bacterial pneumonia: Inflammation of the lung parenchyma that is caused by bacterial infections.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
119 |
4. Check minimum number of eventsNone |
119 |
5. Include endpointsNone |
119 |
6. Filter based on genotype QC (FinnGen only) |
119 |
Control definitions (FinnGen only)
- Control exclude
- J10_INFLUPNEU
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- J09-J18
- Name in latin
- Pneumonia ab Haemophilo influenzae
Similar endpoints
↥List of similar endpoints to
Pneumonia due to Haemophilus influenzae
based on the number of shared cases.
Similar with more cases:
- Bacterial pneumoniae
- Bacterial pneumonia (organism specified)
- Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)
- Pneumonias (Asthma/COPD co-morbidities)
- COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1201 | 473 | 712 |
| Only index persons | 836 | 381 | 455 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.02 |
| Only index persons | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 50.62 | 48.81 | 51.68 |
| Only index persons | 32.44 | 41.55 | 24.81 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 119 | 58 | 61 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 48.71 | 40.63 | 56.39 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 101
- Matched controls
- 1008
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J14
ICD-10 Finland
Pneumonia due to Haemophilus influenzae
+∞
66.1
56
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
59.3
46.5
54
19
48210
ICD-8 Finland
Other bacterial pneumonia, Haemophilus influenzae
+∞
35.5
32
*
4822A
ICD-9 Finland
Other bacterial pneumonia, Pneumonia due to Haemophilus influenzae [H. influenzae]
+∞
13.9
13
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
58.0
13.2
15
*
A41.3
ICD-10 Finland
Sepsis due to Haemophilus influenzae
+∞
10.6
10
*
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
+∞
9.5
9
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
9.5
9.4
19
24
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
12.3
8.1
14
13
TGC00
NOMESCO Finland
Bronchial lavation
48.9
7.8
9
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.9
7.0
31
103
A41.9
ICD-10 Finland
Sepsis, unspecified
24.4
6.8
9
*
H02AB06
ATC
prednisolone; systemic
3.1
6.8
55
283
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
5.3
6.6
20
45
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.9
6.5
60
335
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.5
6.5
23
62
D64.9
ICD-10 Finland
Anaemia, unspecified
5.7
6.4
18
37
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
32
12
36.11
48.00
1.7
1.5
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
31
11
37.76
47.28
1.7
1.7
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
33
15
30.06
46.24
1.6
1.6
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
31
15
27.59
42.24
2.0
1.7
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
28
11
32.98
41.08
2.1
1.6
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
31
17
24.31
40.04
2.0
1.6
—
—
—
0
0
(40767503) Oxygen content in Capillary blood by calculation
27
13
26.57
36.63
4.3
1.8
%
15.0
17.8
—
13
6
(3027315) Oxygen [Partial pressure] in Blood
24
17
17.43
27.00
8.1
2.4
kpa
8.4
9.3
0.69
24
17
(3012501) Base excess in Blood by calculation
24
17
17.43
27.00
8.0
2.4
mmol/l
2.9
2.6
—
16
10
(3013290) Carbon dioxide [Partial pressure] in Blood
24
17
17.43
27.00
8.1
2.4
kpa
5.3
5.0
0.46
24
17
(1616796) Gas panel - Central venous blood
23
16
17.58
26.08
5.9
2.4
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
31
9
45.85
25.83
1.7
1.4
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
27
6
57.53
23.53
2.1
1.3
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
27
7
49.20
22.88
2.1
1.3
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
19
12
18.65
22.45
6.1
3.1
%
61.7
62.1
0.03
19
12
