Cerebral atherosclerosis

I9_CEREBATHER

cerebral atherosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I67.2
  • Hospital discharge: ICD-9 4370
  • Hospital discharge: ICD-8 437
  • Cause of death: ICD-10 I67.2
  • Cause of death: ICD-9 4370
  • Cause of death: ICD-8 437

2 out of 7 registries used, show all original rules.

450

4. Check minimum number of events

None

450

5. Include endpoints

None

450

6. Filter based on genotype QC (FinnGen only)

450

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I67
Name in latin
Atherosclerosis cerebralis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13448 6688 6394
Only index persons 3338 1814 1524
Unadjusted period prevalence (%)
Whole population 0.19 0.19 0.18
Only index persons 0.06 0.07 0.06
Median age at first event (years)
Whole population 76.04 77.52 74.70
Only index persons 76.30 78.24 74.00

-FinnGen-

Key figures

All Female Male
Number of individuals 450 165 285
Unadjusted period prevalence (%) 0.10 0.06 0.13
Median age at first event (years) 73.48 73.82 73.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
391
Matched controls
3909
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I67.2
ICD-10 Finland
Cerebral atherosclerosis
10427.9
323.0
321
*
4370A
ICD-9 Finland
Other and ill-defined cerebrovascular disease, Cerebral atherosclerosis
+∞
40.3
38
*
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
4.5
21.0
82
219
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.8
18.7
88
277
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
4.0
18.3
81
241
43700
ICD-8 Finland
Generalised ischaemic cerebrovascular disease, With hypertension (benign)
+∞
17.8
17
*
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
9.7
16.8
34
38
43799
ICD-8 Finland
Generalised ischaemic cerebrovascular disease, Without mention of hypertension
+∞
15.7
15
*
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
7.2
15.7
38
57
AA1AD
NOMESCO Finland
CT of head and brain
2.6
15.4
139
676
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.9
14.4
103
432
B01AC04
ATC
clopidogrel; oral
2.6
12.9
113
532
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
5.0
12.7
41
89
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.4
12.1
44
108
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
9.6
11.1
22
24
5541
FHL
Subclavia and / or carotid endarterectomy, reconstruction or bypass surgery
17.2
9.9
15
9
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.8
9.7
41
117
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.2
9.1
34
87
B01AC07
ATC
dipyridamole; systemic
2.8
8.9
60
239
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
9.8
8.8
17
18
F01.9
ICD-10 Finland
Vascular dementia, unspecified
5.1
8.5
26
54
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
6.9
8.4
20
30
C10AA05
ATC
atorvastatin; oral
1.9
8.4
169
1107
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
8.8
8.4
17
20
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
7.8
150
961
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
9.6
7.3
14
15
TAB00
NOMESCO Finland
Lumbar puncture
5.5
7.2
20
38
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
4.3
6.9
24
58
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.5
6.8
53
230
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.9
6.7
39
142
XA800
NOMESCO Finland
Neuropsychological investigation
6.6
6.7
16
25
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.7
6.6
27
76
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
2.0
6.6
87
481
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.4
6.5
56
254
PA2YT
NOMESCO Finland
Cerebral artery PTA with stent
70.7
6.4
7
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3018677) aPTT in Platelet poor plasma by Coagulation assay
101
525
2.18
9.95
2.5
1.8
s
29.2
29.6
0.51
101
503
(3018418) pH of Serum or Plasma
154
1013
1.78
7.37
5.4
3.8
ph
7.4
7.4
0.07
44
195
(3012095) Magnesium [Moles/volume] in Serum or Plasma
88
501
1.93
6.59
2.5
2.9
mmol/l
0.8
0.8
0.77
79
458
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
198
1492
1.58
5.21
7.6
5.2
mmol/l
1.2
1.2
1.13
186
1320
(3035637) Corticotropin [Mass/volume] in Plasma
