No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
59 |
4. Check minimum number of eventsNone |
59 |
5. Include endpointsNone |
59 |
6. Filter based on genotype QC (FinnGen only) |
59 |
Control definitions (FinnGen only)
- Control exclude
- L12_DISORDSKINAPPENDIX
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L73
- Name in latin
- Acne cheloides (scleroticans nuchae)
Similar endpoints
↥List of similar endpoints to
Acne keloid
based on the number of shared cases.
Similar with more cases:
- Other follicular disorders
- Disorders of skin appendages
- Diseases of the skin and subcutaneous tissue
- Paracetamol of NSAID medication
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 511 | 157 | 348 |
| Only index persons | 476 | 151 | 325 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.00 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 35.43 | 37.86 | 34.35 |
| Only index persons | 35.04 | 38.25 | 33.56 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 59 | 25 | 34 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 37.37 | 40.98 | 34.72 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 56
- Matched controls
- 560
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L73.0
ICD-10 Finland
Acne keloid
+∞
70.6
52
*
L70.0
ICD-10 Finland
Acne vulgaris
+∞
11.9
11
*
D10BA01
ATC
isotretinoin; oral
11.9
10.1
19
23
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
9.4
9.3
20
31
J01AA07
ATC
tetracycline; systemic
7.6
9.3
24
50
L73.8
ICD-10 Finland
Other specified follicular disorders
+∞
7.4
7
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.7
6.9
30
111
Mortality – FinRegistry
↥Association
Association between endpoint L12_ACNEKELOID and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have L12_ACNEKELOID.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: L12_ACNEKELOID – Acne keloid
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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