(3042631) Mycobacterium sp identified in Specimen
18
11
19.10
21.56
5.6
3.5
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
18
12
17.50
20.64
4.8
3.0
e9/l
5.6
4.5
0.52
18
12
(3002179) Metamyelocytes/100 leukocytes in Blood
32
55
7.59
19.07
5.5
3.6
%
0.5
0.5
0.02
15
11
(40761536) Microorganisms panel - Urine sediment
35
68
6.88
18.55
5.7
3.7
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
32
58
7.18
18.10
5.8
3.6
%
0.1
0.0
0.48
15
13
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
35
71
6.57
17.72
2.6
1.6
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
34
69
6.50
17.17
2.7
1.6
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
32
62
6.69
16.90
5.9
3.4
%
0.1
0.4
0.83
15
16
(3017181) Myelocytes/100 leukocytes in Blood
33
66
6.53
16.89
5.9
3.4
%
0.6
0.8
0.23
15
19
(3023368) Bacteria identified in Blood by Culture
56
182
4.92
16.50
8.0
3.3
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
27
48
6.98
15.41
18.9
5.3
mmol/l
25.4
24.4
0.49
27
48
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
39
105
5.04
14.23
3.2
1.7
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
19
9
24.77
13.85
2.8
1.2
%
88.0
91.4
—
19
9
(3021901) Oxygen saturation in Capillary blood
15
15
11.30
13.41
4.9
1.8
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
33
82
5.18
13.15
6.7
2.8
—
—
—
0
0
(3015235) Bicarbonate [Moles/volume] in Capillary blood
15
16
10.58
12.82
6.5
2.1
mmol/l
27.4
26.1
—
15
10
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
16
22
8.25
11.28
2.4
2.0
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
15
7
24.21
10.99
5.0
2.4
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
15
22
7.66
9.98
2.2
1.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
52
231
3.22
8.76
4.9
2.9
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
57
270
3.13
8.56
9.6
5.2
—
—
—
0
0
(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate
11
5
24.00
8.18
6.7
6.2
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
11
14
8.56
8.12
1.4
1.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
51
235
3.05
7.92
5.2
3.9
estimate
0.0
0.0
0.00
27
82
(3018418) pH of Serum or Plasma
52
248
2.95
7.52
6.2
3.8
ph
7.4
7.4
0.09
32
47
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
10
5
21.63
7.26
2.3
2.4
—
—
—
0
0
(3019060) Gas panel - Arterial blood
19
50
4.33
6.84
6.4
3.6
—
—
—
0
0
(3020891) Body temperature
16
37
4.84
6.72
6.4
4.6
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
59
318
2.70
6.57
4.8
2.9
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
46
219
2.79
6.52
10.9
4.6
—
—
—
0
0
(3046861) Legionella sp Ag [Presence] in Urine
6
0
+∞
6.30
1.0
0.0
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
66
383
2.62
6.24
12.3
5.2
mmol/l
1.2
1.2
1.53
60
350
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
20
59
3.87
6.18
2.9
3.7
ml/min/173m2
51.4
61.8
—
9
31
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
10
16
6.73
6.06
3.2
1.8
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
18
50
4.06
6.03
2.2
1.2
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
10
9
11.99
5.91
1.4
1.0
—
—
—
0
0
(3009343) pH of Capillary blood
19
59
3.64
5.44
15.8
2.4
ph
7.4
7.4
—
11
6
(3035350) Ketones [Presence] in Urine by Test strip
69
428
2.46
5.42
4.9
3.5
estimate
0.0
0.0
0.00
34
85
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
19
60
3.58
5.31
15.8
2.4
kpa
5.3
5.0
0.60
19
55
(3021601) Nitrite [Presence] in Urine by Test strip
69
432
2.42
5.25
5.7
4.7
estimate
0.0
0.0
0.00
35
85
(3020229) Cytomegalovirus DNA [Presence] in Specimen by NAA with probe detection
5
0
+∞
5.24
1.4
0.0
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
69
435
2.40
5.13
4.8
3.5
estimate
0.0
0.0
0.00
36
79
(3041096) Erythrocytes [Presence] in Urine by Automated
48
260
2.42
5.01
5.2
3.2
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
58
349
2.29
4.69
13.7
6.2
inr
1.1
1.3
1.69
40
98