11
23
4.86
5.01
1.9
1.3
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
208
1621
1.52
4.51
7.9
6.0
mmol/l
1.2
1.2
0.93
160
1322
(3032080) INR in Blood by Coagulation assay
188
1439
1.52
4.41
11.6
12.6
inr
1.3
1.4
0.79
63
398
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
100
674
1.62
4.07
5.6
3.9
ng/l
514.8
226.3
0.29
90
594
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
92
612
1.63
3.94
1.9
1.8
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
51
288
1.86
3.89
5.1
3.8
mmol/l
1.2
1.2
0.70
45
242
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
177
1373
1.47
3.74
2.5
2.1
pmol/l
94.3
90.6
0.53
103
716
(3021960) Folate [Moles/volume] in Serum or Plasma
119
852
1.53
3.71
1.9
1.6
nmol/l
20.4
20.7
0.05
105
708
(3047181) Lactate [Moles/volume] in Blood
23
97
2.44
3.68
6.0
5.4
mmol/l
1.1
1.4
1.43
17
86
(3000991) Gas panel - Venous blood
49
282
1.82
3.53
8.6
7.3
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
110
789
1.52
3.37
1.9
1.8
nmol/l
1063.9
1173.3
0.67
84
579
(3004451) EKG impression Narrative
9
19
4.79
3.24
1.2
1.3
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
223
1846
1.40
3.16
7.4
4.7
mmol/l
7.2
6.9
0.73
211
1736
(3004789) Transferrin [Mass/volume] in Serum or Plasma
75
505
1.58
3.04
3.5
2.4
g/l
2.2
2.2
0.02
66
462
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
44
257
1.78
3.04
2.2
1.7
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
32
169
1.95
3.01
9.8
7.9
—
—
—
0
0
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
26
129
2.07
2.89
2.4
2.1
ug/l
576.4
883.3
0.28
26
120
(42870588) Differential panel, method unspecified - Blood
125
951
1.43
2.80
5.7
5.0
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
54
344
1.64
2.75
3.9
3.8
mmol/l
2.6
1.9
0.73
43
268
(3023368) Bacteria identified in Blood by Culture
137
1063
1.41
2.74
5.7
4.4
—
—
—
0
0
(1616796) Gas panel - Central venous blood
18
79
2.32
2.69
4.1
3.7
—
—
—
0
0
(3022948) Iron [Moles/volume] in Serum or Plasma
78
546
1.51
2.66
3.6
2.3
umol/l
9.3
11.8
2.80
70
502
(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay
0
69
0.00
2.62
0.0
3.8
—
526.6
—
0
64
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
19
87
2.23
2.59
1.4
1.4
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
190
1570
1.36
2.56
3.4
3.0
u/l
55.8
56.6
0.03
181
1428
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
13
50
2.64
2.53
2.2
2.0
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
57
377
1.58
2.50
5.8
4.0
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
104
781
1.43
2.48
1.9
1.8
pmol/l
443.3
9223736.5
0.50
87
618
(3020891) Body temperature
27
145
1.91
2.45
4.9
3.5
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
63
429
1.54
2.44
1.9
1.8
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
63
432
1.53
2.37
1.9
1.8
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
162
1322
1.35
2.32
5.5
4.4
—
—
—
0
0
(3043410) Blood group antigens tested for on Red Blood Cells
6
13
4.65
2.27
2.3
1.3
—
—
—
0
0
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
29
164
1.81
2.26
5.1
4.1
mmol/l
25.6
23.8
1.96
24
146
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
116
902
1.38
2.25
2.9
2.2
mg/l
2.8
3.3
1.66
105
755
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
45
290
1.61
2.21
1.8
2.1
g/l
0.2
0.2
0.37
40
261
(3019060) Gas panel - Arterial blood
42
266
1.63
2.21
5.2
3.6
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
61
424
1.50
2.16
7.5
5.8
mmol/l
1.3
1.3
0.00
54
324
(40761536) Microorganisms panel - Urine sediment
42
269
1.61
2.12
7.0
4.1
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
171
1426
1.31
2.07
6.0
4.1
g/l
33.2
34.2
1.21
159
1310
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
36
224
1.65
2.04
1.8
1.5
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
6
15
4.02
2.04
1.2
1.1
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
12
50
2.43
2.02
1.0
1.2
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
67
482
1.45
2.01
3.7
2.4
%
15.8
21.1
3.52
49
415
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
168
1403
1.31
2.00
6.1
4.3
ng/l
116.2
42.9
0.68
141
1094
(3021901) Oxygen saturation in Capillary blood
16
