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This is a non-core endpoint: only basic statistics are computed.

Pneumoconiosis associated with tuberculosis

J10_TUBERCPNEUMOC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J65
  • Cause of death: ICD-10 J65

2 out of 7 registries used, show all original rules.

6

4. Check minimum number of events

None

6

5. Include endpoints

None

6

6. Filter based on genotype QC (FinnGen only)

6

Control definitions (FinnGen only)

Control exclude
J10_EXTERLUNG

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J60-J70
Name in latin
Pneumoconiosis cum tuberculosi

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 69 20 46
Only index persons 46 15 31
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 65.62 64.17 65.93
Only index persons 60.94 55.03 63.79

-FinnGen-

Key figures

All Female Male
Number of individuals 6 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 65.84 - -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3011397) Hemoglobin [Presence] in Urine by Test strip
0
10
0.00
0.24
0.0
8.1
—
—
—
0
0
(40761535) Cells panel - Urine sediment
0
9
0.00
0.23
0.0
3.9
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002256) Pathology report gross observation
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
4.6
—
20.5
—
0
5
(3024354) Oxygen [Partial pressure] in Venous blood
0
5
0.00
0.00
0.0
4.6
—
3.6
—
0
5
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
0
7
0.00
0.00
0.0
18.7
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
0
5
0.00
0.00
0.0
4.6
—
47.7
—
0
5
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint J10_TUBERCPNEUMOC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have J10_TUBERCPNEUMOC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: J10_TUBERCPNEUMOC – Pneumoconiosis associated with tuberculosis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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