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
58
350
2.28
4.64
4.8
3.6
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
7
6
12.28
4.33
2.1
3.8
—
—
—
0
0
(1175426) CD3 cells/100 lymphocytes in Blood
7
6
12.28
4.33
2.1
4.0
%
84.4
72.3
—
7
6
(3021589) Normoblasts [#/volume] in Blood
62
393
2.21
4.32
23.4
9.2
e9/l
0.0
0.0
0.44
56
330
(3012095) Magnesium [Moles/volume] in Serum or Plasma
29
136
2.50
4.04
6.2
3.0
mmol/l
0.8
0.8
0.48
29
130
(3013115) Eosinophils [#/volume] in Blood
67
449
2.13
3.94
11.0
6.0
e9/l
0.2
0.2
0.28
61
400
(3001604) Monocytes [#/volume] in Blood
65
433
2.10
3.85
9.2
5.7
e9/l
0.6
0.6
0.78
58
381
(3022096) Basophils/100 leukocytes in Blood
60
388
2.10
3.85
11.2
5.2
%
0.5
0.7
1.70
60
363
(3006315) Basophils [#/volume] in Blood
65
434
2.10
3.82
9.1
5.7
e9/l
0.0
0.0
0.28
58
386
(3042936) Bacteria identified in Isolate by Culture
28
133
2.45
3.78
2.0
1.7
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
54
341
2.07
3.64
5.9
3.3
ng/l
30.3
51.8
0.78
41
234
(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
7
9
8.17
3.61
7.3
5.2
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
65
446
2.01
3.42
9.5
5.7
e9/l
1.7
2.0
0.89
58
401
(40760888) Immunoglobulin light chains.free panel - Serum
8
14
6.04
3.40
12.5
4.4
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
60
402
1.99
3.37
11.3
5.2
%
2.2
2.8
2.37
60
378
(3019069) Monocytes/100 leukocytes in Blood
60
402
1.99
3.37
11.4
5.5
%
8.3
8.5
0.26
60
381
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
35
193
2.15
3.32
1.7
1.8
pmol/l
535.0
451.9
0.43
25
159
(3002030) Lymphocytes/100 leukocytes in Blood
60
417
1.89
2.90
11.4
5.4
%
24.0
29.0
2.35
60
394
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
9
23
4.14
2.84
2.7
1.1
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
21
104
2.24
2.55
2.1
1.6
—
—
—
0
0
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
8
21
4.01
2.51
11.9
3.0
—
1.4
—
0
5
(3013512) EKG study
41
262
1.86
2.50
3.8
3.6
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
7
17
4.30
2.40
4.4
1.2
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
5
8
6.46
2.39
1.0
1.3
—
—
—
0
0
(44790048)
5
8
6.46
2.39
1.4
1.8
—
—
—
0
0
(44790049)
5
8
6.46
2.39
1.4
1.8
—
—
—
0
0
(44806118)
5
8
6.46
2.39
1.4
1.8
—
—
—
0
0
(44790047)
5
8
6.46
2.39
1.4
1.8
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
5
8
6.46
2.39
7.0
1.6
pg
33.2
33.4
—
5
8
(3018010) Neutrophils/100 leukocytes in Blood
57
417
1.70
2.14
9.6
5.2
%
61.7
56.5
1.87
57
397
(3014148) Varicella zoster virus Ab [Titer] in Serum
5
10
5.16
2.09
1.0
1.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
18
91
2.15
2.08
2.4
1.4
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
75
597
1.69
2.00
6.0
4.1
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
25
146
1.90
1.97
3.1
1.7
nmol/l
1639.6
1195.7
0.80
14
112
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
6
16
3.89
1.96
2.3
1.4
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
6
16
3.89
1.96
2.3
1.4
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
11
46
2.53
1.91
1.3
1.1
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
5
12
4.30
1.84
3.8
1.2
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
66
516
1.63
1.83
15.9
9.5
e9/l
5.0
4.0
1.56
61
456
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
57
430
1.62
1.82
14.3
5.7
mmol/l
1.2
1.2
0.75
31
368
(3003396) Base excess in Arterial blood by calculation
17
89
2.06
1.81
13.5
4.9
mmol/l
3.7
0.7
1.51
11
69
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
13
3.96
1.73
1.2
1.2
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
13
62
2.23
1.73
6.5
2.9
g/l
68.5
67.6
0.14
13
56
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
32
211
1.71
1.70
1.7
1.9
mg/l
3.8
2.9
0.53
24
185
(3048929) Epstein Barr virus Ab [Presence] in Serum
6
19
3.27
1.68
1.8
1.1
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
75
616
1.59