77
2.11
1.97
2.7
2.5
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
50
341
1.52
1.95
3.3
3.0
ng/l
247.5
283.6
0.22
42
313
(3018010) Neutrophils/100 leukocytes in Blood
154
1275
1.31
1.94
6.6
5.2
%
60.6
59.4
0.62
146
1176
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
17
85
2.03
1.91
1.1
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
17
85
2.03
1.91
1.1
1.3
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
134
1092
1.32
1.88
4.1
3.6
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
51
352
1.50
1.88
2.4
2.6
umol/l
5.3
9.5
3.36
44
310
(3019069) Monocytes/100 leukocytes in Blood
154
1280
1.30
1.87
7.0
5.5
%
8.8
8.9
0.07
148
1188
(3035350) Ketones [Presence] in Urine by Test strip
170
1432
1.29
1.87
5.2
4.3
estimate
0.0
0.0
0.00
41
283
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
189
1615
1.29
1.86
5.4
5.6
umol/l
11.5
12.5
0.70
176
1521
(3009343) pH of Capillary blood
36
230
1.61
1.86
2.6
3.6
ph
7.4
7.4
—
10
26
(3007853) Bacteria identified in Skin by Aerobe culture
52
362
1.49
1.85
2.1
1.8
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
153
1273
1.30
1.84
6.9
5.2
%
2.9
2.8
0.38
146
1173
(3023410) Appearance of Cerebral spinal fluid
6
17
3.55
1.83
1.0
1.2
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
169
1431
1.28
1.77
7.0
5.8
estimate
0.0
0.0
0.00
41
274
(3017315) Amylase [Enzymatic activity/volume] in Urine
5
13
3.86
1.71
1.0
1.0
u/l
571.0
141.0
—
5
13
(3004588) Protein electrophoresis panel - Serum or Plasma
40
268
1.53
1.71
1.7
2.2
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
139
1154
1.29
1.68
4.0
2.7
ug/l
113.6
162.5
3.00
130
1026
(3009261) Glucose [Presence] in Urine by Test strip
170
1448
1.27
1.68
5.2
4.3
estimate
0.0
0.0
0.49
39
269
(3022096) Basophils/100 leukocytes in Blood
148
1239
1.28
1.68
6.9
5.2
%
0.6
0.6
0.44
142
1144
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
23
134
1.75
1.67
3.3
3.1
—
—
—
0
0
(3016543) Leukocytes [#/volume] in Cerebral spinal fluid
11
49
2.27
1.63
1.4
1.1
e6/l
10.3
15.6
—
6
40
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
30
190
1.61
1.62
1.5
1.6
%
2.0
1.6
0.64
24
156
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
22
128
1.75
1.61
4.6
2.2
u/ml
0.3
0.3
0.08
16
70
(3027945) Reticulocytes/100 erythrocytes in Blood
61
451
1.40
1.60
3.4
2.5
%
1.8
1.8
0.07
56
398
(3006315) Basophils [#/volume] in Blood
160
1362
1.26
1.57
6.3
4.9
e9/l
0.0
0.0
0.09
137
1169
(3037756) Immunofixation for Serum or Plasma
16
85
1.91
1.55
1.1
1.4
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
153
1298
1.26
1.54
7.2
5.5
%
25.6
24.9
0.34
145
1189
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
14
71
2.00
1.54
4.5
1.5
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
16
86
1.89
1.51
1.2
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
16
86
1.89
1.51
1.2
1.2
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
229
2040
1.24
1.49
6.9
5.2
e6/l
17.4
3917.9
—
5
53
(3001604) Monocytes [#/volume] in Blood
158
1351
1.26
1.48
6.3
4.9
e9/l
0.6
0.6
0.08
135
1154
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
21
124
1.72
1.48
1.1
1.3
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
16
87
1.86
1.46
1.2
1.2
—
—
—
0
0
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
28
180
1.59
1.45
1.5
1.8
g/l
1.7
1.7
0.03
23
160
(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma
5
16
3.14
1.43
5.0
4.1
u/l
211.0
244.9
—
5
16
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
24
370
0.63
1.43
9.5
8.7
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
9
39
2.33
1.43
1.1
1.1
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
6
22
2.74
1.43
1.2
1.0
—
—
—
0
0
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
11
53
2.09
1.38
1.3
1.2
mg/l
463.0
536.6
0.37
11
48
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
52
385
1.39
1.37
1.3
1.2
iu/ml
18.6
44.0
1.99
19
126
(36304419) Bacteria [Presence] in Urine
108
892
1.27
1.35
4.3
3.5
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
125
1051
1.26
1.34
4.6
3.6
e6/l
41.2
149.9
1.06
93
823
(3005570) Glucose [Moles/volume] in Urine
9
42
2.16
1.34
1.3
2.4
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
