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Pneumoconiosis due to other inorganic dusts

DOID EFO Endpoint Browser PheWeb

J10_INORGPNEUMOC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J63
  • Hospital discharge: ICD-9 — 503
  • Hospital discharge: ICD-8 — 51600
  • Cause of death: ICD-10 — J63
  • Cause of death: ICD-9 — 503
  • Cause of death: ICD-8 — 51600

2 out of 7 registries used, show all original rules.

134

4. Check minimum number of events

None

134

5. Include endpoints

None

134

6. Filter based on genotype QC (FinnGen only)

134

Control definitions (FinnGen only)

Control exclude
J10_EXTERLUNG

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J60-J70
Name in latin
Pneumoconiosis ex aliis pulveribus inorganicis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1874 796 1036
Only index persons 1034 447 587
Unadjusted period prevalence (%)
Whole population 0.03 0.02 0.03
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 72.58 76.03 69.86
Only index persons 68.26 72.40 65.11

-FinnGen-

Key figures

All Female Male
Number of individuals 134 40 94
Unadjusted period prevalence (%) 0.03 0.01 0.04
Median age at first event (years) 68.26 65.91 69.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
127
Matched controls
1269
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J63.3
ICD-10 Finland
Graphite fibrosis (of lung)
+∞
49.2
44
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
10.6
26.6
59
96
J63.8
ICD-10 Finland
Pneumoconiosis due to other specified inorganic dusts
+∞
24.8
23
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
12.4
23.0
44
52
J63.4
ICD-10 Finland
Siderosis
+∞
20.3
19
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
6.1
18.0
60
162
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
+∞
11.6
11
*
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
6.0
10.7
31
65
B01AC07
ATC
dipyridamole; systemic
5.1
9.1
30
73
J63.1
ICD-10 Finland
Bauxite fibrosis (of lung)
+∞
8.4
8
*
J63.0
ICD-10 Finland
Aluminosis (of lung)
+∞
8.4
8
*
51600
ICD-8 Finland
Other pneumoconiosis and related diseases, Due to inhalation of other inorganic dust
+∞
7.4
7
*
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
13.1
7.2
12
10
AA1AD
NOMESCO Finland
CT of head and brain
3.0
7.2
50
226
B01AC04
ATC
clopidogrel; oral
3.2
7.1
44
180
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
6.8
58
296
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
5.8
6.6
18
35
H53.4
ICD-10 Finland
Visual field defects
15.4
6.5
10
7
5030A
ICD-9 Finland
Pneumoconiosis due to other inorganic dust[PNEUMOCONIOSIS ALIA DEFINITA]
+∞
6.3
6
*
J63.5
ICD-10 Finland
Stannosis
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
14
48
3.14
3.41
4.8
6.0
mmol/l
25.9
24.5
0.73
14
48
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
18
73
2.69
3.29
1.9
1.7
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
7
11
6.64
3.22
2.4
2.4
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
12
41
3.12
2.94
10.7
8.8
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
18
90
2.16
2.12
2.4
1.3
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
21
356
0.51
2.10
5.6
4.7
%
23.3
21.8
—
8
179
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
9
34
2.76
1.90
1.1
1.4
—
—
—
0
0
(3026361) Erythrocytes [#/volume] in Blood
74
883
0.64
1.75
44.8
26.1
e12/l
4.4
4.4
0.06
74
849
(3035941) MCH [Entitic mass]
74
883
0.64
1.75
44.5
26.0
pg
30.3
30.5
0.24
74
863
(3024731) MCV [Entitic volume]
74
882
0.64
1.73
44.5
26.1
fl
92.4
91.8
0.48
74
862
(3007461) Platelets [#/volume] in Blood
74
881
0.64
1.71
44.6
26.1
e9/l
239.0
236.2
0.14
74
852
(40760888) Immunoglobulin light chains.free panel - Serum
6
19
3.25
1.68
1.2
4.2
—
—
—
0
0
(3000991) Gas panel - Venous blood
14
72
2.05
1.55
9.1
7.4
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
69
818
0.68
1.41
29.9
17.7
—
—
—
0
0
(3020891) Body temperature
9
41
2.28
1.40
1.4
3.9
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
10
48
2.17
1.31
2.0
2.2
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
6
25
2.46
1.26
2.2
3.2
kpa
5.2
5.2
—
6
25
(3027315) Oxygen [Partial pressure] in Blood
6
25
2.46
1.26
2.2
3.2
kpa
7.3
7.9
—
6
25
(3007853) Bacteria identified in Skin by Aerobe culture
18
111
1.72
1.19
3.7
2.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
51
402
1.43
1.17
19.6
10.4
inr
1.5
1.4
0.32
16
114
(3017732) Neutrophils [#/volume] in Blood
11
58
1.98
1.16
5.5
3.0
e9/l
3.4
3.5
—
6
43
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
12
66
1.90
1.13
1.5
1.5