1.61
3.5
3.3
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
6
20
3.10
1.60
4.8
1.3
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
78
896
0.62
1.57
3.8
3.8
mmol/l
1.5
1.3
0.79
64
814
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
43
0.00
1.56
0.0
1.3
—
2.3
—
0
30
(3009508) Creatinine [Moles/volume] in Urine
39
277
1.61
1.55
3.4
2.7
mmol/l
6.9
7.9
0.73
32
232
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
39
0.00
1.36
0.0
1.7
—
38.5
—
0
39
(3000991) Gas panel - Venous blood
12
62
2.04
1.33
15.1
5.5
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
10
48
2.18
1.32
8.2
2.4
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
18
2.85
1.30
1.4
1.2
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
35
252
1.55
1.30
4.7
2.7
ng/l
1139.2
1044.3
0.13
30
214
(3011288) Drugs identified in Urine by Screen method
6
26
2.37
1.20
1.5
1.7
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
39
294
1.49
1.16
3.8
2.9
u/l
33.1
30.9
0.20
39
277
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
83
921
0.67
1.11
4.3
4.3
mmol/l
1.3
1.4
1.86
67
843
(3026008) Bacteria identified in Urine by Culture
33
243
1.50
1.09
4.0
3.0
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
5
22
2.33
1.04
2.6
1.2
g/l
0.2
0.2
—
5
22
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
5
22
2.33
1.04
2.6
1.2
g/l
1.1
1.1
—
5
22
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
7
35
2.06
1.02
1.0
1.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
7
35
2.06
1.02
1.9
1.7
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
22
151
1.56
0.99
1.9
2.1
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
105
0.45
0.94
1.8
1.8
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
6
30
2.05
0.88
1.0
1.3
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
33
254
1.41
0.87
3.2
2.9
mg/l
95.8
59.7
0.31
20
165
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
15
97
1.63
0.86
2.1
2.8
umol/l
9.7
8.4
—
10
87
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
85
925
0.72
0.83
4.3
4.3
mmol/l
4.5
4.7
0.56
70
854
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
26
0.00
0.79
0.0
1.0
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
34
1.80
0.77
20.7
6.0
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
5
23
2.22
0.77
1.0
1.1
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
18
247
0.68
0.74
4.4
4.0
%
23.9
22.9
0.09
11
105
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
25
2.04
0.73
1.2
1.1
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
7
40
1.80
0.72
1.1
2.3
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
34
271
1.36
0.72
4.9
3.7
mg/mmol
26.1
8.6
0.61
19
168
(3000492) Spirometry study
13
85
1.59
0.72
1.2
1.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
15
210
0.67
0.68
3.1
2.0
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
79
856
0.77
0.62
6.7
5.7
mmol/mol
43.4
40.1
1.68
73
802
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
88
940
0.75
0.61
4.4
4.7
mmol/l
2.7
2.8
0.45
72
862
(3002523) Influenza virus A Ag [Presence] in Specimen
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
(4094501)
0
20
0.00
0.61
0.0
1.0
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
(4010399)
8
52
1.58
0.61
1.5
1.4
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
99
931
1.38
0.60
30.2
11.4
mg/l
36.8
20.2
2.81
88
723
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
23
0.00
0.59
0.0
1.2
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
20
257
0.73
0.57
1.5
1.4
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
14
191
0.70
0.56
3.4
3.0
ug/l
1.0
0.8
—
9
109
(1761868) Lipid panel - Serum or Plasma
44
377
1.27
0.55
3.2
2.7
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
6
38
1.61
0.55
1.5
1.3
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
6
39
1.57
0.54
1.5
1.3
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
6
39
1.57
0.54
1.5
