endpoints
↥List of similar endpoints to
Actinic reticuloid
based on the number of shared cases.
Similar with more cases:
- Skin changes due to chronic exposure to nonionizing radiation
- Radiation-related disorders of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 245 | 99 | 144 |
| Only index persons | 204 | 85 | 119 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 71.82 | 76.74 | 68.40 |
| Only index persons | 70.93 | 74.72 | 68.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 39 | 14 | 25 |
| Unadjusted period prevalence (%) | 0.01 | 0.00 | 0.01 |
| Median age at first event (years) | 68.59 | 69.66 | 67.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3042936) Bacteria identified in Isolate by Culture
12
45
3.41
2.75
1.2
1.8
—
—
—
0
0
(3002256) Pathology report gross observation
7
17
4.77
2.49
1.9
1.2
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
17
85
2.77
2.36
4.5
1.8
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
17
86
2.73
2.30
5.8
4.2
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
5
9
6.18
2.28
3.2
2.3
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
9
31
3.46
2.25
2.3
1.3
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
5
10
5.55
2.14
3.2
3.0
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
15
79
2.46
1.81
2.9
3.4
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
16
95
2.16
1.42
3.4
4.3
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
28
207
2.25
1.42
6.0
7.5
u/l
73.3
73.5
0.01
23
198
(3018010) Neutrophils/100 leukocytes in Blood
19
127
1.97
1.19
6.4
4.9
%
62.0
57.7
0.75
19
116
(3009542) Hematocrit [Volume Fraction] of Blood
28
216
2.05
1.15
21.2
16.9
%
41.9
38.7
2.63
18
148
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
31
253
2.10
1.12
21.8
16.5
mg/l
39.5
26.1
0.72
24
211
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
10
55
2.10
1.03
3.5
2.5
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
13
80
1.94
1.00
2.9
2.3
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
18
125
1.82
0.96
8.0
5.2
%
8.7
8.8
0.10
18
116
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
17
116
1.83
0.96
2.3
2.3
pmol/l
90.3
90.5
—
7
67
(3003338) MCHC [Mass/volume]
26
203
1.84
0.94
29.5
22.7
g/l
332.1
332.2
0.02
26
203
(3022096) Basophils/100 leukocytes in Blood
17
119
1.76
0.87
8.5
5.0
%
0.6
0.6
0.24
17
109
(3007853) Bacteria identified in Skin by Aerobe culture
6
32
2.03
0.86
1.8
1.5
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
17
122
1.70
0.78
8.6
5.1
%
3.5
2.9
0.33
17
111
(3012544) pH of Venous blood
5
29
1.83
0.66
2.2
4.6
—
—
—
0
0
(40758558) Short blood count panel - Blood
11
73
1.71
0.65
8.0
6.7
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
9
61
1.62
0.59
3.2
2.7
e6/l
1.4
4.1
—
9
51
(3020564) Creatinine [Moles/volume] in Serum or Plasma
30
264
1.59
0.55
23.5
20.2
umol/l
81.6
85.5
0.36
30
264
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
27
230
1.57
0.55
21.9
15.6
ml/min/173m2
75.0
74.0
0.09
22
187
(3015377) Calcium [Moles/volume] in Serum or Plasma
13
96
1.53
0.50
2.4
4.6
mmol/l
2.3
2.4
—
6
87
(40768797) Stomach Pathology biopsy report
5
32
1.64
0.44
1.4
1.3
—
—
—
0
0
(3026782) Osmolality of Urine
8
60
1.42
0.44
2.9
3.6
mosm/kgh2o
539.3
588.7
—
8
51
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
15
118
1.44
0.42
2.7
5.1
ng/l
651.9
62.5
—
7
90
(4010399)
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
12
91
1.46
0.40
4.2
3.5
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
21
178
1.39
0.38
6.6
4.7
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
6
42
1.50
0.38
2.5
2.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
12
94
1.40
0.33
5.8
4.7
e6/l
11.3
36.8
1.71
12
72
(40760892) CBC W Ordered Manual Differential panel - Blood
7
54
1.36
0.33
2.9
6.3
—
—
—
0
0
(3044889) 12 lead EKG panel
21
182
1.33
0.31
4.0
3.8
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
11
86
1.39
0.30
4.7
3.6
e6/l
47.0
771.3
0.50
11
69
(1761868) Lipid panel - Serum or Plasma
5
74
0.63
0.29
5.4