162
1404
1.23
1.33
6.4
5.1
e9/l
0.2
0.2
0.37
142
1222
(3011397) Hemoglobin [Presence] in Urine by Test strip
82
655
1.30
1.32
4.1
4.3
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
31
209
1.51
1.32
3.2
3.8
%
0.0
0.1
—
8
69
(3013650) Neutrophils [#/volume] in Blood by Automated count
183
1610
1.22
1.29
7.7
7.9
e9/l
4.6
4.4
0.32
160
1398
(3019198) Lymphocytes [#/volume] in Blood
159
1379
1.23
1.29
6.6
5.1
e9/l
1.7
1.8
0.86
138
1207
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
39
279
1.43
1.25
2.7
2.1
u/l
30.1
32.8
0.24
33
219
(3037121) Protein [Mass/volume] in Urine
19
115
1.67
1.25
1.8
2.8
g/l
0.4
0.3
—
6
41
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
8
36
2.24
1.24
1.4
1.4
—
—
—
0
0
(4306422)
5
19
2.64
1.21
1.0
1.3
—
—
—
0
0
(3011648) Oxygen content in Venous blood
5
19
2.64
1.21
2.0
1.7
%
7.3
9.9
—
5
19
(3017181) Myelocytes/100 leukocytes in Blood
34
239
1.45
1.20
3.7
3.6
%
0.5
0.9
0.48
11
88
(3022313) Gas panel - Capillary blood
25
165
1.54
1.18
2.4
3.6
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
32
223
1.46
1.18
3.8
3.7
%
0.0
0.1
—
10
80
(3008295) Osmolality of Serum or Plasma
8
38
2.12
1.18
1.9
1.4
mosm/kgh2o
281.8
276.0
—
8
24
(3026179) Normetanephrine [Moles/volume] in Serum or Plasma
8
38
2.12
1.18
1.4
1.3
nmol/l
0.9
0.5
—
8
33
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
140
1208
1.22
1.18
4.3
3.6
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
225
2035
1.20
1.17
6.1
4.7
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
57
441
1.33
1.16
1.9
1.4
g/l
2.5
2.8
0.53
29
256
(3050449) Albumin [Mass/time] in Urine collected for unspecified duration
15
87
1.74
1.15
2.1
2.6
ug/min
14.8
84.7
—
8
55
(3024928) Oxygen saturation in Venous blood
13
72
1.82
1.15
4.5
2.8
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
21
134
1.59
1.15
1.3
1.3
—
38.1
—
0
9
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
16
95
1.70
1.14
1.4
1.6
—
—
—
0
0
(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
8
40
2.01
1.12
1.1
5.5
—
166.8
—
0
5
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
102
857
1.24
1.10
3.4
2.9
u/l
45.5
38.0
0.25
91
821
(3026782) Osmolality of Urine
88
728
1.25
1.09
3.2
3.2
mosm/kgh2o
551.9
559.4
0.12
74
613
(4024509)
5
21
2.39
1.09
1.4
1.5
—
—
—
0
0
(4035726)
35
253
1.41
1.08
1.3
1.4
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
10
52
1.94
1.06
2.9
3.6
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
9
45
2.01
1.05
3.0
4.1
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
7
34
2.07
1.03
1.3
1.4
nmol/l
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
29
205
1.44
1.02
2.9
3.6
%
0.3
0.5
—
8
61
(3003694) ABO and Rh group [Type] in Blood
75
615
1.26
1.00
1.4
1.3
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
17
107
1.61
1.00
1.2
1.3
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
43
328
1.34
0.98
3.7
2.6
e9/l
68.1
66.0
0.15
37
261
(3018095) Leukocytes [#/volume] in Urine
134
1173
1.20
0.96
5.4
4.2
e6/l
84.5
187.8
0.69
92
874
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
66
536
1.27
0.96
3.6
3.4
e6/l
6.0
2.3
0.39
32
314
(3041096) Erythrocytes [Presence] in Urine by Automated
95
805
1.22
0.95
5.6
4.0
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
68
555
1.26
0.95
4.6
4.7
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
51
401
1.30
0.95
3.8
3.6
u/l
228.6
248.1
1.05
46
375
(3045142) Bone marrow Pathology biopsy report
7
37
1.90
0.94
1.0
1.2
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
24
167
1.46
0.92
2.0
2.8
e9/l
4.5
3.8
0.55
19
111
(3030467) Casts [#/volume] in Urine by Automated count
109
940
1.21
0.92
4.4
3.5
e6/l
0.7
0.6
0.13
79
716
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
59
476
1.27
0.91
1.4
1.2
u/ml
0.8
1.2
—
10
126
(3021788) Differential panel - Synovial fluid
8
46
1.75
0.82
1.3
1.4
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
25
180
1.41
0.82
3.1
2.5
%
0.8
0.7
1.26
25
175
(3025941) Bacteria identified in Stool by Culture
23
163
1.43
0.82
1.2
1.3
—
—
—
0
0
(4094501)
11
65
1.70
0.82
1.1
1.1
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
6
32
1.88
0.81
1.0
1.0
u/ml