1.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
23
181
1.34
0.53
3.5
3.6
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
22
172
1.34
0.53
5.6
1.3
g/l
3.8
2.6
0.47
16
109
(3002256) Pathology report gross observation
8
117
0.66
0.48
1.6
1.2
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
7
47
1.52
0.48
1.4
1.3
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
71
650
1.23
0.47
4.4
2.8
u/l
62.2
46.3
0.75
65
614
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
36
417
0.80
0.46
9.3
3.7
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
18
140
1.34
0.45
1.1
1.2
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
78
833
0.82
0.44
4.4
4.4
mu/l
1.8
1.9
0.26
67
747
(3045414) Leukocytes [Presence] in Urine
5
32
1.59
0.43
2.6
1.8
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
5
32
1.59
0.43
1.4
1.3
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
7
103
0.66
0.41
1.1
1.4
—
—
—
0
0
(4306422)
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
0
16
0.00
0.41
0.0
1.1
—
1.2
—
0
5
(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose
0
16
0.00
0.41
0.0
1.3
—
7.6
—
0
10
(3023511) Choriogonadotropin [Units/volume] in Urine
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay
0
18
0.00
0.40
0.0
1.1
—
115.6
—
0
18
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
0
19
0.00
0.39
0.0
1.0
—
3.0
—
0
8
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
(4035726)
10
73
1.40
0.36
1.6
1.4
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
18
146
1.27
0.35
1.2
1.3
u/ml
2.9
6.3
—
9
54
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
13
102
1.31
0.31
1.3
1.7
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
31
351
0.84
0.31
1.7
1.9
pmol/l
84.7
95.4
0.64
18
165
(3013707) Erythrocyte sedimentation rate by Westergren method
72
676
1.16
0.30
6.6
3.8
mm/h
16.7
10.2
2.00
65
624
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
28
243
1.20
0.30
1.7
1.7
mmol/l
1.4
1.4
0.12
18
201
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
7
55
1.29
0.30
20.3
6.1
%
0.6
0.8
—
7
55
(3022145) Colonoscopy Study observation
8
108
0.72
0.30
1.8
1.3
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
8
109
0.71
0.30
10.5
7.0
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
7
56
1.27
0.30
20.3
6.0
%
1.3
1.6
—
7
56
(36660697) Celiac disease serology panel - Serum
5
72
0.68
0.27
1.2
1.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
9
75
1.22
0.25
1.3
1.8
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
5
37
1.37
0.24
1.6
1.3
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
37
1.37
0.24
2.4
2.4
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
5
38
1.33
0.23
1.6
1.3
—
—
—
0
0
(3044889) 12 lead EKG panel
67
635
1.13
0.22
5.9
3.5
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
11
0.00
0.21
0.0
3.3
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
0
11
0.00
0.21
0.0
2.5
—
106.5
—
0
11
(3041354) Potassium [Moles/volume] in Venous blood
0
11
0.00
0.21
0.0
2.5
—
3.9
—
0
11
(3024928) Oxygen saturation in Venous blood
0
10
0.00
0.21
0.0
9.9
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
10
0.00
0.21
0.0
2.6
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(4268621)
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay
0
14
0.00
0.20
0.0
1.0
—
100.9
—
0
14
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
6
50
1.21
0.20
1.7
1.9
ng/l
178.2
186.2
—
6
40
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
29
319
0.88
0.19
6.2
4.8
ug/l
3.4
2.0
0.50
22
286
(3026493) Urate [Moles/volume] in Serum or Plasma
27
244
1.14
0.18
3.1
2.9
umol/l
352.0
8863.9
1.47
19
209
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
11
130
0.83
0.17
1.5
1.7
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
39
363
1.11
0.17
3.3
2.2
nmol/l
69.8
73.3
0.43
34
320
(40768804) Tissue Pathology biopsy report
34
366
0.90
0.16
1.9
2.0