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
18
113
1.68
1.12
10.2
9.6
—
—
—
0
0
(3003338) MCHC [Mass/volume]
51
623
0.71
1.12
36.4
24.3
g/l
327.9
331.3
1.40
51
617
(3034860) Kappa light chains.free [Mass/volume] in Serum
7
31
2.33
1.12
1.0
3.5
mg/l
45.5
70.5
—
7
25
(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma
7
31
2.33
1.12
1.0
3.5
mg/l
52.7
39.5
—
7
25
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
8
41
2.01
1.11
2.6
1.6
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
9
46
2.02
1.06
1.6
1.3
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
5
22
2.32
1.04
1.6
1.4
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
65
757
0.73
1.03
8.6
6.7
mmol/mol
44.3
41.6
0.93
60
687
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
55
448
1.39
1.03
9.2
7.1
mmol/l
1.2
1.2
0.11
45
370
(36304419) Bacteria [Presence] in Urine
33
245
1.46
1.03
4.6
3.0
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
9
50
1.86
0.99
2.4
2.6
g/l
9.4
10.4
—
9
40
(3004588) Protein electrophoresis panel - Serum or Plasma
12
70
1.78
0.96
1.3
2.3
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
33
249
1.43
0.94
2.2
1.8
nmol/l
1340.8
1187.3
0.56
25
189
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
65
747
0.75
0.89
30.0
17.3
ml/min/173m2
71.6
71.3
0.04
58
611
(3010421) pH of Blood
6
30
2.05
0.88
2.2
3.3
ph
7.4
7.4
—
6
25
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
75
844
0.75
0.88
15.4
10.8
u/l
22.2
22.7
0.18
75
802
(3020564) Creatinine [Moles/volume] in Serum or Plasma
76
853
0.75
0.87
32.3
21.4
umol/l
90.0
87.3
0.15
76
853
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
35
271
1.39
0.87
2.7
2.3
u/l
60.3
54.5
0.35
35
249
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
52
431
1.34
0.85
5.2
4.8
ng/l
31.7
58.7
1.47
44
336
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
8
46
1.79
0.84
2.9
1.8
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
42
338
1.35
0.82
4.7
3.2
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
70
791
0.76
0.82
5.9
5.2
mmol/l
2.2
2.5
2.17
64
701
(3009542) Hematocrit [Volume Fraction] of Blood
59
681
0.76
0.80
34.0
19.3
%
38.9
37.9
0.26
31
400
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
26
0.00
0.79
0.0
2.7
—
—
—
0
0
(1616796) Gas panel - Central venous blood
5
23
2.22
0.77
2.6
3.4
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
24
178
1.42
0.75
2.9
1.8
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
9
58
1.59
0.71
3.1
1.8
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
5
26
1.96
0.71
1.4
1.3
—
—
—
0
0
(40761535) Cells panel - Urine sediment
12
77
1.61
0.71
6.1
4.1
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
40
327
1.32
0.70
7.5
4.3
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
18
128
1.47
0.70
1.2
1.5
g/l
2.8
2.8
0.03
12
66
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
14
94
1.55
0.70
4.8
2.2
umol/l
4.1
10.6
2.20
14
83
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
68
762
0.78
0.69
5.1
4.6
mmol/l
3.9
4.3
2.82
62
682
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
70
780
0.79
0.67
5.8
5.1
mmol/l
6.5
6.1
0.62
62
681
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
68
756
0.80
0.62
5.2
4.6
mmol/l
1.3
1.4
2.24
61
668
(3029937) Albumin [Presence] in Urine by Test strip
30
243
1.30
0.56
7.4
4.5
estimate
0.0
0.0
0.00
13
72
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
42
356
1.26
0.56
3.2
3.6
ng/l
2884.9
2065.0
0.41
36
297
(3019060) Gas panel - Arterial blood
12
83
1.49
0.54
2.7
3.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
9
65
1.41
0.52
1.8
1.2
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
51
577
0.81
0.51
4.8
3.5
pmol/l
15.2
15.1
0.16
43
499
(3017143) Hepatitis C virus Ab [Presence] in Serum
8
58
1.40
0.42
1.8
1.4
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3017354) Segmented neutrophils/100 leukocytes in Blood
0
16
0.00
0.41
0.0
3.4
—
50.9
—
0
10
(3028308) Erythrocytes [#/volume] in Pleural fluid
0
16
0.00
0.41
0.0
1.3
—
54318.0
—
0
10
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
5
35
1.44
0.39
4.4
1.7
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
9
67
1.37
0.39
1.6
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
8
114
0.68
0.39
2.0
1.3
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
34
293
1.21
0.39
4.7
3.2
e6/l
70.2
296.4
0.50
29
227
(3005322) IgE [Units/volume] in Serum or Plasma
5
36
1.40
0.38
1.4
1.1
u/ml
15.2
133.9
—
5
30
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
11
146
0.73
0.38
4.4
3.0
e6/l
1.4
2.5
—
5
91
(4010399)
9
69