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
32
241
1.35
0.81
1.6
2.0
ug/g
149.0
163.7
0.12
27
194
(3030905) Polymorphonuclear cells [#/volume] in Blood
10
58
1.73
0.79
4.2
2.7
e9/l
4.0
4.8
—
10
58
(3010144) Erythrocytes [#/volume] in Synovial fluid
0
25
0.00
0.79
0.0
1.4
—
335122.2
—
0
18
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
137
1224
1.17
0.77
2.7
2.2
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
6
34
1.77
0.76
1.0
1.3
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
37
289
1.30
0.75
2.1
1.2
titre
233.8
496.3
1.29
13
59
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
94
817
1.19
0.73
6.0
4.6
estimate
0.0
0.0
0.00
39
267
(3048929) Epstein Barr virus Ab [Presence] in Serum
7
38
1.85
0.73
1.0
1.2
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
251
2650
0.87
0.73
5.9
5.0
mmol/l
6.3
6.2
0.90
231
2333
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
9
57
1.58
0.71
1.3
1.3
—
—
—
0
0
(3000012) Reticulocyte production index
5
26
1.93
0.70
2.0
2.0
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
15
101
1.50
0.70
2.3
4.0
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
127
1137
1.16
0.69
5.9
4.7
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
5
27
1.85
0.68
1.0
1.3
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
30
231
1.32
0.68
1.7
1.8
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
10
61
1.65
0.68
5.2
3.2
%
52.4
60.7
—
10
61
(3044941) Cell count panel - Synovial fluid
7
43
1.63
0.67
1.7
1.4
—
—
—
0
0
(3004775) Volume in Urine collected for unspecified duration
5
28
1.79
0.66
1.8
2.5
ml
583.0
515.8
—
5
18
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
65
553
1.20
0.65
3.7
3.2
e6/l
0.8
1.3
1.02
31
326
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
78
676
1.18
0.64
2.9
3.0
mmol/l
2.5
2.5
0.07
67
585
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
5
29
1.73
0.63
1.2
1.4
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
8
51
1.57
0.60
3.1
1.9
pg
31.0
32.8
—
8
51
(40758558) Short blood count panel - Blood
79
690
1.17
0.59
7.6
5.9
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
0
22
0.00
0.59
0.0
1.2
—
193.4
—
0
5
(3000850) Epithelial cells [#/volume] in Urine
84
740
1.16
0.57
4.1
2.8
e6/l
5.9
4.3
0.72
77
651
(3022145) Colonoscopy Study observation
36
293
1.24
0.56
1.3
1.3
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
275
2861
0.89
0.55
13.3
10.6
u/l
25.2
24.2
0.41
265
2727
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
15
107
1.41
0.55
1.2
1.8
u/l
31.7
39.5
1.30
15
91
(3013707) Erythrocyte sedimentation rate by Westergren method
224
2108
1.12
0.55
5.0
4.1
mm/h
14.5
15.8
0.58
213
1897
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
213
2000
1.12
0.54
4.2
3.7
pmol/l
14.7
15.1
1.41
195
1729
(3042111) Morphology [Interpretation] in Bone marrow Narrative
9
61
1.48
0.54
1.1
1.7
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
20
151
1.33
0.54
1.7
2.0
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
132
1206
1.13
0.53
16.1
10.4
e9/l
0.0
0.0
0.96
110
987
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
17
125
1.37
0.53
2.4
4.3
mmol/l
23.8
25.2
1.34
17
116
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
9
62
1.46
0.53
1.3
1.4
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
6
96
0.62
0.52
1.8
1.9
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
73
642
1.16
0.51
5.3
4.9
kg/l
1.0
1.0
0.61
19
98
(3045788) Cell count panel - Pleural fluid
6
40
1.50
0.51
1.3
1.4
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
31
251
1.25
0.51
4.9
3.6
ng/l
95.4
91.1
0.10
26
216
(3019832) Treponema pallidum Ab [Presence] in Serum
9
65
1.39
0.50
1.0
1.3
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
32
386
0.81
0.50
2.6
3.9
ug/l
2.5
39.5
1.18
26
335
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
66
745
0.86
0.50
2.6
3.1
ug/l
0.9
0.8
0.13
52
515
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
29
234
1.25
0.49
2.2
3.1
ml/min/173m2
54.2
57.6
—
10
103
(3026493) Urate [Moles/volume] in Serum or Plasma
88
788
1.14
0.49
3.3
2.8
umol/l
5192.9
8657.5
0.29
77
646
(3023419) Bacteria identified in Sputum by Culture
7
45
1.56
0.49
2.0
3.1