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
14
160
0.86
0.15
2.1
1.5
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
97
991
0.89
0.14
30.1
13.9
umol/l
78.9
78.5
0.06
97
991
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
87
893
0.90
0.14
4.5
4.4
mmol/l
6.3
6.0
1.00
76
811
(3022217) INR in Platelet poor plasma by Coagulation assay
13
114
1.16
0.12
16.8
22.9
—
1.2
—
0
15
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
70
677
1.08
0.12
4.0
3.7
pmol/l
15.3
14.8
0.79
60
611
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
86
881
0.91
0.12
26.0
11.3
ml/min/173m2
79.2
81.5
0.39
76
737
(3044640) Blood type and Crossmatch panel - Blood
26
280
0.91
0.12
3.9
2.1
—
—
—
0
0
(3022313) Gas panel - Capillary blood
5
46
1.09
0.10
40.8
2.5
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
5
48
1.04
0.09
3.8
3.0
pmol/l
4.1
4.5
—
5
41
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
10
89
1.13
0.07
1.4
2.0
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
99
1003
0.92
0.07
14.5
9.2
u/l
52.6
25.8
0.56
94
965
(40758558) Short blood count panel - Blood
24
229
1.06
0.04
8.5
7.4
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
11
101
1.10
0.04
1.6
2.1
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
99
980
1.06
0.04
26.7
11.1
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
11
118
0.93
0.03
1.4
1.4
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
84
848
0.97
0.02
19.7
12.6
%
39.9
40.2
0.09
44
635
(3017143) Hepatitis C virus Ab [Presence] in Serum
11
109
1.01
0.00
1.5
1.6
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
13
129
1.01
0.00
6.9
2.8
e6/l
0.8
1.2
—
7
69
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
3.9
—
0
5
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
6.7
—
0.6
—
0
6
(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
6
0.00
0.00
0.0
15.5
—
8.6
—
0
6
(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
0
5
0.00
0.00
0.0
7.8
—
—
—
0
0
(40758355) Pancreatic polypeptide [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.2
—
39.8
—
0
5
(3045788) Cell count panel - Pleural fluid
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.0
—
16.5
—
0
6
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
5
0.00
0.00
0.0
1.2
—
10.8
—
0
5
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
5
0.00
0.00
0.0
3.2
—
100.2
—
0
5
(3015183) Erythrocyte sedimentation rate
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
5
50
1.00
0.00
1.0
1.1
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
7
0.00
0.00
0.0
1.9
—
12.6
—
0
7
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
12
120
1.00
0.00
7.4
3.0
e6/l
4.0
1.7
—
6
61
(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3020491) Glucose [Moles/volume] in Blood
0
7
0.00
0.00
0.0
1.4
—
5.6
—
0
7
(3038026) Centromere Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(40761535) Cells panel - Urine sediment
8
79
1.01
0.00
1.6
3.4
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint J10_PNEUMOHAEM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PNEUMOHAEM | 2.174 [1.13, 4.17] | 0.019 |
| Birth year | 1.002 [0.99, 1.01] | 0.643 |
During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 195 females with J10_PNEUMOHAEM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PNEUMOHAEM | 3.488 [2.05, 5.92] | < 0.001 |
| Birth year | 0.985 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 208 males with J10_PNEUMOHAEM died.
Mortality risk
Mortality risk for people of age
years, who have J10_PNEUMOHAEM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.25% | 0.782% |
| 5 | 1.35% | 3.822% |
| 10 | 3.604% | 9.348% |
| 15 | 7.552% | 17.25% |
| 20 | 13.386% | 27.418% |
Relationships between endpoints
↥Index endpoint: J10_PNEUMOHAEM – Pneumonia due to Haemophilus influenzae
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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