3.0
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
14
115
1.34
0.29
4.6
4.0
—
—
—
0
0
(3015736) pH of Urine
11
90
1.31
0.22
3.8
4.4
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
0
11
0.00
0.22
0.0
1.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
11
0.00
0.22
0.0
1.8
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
10
0.00
0.22
0.0
1.2
—
—
—
0
0
(3000570) Elastase.pancreatic [Mass/mass] in Stool
0
12
0.00
0.21
0.0
1.7
—
149.7
—
0
6
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
4.9
—
24.2
—
0
13
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3013512) EKG study
11
91
1.29
0.20
3.4
4.3
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
8
68
1.22
0.18
5.1
3.3
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
9
104
0.83
0.15
3.0
4.2
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
12
132
0.87
0.08
4.0
4.3
—
0.0
—
0
15
(3041096) Erythrocytes [Presence] in Urine by Automated
7
79
0.86
0.08
3.0
3.5
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
7
79
0.86
0.08
5.1
3.0
mmol/l
9.6
8.1
—
7
72
(3035350) Ketones [Presence] in Urine by Test strip
12
128
0.91
0.03
4.0
4.3
—
0.0
—
0
18
(40761511) CBC panel - Blood by Automated count
27
263
1.09
0.02
16.9
14.0
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
12
126
0.93
0.01
3.3
2.5
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
10
103
0.96
0.00
10.0
9.2
e9/l
0.0
0.0
—
10
85
(3021601) Nitrite [Presence] in Urine by Test strip
12
125
0.94
0.00
6.4
6.1
—
0.0
—
0
19
(3048929) Epstein Barr virus Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(44790049)
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(44806118)
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(44790047)
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
362.0
—
0
6
(3045424) Erythrocytes [Presence] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
6
58
1.04
0.00
4.5
4.4
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003434) Protein [Mass/volume] in Pleural fluid
0
6
0.00
0.00
0.0
1.5
—
26.8
—
0
6
(3019230) Fractional oxyhemoglobin in Venous blood
0
6
0.00
0.00
0.0
1.7
—
74.8
—
0
6
(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.3
—
11.8
—
0
6
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(44790048)
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
0
6
0.00
0.00
0.0
1.5
—
4.8
—
0
6
(3027315) Oxygen [Partial pressure] in Blood
0
6
0.00
0.00
0.0
1.5
—
8.3
—
0
6
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
6
0.00
0.00
0.0
1.5
—
133.8
—
0
6
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3029634) Reagin Ab [Titer] in Serum by VDRL
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.8
—
2.2
—
0
5
(40768800) Prostate Pathology biopsy report
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
70.4
—
0
5
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
5
0.00
0.00
0.0
1.8
—
11.6
—
0
5
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
(3018418) pH of Serum or Plasma
8
85
0.93
0.00
6.9
4.7
—
7.4
—
0
12
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3035880) pH of Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
9
0.00
0.00
0.0
2.6
—
—
—
0
0
(3036782) Glucose [Moles/volume] in Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
6.8
—
0
5
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_ACTINRETICU and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ACTINRETICU | 1.162 [0.82, 1.65] | 0.403 |
| Birth year | 0.991 [0.98, 1.0] | 0.056 |
During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 111 males with L12_ACTINRETICU died.
Mortality risk
Mortality risk for people of age
years, who have L12_ACTINRETICU.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.245% |
| 5 | No data | 1.547% |
| 10 | No data | 3.92% |
| 15 | No data | 7.131% |
| 20 | No data | 12.564% |
Relationships between endpoints
↥Index endpoint: L12_ACTINRETICU – Actinic reticuloid
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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