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
13
93
1.40
0.48
1.5
1.4
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
12
164
0.72
0.46
3.7
3.3
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
79
705
1.14
0.46
3.1
2.5
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
7
49
1.43
0.46
6.1
2.7
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
128
1181
1.11
0.44
2.6
2.2
nmol/l
78.9
78.5
0.06
118
1024
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
256
2655
0.91
0.44
6.6
5.3
mmol/l
2.2
2.5
5.07
248
2359
(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting
8
55
1.46
0.43
1.3
1.2
nmol/l
0.7
0.8
—
8
45
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
8
56
1.43
0.42
1.0
1.0
—
20.5
—
0
5
(3000963) Hemoglobin [Mass/volume] in Blood
287
2957
0.91
0.42
38.5
26.4
g/l
128.4
131.6
3.03
280
2886
(3026361) Erythrocytes [#/volume] in Blood
287
2956
0.91
0.41
38.2
26.2
e12/l
4.3
4.4
1.88
274
2842
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
15
0.00
0.41
0.0
3.9
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
(3035941) MCH [Entitic mass]
287
2955
0.91
0.41
38.0
26.1
pg
30.3
30.4
0.48
279
2889
(3007461) Platelets [#/volume] in Blood
287
2955
0.91
0.41
38.2
26.2
e9/l
243.5
235.6
1.04
273
2858
(3024731) MCV [Entitic volume]
287
2955
0.91
0.41
38.1
26.1
fl
91.7
91.9
0.25
279
2891
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
(3047189) Immunofixation for 24 hour Urine
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
(44806420)
0
18
0.00
0.40
0.0
2.3
—
—
—
0
0
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
7
104
0.67
0.40
1.1
2.6
u/ml
40.1
40.4
—
7
99
(40768797) Stomach Pathology biopsy report
43
373
1.16
0.38
1.2
1.3
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
25
206
1.22
0.37
2.4
2.5
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
19
234
0.80
0.37
1.4
1.3
—
—
—
0
0
(40768443) Skin Pathology biopsy report
10
135
0.73
0.37
1.4
1.2
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
71
640
1.13
0.37
2.0
1.7
mg/l
1.0
1.5
2.64
59
511
(3010813) Leukocytes [#/volume] in Blood
288
2958
0.92
0.37
38.1
26.2
e9/l
7.2
7.0
0.66
275
2843
(3000492) Spirometry study
24
198
1.22
0.36
1.8
1.5
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
5
77
0.64
0.36
1.4
1.3
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
6
42
1.43
0.35
1.2
1.4
u/l
228.7
239.8
—
6
42
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
26
218
1.20
0.34
1.5
1.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
16
198
0.80
0.33
1.4
1.4
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
6
47
1.28
0.32
1.3
1.2
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
10
131
0.76
0.32
4.9
5.4
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
249
2563
0.93
0.31
5.8
4.7
mmol/l
4.0
4.4
6.66
237
2298
(3015377) Calcium [Moles/volume] in Serum or Plasma
117
1094
1.09
0.31
3.2
3.0
mmol/l
2.3
2.3
0.01
104
934
(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma
7
55
1.27
0.30
1.1
1.2
u/l
20.7
60.4
—
7
46
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
247
2534
0.94
0.27
5.7
4.6
mmol/l
1.4
1.4
2.22
233
2242
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
8
66
1.21
0.26
1.4
1.5
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
102
956
1.08
0.26
3.0
2.6
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
8
67
1.19
0.26
1.3
1.4
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
5
72
0.69
0.26
1.8
2.6
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
9
72
1.25
0.25
1.0
1.1
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
17
201
0.84
0.25
3.8
4.7
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
99
1044
0.93
0.24
4.7
4.6
%
21.8
21.6
0.04
47
538
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
235
2275
1.06
0.24
8.5
7.0
u/l
78.1
81.8
0.63
222
2114
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
246
2516
0.94
0.23
26.1
17.5
ml/min/173m2
69.1
70.1
0.28
213
2101
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
12
97
1.24
0.22
1.2
1.0
—
—
—
0
0
(3008898) HLA-B27 [Presence]
5
40
1.25
0.22
1.0
1.2
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
5
40
1.25
0.22
1.0
1.2