1.33
0.38
1.8
1.3
—
—
—
0
0
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
9
69
1.33
0.38
10.1
3.2
mmol/l
2.4
1.7
—
9
52
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
68
733
0.85
0.36
4.5
4.1
mmol/l
1.3
1.2
0.51
61
643
(36660697) Celiac disease serology panel - Serum
6
42
1.45
0.36
1.3
1.1
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
10
73
1.40
0.35
7.7
3.9
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
15
118
1.31
0.35
3.2
4.2
u/l
225.3
248.4
0.58
15
109
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
23
192
1.24
0.35
6.7
3.5
ng/l
172.9
239.5
0.15
18
169
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
6
44
1.38
0.35
1.0
2.8
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
17
137
1.28
0.34
1.3
1.1
u/ml
7.7
1.1
—
7
37
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
40
355
1.18
0.33
2.8
2.4
—
—
—
0
0
(3027945) Reticulocytes/100 erythrocytes in Blood
18
147
1.26
0.33
4.9
3.1
%
1.7
1.7
0.08
18
128
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
6
47
1.29
0.32
3.0
2.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
16
129
1.27
0.32
2.1
2.0
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
27
232
1.21
0.32
4.2
2.9
umol/l
355.0
3764.5
0.81
21
184
(3022313) Gas panel - Capillary blood
7
53
1.34
0.31
11.7
3.1
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
43
387
1.16
0.30
2.5
2.2
pmol/l
115.6
90.7
1.30
21
194
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
19
226
0.81
0.30
2.2
2.8
u/l
26.0
33.4
1.33
19
215
(3011397) Hemoglobin [Presence] in Urine by Test strip
21
177
1.22
0.30
6.2
4.6
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
31
272
1.18
0.29
2.5
2.2
mg/l
4.0
3.2
1.23
25
235
(3012516) Albumin [Mass/volume] in Urine
30
263
1.18
0.29
3.5
3.3
mg/l
1961.7
529.0
0.35
24
176
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
22
187
1.21
0.29
2.2
1.8
mg/l
0.7
1.7
2.39
16
149
(3044889) 12 lead EKG panel
54
583
0.88
0.27
5.4
4.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
37
333
1.15
0.26
6.5
4.4
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
9
75
1.21
0.25
10.4
3.1
kpa
5.5
4.9
—
9
66
(4035726)
6
82
0.72
0.25
1.3
1.3
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
5
37
1.36
0.24
1.4
1.2
—
—
—
0
0
(3012544) pH of Venous blood
11
88
1.27
0.23
1.7
4.2
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
5
39
1.29
0.23
6.2
2.6
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
14
116
1.23
0.23
2.9
1.8
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
16
188
0.83
0.23
1.4
1.3
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
12
98
1.25
0.22
1.2
1.3
iu/ml
103.4
45.0
—
7
36
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
14
117
1.22
0.21
2.9
1.8
—
—
—
0
0
(3017569) Oxygen content in Arterial blood
0
11
0.00
0.21
0.0
7.7
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(4146454)
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
3.3
—
76.0
—
0
12
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
13
0.00
0.21
0.0
5.0
—
—
—
0
0
(3019225) pH of Specimen
12
99
1.23
0.20
14.7
4.7
—
—
—
0
0
(3008898) HLA-B27 [Presence]
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3000492) Spirometry study
6
52
1.16
0.19
1.8
1.7
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
6
52
1.16
0.19
6.8
1.6
%
1.8
1.7
—
6
44
(3041096) Erythrocytes [Presence] in Urine by Automated
21
236
0.87
0.18
5.7
3.7
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
44
410
1.11
0.18
5.5
4.7
g/l
32.5
34.5
1.22
38
381
(40758558) Short blood count panel - Blood
22
196
1.15
0.18
7.0
6.9
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
7
62
1.14
0.17
3.4
3.5
—
0.5
—
0
19
(3009508) Creatinine [Moles/volume] in Urine
29
265
1.12
0.16
3.4
3.1
mmol/l
7.0
7.1
0.04
21
214
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
8
71
1.13
0.16
4.6
4.0
mmol/l
1.2
1.2
—
8
63
(46235355) HIV 1 and 2 tests - Meaningful Use set
10
83
1.22
0.16
1.7
1.5
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
30
325
0.90
0.15
2.1
2.1
—
—
—
0
0
(3013512) EKG study
27
294
0.90
0.15
5.1
4.6
—
—
—
0
0
(3002256) Pathology report gross observation
8
100
0.79
0.14
1.3
1.3
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
35
373
0.92
0.13
12.5
5.6
%
0.6
0.6
0.04
35
345
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
12
104
1.17
0.13
7.3
3.6
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
27
291
0.91
0.12
3.6
2.7
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
35
331
1.08
0.10
5.2
3.7
e6/l
32.6
54.8
0.57
30
252
(3018010) Neutrophils/100 leukocytes in Blood