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
286
2910
0.94
0.22
33.1
21.6
mmol/l
4.0
4.0
0.03
278
2813
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
42
1.19
0.21
1.4
1.4
—
—
—
0
0
(3005411) Squamous cell carcinoma Ag [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
3.0
—
2.8
—
0
5
(3001501) Glucose [Moles/volume] in Capillary blood by Glucometer
0
10
0.00
0.21
0.0
1.4
—
10.0
—
0
5
(3011288) Drugs identified in Urine by Screen method
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3010838) Calcium [Moles/time] in 24 hour Urine
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3044007) Cell count panel - Peritoneal fluid
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3008536) Aspergillus sp Ab [Presence] in Serum
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
286
2906
0.95
0.20
32.7
21.5
mmol/l
139.2
139.6
1.50
278
2810
(3013139) Helicobacter pylori Ag [Presence] in Stool
17
145
1.17
0.20
1.1
1.2
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
10
122
0.81
0.20
1.7
1.3
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
6
51
1.17
0.19
1.5
1.6
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
6
52
1.15
0.19
6.0
2.3
%
53.5
59.5
—
6
52
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
17
146
1.17
0.19
2.0
1.8
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
128
1227
1.06
0.18
3.5
3.2
ng/l
2673.2
2257.6
0.30
112
1058
(3003327) Ova and parasites identified in Stool by Light microscopy
7
62
1.13
0.17
2.0
1.4
—
—
—
0
0
(3022621) pH of Urine by Test strip
25
224
1.12
0.16
4.6
3.1
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
255
2492
1.05
0.16
5.5
4.6
mu/l
2.2
2.0
0.59
235
2175
(46235355) HIV 1 and 2 tests - Meaningful Use set
25
225
1.11
0.15
1.4
1.5
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
9
79
1.14
0.15
1.0
1.2
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
9
79
1.14
0.15
1.6
1.5
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
10
83
1.21
0.15
1.9
3.5
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
276
2795
0.96
0.15
25.1
17.3
—
—
—
0
0
(3044889) 12 lead EKG panel
207
2017
1.04
0.15
5.7
4.5
—
—
—
0
0
(4034850)
11
93
1.18
0.14
27.0
12.2
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
17
150
1.13
0.14
1.3
1.1
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
282
2768
1.04
0.13
26.7
18.2
mg/l
26.1
28.4
0.58
257
2297
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
15
132
1.14
0.12
1.9
1.6
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
243
2459
0.97
0.11
5.3
4.2
mmol/l
1.3
1.2
0.53
231
2159
(3003338) MCHC [Mass/volume]
212
2150
0.97
0.11
36.0
24.2
g/l
330.4
330.7
0.20
204
2124
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
129
1318
0.97
0.10
4.7
5.3
ug/l
2.4
4.3
1.12
114
1141
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
70
673
1.04
0.09
1.7
1.6
mmol/l
1.3
1.3
0.17
54
539
(4010399)
17
185
0.91
0.09
1.2
1.4
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
6
57
1.05
0.08
1.3
1.6
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
93
902
1.03
0.08
3.5
3.1
mmol/l
7.4
7.0
0.39
74
730
(3019225) pH of Specimen
27
286
0.94
0.08
2.5
3.5
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
106
1081
0.97
0.08
2.3
2.2
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
6
72
0.83
0.07
2.3
2.7
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
6
74
0.81
0.07
1.7
1.4
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
8
75
1.06
0.07
1.1
1.0
—
—
—
0
0
(3002256) Pathology report gross observation
39
372
1.05
0.07
1.2
1.3
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
37
356
1.04
0.04
1.4
1.2
u/ml
0.9
16.1
—
10
125
(3022217) INR in Platelet poor plasma by Coagulation assay
56
546
1.03
0.03
31.3
29.9
inr
1.6
1.5
—
5
63
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
255
2556
0.99
0.03
7.4
6.5
mmol/mol
42.4
41.8
0.41
246
2325
(1761868) Lipid panel - Serum or Plasma
74
748
0.98
0.02
4.6
3.4
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
11
112
0.98
0.00
1.4
2.2
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
49
490
1.00
0.00
2.3
1.9
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
91
907
1.00
0.00
3.6
3.1
mg/l
548.3