36
378
0.93
0.09
10.1
5.5
%
62.5
59.0
0.89
36
352
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
6
55
1.10
0.09
1.2
1.8
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
18
195
0.91
0.08
1.8
3.5
—
—
—
0
0
(3018418) pH of Serum or Plasma
27
254
1.08
0.08
3.0
4.1
ph
7.4
7.4
—
8
49
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
5
63
0.79
0.08
1.2
3.0
—
63.0
—
0
23
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
7
65
1.08
0.08
2.6
1.3
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
36
376
0.94
0.07
12.3
5.7
%
2.3
2.8
0.82
36
348
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
8
92
0.86
0.07
4.6
2.8
ng/l
198.8
211.7
—
8
79
(42870588) Differential panel, method unspecified - Blood
28
294
0.94
0.06
10.9
5.3
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
32
307
1.06
0.05
5.5
3.7
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
58
594
0.96
0.05
7.2
4.8
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
18
191
0.93
0.05
2.4
3.1
mmol/l
2.4
2.5
0.34
11
166
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
34
329
1.04
0.04
2.6
2.1
nmol/l
80.6
75.4
0.54
27
275
(3020682) Albumin/Creatinine [Ratio] in Urine
29
280
1.05
0.03
4.6
3.9
mg/mmol
35.7
8.1
0.43
15
181
(3013707) Erythrocyte sedimentation rate by Westergren method
60
611
0.97
0.03
7.0
4.2
mm/h
21.1
14.9
1.45
55
554
(40760892) CBC W Ordered Manual Differential panel - Blood
17
161
1.06
0.03
5.7
4.4
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
37
378
0.97
0.02
12.8
6.0
%
8.1
9.0
1.04
37
351
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
21
217
0.96
0.01
3.4
2.8
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
31
306
1.02
0.00
3.7
3.3
mmol/l
2.3
2.3
0.42
21
265
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
38
382
0.99
0.00
4.9
4.8
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
41
408
1.01
0.00
6.2
4.2
estimate
0.0
0.0
0.00
13
80
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
15
153
0.98
0.00
3.9
2.8
e6/l
0.9
1.2
—
9
98
(3021601) Nitrite [Presence] in Urine by Test strip
41
409
1.00
0.00
6.9
5.6
estimate
0.0
0.0
0.00
13
77
(3009261) Glucose [Presence] in Urine by Test strip
41
415
0.98
0.00
6.2
4.2
estimate
0.0
0.0
—
9
73
(3002030) Lymphocytes/100 leukocytes in Blood
38
384
0.99
0.00
12.1
5.9
%
26.0
25.3
0.10
38
351
(3023511) Choriogonadotropin [Units/volume] in Urine
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3006442) Creatine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(44806420)
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(4268621)
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3014891) Appearance of Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3043410) Blood group antigens tested for on Red Blood Cells
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(4281824)
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
1.3
—
105.0
—
0
6
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045716) Anion gap in Serum or Plasma
0
6
0.00
0.00
0.0
3.8
—
8.7
—
0
6
(3003740) Influenza virus B Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000012) Reticulocyte production index
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
6
0.00
0.00
0.0
1.8
—
10.3
—
0
6
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3022145) Colonoscopy Study observation
7
79
0.88
0.00
1.6
1.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3022621) pH of Urine by Test strip
6
64
0.93
0.00
2.2
3.4
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
7
0.00
0.00
0.0
3.1
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(3004451) EKG impression Narrative
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint J10_INORGPNEUMOC and mortality.

Females

Parameter HR [95% CI] p-value
J10_INORGPNEUMOC 2.348 [1.93, 2.85] < 0.001
Birth year 0.996 [0.99, 1.0] 0.312

During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 557 females with J10_INORGPNEUMOC died.

Males

Parameter HR [95% CI] p-value
J10_INORGPNEUMOC 2.514 [2.05, 3.08] < 0.001
Birth year 0.985 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 496 out of 715 males with J10_INORGPNEUMOC died.

Mortality risk

Mortality risk for people of age

years, who have J10_INORGPNEUMOC.

N-year risk Females Males
1 0.211% 0.488%
5 1.365% 2.745%
10 3.496% 6.969%
15 6.78% 12.907%
20 11.869% 21.3%

Relationships between endpoints

↥

Index endpoint: J10_INORGPNEUMOC – Pneumoconiosis due to other inorganic dusts

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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