297.2
0.22
61
602
(3000494) Fungus identified in Specimen by Culture
31
309
1.00
0.00
1.5
1.4
—
—
—
0
0
(3013512) EKG study
101
1003
1.00
0.00
5.9
4.3
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
19
185
1.02
0.00
1.7
1.5
—
—
—
0
0
(40761535) Cells panel - Urine sediment
27
266
1.01
0.00
2.7
3.7
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
19
190
1.00
0.00
1.6
1.4
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
234
2335
1.00
0.00
31.0
19.6
%
35.8
37.9
1.37
143
1412
(3020682) Albumin/Creatinine [Ratio] in Urine
97
965
1.00
0.00
4.5
3.9
mg/mmol
11.9
10.3
0.11
68
614
(3016244) Insulin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
5.8
—
0
5
(42868499) Enterovirus IgG Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529188) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
7
78
0.89
0.00
1.4
1.3
—
—
—
0
0
(3027955) HFE gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004269) Kappa light chains [Mass/time] in 24 hour Urine
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3015076) Soybean IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017962) TCRG gene rearrangements [Presence] in Blood or Tissue by Molecular genetics method
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002067) Lambda light chains [Mass/time] in 24 hour Urine
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.0
—
119.0
—
0
5
(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
1444.8
—
0
5
(40760871) Heparin induced platelet Ab [Presence] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012741) Chlamydophila pneumoniae IgA Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000285) Sodium [Moles/volume] in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3025315) Body weight
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
(40762814) Titanium [Mass/volume] in Blood
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
7
0.00
0.00
0.0
2.6
—
13.7
—
0
7
(3018851) Theophylline [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
41.9
—
0
8
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
6
61
0.98
0.00
1.3
1.6
—
—
—
0
0
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022689) Creatine [Moles/volume] in Urine
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
5
52
0.96
0.00
1.4
1.6
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
5
50
1.00
0.00
2.0
1.3
—
—
—
0
0
(3012320) Pathologist interpretation of Cerebral spinal fluid tests
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
50
1.00
0.00
1.4
1.6
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
(3011335) Digoxin [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
8.7
—
0
6
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
49
1.02
0.00
1.0
1.1
—
—
—
0
0
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
6
64
0.93
0.00
1.2
1.5
mg/l
6.0
13.6
—
6
57
(3013005) Retinol [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
2.1
—
0
8
(3033799) Differential panel - Peritoneal fluid
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
8
79
1.01
0.00
1.3
1.6
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay
0
9
0.00
0.00
0.0
1.2
—
90.0
—
0
9
(3032057) Clostridioides difficile [Presence] in Stool
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
8
82
0.97
0.00
1.3
1.6
—
—
—
0
0
(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint I9_CEREBATHER and mortality.

Females

Parameter HR [95% CI] p-value
I9_CEREBATHER 2.047 [1.71, 2.45] < 0.001
Birth year 0.993 [0.98, 1.0] 0.133

During the follow-up period (1.1.1998 — 31.12.2019), 756 out of 1228 females with I9_CEREBATHER died.

Males

Parameter HR [95% CI] p-value
I9_CEREBATHER 2.466 [1.9, 3.21] < 0.001
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 656 out of 1080 males with I9_CEREBATHER died.

Mortality risk

Mortality risk for people of age

years, who have I9_CEREBATHER.

N-year risk Females Males
1 0.185% 0.353%
5 1.028% 2.747%
10 2.745% 6.72%
15 5.394% 11.925%
20 9.426% 19.076%

Relationships between endpoints

Index endpoint: I9_CEREBATHER – Cerebral atherosclerosis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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